https://oscb-berlin.org/the-oscb daily 0.75 2020-12-10 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc112eebc819f1cf4fdf526/1606488826431/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Tear-Film%2C-Tears-%26-Ocular-Surface_SCH%C3%96NE-%C3%9CBERSICHT-%C3%BCber-ALLE-THEMEN-der-Augenoberfl%C3%A4che_WEB-30_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a05395914e6b8a7f198e17/1503679413130/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a077d446c3c471fc5e395c/1503688695606/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a16c40cf81e085349b84d7/1503751328543/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f22451f9619a6187faab71/1509041240939/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif The OSCB ´‘Twarde’ soczewki kontaktowesą typowo mniejsze i spoczywają tylko na rogówce. Wymagają pewnego czasu adaptacji przez pacjenta i dlatego też są mniej chętnie noszone, niemniej wykonane są z wysokiej jakości materiałów zapewniających znakomite właściwości optyczne. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594f956cb11be16553f4f225/1498387828882/ The OSCB Stały Przepływ Łez na Powierzchni Oka(1) z miejsca ich głównej produkcji w gruczole łzowym poprzez (2) dobrze widoczną rogówkę i spojówkę, które muszą być stale nawilżone, po (3) system dróg łzowych odprowadzających łzy do nosa https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594bcac220099efbc56ec7ce/1498139360627/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f22634e2c483aeaffba3f1/1509041723760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS_LINK-Bildchen.gif The OSCB Niewystarczająca higienajest kluczowym czynnikiem ryzyka stosowania Soczewek Kontaktowych i skutkuje wyższym odsetkiem infekcji oczu u osób noszących soczewki kontaktowe.Mikroorganizmy mogą być wprowadzane przez palce użytkownika lub przez używanie wody z kranu, której należy unikać. Pewne typy drobnoustrojów występują również na normalnej powierzchni oka. Mikroorganizmy rosną na soczewkach i w pojemnikach do ich przechowywania i wytwarzają przyczepny biofilm chroniący je przez przed środkami czyszczącymi i przed usunięciem. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a07366579fb3e4063f09eb/1503687555131/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a675d1cd39c3b89e46ecef/1504081373790/OSCB-Berlin.org_BASIC-CAUSATIVE-FACTORS-for-DRY-EYE-DISEASE-are-a-LACK-of-Tear-PRODUCTION-and-of-Tear-FILM-FORMATION%2C-Neu---Einfach_.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a67758d482e9879760eb08/1504081778276/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aae1e4cd39c3b55f8b4d08/1504371233771/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59296b015016e1bf4188d1df/1495968612668/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a19a75197aea64f21a1062/1503763103905/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f1d8c5f6576e5c92ce6463/1509021924576/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c4f90246c3c4799e13cf82/1506081031135/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5941939fdb29d6dc42690bc9/1498073716626/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a19e83ccc5c5e77de75343/1503764123333/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594f9aa3cd0f68148ebcfd57/1498389162516/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a29e83f5e231745bb9bad1/1503829648233/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594bc602197aeafbe95dce52/1498138183633/OSCB-GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2820cm-72dpi%29_33-10fps+GIF.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac1532a803bb10bee98f87/1504449862100/OSCB-Bild_2_Meibomian+Gland_MGD_THERAPY%2C+Meibomian+Gland+EXPRESSION+-+with+the+own+FINGERS+%2B+SECRETUM_.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aadfd82994caa10188114c/1504370665103/OSCB-Bild_6.0_Dry+Eye+Disease_MGD%2C+THERAPY+for+Dry+Eye+incl.+MGD.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a193fbcd39c3181c3ef161/1503761416456/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM-Schmerz_Ocular-Surface-NERVOUS-SYSTEM-Pain_ENGLISCH_Einzel-BILDER_600pix-21-2_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594be033e6f2e11e9efccbc0/1498144847715/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5923284803596e4de56a2f67/1495975563601/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a29ee89f8dceb4db8a8e5c/1503829756734/OSCB-Bild_3.1.6_Only+a+MOIST+Cornea+can+stay+TRANSPARENT.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5952435215d5db6582ed1994/1498563662285/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594f923e099c01a39ee2957a/1498387035292/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif The OSCB Umiarkowane SUCHE OKOzazwyczaj objawia się tylko łagodnym zaczerwienienie spojówek i brzegów powiek, które jest wywołane przez stan zapalny, opisywany terminem´ "Keratoconjunctivitis Sicca". Ujścia łojowych gruczołów Meiboma są często zablokowane przez widoczną lub niewidoczną zagęszczoną wydzielinę (co stanowi najczęstszą pierwotną przyczynę Zespołu Suchego Oka). Objętość łez jest obniżona, a nabłonek Powierzchni Oka ma wiele drobnych ubytków, które wybarwiają się przy barwieniu fluoresceiną. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f220cfa9db098a38776c08/1509040350090/OSCB-Bild_9.3_Contact+Lens_Cell+ALTERATIONS+in+EXCURSION+ZONE+of+CL+%C3%9Cbersicht.png The OSCB Ultrastruktura nabłonkapowierzchni oka może ulec zaburzeniuna skutek oddziaływania soczewki kontaktowej. Pokazano tutaj zmiany nabłonka spojówki w strefie wypływu miękkiej soczewki kontaktowej. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a166bdf43b558cac63c9c3/1503749832757/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a19c2146c3c471fc6964fb/1503763497454/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e756ab9f07f52a3fe7d9e4/1508333237919/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f222592774d1b6f78aadfe/1509040738434/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ad6837d7bdcecfe12d9e1d/1504536655368/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a13d2b7131a5a6237c49af/1503739220794/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE+%2818cm-72%29_25-5fps_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a14c5c15d5dbae6514cd2d/1503743082710/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595bed696b8f5ba9a8309084/1499196819268/ The OSCB Ten schematyczny animowany diagram ilustruje zasadniczą funkcję powieki w rozprowadzaniu łez - faktyczne krople łez pojawiają się w szparze powiekowej tylko podczas zwiększonego wydzielania. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59233a13f7e0abe744aa44ac/1495975546652/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f0a2a864b05f532ce4b884/1508942523852/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5952b53336e5d31391ba1fbe/1498592578357/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592971eff7e0ab6406ba1938/1495965848611/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595bec256b8f5ba9a83082c1/1499196463262/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595bec763e00be98e380800a/1499196550200/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a67620d2b857a0be06eb19/1504081493051/ The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a05d1de58c623d4d433dad/1503681832771/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f1fc491f318d81dbf12b86/1509031176567/OSCB-GIF_9.3_ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2880-72%2C12-2%29+GIF.gif The OSCB Ruch Miękkiej Soczewki Kontaktowej na Powierzchni Gałki Ocznej i pod Powiekami. Soczewka kontaktowa porusza się przy każdym ruchu gałki ocznej, jak też podczas mrugania. Stopień mechanicznego tarcia na powierzchni oka jest typowo wyższy u noszących soczewki kontaktowe, nawet jeśli film łzowy jest wystarczający. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e72fc818b27d95efad371f/1508323292683/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a05c5cd55b4159c569a099/1503681637368/OSCB-Berlin.org_THE-OCULAR-SURFACE--%26--TEAR-FILM_%28quer-%2B-frontal-mit-BESCHRIFTUNG%29_WEB.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a18cb1ebbd1a0623d9a313/1503759549127/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye-Disease_Einzel-BILDER_500pix-30-2_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f1cec390bcce5ece05bb41/1509019340553/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif The OSCB Schematyczny diagram przedstawiający typową Miękką Soczewkę Kontaktowąśredniego rozmiaru na powierzchni oka, częściowo pod powiekami. Soczewki te nazywane są soczewkami rogówkowo-twardówkowymiponieważ część soczewki sięga poza rogówkę, na twardówkę… Jest to najczęściej używany typ soczewek kontaktowych. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc11c9a7acac6192ae86c0e/1606491304438/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a884c839140b7effcb300d4/1518882044610/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a884e02c83025f59a5b3fa1/1518968202255/Logo_DONATION-aus-Squarespace-HEARTBEAT.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a884d5f53450a6552dbf249/1518882215736/IMPROVE+YOUR+TEACHING_Folie6_ALS+GIF.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a884fe19140b7effcb397fa/1518882793585/EVER-LOGO-%2B-EVER-2018-Date___2.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc11fcc173fb5383bca3989/1606492123501/OSCB-Berlin.org_Bilder_Graefe-%C3%9C_OPT_2014-06-18-11_AUSSCHNITT-Hell_THE+GRAND+OLD+MAN_ALS+JPG_40+%2B+OSCB+Korn_.jpg The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59ddf26ec534a531cd8b58ea/59ddf88932601ef35adcb3a0/1507719308059/18tth-CONFERNCE-on-Pharmacology_AlliedAcademics.com___KONGRESSBANNER_EYE_WEB-2_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59ddf26ec534a531cd8b58ea/59ddf6de268b96261dbc9af9/1507718882747/18tth-CONFERNCE-on-Pharmacology_AlliedAcademics.com___KONGRESSBANNER_ROME_WEB_.gif The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59ddf26ec534a531cd8b58ea/59ddf26f017db238d498c400/1507717746433/18tth+CONFERNCE+on+Pharmacology_AlliedAcademics.com___KONGRESSBANNER_.jpg The OSCB https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a8844aee4966ba44fc3f9b7/1606477414058/The-Tear-FILM-%26-The-OCULAR-SURFACE__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU_OB-WEG-f%C3%BCr-LINK-Bild.gif The OSCB The Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5a883f1cc83025f59a58d166/5a88404b41920223d052caf6/1518879146084/TROCKENES+AUGE%2C+DRY+EYE+W%C3%BCste+mit+Kamelen_LINK+Bild_+.jpg The OSCB - Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5a883f1cc83025f59a58d166/5a88400b24a694d707928f16/1606477617595/WasserTROPFEN%2Bauf%2BBlatt%2Bwie%2BTr%C3%A4nen%2C%2BOPT%2BBREITER%2B_Fr%C3%BChjhar%2B2016_LINK+Bild_.jpg The OSCB - Tears 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Der Lidschlag bildet aus der Tränenflüssigkeit den Tränen-Film. Störungen des regelrechten Lidschlages sind also ein typischer Grund für Störungen des Tränen-Film und damit für ein Trockenes Auge ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f40001d8368c5666a3358ba/1598029920952/Animation-OFFICE-EYE_400-12-0%2C4_OSCB-Berlin.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5f2043caafb27f44fb3ce0/1600069710249/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_10-11-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0c5aa0fe97c9602d28c9a8/1594736018342/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che%2C+FOTO%2BSCHEMA_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b352fa8758d46d1dc85c3ea/1532291687008/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca0da3153450a615e5aa793/1567176374003/Animation_Trockenes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5cc255ce23ec19f7d4b811/1599914589927/OSCB-Berlin_%C2%A9-ENK_UNSCHARF-SEHEN---do-you-also-suffer-%2B-BLINK%2C-Blinzeln_4_10-17-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b264c1a70a6ad7fc90e46b5/1529244871759/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df4a6470027c563449aeb5a/1580040619972/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df4d0e34b14fd7c686f8bfb/1580040619958/OSCB-Berlin.org+-+%28c%29+ENK_Bildung+von+ABLAGERUNGEN+auf+dem+Lidrand_ANIMATION+-+EINZELBILD+daraus_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca1124d419202a10bf0e8d5/1567176374014/Henrik+SJ%C3%96GREN_Download.jpg FAKTEN über das TROCKENE AUGE Henrik SJÖGREN, schwedischer Augenarzt, der als erster die nach ihm benannte entzündliche Erkrankung der Tränen- und Speicheldrüsen beschrieben hat, die zum Sicca Syndrom von Auge und Mund führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6d3dbfe4f17a0001b1d35c/1580040619967/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg FAKTEN über das TROCKENE AUGE Die Meibom-Öldrüsen in den Augenlidern bilden normalerweise (links) Öl für den Tränenfilm, das die Verdunstung des Tränenwassers hemmt. Wenn die Öldrüsen verstopft sind (rechts) verdunstet das Tränenwasser schnell und es kommt zum Trockenen Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5ca0b8d7bf523730bf673a/1599905985919/OSCB-Berlin.org_%28c%29-ENK_Animation-AugenBewegung%2C-Mechanische-Reibung%2C-Fremdk%C3%B6rpergef%C3%BChl-%2BGranula-%2Bgelber-Zettel_10-12-0%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b2f786f575d1fd783a24d7f/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56a12e05b2700001a60ce3/1581975191064/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg FAKTEN über das TROCKENE AUGE => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b25505788251ba762cc077b/1529244871746/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df4b9b54f4ce57dd231f339/1580040619964/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6e30c6b91b0c000108ee1a/1580040619969/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_+%281%29.gif FAKTEN über das TROCKENE AUGE Inkompletter Lidschlag https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f14608580c8be6ffebd1358/1596803965631/Information-6-SCHADEN_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f1460853546c13c466f9081/1596803965627/Information-2-BESCHWERDEN_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f1460844b808c140f7022ba/1596803965624/Information-3-URSACHE_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f146083cd0e0c7efbcfe73f/1596803965618/Information-4-RISIKO-FAKTOREN_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f14608340592a3871a28e7b/1596803965614/Information-5-TROCKENHEIT_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f14608255e4ba6ef22d2924/1597058729948/Information-7-VERSCHLIMMERUNG_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f146082519fe519ddde8b41/1597058718691/Information-8-THERAPIE_Neu2_.jpg FAKTEN über das TROCKENE AUGE - THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1460362a4010553e8bfd08/5f14603786531d20ab70f5ea/1596803965595/Information-1-WAS+IST_Neu2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b367e96575d1f8ffa45c3a2/1567502777033/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b262095758d468433e1988b/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b264b3d8a922d27105bfc32/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b254184aa4a99e2ba1c5a83/1529244871748/GIF+Animation_Typische+Symptome+beim+Trockenen+Auge_Bild+4v4_20-72_4-0.5fps_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3ffe2e97d1a73c934d75c4/1598029419779/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNE+Risiko+Faktoren+f%C3%BCr+Trockenes+Auge_10.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b2fb9d88a922d7f9cdda36d/1529869348309/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5c9f189e32a319f5218127/1599905576254/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2C%2B_Trockenes%2BAuge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C%2BGewebe%2BReizung_NEU_OHNE%2BText+%2BFlammen_10_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df50eb4460f77349da22755/1580040619975/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung_Animation--DEUTSCH-600-2-0%2C5_NEU-anderes-Bild_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b2513576d2a73b36bab239b/1529244871744/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f1810477c16870b7bfca18d/1604487203137/OSCB-Berlin.org_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%28aus-KL-Weich%29_VERKL.-25br-x-25cm-%2BNEU-MAN_Zettel-10-10-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fb6bfcc56d15046bd030335/5fb6c0f57f6bdd7c9034bc95/1605812509662/Das%2BTrockene%2BAuge%2Bist%2Beine%2BVERZWICKTE%2BErkrankung_20%2BLink%2BBildchen+%281%29.jpg FAKTEN über das TROCKENE AUGE - VERZWICKTE Erkrankung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fb6bfcc56d15046bd030335/5fb6c08a2d0951511e792550/1605812453695/OSCB-Berlin.org---%28c%29-ENK_LIDRAND%2BIMG_0287%2BRET%2B%2B%2BGelber%2BZettel_10%2BLINK%2BBILDCHEN%2Bheller_+%281%29.jpg FAKTEN über das TROCKENE AUGE - Augen LIDER https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fb6bfcc56d15046bd030335/5fb6c04a6e09003e8138c3c6/1605812434898/OSCB-Berlin.org_%28c%29%2BENK_LIDER-%28FRONTAL%29-Animation%2C%2BBLINZELN_%2BTr%C3%A4nenfluss-mit-Gelbem-Zettel_FEUCHTES-Auge%2C-Epiphora_10-10-0%2C2_.gif FAKTEN über das TROCKENE AUGE - FEUCHTES Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fb6bfcc56d15046bd030335/5fb6bfcd0b955413a41c49af/1605812629935/OSCB-Berlin.org---%28c%29-ENK_Kennen%2BSie%2Bdas%2Bauch%2C%2BDo%2Byou%2Balso%2Bsuffer%2B%2B%2BGelber%2BZettel_10%2BLINK%2BBILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - TROCKENES Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d85ef6b4f66404594329884/1580142427695/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye+Disease%2C+Trockenes+Auge_OSCB-Bild_6-Dry+Eye_Lid+and+Blinking+Deficiency+%28LBD%29_ENTROPION_20_.jpg FAKTEN über das TROCKENE AUGE Rollung des Lidrandes nach innen (Entropium) mit Reiben der Wimpern auf dem Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f1847ae428c111f706a4e7b/1604487203140/OSCB-Bild_6-Dry+Eye_Lid+and+Blinking+Deficiency+%28LBD%29_ECTROPION%2C+FRONTAL+%2B+TEMPORAL_ohne+Text_10_.jpg FAKTEN über das TROCKENE AUGE Abstehendes Unterlid mit Rollung des Lidrandes nach aussen (Ektropium) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d85f1c71d47f936913539ca/1580142427684/Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME%2B-UNSCHARF_NEU-KLEINER-20-23-1_.gif FAKTEN über das TROCKENE AUGE . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d6fc88251b3e9851097c/1509125946453/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__DOKTOR%2C-meine-Augen-sind-doch-FEUCHT-...-wie-kann-das-ein-TROCKENES-AUGE-sein.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae5930e0e2e72dfd9fd6a06/1567176420519/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5fa044c99692130909c2c0/1604487203143/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_10-11-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d6fc88251b3e9851097e/1509125946454/OSCB-Berlin.org_Das-TROCKENE-AUGE-ist-eine-verzwickte-Erkrankung_Kartenhaus.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5f653c02b4ba0be61e6436/1604487203130/OSCB-Berlin.org+%28c%29+ENK_INHOMOGENIT%C3%84T-des-Tr%C3%A4nenFILMs-st%C3%B6rt-die-Sehsch%C3%A4rfe_10_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56a1f1b2f793000139330c/1567176420517/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg FAKTEN über das TROCKENE AUGE => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5387a8562fa73754db824a/5b53895903ce640bec6de18e/1567176420541/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg FAKTEN über das TROCKENE AUGE - TIEFERER EINBLICK in den wissenschaftlichen Hintergrund https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5387a8562fa73754db824a/5b5388cbf950b7144196b276/1567176420539/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE - ÜBERBLICK für die klinische Basis https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5387a8562fa73754db824a/5b5387a9352f530b8e2320b5/1567176420533/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE - KURZER BLICK&nbsp;- für den ersten Eindruck https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f32708ba5927e511585331f/1597141144570/OSCB-BILD_Augenoberfl%C3%A4che_EIN+NEUER+BLICK+auf+die+AUGENOBERFL%C3%84CHE++...BASIC+FUNCTIONAL+COMPLEX+%28%C3%9Cberblick+Funktionelle+Komplexe%29_20usm_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f357c016e7e7a0c7d986644/1597340688844/OSCB-Bild_6.0_Dry+Eye+Disease_Tear+Film+Deficiency+TR%C3%84NENFILM+MANGEL+-+Potential+MIXTURE+of+individual+Types+into+MIXED+TYPE_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b563aad03ce64edc84806c4/1567176507704/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56a286b09c7a0001a3995a/1567176507701/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg FAKTEN über das TROCKENE AUGE => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8b47897c1cc52e138c4e41/1580331342978/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+GRAD+10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d96182c81c7d3352141561a/1580331342956/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+MUZIN-MANGEL+auf+PFEIL+ISOLIERT_OHNE%2BBilder_20_DEW270_NEU_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d90f591b876135bf04e909e/1580331342945/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+PRIMARE+Pathologie+%2B+SEKUND%C3%84RE+pathogenetische+Faktoren+MIT+KAUSALEN+Faktoren+oben+%2B+DR%C3%9CSEN-KREISEN+Sek.+LEER+DEW241_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d91ca6cd1f78e78c2ebc912/1580331342953/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+LIDSCHLAG+ST%C3%96RUNG%2C+LBD%2C+auf+PFEIL+ISOLIERT_OHNE%2BBilder_20_DEW270_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d761063a6aa9d1c2f38a3c4/1580331342969/OSCB-GIF_ABSCHLUSS+VICIOUS+CIRCLES+%28aus+Dry+Eye+Concept%29_30-72_7-1_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d94cdb117c5172ba504fecf/1580331342934/GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_600pix-12-1%2C5_NEU%2BSchatten-OPT_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d753722a677d754f453b0b2/1580331342961/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_SEKUND%C3%84RE+pathogenetische+Faktoren+GEWEBESCHADEN+DEW238_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b701e3cf950b71d4a6af744/1567176507741/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d9113684cd9ba4e70f396bf/1580331342951/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+LIPID+%C3%96L+MANGEL+auf+PFEIL+ISOLIERT_OHNE%2BBilder_20_DEW270_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d91cef0f81c5b0c17306049/1580331342959/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+SEKUND%C3%84RE+pathogenetische+Faktoren+-+KAUSALE+Faktoren_DEW241_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8b54ce121b9246876c8742/1580331342980/OSCB-Berlin.org_%28c%29-by-ENK-Erich-u-Nadja-Knop_Dry+Eye%2C+Trockenes+Auge_OXFORD+Scheme+for+Vital+Staining%2C+Vitalf%C3%A4rbung%2C+Cornea+Epithelium+Kornea%2C+Hornhautepithel_20_.jpg FAKTEN über das TROCKENE AUGE 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c2b8029aa4a995f08bfaced/1567176507772/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe%2BScientists_10%2BLINK%2BBILDCHEN_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d91134fe28e135d10627901/1580331342948/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+W%C3%84SSRIGER+MANGEL+auf+PFEIL+ISOLIERT_OHNE%2BBilder_20_DEW270_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b701e024ae2373e2b025244/1567176507739/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0c16b88251b975ed3b536/1521266491492/GIF-Animation-GRUNDLEGENDE-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE_DEUTSCH_Einzel-BILDER_400pix-32-2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6c0c684111190001259846/1580331342966/OSCB-Berlin.org%2C+%28c%29+ENK_Ocular+Surface+%26+Dry+Eye_Augejoberfl%C3%A4ch+%26+Trockenes+Auge_EINFLUSSFAKTOREN_20_JPG6_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5ae0c16b88251b975ed3b52d/1568208868383/OSCB-Berlin.org_Grundlegende-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE-sind-ein-MANGEL-von-Tr%C3%A4nen-PRODUKTION-und-von-Tr%C3%A4nen-FILM-BILDUNG---EINFACH--NEU_WEB_LINK-Bildchen.gif FAKTEN über das TROCKENE AUGE - KAUSALE Faktoren 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5aedd432575d1f65bde10390/1568215661761/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_START3_.jpg FAKTEN über das TROCKENE AUGE - KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d78fc6b02c6694c68ef353b/1580331342907/OSCB-Berlin.org%2C+%28c%29+ENK_Ocular+Surface+%26+Dry+Eye_Augenoberfl%C3%A4che+%26+Trockenes+Auge_EINFLUSSFAKTOREN%2C+RISK+FACTORS_10+LINK+BILDCHEN_JPG6_.jpg FAKTEN über das TROCKENE AUGE - Einfluss-FAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d78f7fa30a4000d09e53866/1580331342900/Prim%C3%A4re+PATHOLOGIE%2C+TR%C3%84NENMANGEL+ist+meist+ZUERST+und+GEWEBESCHADEN+nachfolgend_Neu+DEW236_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - Primäre PATHOLOGIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d78fa3a30a4000d09e56e3f/1580331342904/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_SEKUND%C3%84RE+pathogenetische+Faktoren+GEWEBESCHADEN+DEW238_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - GEWEBE-Schaden https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d790ea23a3c97200155051d/1580331342911/OSCB-GIF_DEWS-II._PPT-VORLAGEN_-20%25-KOPIE%2B10hoch_4-Basteln_VICIOUS-CIRCLE-GLAND-DYSFUNCTION_9-19_360-5-0%2C7_.gif FAKTEN über das TROCKENE AUGE - Vicious CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d7a89b9b569a616547ad25b/1580331342913/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif FAKTEN über das TROCKENE AUGE - Typische SYMPTOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d8a2511ca49b978bf9e3370/1580331342917/OSCB-Berlin.org_Klinische%252BBEFUNDE%252Bbeim%252BTrockenen%252BAuge.jpg FAKTEN über das TROCKENE AUGE - Wichtige BEFUNDE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d8a258fca49b978bf9e4189/1580331342920/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_3_.jpg FAKTEN über das TROCKENE AUGE - DIAGNOSTIK https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d8b57b7cd9b01713092e93e/1580331342923/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+GRAD+10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - THERAPIE Schema https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d8b57f8451b7e243ce2c03a/1580331342926/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+TEXT_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - SCHWERE Grad https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d95b423a0bfc672d821470b/1580331342929/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+PATHOPHYSIOLOGIE+-++PFEILE+_10_DEW271_.jpg FAKTEN über das TROCKENE AUGE - TRÄNENFILM Mangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae0c16b88251b975ed3b524/5d95b515b66302713d8a0173/1580331342932/GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_10-12-1%2C5-NEU%2BSchatten-OPT_.gif FAKTEN über das TROCKENE AUGE - Grund-FUNKTIONEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae87eed352f53431734621f/1567176507735/GIF+Animation_Typische+Symptome+beim+Trockenen+Auge_Bild+4v4_48-72_4-0.5fps_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8a22a2358ba566026d21f0/1580331342972/OSCB-Berlin.org_Klinische%2BBEFUNDE%2Bbeim%2BTrockenen%2BAuge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae8354faa4a994ac03de0a5/1567176507722/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE+%2818cm-72%29_25-5fps_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d769861559c0539f0865f76/1580331342964/OSCB-Berlin.org_Die+wichtigsten+Faktoren+in+der+Tr%C3%A4nenfilmst%C3%B6rung+die+das-Oberfl%C3%A4chengewebe+sch%C3%A4digen+beim+Trockenen+Auge+sind+Chronisch+MECHANISCHE+REIBUNG+und+HYPER+OSMOLARIT%C3%84T_20_ALS+JPG_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d75545b61770c1847f01cbf/1580331342937/OSCB-Berlin.org_FEINSTRUKTUR-der-AUGENOBERFL%C3%84CHE-und-TR%C3%84NENFILM+%2B+PSE+AUSSCHNITT+Mikrovilli+u.+Muzin_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8a21f8358ba566026d11c1/1580331342975/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_3_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c6a/1509125946497/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif FAKTEN über das TROCKENE AUGE Der kontinuierliche Verlauf der Tränen über die Augenoberfläche, der für ihre Gesundheit von grösster Wichtigkeit ist, geht (in der Abbildung von links nach rechts): (1) vom Hauptproduktionsort in der Tränendrüse über (2) die sichtbare Hornhaut/ Kornea und Bindehaut/ Konjunktiva, die ständig gebadet werden müssen, in (3) die Ableitenden Tränenwege, die die ´gebrauchten´ Tränen in die Nase ableiten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c68/1509125946495/ FAKTEN über das TROCKENE AUGE Die FEUCHTIGKEIT der Augenoberfläche ist nötig, um die Hornhaut/ Kornea TRANSPARENT zu halten https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c78/1509125946509/ FAKTEN über das TROCKENE AUGE Interessanterweise ist die Bildung der Ölschicht des Tränenfilms von grösserer Bedeutung als die Bildung von Tränenwasser, da bei Öl-Mangel auch reichliches Tränenwasser schnell verdunstet. Es entstehen dann Lücken im Tränenfilm und die empfindlichen Zellen der Augenoberfläche werden geschädigt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c64/1509125946492/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c6e/1555257764514/ FAKTEN über das TROCKENE AUGE Ein BLICK IN DEN TRÄNENFILM. Der mittlere Hauptteil des Tränenfilms vor der transparenten Hornhaut/ Kornea besteht aus wässriger Flüssigkeit. Unten sind die zahlreichen fingerartigen Fortsätze der oberflächlichen Epithelzellen sichtbar - sie binden das Wasser an die Zell-Oberfläche. Im Tränenfilm wird das Wasser durch die langen Zuckerketten (hier rötlich) löslicher Schleimstoffe (Muzine) gebunden, die im Tränenfilm treiben und das Wasser in ein dünnflüssiges Wasser-Muzin-Gel verwandeln. Oben wird der Tränenfilm von der sehr dünnen Öl-Schicht aus den Fetten der Meibomdrüsen abgedeckt, die eine zu schnelle Verdunstung des Tränenwassers verhindert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf95eb895f0880001766c69/1567176570842/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-2x-3D-%C3%96L_NEU-HH%2BIRIS-3D-%2BHH-WEISS-WEB_2_20_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d862f561d47f93691385bf9/1580331818969/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d862cba4f6640459435a399/1580331818979/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df3f16991da223324d1df94/1580331818961/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c85/1509125946517/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d862df44f6640459435b859/1580331818976/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c72/1509125946504/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c8f/1509125946524/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5cb20770a6addd33b7eb2c/1567176570800/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7665cd4b2a937008f3de67/1580331818964/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM_NUR-BLINZELN-9-19_500-16-1_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c7e/1569330809562/OSCB-Berlin.org_Klinische+BEFUNDE+beim+Trockenen+Auge.png FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d94f46a59622a32ba665b53/1580331818946/OSCB-Berlin.org_FEINSTRUKTUR-der-AUGENOBERFL%C3%84CHE-und-TR%C3%84NENFILM+%2B++PSE+AUSSCHNITT+Mikrovilli+u.+Muzin.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5babb6078165f5f5885801dd/1567176570854/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7281c39dd27a7134e4a2e9/1580331818953/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+SQUAMOUS+METAPLASIA_Trockenes+Auge%2C+PLATTENEPITHEL+METAPLASIE+%28LM%2BSEM%29_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c76/1509125946507/ FAKTEN über das TROCKENE AUGE Die beiden grundlegenden Voraussetzungen für die Gesundheit der Augenoberfläche und für das intakte Sehen sind die Bildung von Tränenflüssigkeit und die Herstellung eines stabilen Tränenfilms daraus. Entsprechend sind die beiden wichtigsten Faktoren für die Entstehung eines Trockenen Auges ein Mangel an Tränenflüssigkeit und/ oder ein Problem bei der Herstellung eines ausreichend stabilen Films daraus. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d94f3e880d5f70f5dd944e8/1580331818950/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Die-Augen-Bindehaut-Konjunktiva-hat-eine-empfindliche-Oberfl%C3%A4chenstruktur%2C-Epithel-mit-Becherzellen%2C-Mikrovilli-und-Glykokalyx-%28Koloriertes-LM-%2B-TEM_ALS+JPG_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f40fb2969f0cd7cfbcddfb8/1598094134585/OSCB-Berlin.org_%28c%29ENK_Regulatorische-Systeme-mit-ZETTEL-2_10-2-0%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c7a/1509125946511/OSCB-Berlin.org_GIF-Animation_Typische-SYMTOME-beim-Trockenen-Auge_Bild-1-4v4_10-72_6-x2sec-PSE__.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c81/1509125946516/ FAKTEN über das TROCKENE AUGE Die Neuronale Regulation der Augenoberfläche, über die Hirnnerven V (Trigeminus) und VII (Facialis) im Hirnstamm, und auch ihre Emotionale Wahrnehmung im Gehirn ist komplex. Damit ist sie anfällig für Störungen, kann aber auch gewisse individuelle Unterschiede zwischen verschiedenen Menschen zeigen. Hier gehen auch Erfahrungen, Bewertungen und verschiedene Arten der Bahnung und Verarbeitung von Ereignissen an der Augenoberfläche ein. Es ist ja auch eine Erfahrung des täglichen Lebens, dass das´Nervenkostüm´ bei jedem Menschen durchaus etwas unterschiedlich sein kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c70/1509125946502/OSCB-GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2820cm-72dpi%29_33-10fps+GIF.gif FAKTEN über das TROCKENE AUGE Diese schematische Animation des LIDSCHLAGES illustriert die prinzipielle Funktion der Augenlider zur Verteilung der Tränen in einen dünnen Film im Bereich der Lidspalte um das Gewebe der Augenoberfläche dort auch bei geöffnetem Auge feucht zu halten. Eigentliche Tränentropfen treten im Bereich der Lidspalte allerdings nur bei verstärktem Tränenfluss auf. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c87/1509125946519/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8a2d3798e5b41fce2efeef/1580331818957/SCHIRMER-Test%2C+Tr%C3%A4nen%2C+Trockenes+Auge%2C+Sicca%2C+Tears%2C+Tear+Film+Dry+Eye+Disease_Ohne+Text+mit+STREIFEN_20_%28c%29+ENK%2C+www.OSCB-Berlin.org__.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c7c/1533151076135/ FAKTEN über das TROCKENE AUGE Die animierte schematische Zeichnung, zeigt einen sehr instabilem Tränenfilm. Hier bleibt er nach einem Lidschlag nur für etwa eine einzige Sekunde stabil ehe er aufbricht. Dies weist auf eine starke Störung des Systems hin und lässt nachfolgende Gewebeschädigung vermuten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d88f9978405b92157f7e956/1580331818943/OSCB-Berlin.org_%28c%29-ENK--Erich-and-Nadja-Knop_AUGENOBERFL%C3%84CHE-%26-TR%C3%84NEN%2C-ANIMATION-NEU_20-8-2_.gif FAKTEN über das TROCKENE AUGE In der Zeichnung ist die Tiefe des Konjunktivalsackes und die Dicke des Tränenfilms übertrieben gross dargestellt, damit man sie sehen kann - tatsächlich liegen die Lider praktisch direkt auf dem Augapfel, der Bindehaut-Sack bildet nur einen feuchten Spaltraum, und der Tränenfilm ist äusserst dünn. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6207131ae6cfa7d707f28c/1567176570850/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___TYPISCHE+BEFUNDE+des+TROCKENEN+AUGES_20_.jpg FAKTEN über das TROCKENE AUGE Ein mäßiges Trockenes Auge zeigt typischerweise nur eine leichte Rötung der Bindehaut- und gegebenenfalls der Lidränder. Die Öffnungen der Meibomschen Talgdrüsen werden oft durch sichtbares oder unsichtbares verdicktes Sekret verstopft - dies ist die häufigste Hauptursache des Trockenen Auges. Oberflächendefekte erscheinen in der Vitalfärbung mit Fluoreszein als Keratitis superficialis punctata (KSP). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae0bc9c0e2e72ad6f9f6c89/1509125946521/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56a2d1d8f7650001917260/1567176570797/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg FAKTEN über das TROCKENE AUGE => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5d94ed349fbb27252bd68b91/1580331824510/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Ocular+Surface%2C+Tearfilm%2C+Tr%C3%A4nenfilm+Augenoberfl%C3%A4che_Feinstruktur+von+Augenoberfl%C3%A4che+und+Tr%C3%A4nenfilm%2C+Neuer_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - ZELLEN der Oberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5babae7fec212dee2551c2cb/1567176570836/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - RISIKOFAKTOREN für das Trockene Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5b392df46d2a7342d2e4c812/1567176570832/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___SYMPTOMS+in+Dry+Eye+Disease_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - SYMPTOME beim Trockenen Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5aeeede2aa4a9972fb2705d7/1567176570828/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - PATHOGENESE des Trockenen Auges https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5aeee56d1ae6cf459ee25db8/1567176570825/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - KLINISCHE ZEICHEN des Trockenen Auges https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5aeee40c1ae6cf459ee2442e/1567176570821/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - Die Augen-LIDER https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5aeee366aa4a9972fb264ed7/1567176570819/TR%C3%84NENFILM-%28-und-Augenoberfl%C3%A4che%29__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2.gif FAKTEN über das TROCKENE AUGE - Tränen-FILM auf der Augenoberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5aeee2150e2e72598b3f1192/1567176570816/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif FAKTEN über das TROCKENE AUGE - TRÄNENFLUSS über die Augenoberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5ae5df6570a6adc5612634b9/1567176570812/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif FAKTEN über das TROCKENE AUGE - CHRONISCHE VERSCHLIMMERUNG des Trockenen Auges https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5ae5dee76d2a739e98d0c463/1567176570809/OSCB-Berlin.org_Augenoberfl%C3%A4che-%E2%80%93-Nervensystem-%E2%80%93-Gef%C3%BChl-%E2%80%93-SCHMERZ.gif FAKTEN über das TROCKENE AUGE - SCHMERZ-Syndrome https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae5ddfb575d1fd630deb04f/5ae5ddfc1ae6cfa83d4c391b/1567176570804/OSCB-Berlin.org_DIE+AUGENOBERFL%C3%84CHE.png FAKTEN über das TROCKENE AUGE - Die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b61fdfa758d4635edaf05fb/1567176570847/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME_Kennen-Sie-das-auch_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedd87703ce64705647d02b/1567176570839/TR%C3%84NENFILM-%28-und-Augenoberfl%C3%A4che%29__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2.gif FAKTEN über das TROCKENE AUGE Der TRÄNENFILM (links) besteht aus 3 Schichten, deren Bestandteile von 3 verschiedenen Arten von Augen-DRÜSEN (rechts) produziert werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b01a006562fa7b754d3d72e/1567176469803/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L-MANGEL+ist+die+h%C3%A4ufigste+Ursache+f%C3%BCr+ein+Trockenes+Auge_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6d6c11426fc000016e02d9/1580329301575/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d77976f4daeac2b97975469/1580329301613/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_EINMAL+KONTAKTLINSEN%2C+TAGESLINSEN_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c2aaf2a575d1f0c31886170/1567176469785/OSCB-Berlin.org%2C+%28c%29+ENK_Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_Neu_30_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d70081344bf6400013b4c02/1595497681895/ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_Tear-Film-DRY-SPOT-%2B-Light-SCATTERING_%2B-OSCB_ZUGESCHNITTEN_NEU-mit-ZETTEL-NUR-CORNEA_15-11-0%2C7_.gif FAKTEN über das TROCKENE AUGE Entwicklung einer Lücke im Tränenfilm (engl.: ´Dry Spot´) bei Tränenfilm-Mangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d775a2437a52f73f2711640/1580329301592/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che+und+KONTAKTLINSE_20+OHNE+Text_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4eca55aaee5b6fc5d6f5fa/1596741310947/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2C%2BSQUAMOUS%2BMETAPLASIA_Trockenes%2BAuge%2C%2BPLATTENEPITHEL%2BMETAPLASIE%2B%28LM%2BSEM%29_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6e3959b91b0c0001096cc2/1580329301561/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740dd7/1521226543182/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_600pix-8-2%2C5.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d86199f68af882378150079/1580329301578/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye+Disease%2C+Trockenes+Auge_Meibomdr%C3%BCsen+Dysfunktion+%28MDD%2C+MGD%29+mit+verstopften+und+irregul%C3%A4ren+%C3%96ffnungen+eingedicktes+Sekret+wird+ausgepresst_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5ca01e6ac3802906ddc5d6/1599905833099/OSCB-Berlin.org_%28c%29+ENK_GIF-ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_%28GEK%C3%9CRZT-4_400-11-0%2C7%29.gif FAKTEN über das TROCKENE AUGE Wenn das Tränenwasser verdunstet (blaue gewellte Pfeile), bleiben die Salze und Proteine (graue Kreise in der Flüssigkeit) zurück und verursachen eine konzentriertere "salzige" Zusammensetzung der verbleibenden Tränen, die als "Hyperosmolarität" bezeichnet wird. Hyperosmolarität, ähnlich wie erhöhte mechanische Reibung, reizt das Augengewebe und die Zellen. Dies führt bei der Erkrankung des trockenen Auges zu Schäden und Entzündungen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740dcf/1526802388733/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4eadd8b8a71075e832c716/1596741310937/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_HARD+vs.+SOFT+Contact+Lenses%2C+WEICHE+Flexible+Hydrogel++VS.++HARTE+Kontaktlinsen+auf+FINGER_%C3%9CBEReinander_10_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7cf9ba5d3acf3cc545bb99/1580329301580/OSCB-GIF_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT-_20-72_2-1fps_%C3%9CBERARBEITET-%2B-GELBER-ZETTEL%2C-20-3-1%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f15c13d71e8e22a7e2f7ec9/1596741310885/Tr%C3%A4nentropfen%2C+dunkler+mit+Partikeln+2_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7757843d27287f52cf792a/1580329301589/OSCB-Berlin.org_%28c%29ENK_Trockenes+Auge%2C+Dry+Eye+Disease%2C+Contact+Lens%2C+Kontaktlinse_OPTISCHE+VORTEILE+der+Kontaktlinse_OHNE+Text_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f36a2bdc095bb4219401f07/1597416139712/OSCB-Berlin.org_Einige-THERAPIE-Optionen--bei--Meibomdr%C3%BCsen-Dysfunktion-%28MDD%29_Lipid-Substitution-%2B-Physikalische-Therapie_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb38b5c652dea06466d548d/1567176469787/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d76a640e1c47672b2f740fb/1580329301610/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__600-4-0%2C3.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6fe9c76ee6740001961a1a/1580329301586/OSCB-Berlin.org%2C+%28c%29+ENK_Sex+Hormones%2C+GESCHLECHTS+HORMONE_10+LINK+BILDCHEN_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e381cdbcd5a0d4354260ad3/1596741310889/OSCB-Berlin.org-%28c%29_Animation-BLINZELN-BLINK-%28QUER%2BFRONTAL%29_1-7_TR%C3%84NENFLUSS%2BABFLUSS%2BDRAINAGE_10-25-0%2C2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d861b0747101b6c869232ec/1595429739906/OSCB-GIF_MEIBOM-SECRETION-%2B-DELIVERY_aus-Folien-zur-ANIMATION-etc.-aus-WAKAYAMA-%2B-ISER-2016_HEINRICH-MEIBOM-%28BESSER%29_NEU_KURZ-15-4-0%2C4.gif FAKTEN über das TROCKENE AUGE Der Lidschlag sorgt für die Auspressung der Meibomdrüsen: Die Meibomdrüsen bilden das Öl durch Haufen von Drüsenzellen in rundlichen Endstücken (”Secretion” links unten in der Abbildung). Die Drüsenzellen liegen tief im Augenlid und füllen das Gangsystem der Drüsen mit öligem Sekret (Pfeile). Durch den leichten Druck der Lidmuskulatur beim Lidschlag werden Öl-Tröpfchen aus der Drüsen-Öffnung am Lidrand herausgedrückt (“Delivery”). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d769edec12d52021cbc4440/1580329301606/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_MIKROBEN-auf-Kontaktlinsen-k%C3%B6nnen-sich-verstecken-in-protektiven-BIOFILMEN.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d88fa08c0fd7d385a3dbc22/1580329301552/OSCB-Berlin.org_%28c%29-ENK--Erich-and-Nadja-Knop_AUGENOBERFL%C3%84CHE-%26-TR%C3%84NEN%2C-ANIMATION-NEU_20-8-2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d76a8f7b71aa13d0627a9a3/1580329301598/OSCB-Berlin.org_KONTAKTLINSEN---Anpassung-und-Typen_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df3eebd3aeec95f9e99ca5d/1580329301573/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56a2405638d800016dcf6a/1567700221662/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg FAKTEN über das TROCKENE AUGE => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b019e5270a6ada6e23bf6fa/1567176469798/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e381e660bbd9407606609ca/1596741310880/OSCB-Berlin.org-%28c%29-ENK_ANIMATION_Der-Beitrag-der-Augenoberfl%C3%A4che-zur-ANATOMIE-%2B-Funktion-des-AUGES__15-5-2_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d778e123d27287f52d27554/1580329301595/OSCB-Berlin.org_Sklerale-Kontaktlinsen-reichen-bis-weit-in-den-Fornix_ALS+JPG+OHNE+Text+20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae76728aa4a9919289b4070/1567176469807/ARZT-Symbol+%28GR%C3%9CN%29_%C3%9Cberarbeitet+3R+KLEIN.png FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d97303f735404860574e5/5f3175a0b649e26bac77e6db/1597077047113/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_20_.jpg FAKTEN über das TROCKENE AUGE - TROCKENHEIT und KL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d97303f735404860574e5/5e4d99a9a5eeda76f6039a44/1596741310931/OSCB-Berlin.org_%28c%29ENK_Trockenes%2BAuge%2C%2BDry%2BEye%2BDisease%2C%2BContact%2BLens%2C%2BKontaktlinse_OPTISCHE%2BVORTEILE%2Bder%2BKontaktlinse_OHNE%2BText_10_Florence+MALET_.jpg FAKTEN über das TROCKENE AUGE - BRILLE AUF DEM AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d97303f735404860574e5/5e4d974f3f73540486058335/1596741310927/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__10-4-0%2C3-KLEIN-LINK-ANIMATION%2B%281%29.gif FAKTEN über das TROCKENE AUGE - HYGIENE .. muss schon sein ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d97303f735404860574e5/5e4d9741ee5bb23bd7176c82/1596741310921/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Contact%2BLenses%2C%2Bfiting%2Band%2Bcontrol_Kontaktlinsen%2C%2BANPASSUNG%2Bund%2BNACHKONTROLLE_10%2BLINK%2BBILDCHEN_+%281%29.jpg FAKTEN über das TROCKENE AUGE - PASST &amp; SITZT ... Kontrolle ist besser ;-) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d97303f735404860574e5/5e4d9731ad89174386a37fb1/1596741310914/OSCB-GIF_KL%2BWeich_OSCB%2BTEXT_LIDER%2B%28FRONTAL%29%2BANIMATION%2BBLINZELN_%2B%2B%2BKONTAKTLINSE%2BWEICHE%2BCorneoscleral%2BFESTER%2B%2880-72%29_8-12-0%2C2%2BGIF%2B2x8Bit_NEU-9-19_KLEIN-LINK-ANIMATION_%2B%281%29.gif FAKTEN über das TROCKENE AUGE - KONTAKTLINSEN SCHWIMMEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4ebdd4343beb582c02ff98/1596741310942/OSCB-GIF_Augenoberfl%C3%A4che-ANIMATION_Blinzeln-%2B-AUGENBEWEGUNG-%2BKONTAKTLINSE-%2B-TEXT_%288%2C11-1.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740de3/1522604667877/OSCB-Berlin.org_HYGIENE-ist-ein-ENTSCHEIDENDER-FAKTOR-beim-KONTAKTLINSEN-TRAGEN_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740dd9/1522577510201/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedd74a88251b5dc43a5145/1567176469793/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f317167add720323a811665/1597075831585/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_20_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d909520f81c5b0c171952fe/1580329301583/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Risikofaktoren++ALTER+u.+Chronische+Erkankung_10+LINK+BILDCHEN+OHNE+Text_.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6d6a59b91b0c0001f94ef1/1580329301555/OSCB-Berlin.org%2C+%28c%29+ENK_Augenoberfl%C3%A4che+mit+Meibomdr%C3%BCsen+%2B+%C3%96l-Tropfen+%28Schema+auf+Foto%29+_20_.jpg FAKTEN über das TROCKENE AUGE Die Meibomdrüsen in den Augenlidern produzieren Öl für den Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740dcd/1522690237658/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d9250a8aaa2743fa92fde/5e4d92e4c5f027398cc9db0d/1596741310904/OSCB-Berlin.org%2B%28c%29-ENK_Physical%2BTherapy%2B-%2BLID%2BMASSAGE_10_.jpg FAKTEN über das TROCKENE AUGE - Lid MASSAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d9250a8aaa2743fa92fde/5e4d9314fb915040f50b7df0/1596741310908/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_%2B%281%29.gif FAKTEN über das TROCKENE AUGE - Lidrand HYGIENE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d9250a8aaa2743fa92fde/5e4d927c6d9f2254fac322d6/1596741310899/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_%2B%281%29.gif FAKTEN über das TROCKENE AUGE - AugenLid WÄRMUNG https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e4d9250a8aaa2743fa92fde/5e4d925120c08f54b94817ff/1596741310894/OSCB-Berlin.org%2B%28c%29-ENK_TEAR%2BSUBSTITUES%2C%2BTR%C3%84NENERSATZMITTEL%2C%2BSchemabild_10%2BLINK%2BBILDCHEN_.jpg FAKTEN über das TROCKENE AUGE - TRÄNENERSATZMITTEL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740ddd/1509125946475/ FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b012a548a922d8cabfbeaa0/1567176469796/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d769cb09c439646f305c58f/1580329301601/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Chronisch-Mechanische-Irritation-Epithelzellver%C3%A4nderungen-%28Plattenepithel-Metaplasie%29-der-Bulb%C3%A4ren-Konjunktiva.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5ae1d4481ae6cf941a740dc0/1568474883453/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg FAKTEN über das TROCKENE AUGE - Das AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5ae1d4481ae6cf941a740dbe/1569258391609/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg FAKTEN über das TROCKENE AUGE - TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5ae5b3ea8a922de46794d233/1595435476393/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg FAKTEN über das TROCKENE AUGE - THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5ae5a772aa4a99e142fe018e/1567176469774/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2+LINK+BILDCHEN.jpg FAKTEN über das TROCKENE AUGE - Lidrandtherapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5ae75879562fa7d975e51cf9/1567176469781/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg FAKTEN über das TROCKENE AUGE - Der Tränen-FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7a9fd3e29fe74120feeeec/1595435189625/OSCB-GIF_KL%2BWeich_OSCB%2BTEXT_LIDER%2B%28FRONTAL%29%2BANIMATION%2BBLINZELN_%2B%2B%2BKONTAKTLINSE%2BWEICHE%2BCorneoscleral%2BFESTER%2B%2880-72%29_8-12-0%2C2%2BGIF%2B2x8Bit_NEU-9-19_KLEIN-LINK-ANIMATION_.gif FAKTEN über das TROCKENE AUGE - KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7d03632d2bcf38405c064a/1595435557758/ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_Tear-Film-DRY-SPOT-%2B-Light-SCATTERING_%2B-OSCB_ZUGESCHNITTEN_NEU-mit-ZETTEL-NUR-CORNEA_8-11-0%2C7_.gif FAKTEN über das TROCKENE AUGE - Trockene Stellen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7d09a82d2bcf38405c890e/1580329301541/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_.gif FAKTEN über das TROCKENE AUGE - Lid Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7d0dfb78e10150b4effd6a/1580329301544/OSCB-GIF%2BFUNCTIONAL%2BUNIT%2B7%2C%2BBLINZELN%2BNEU%2B3x%2BLANGS%2C%2BNUR%2BBlinzeln%2B%2BLANGE%2Bauf%2Bmit%2BTr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP%2B-%2BGUT_8-22-0%2C15_.gif FAKTEN über das TROCKENE AUGE - Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7d014578e10150b4eee986/1595434791532/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_10-2-07_.gif FAKTEN über das TROCKENE AUGE - Tränen &amp; Drüsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5d7d04e55f172734865e9516/1595435748118/OSCB-GIF_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT-_20-72_2-1fps_%C3%9CBERARBEITET-%2B-GELBER-ZETTEL_10-3-1%2C5_.gif FAKTEN über das TROCKENE AUGE - Öl-Mangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5dd8373dae846337fb5785ad/1595435189399/OSCB-Berlin.org%2C+%28c%29+ENK_RISIKO-Faktoren_Neu+Kombi_.jpg FAKTEN über das TROCKENE AUGE - Risiko-Faktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ae1d4481ae6cf941a740db6/5f1868eaed25093d1b6a9f20/1596741310873/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_.gif FAKTEN über das TROCKENE AUGE - Meibomdrüsen Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740de1/1522603447450/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5631ff70a6ad58609ecc07/1567176469770/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae1d4481ae6cf941a740dc9/1509125946463/OSCB-Berlin.org_Nur-eine-FEUCHTE-Hornhaut-ist-TRANSPARENT_WEB_.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6ff69cfc51c60001649d6c/1580329301564/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-3D-%C3%96L-RUND_+%281%29.gif FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5467f688251b47551180fa/1532258297172/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b536c3f562fa73754d7e508/1532193858191/1_OSCB-Berlin.org_%28c%29ENK_FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b546ae82b6a280bded38c76/1532259373795/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b54ed4970a6ad6dfd019335/1532292433923/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5c21b46d2a73ec3dfc9aab/1532764602098/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg FAKTEN über das TROCKENE AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0c50585713c260c038bfd7/1594642523063/MEHR+INFORMATIONEN+-+BANNER+BILD+Augenoberfl%C3%A4che+%28Bildschirmkopie%29.jpg FAKTEN über das TROCKENE AUGE https://oscb-berlin.org/e-facts-index daily 0.75 2020-11-25 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5ac15b8c6f7b95c073/5e2f0f5ac15b8c6f7b95c074/1580143025750/Tr%C3%A4nendes+Auge_20_Link-Bildchen.jpg More INFO - ENGLISH - The WET Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5ac15b8c6f7b95c073/5e2f0f5ac15b8c6f7b95c078/1580143074140/Das+Trockene+Auge+ist+eine+VERZWICKTE+Erkrankung_20+Link+Bildchen.jpg More INFO - ENGLISH - A TRICKY Condition https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5ac15b8c6f7b95c073/5e2f37313893fc702c797c19/1580152768048/OSCB-Berlin.org---%28c%29-ENK_Kennen+Sie+das+auch%2C+Do+you+also+suffer+%2B+Gelber+Zettel_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - The DRY Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5ac15b8c6f7b95c073/5e3095c365108c5713584d1c/1580242419515/OSCB-Berlin.org---%28c%29-ENK_LIDRAND+IMG_0287+RET+%2B+Gelber+Zettel_10+LINK+BILDCHEN+heller_.jpg More INFO - ENGLISH - The EYELIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e38042a3e87613dac1cdd70/1580729396670/OSCB-Bild_6-Dry+Eye_Lid+and+Blinking+Deficiency+%28LBD%29_ECTROPION%2C+FRONTAL+%2B+TEMPORAL_ohne+Text_10_.jpg More INFO - ENGLISH Protruding lower eyelid with curl of the lid edge outwards (ectropion) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3804552eda9752716a7776/1580729442959/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye+Disease%2C+Trockenes+Auge_OSCB-Bild_6-Dry+Eye_Lid+and+Blinking+Deficiency+%28LBD%29_ENTROPION_15+-+OHNE+Text_.jpg More INFO - ENGLISH Rolling the edge of the lid inwards (entropion) with rubbing of the eyelashes on the eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f1412871a582cf4afcc65/1580143656672/GIF-Animation_%28c%29-OSCB-Berlin.org_TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_Crop-300-23-2%2C5_.gif More INFO - ENGLISH . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f0f5ac15b8c6f7b95c06c/1567176420519/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e38054b74e5c52b9d7525c7/1580729695803/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_DRY-EYE-DISEASE-can-be-TRICKY-Condition_15_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f2cf7bf10fb4a2fe58fe9/1580150097592/FAKTEN+FACTS+Banner%2C+LINK+BILDCHEN.jpg More INFO - ENGLISH => BACK to PAGE selection for FACTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f197280ada7604d24c34d44/1595503329867/OSCB-Berlin.org+%28c%29+ENK_Tear+Film+INHOMOGENEITY+prevents+perfect+visual+Acuity_10_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5bc15b8c6f7b95c105/5e2f0f5bc15b8c6f7b95c10b/1580334807978/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg More INFO - ENGLISH - The ´ DOCTORS´s Page´ is more clinical https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5bc15b8c6f7b95c105/5e2f0f5bc15b8c6f7b95c109/1580334751521/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg More INFO - ENGLISH - The ´PATIENT´s Page´ will not dig too deep https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e2f0f5bc15b8c6f7b95c105/5e2f0f5bc15b8c6f7b95c10e/1580334886877/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg More INFO - ENGLISH - The ´SCIENTIST´s Page´ is open to those with deeper interest https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3803ff8d7df649e7da0a07/1580729356072/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye_10_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f1810f40d2c1a77415d49ef/1595412734218/OSCB-Berlin.org_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%28aus-KL-Weich%29_VERKL.-25br-x-25cm-%2BNEU-MAN_Zettel-10-10-0%2C2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae59b0a6d2a739e98ca6c9f/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d667cbb7d68a50001e93647/1567175966926/FAKTEN_Kapitel+%C3%9Cbersicht_Link+Bildchen_20_.jpg More INFO - ENGLISH => BACK to the MENU of FACTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae59b0a6d2a739e98ca6ca1/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae5a18b03ce64d372d0e606/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg More INFO - ENGLISH The START of a great JOURNEY ... with friends https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae59b0a6d2a739e98ca6c9d/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5cbd0f562fa73ce9374842/5b5cbf062b6a2840031a5cc0/1534277508832/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg More INFO - ENGLISH - Deeper INSIGHT<br>Glossary for the scientific background https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5cbd0f562fa73ce9374842/5b5cbd7970a6addd33b99385/1534277479867/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg More INFO - ENGLISH - OVERVIEW<br>Some more clinical detail https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5cbd0f562fa73ce9374842/5b5cbd101ae6cf8485231f9a/1534277454136/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg More INFO - ENGLISH - Quick GLIMPSE<br> Some things of interest https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae59b0a6d2a739e98ca6c9b/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade81/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5b8f8bf950b7beae313e80/1532882169364/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_4+mit+%C3%96L-Schicht.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade71/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5aedeea303ce6470564a620f/1525631117993/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg More INFO - ENGLISH - The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5ae5b533758d46d77f00a8ec/1526917165245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg More INFO - ENGLISH - TREATMENT of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5adc7846758d46f994cade62/1525003619062/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg More INFO - ENGLISH - EYELID THERAPY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5adc7846758d46f994cade5c/1525003540262/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg More INFO - ENGLISH - CONTACT LENSES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5adc7846758d46f994cade5e/1525003517317/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg More INFO - ENGLISH - DRY EYE DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc7846758d46f994cade59/5adc7846758d46f994cade5a/1525003500006/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg More INFO - ENGLISH - The OCULAR SURFACE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b01ca0270a6ada6e24185a6/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade7d/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade69/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade7f/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade67/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedec76758d46898c354112/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade73/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade6b/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5cc3a7aa4a99bb716291dc/1532882169362/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade7b/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade87/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aeded9d1ae6cf459eccf360/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade6f/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b01c961575d1f8e6e2218ea/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade85/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc7846758d46f994cade77/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aff1a466d2a73441ec76b20/1530301710913/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg More INFO - 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ENGLISH - CAUSATIVE Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332b6/1580767060942/GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_10-12-1%2C5-NEU%2BSchatten-OPT_.gif More INFO - ENGLISH - BASIC FUNCTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332b4/1580767435885/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_TearfIlm+Deficiency+Tr%C3%A4nenfilm+Mangel%2C+PATHOPHYSIOLOGIE+-++PFEILE+_10_DEW271_.jpg More INFO - ENGLISH - Tear Film DEFICIENCY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332b2/1580767421247/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+TEXT_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - SEVERITY Grades https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332b0/1580767489508/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+GRAD+10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - Staggered THERAPY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332ad/1580767392102/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_3_.jpg More INFO - ENGLISH - DIAGNOSTICS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332ab/1580767356445/OSCB-Berlin.org_Klinische%252BBEFUNDE%252Bbeim%252BTrockenen%252BAuge.jpg More INFO - ENGLISH - Main FINDINGS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332a9/1580767371926/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif More INFO - ENGLISH - Main SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332a7/1580767288145/OSCB-GIF_DEWS-II._PPT-VORLAGEN_-20%25-KOPIE%2B10hoch_4-Basteln_VICIOUS-CIRCLE-GLAND-DYSFUNCTION_9-19_360-5-0%2C7_.gif More INFO - ENGLISH - Vicious CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332a5/1580767261484/OSCB-Berlin.org%2C+%28c%29+ENK_Ocular+Surface+%26+Dry+Eye_Augenoberfl%C3%A4che+%26+Trockenes+Auge_EINFLUSSFAKTOREN%2C+RISK+FACTORS_10+LINK+BILDCHEN_JPG6_.jpg More INFO - ENGLISH - INFLUENCE Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332a3/1580767200664/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_SEKUND%C3%84RE+pathogenetische+Faktoren+GEWEBESCHADEN+DEW238_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - TISSUE Damage https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be6332a1/1580767106911/Prim%C3%A4re+PATHOLOGIE%2C+TR%C3%84NENMANGEL+ist+meist+ZUERST+und+GEWEBESCHADEN+nachfolgend_Neu+DEW236_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - Primary PATHOLOGY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f14e7e9fa951be63329b/5e31f14e7e9fa951be63329f/1580767243958/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_jpg6_10_LINK+BILDCHEN_START2_.jpg More INFO - ENGLISH - RISK Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f14e7e9fa951be633307/1569408359473/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019+%2B+TEXT_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f14e7e9fa951be6332fe/1569333768321/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_3_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f14e7e9fa951be6332f2/1509125946490/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f14e7e9fa951be6332ef/1567176507741/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab700/1509125946521/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6eb/1576268443898/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM_NUR-BLINZELN-9-19_500-16-1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab68c/1567176570800/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3a8e8d5657b711db02585c/1580929693511/OSCB-Berlin.org+%28c%29+ENK+_FINE+STRUCTURE+of+the+OCULAR+SURFACE+and+TEAR+FILM_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6e2/1569336642394/SCHIRMER-Test%2C+Tr%C3%A4nen%2C+Trockenes+Auge%2C+Sicca%2C+Tears%2C+Tear+Film+Dry+Eye+Disease_Ohne+Text+mit+STREIFEN_20_%28c%29+ENK%2C+www.OSCB-Berlin.org__.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b03a63ac8e451d6e895f4/1580929693514/OSCB-Berlin.org-%28c%29_Animation-BLINZELN-BLINK-%28QUER%2BFRONTAL%29_1-7_TR%C3%84NENFLUSS%2BABFLUSS%2BDRAINAGE_10-25-0%2C2_.gif More INFO - ENGLISH This schematic simplified animation of the blink movement of the eyelids illustrates the basic function of the eyelids to distribute the tears into a thin film in the area of the eyelid cleft. This allows to keep the tissue of the ocular surface moist even when the lids are open to see. However, actual tear drops (as simplified here) occur in the area of the eyelid cleft only with excessive tear flow. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3af775c8261f7ac1c575eb/1580929693505/OSCB-BErlin.org+%28c%29+ENK_TEAR-FILM+and+Ocular+Surface_Augenoberfl%C3%A4che_GANZ-KURZNEU-3_20+OT.jpg More INFO - ENGLISH The TEAR FILM (left) consists of 3 layers, the components of which are produced by 3 different types of eye glands (right). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6c4/1570042867286/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Die-Augen-Bindehaut-Konjunktiva-hat-eine-empfindliche-Oberfl%C3%A4chenstruktur%2C-Epithel-mit-Becherzellen%2C-Mikrovilli-und-Glykokalyx-%28Koloriertes-LM-%2B-TEM_ALS+JPG_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6df/1567176570850/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___TYPISCHE+BEFUNDE+des+TROCKENEN+AUGES_20_.jpg More INFO - ENGLISH A moderate dry eye typically shows only a slight reddening of the conjunctiva and possibly the edges of the eyelids. The openings of the Meibomian sebaceous glands are often blocked by visible or invisible thickened secretion - this is the most common main cause of the dry eye. Surface defects appear in vital staining with fluorescein as superficial punctate keratitis (KSP). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6ee/1569075050270/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b0e13bc2b3858c2e6751d/1580929693526/Do-you-also-suffer_unstable-fluctuating-blurrred-vision_Animation__www.OSCB-Berlin_10-4-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab703/1567176570854/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3aeb56389a4637b7cb6372/1580929693493/OSCB-Berlin.org-%28c%29-ENK__OCULAR-SURFACE-Augenoberfl%C3%A4che-FOTO-AUGE-QUER--LABNOTES_ENGLISCH_10-9-2_.gif More INFO - ENGLISH In this drawing, the depth of is conjunctival and the thickness of the tear film is exaggerated, so you can see them - in fact, the eyelids are literally right on the eyeball, the conjunctival sac forms only a wet gap, and the tear film is extremely thin. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3aefbcfb8df43f9b29f00e/1580929693499/OSCB-Berlin.org-%28c%29-ENK_Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit__15-2-1_.gif More INFO - ENGLISH The continuous flow of tears over the surface of the eye , which is of the utmost importance for your health, goes (from left to right in the illustration): (1) from the main production site in the lacrimal gland via (2) the visible cornea / cornea and conjunctiva / conjunctiva that must be constantly bathed in (3) the lacrimal drainage system , the ' used to derive' tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab706/1509125946524/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3aea531dd2df314c5635d4/1580929693489/OSCB-Berlin.org+%28c%29+ENK_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu%2B+SECRETION-BATHING-DRAINAGE%2C+Heller%2B%28Simple%29+NEU_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3af54b92dae41f9bf0e2dd/1580929693502/OSCB-Berlin.org_%28c%29+ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM%2Bohne%2BText_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3aff5892dae41f9bf3b92b/1580929693508/OSCB-Berlin.org-%28c%29-ENK_Dry-Eye-Trockenes-Auge%2C-TEAR%2BFILM%2C-Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-600-9-0%2C5.gif More INFO - ENGLISH A LOOK INTO THE TEAR FILM: The middle main part of the tear film in front of the transparent cornea consists of aqueous liquid. The numerous finger-like extensions (micovilli) of the superficial epithelial cells are visible below - they bind the water to the cell surface. The water is bound by the long sugar chains (here reddish) of mucins. Membrane-bound mucins (glykokalyx) are fixed to the microvilli whereas soluble mucins float in the tear film and transform the water into a low-viscosity water-mucin gel. At the top, the tear film is covered by the very thin layer of oil from the fats of the meibomian glands - this prevents the tear water from evaporating too quickly. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b0d4165c5eb6706d3ba3e/1580929693520/OSCB-Berlin.org-%28c%29-ENK_ANIMATION_OIL-DEFICIENCY-and-EVAPORATION-etc_ENGLISCH_KLEIN%2BKURZ_10-36-0%2C8__.gif More INFO - ENGLISH Interestingly, the formation of the oil layer in the tear film is of greater importance than the formation of tear water, because if there is a lack of oil, even abundant tear water evaporates quickly. Gaps are then created in the tear film and the sensitive cells on the surface of the eye are damaged. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b0edfb79ef1475c45d1ea/1580929693523/GIF-Animation_TYPICAL-SYMPTOMS-in-DRY-EYE-DISEASE_Typische-Symptome-beim-Trockenen-Auge_Bild-ENGLISCH-1-4v4_KURZ_10-72_5-1%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6fa/1509125946517/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31ffc59565735041ace33a/1580929693486/FAKTEN+FACTS+Banner%2C+LINK+BILDCHEN.jpg More INFO - ENGLISH => BACK to PAGE selection for FACTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6f1/1569074689988/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6dc/1533151076135/ More INFO - ENGLISH The animated schematic drawing shows a very unstable tear film. Here, after a blink of an eye, it only remains stable for about a second before it opens. This indicates a strong disruption to the system and suggests subsequent tissue damage . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6d0/1567785422986/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+SQUAMOUS+METAPLASIA_Trockenes+Auge%2C+PLATTENEPITHEL+METAPLASIE+%28LM%2BSEM%29_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3aef78b79ef1475c3ca289/1580929693495/OSCB-Berlin.org+%28c%29+ENK%29_3.1.6_Only+a+MOIST+Cornea+can+stay+TRANSPARENT_20+OT_.jpg More INFO - ENGLISH The MOISTURE surface of the eye is needed to the cornea / cornea TRANSPARENT keep https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6e8/1576268152751/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6fd/1509125946519/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6f4/1569074378644/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6e5/1569330809562/OSCB-Berlin.org_Klinische+BEFUNDE+beim+Trockenen+Auge.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f32a5f5edc784a4ab6f7/1509125946516/ More INFO - ENGLISH The neuronal regulation of the surface of the eye, via the cranial nerves V ( trigeminal nerve ) and VII ( facial nerve ) in the brain stem, and also their emotional perception in the brain is complex. It is susceptible to interference, but it can also show certain individual differences between different people. Experiences, evaluations and different types of treatment and processing of events on the surface of the eye are also included here. It is also an experience of everyday life that the ' nerve costume ' can be a little different for every person. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b06d2c8261f7ac1ca2d9e/1580929693517/OSCB-Berlin.org-%28c%29-ENK_ANIMATION_The-Role-of-the-OCULAR-SURACE-in-the-Function-of-the-EYE__15-7-2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab691/1580918587936/OSCB-Berlin.org_Augenoberfl%C3%A4che-%E2%80%93-Nervensystem-%E2%80%93-Gef%C3%BChl-%E2%80%93-SCHMERZ.gif More INFO - ENGLISH - PAIN SYNDROMES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab69c/1580918431744/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - The EYELIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab6a5/1580918758139/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - From DRY EYE to DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab69a/1580918360546/TR%C3%84NENFILM-%28-und-Augenoberfl%C3%A4che%29__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2.gif More INFO - ENGLISH - The TEAR FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab69e/1580918572585/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - CLINICAL SIGNS of Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab6a0/1580918506755/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - PATHOGENESIS of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab6a7/1580918400218/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Ocular+Surface%2C+Tearfilm%2C+Tr%C3%A4nenfilm+Augenoberfl%C3%A4che_Feinstruktur+von+Augenoberfl%C3%A4che+und+Tr%C3%A4nenfilm%2C+Neuer_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - CELLS of the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab697/1580918345235/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif More INFO - ENGLISH - TEAR FLOW along the OCULAR SURFACE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab68f/1580918320176/OSCB-Berlin.org_DIE+AUGENOBERFL%C3%84CHE.png More INFO - ENGLISH - The OCULAR SURFACE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab6a2/1580918529849/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___SYMPTOMS+in+Dry+Eye+Disease_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - SYMPTOMS in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f32a5f5edc784a4ab68e/5e31f32a5f5edc784a4ab693/1580918649683/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif More INFO - ENGLISH - CHRONIC AGGRAVATION in Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3b5/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3d2/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3a4/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif More INFO - ENGLISH The continuous Turnover of Tears at the Ocular Surface goes (1) from their main production in the lacrimal gland over (2) the readily visible cornea and conjunctiva that they must constantly bathe into (3) the lacrimal drainage system that drains the tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3bc/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedec438a922d5e60571d2c/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3ca/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3c4/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3d0/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3ba/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif More INFO - ENGLISH This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3cc/1512819831670/ More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3a2/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5ad3160a88251b90ed40d389/1532637963476/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg More INFO - ENGLISH - PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5ad3160a88251b90ed40d387/1533232663774/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif More INFO - ENGLISH - HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5ad3160a88251b90ed40d391/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png More INFO - ENGLISH - The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5aede0140e2e72598b283040/1525631222034/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif More INFO - ENGLISH - The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5aeee99003ce647056601abf/1533156107801/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - PATHO-MECHANISM of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5aeddec403ce647056488b3f/1525631222031/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - The EYE LIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5aede15c88251b5dc43b786e/1525631222040/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif More INFO - ENGLISH - The Tear FLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5aede569758d46898c346725/1525631222044/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg More INFO - ENGLISH - CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5b63451c88251b6f3e1c9ddf/1533232816579/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad3160a88251b90ed40d386/5b61edf1352f53b920b66434/1533232816574/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif More INFO - ENGLISH - SYMPTOMS of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3c0/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedd9eb88251b5dc43a9ef8/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc75936d2a7395679d5402/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3be/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3c6/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif More INFO - ENGLISH A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that may indicate an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low due to water evaporation and the tissue of the Ocular Surface epithelium has many small defects, that occur as small spots in vital staining with a green stain (fluorescein) observed in blue light. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3c2/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3c8/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d394/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aed8ede88251b31ff7e9520/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif More INFO - ENGLISH A glimpse into the TEAR FILM. The main phase of the Tear Film overlying the transparent cornea is composed of the aqueous fluid from the lacrimal gland. Below are the numerous finger-like protrusions of the surface cells. Their cell bound and and loose secreted mucins (pink filaments) constitute the basal mucin layer that binds the tear water to the ocular cell surface. Mucins mix with the water and together they form a water-mucin gel. The surface of the Tear Film is covered by a very narrow oil layer from the-lipids of the Meibomian glands. The lipid layer has the same thickness and coloring as an oil film on a puddle of water. A main function of the oil layer is to retard the evaporation of the aqueous main phase of the tears. Consequently a lipid deficiency due to a dysfunction of the Meibomian glands is presently reported as the main causative factor for Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3d4/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad3160a88251b90ed40d3ce/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e36d58c2eda975271399919/1580651927589/Do-you-also-suffer_unstable-fluctuating-blurrred-vision_Animation__www.OSCB-Berlin_10-4-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736802/1576325363434/OSCB-Berlin.org+-+%28c%29+ENK_Bildung+von+ABLAGERUNGEN+auf+dem+Lidrand_ANIMATION+-+EINZELBILD+daraus_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e36f6d3e0e43424443ebdc2/1580660447607/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e36cbac6ce96b4a792ee548/1580649398300/GIF-Animation_TYPICAL-SYMPTOMS-in-DRY-EYE-DISEASE_Typische-Symptome-beim-Trockenen-Auge_Bild-ENGLISCH-1-4v4_KURZ_10-72_5-1%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736823/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef27367f6/1529244871746/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2ec03cb5f4e50703f89c39/1582639710007/FAKTEN+FACTS+Banner%2C+LINK+BILDCHEN.jpg More INFO - ENGLISH => BACK to PAGE selection for FACTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736835/1532291687008/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef27367ff/1576320246250/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C+Gewebe+Reizung_NEU_OHNE%2BText_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e36fdc812c5156ca638adb7/1580662230817/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29_Animation-400-2-0%2C9_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef273680b/1567410516894/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e36e4b921662377967f5cb0/1580655818891/GIF_BLINZELN%2C-BLINK-Animation-%28NUR-QUER%29_5-25-0%2C2_.gif More INFO - ENGLISH Schematic representation of the surface of the eye in cross-section. The blink of an eye forms the tear film from the tear fluid . Disorders of the regular blinking of the eye are a typical reason for disorders of the tear film and thus for a dry eye! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef273681a/1569067513354/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg More INFO - ENGLISH The meibomian oil glands in the eyelids usually (left) form oil for the tear film, which inhibits the evaporation of the tear water. If the oil glands are clogged (right), the tear water evaporates quickly and the eye becomes dry. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0c5b366a01a6439a61f8ef/1594645318562/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che%2C+FOTO%2BSCHEMA_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1472d570c97841c3e5a7df/5f1472d87b47154cead529ae/1595176058295/Information-8-TREATMENT_Neu2-ENGLISH_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1472d570c97841c3e5a7df/5f1472d9049f73378ffcce72/1595176035488/Information-7-WORSENING_Neu2-ENGLISH_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1472d570c97841c3e5a7df/5f1472d79e52b071c5a80129/1595175920467/Information-2-COMPLAINTS_Neu2-ENGLISH_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f1472d570c97841c3e5a7df/5f1472d98f488a75b5305c71/1595176019606/Information-6-DAMAGE_Neu2-ENGLISH_.jpg More INFO - 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ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef27367f3/1529244871744/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736826/1576314452930/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736808/1567176374008/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel%2C-%2B-Tr%C3%A4nenfluss%2C-langsam__.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736811/1529869348309/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef273681d/1567502662471/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_+%281%29.gif More INFO - ENGLISH Incomplete blink of an eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef27367fc/1576058807291/OSCB-GIF_3.7_Augenoberfl%C3%A4che-ANIMATION_Blinzeln-%2B-AUGENBEWEGUNG-%2B-TEXT_%2880-72%2C12-2%29_9-19%2C-8-12-0%2C5_-GIF.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef273682f/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef27367f0/1567176374003/Animation_Trockenes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736817/1567176374014/Henrik+SJ%C3%96GREN_Download.jpg More INFO - ENGLISH Henrik SJÖGREN, Swedish ophthalmologist, who was the first to describe the inflammatory disease of the tear and salivary glands named after him, which leads to the Sicca syndrome of the eyes and mouth. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef2736814/1576319439645/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2d81abad322f7ef273682c/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6f309bb8a04537019ef978/1534075112212/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecce/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ece8/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif More INFO - ENGLISH Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecd4/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40eccc/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecd2/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae5dcb8575d1fd630de847d/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aedebca0e2e72598b299398/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ece4/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecd8/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ece6/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5b02ea43562fa79099e82914/1532969295940/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg More INFO - ENGLISH - MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5b02e91a88251b6c02418fc1/1532969296245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg More INFO - ENGLISH - Important RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5ae8a76d0e2e7259c75a5667/1532969308153/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg More INFO - ENGLISH - CONTACT LENSES & Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5adb561c1ae6cfdcd73181e3/1526917722803/OSCB-Bild_6.0_Dry+Eye+Disease_Typical+Symptoms+in+Dry+Eye+Disease+UNstable+or+Blurred+VISION%2C+IRRITATION%2C+PAIN_10.jpg More INFO - ENGLISH - MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5adb52fa70a6ad1da85305ad/1524398222202/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png More INFO - ENGLISH - MAIN CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5ad317b988251b90ed40ecc7/1524395165433/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif More INFO - ENGLISH - CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5ad317b988251b90ed40ecc2/5ad317b988251b90ed40ecc9/1525165516307/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png More INFO - ENGLISH - BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecdc/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif More INFO - ENGLISH Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6f15a41ae6cf931b97577f/1534075112210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecda/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecd6/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ece0/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif More INFO - ENGLISH Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecde/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif More INFO - ENGLISH ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ecd0/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad317b988251b90ed40ece2/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif More INFO - ENGLISH The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adb50b8575d1f52aa809368/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c9c/1567176469798/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e387486558d651b9b4c7ce5/1580758189366/OSCB-Berlin.org%2C-%28c%29-ENK_Lid-margin-HYGIENE_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_Crop-OT_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31fda70bccc414d48add6f/1596189146500/FAKTEN+FACTS+Banner%2C+LINK+BILDCHEN.jpg More INFO - ENGLISH => BACK to PAGE selection for FACTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e384ab97273ab09bb069fee/1580747461945/OSCB-Berlin.org-%28c%29-ENK_Nur-der-d%C3%BCnne-TR%C3%84NENFILM-garantiert-Gesundheit-und-SCHARFES-SEHEN_OT-aus-DT_15-8-1_-.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c46/1567176469770/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c87/1567508024662/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cbf/1522577510201/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cb3/1569756469497/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Risikofaktoren++ALTER+u.+Chronische+Erkankung_10+LINK+BILDCHEN+OHNE+Text_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e38191f2eda9752716cf5eb/1580734767425/OSCB-Berlin.org-%28c%29_Animation-BLINZELN-BLINK-%28QUER%2BFRONTAL%29_1-7_TR%C3%84NENFLUSS%2BABFLUSS%2BDRAINAGE_10-25-0%2C2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ce9/1568118649705/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_EINMAL+KONTAKTLINSEN%2C+TAGESLINSEN_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cc6/1568102289899/OSCB-Berlin.org_%28c%29ENK_Trockenes+Auge%2C+Dry+Eye+Disease%2C+Contact+Lens%2C+Kontaktlinse_OPTISCHE+VORTEILE+der+Kontaktlinse_OHNE+Text_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f1890ef41e2fa5c6513ce17/1595445502708/OSCB-Berlin.org_%2528c%2529ENK_Trockenes-Auge%252C-Dry-Eye-Disease%252C-Contact-Lens%252C-Kontaktlinse__%25C3%2596L-MANGEL%2Bist%2Bdie%2Bh%25C3%25A4ufigste%2BUrsache%2Bf%25C3%25BCr%2Bein%2BTrockenes%2BAuge_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c99/1596189417293/GIF-ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_EINZELBILDER%2C-DEUTSCH_33-10-0%2C8_ORIG-DOPP---OHNE-TEXT_.gif More INFO - ENGLISH When the tear water evaporates (blue wavy arrows), the salts and proteins (grey circles in the liquid) remain and cause a more concentrated "salty" composition of the remaining tears, called "hyperosmolarity". Hyperosmolarity, similar to increased mechanical friction, irritates eye tissue and cells. This leads to damage and inflammation in dry eye disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e332d58f12b1f51b9f70711/5e4d9c3cad89174386a4ea47/1582144635118/OSCB-Berlin.org_%28c%29ENK_Trockenes%2BAuge%2C%2BDry%2BEye%2BDisease%2C%2BContact%2BLens%2C%2BKontaktlinse_OPTISCHE%2BVORTEILE%2Bder%2BKontaktlinse_OHNE%2BText_10_Florence+MALET_.jpg More INFO - ENGLISH - GLASSES on the EYE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e332d58f12b1f51b9f70711/5e36d83f21662377967da3c3/1580652651642/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Contact%2BLenses%2C%2Bfiting%2Band%2Bcontrol_Kontaktlinsen%2C%2BANPASSUNG%2Bund%2BNACHKONTROLLE_10%2BLINK%2BBILDCHEN_.jpg More INFO - ENGLISH - FITTING &amp; Controls https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e332d58f12b1f51b9f70711/5e332ea4aad93854bcb1ab98/1582144737468/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__10-4-0%2C3-KLEIN-LINK-ANIMATION+%281%29.gif More INFO - ENGLISH - HYGIENE ... most CERTAINLY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e332d58f12b1f51b9f70711/5e332d593e07947c1b14ae31/1596711020253/OSCB-GIF_KL%2BWeich_OSCB%2BTEXT_LIDER%2B%28FRONTAL%29%2BANIMATION%2BBLINZELN_%2B%2B%2BKONTAKTLINSE%2BWEICHE%2BCorneoscleral%2BFESTER%2B%2880-72%29_8-12-0%2C2%2BGIF%2B2x8Bit_NEU-9-19_KLEIN-LINK-ANIMATION_+%281%29.gif More INFO - ENGLISH - FLOATING...floating...floating https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c8a/1567176469793/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cae/1567176469796/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3826ac3e87613dac21814d/1580738234377/OSCB-Berlin.org-%28c%29-ENK__BLINZELN-NEU-3x-LANGS%2C-NUR%2BBlinzeln-LANGE-auf-mit-Tr%C3%A4nenFILM_8-25-0%2C15_CROP-GUT_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c75/1567509085431/OSCB-Berlin.org%2C+%28c%29+ENK_Augenoberfl%C3%A4che+mit+Meibomdr%C3%BCsen+%2B+%C3%96l-Tropfen+%28Schema+auf+Foto%29+_20_.jpg More INFO - ENGLISH The meibomian glands in the eyelids produce oil for the tear film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e380c2626acc86be0205684/1580731444053/OSCB-Berlin.org-%28c%29-ENK__OCULAR-SURFACE-Augenoberfl%C3%A4che-FOTO-AUGE-QUER--LABNOTES_ENGLISCH_10-9-2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f15c19471e8e22a7e2f89cd/1595261354118/Tr%C3%A4nentropfen%2C+dunkler+mit+Partikeln+2_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cb6/1567615438355/OSCB-Berlin.org%2C+%28c%29+ENK_Sex+Hormones%2C+GESCHLECHTS+HORMONE_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cd8/1569353621151/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+SQUAMOUS+METAPLASIA_Trockenes+Auge%2C+PLATTENEPITHEL+METAPLASIE+%28LM%2BSEM%29_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e386d3a5a6688749ea72211/1580756334995/OSCB-Berlin.org-%28c%29-ENK_Animation-PHYSICA-THERAPY-WARMING_300-16-1_ENGLISCH_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ca5/1567452194158/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cc9/1568102958263/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che+und+KONTAKTLINSE_20+OHNE+Text_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ce6/1568056924974/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__600-4-0%2C3.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e386ed0d3aefa05b85093db/1580756748187/OSCB-Berlin.org+%28c%29-ENK_TEAR+SUBSTITUES%2C+TR%C3%84NENERSATZMITTEL%2C+Schemabild_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e3337ec75ef5565365d4644/5e3339ca18f0b24c16b0c031/1582142608936/OSCB-Berlin.org+%28c%29-ENK_Physical+Therapy+-+LID+MASSAGE_10_.jpg More INFO - ENGLISH - LID MASSAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e3337ec75ef5565365d4644/5e33382c4c36c6411f6d2bc2/1582142615209/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_+%281%29.gif More INFO - ENGLISH - Lid MARGIN HYGIENE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e3337ec75ef5565365d4644/5e333807b06af95c04ce2dcb/1582142602170/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_+%281%29.gif More INFO - ENGLISH - Eyelid WARMING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e3337ec75ef5565365d4644/5e3337edadfec52f85e3e29b/1580415803834/OSCB-Berlin.org+%28c%29-ENK_TEAR+SUBSTITUES%2C+TR%C3%84NENERSATZMITTEL%2C+Schemabild_10+LINK+BILDCHEN_.jpg More INFO - ENGLISH - TEAR SUPPLEMENTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3817426ce96b4a7963161d/1580734290960/OSCB-BErlin.org+%28c%29+ENK_Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_15_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c93/1595497087897/ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_Tear-Film-DRY-SPOT-%2B-Light-SCATTERING_%2B-OSCB_ZUGESCHNITTEN_NEU-mit-ZETTEL-NUR-CORNEA_15-11-0%2C7_.gif More INFO - ENGLISH Development of a ´dry spot´in the tear film due to tear film deficiency https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cd5/1568054462302/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Chronisch-Mechanische-Irritation-Epithelzellver%C3%A4nderungen-%28Plattenepithel-Metaplasie%29-der-Bulb%C3%A4ren-Konjunktiva.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cab/1568471510676/OSCB-GIF_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT-_20-72_2-1fps_%C3%9CBERARBEITET-%2B-GELBER-ZETTEL%2C-20-3-1%2C5_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3873157cc7a659e4aa1548/1580757795981/OSCB-Berlin.org_Some+THERAPY-Options+in+Meibomian+Gland+Dysfunction+%28MGD%29+Lipid+Substitution+%26+Physical+Therapy_15_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3823556ce96b4a7964d8d2/1595429766427/OSCB-Berlin.org+%28c%29+ENK_Animation_MEIBOMIAN+Gland+OIL+SECRETION%2BDELIVERY__NEU_KURZ-15-4-0%2C4.gif More INFO - ENGLISH The blink of the eyelids ensures that the meibomian glands are squeezed out: the meibomian glands form the oil through piles of glandular cells in rounded end pieces (“secretion” at the bottom left of the figure). The glandular cells lie deep in the eyelid and fill the duct system of the glands with lipid secretum (arrows). The light pressure of the eyelid muscles, upon the blink of the eyelids, pushes oil droplets out of the gland opening at the edge of the eyelid (“Dellivery”). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ccc/1522603447450/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ce3/1568055015336/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_MIKROBEN-auf-Kontaktlinsen-k%C3%B6nnen-sich-verstecken-in-protektiven-BIOFILMEN.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ce0/1522604667877/OSCB-Berlin.org_HYGIENE-ist-ein-ENTSCHEIDENDER-FAKTOR-beim-KONTAKTLINSEN-TRAGEN_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18cd2/1568057601427/OSCB-Berlin.org_KONTAKTLINSEN---Anpassung-und-Typen_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3821a36ce96b4a79649590/1580736946778/OSCB-Berlin.org-%28c%29-ENK_Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit__15-2-1_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18c90/1526802388733/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c57/1580409530256/ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_Tear-Film-DRY-SPOT-%2B-Light-SCATTERING_%2B-OSCB_ZUGESCHNITTEN_NEU-mit-ZETTEL-NUR-CORNEA_8-11-0%2C7_.gif More INFO - ENGLISH - Tear Film BREAK-UP https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c53/1580409727176/OSCB-GIF_KL%2BWeich_OSCB%2BTEXT_LIDER%2B%28FRONTAL%29%2BANIMATION%2BBLINZELN_%2B%2B%2BKONTAKTLINSE%2BWEICHE%2BCorneoscleral%2BFESTER%2B%2880-72%29_8-12-0%2C2%2BGIF%2B2x8Bit_NEU-9-19_KLEIN-LINK-ANIMATION_.gif More INFO - ENGLISH - CONTACT LENSES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c59/1580409550334/OSCB-GIF_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT-_20-72_2-1fps_%C3%9CBERARBEITET-%2B-GELBER-ZETTEL_10-3-1%2C5_.gif More INFO - ENGLISH - OIL DEFICIENCY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c55/1595434890696/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_10-2-07_.gif More INFO - ENGLISH - TEARS &amp; GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c4d/1580409638486/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg More INFO - ENGLISH - Dry Eye THERAPY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c5d/1580409677475/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_.gif More INFO - ENGLISH - EYELID Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c4b/1580409404700/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg More INFO - ENGLISH - OCULAR SURFACE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c49/1580409497697/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg More INFO - ENGLISH - DRY EYE Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c5f/1580409476781/OSCB-GIF%2BFUNCTIONAL%2BUNIT%2B7%2C%2BBLINZELN%2BNEU%2B3x%2BLANGS%2C%2BNUR%2BBlinzeln%2B%2BLANGE%2Bauf%2Bmit%2BTr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP%2B-%2BGUT_8-22-0%2C15_.gif More INFO - ENGLISH - The TEAR FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31e9556db8513a09f18c48/5e31e9556db8513a09f18c63/1580409611291/OSCB-Berlin.org%2C+%28c%29+ENK_RISIKO-Faktoren_Neu+Kombi_.jpg More INFO - ENGLISH - RISK FACTORS 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31e9556db8513a09f18ccf/1568116270949/OSCB-Berlin.org_Sklerale-Kontaktlinsen-reichen-bis-weit-in-den-Fornix_ALS+JPG+OHNE+Text+20_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e38252474e5c52b9d79637f/1580737841112/OSCB-Berlin.org+%28c%29+ENK__Only+a+MOIST+Cornea+can+stay+TRANSPARENT%2C+nur+eine+Feuchte+Hornhaut+kann+Transparant+bleiben_15+OT_.jpg More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e38121aced5384d70e7ec66/1580732965260/OSCB-Berlin.org-%28c%29-ENK_ANIMATION_The-Role-of-the-OCULAR-SURACE-in-the-Function-of-the-EYE__15-7-2_.gif More INFO - ENGLISH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b58b5a6758d46c96f0b0ccf/1533386342932/1_OSCB-Berlin.org_%28c%29ENK_FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg More INFO - ENGLISH 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5f58d71ae6cfe6fa24232f/1532882040104/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa24232a/1533465845768/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_10+LINK+BILDCHEN+jpg6_.jpg Spanish Facts (OLD Text Pages) - y algo MÁS INFORMACIÓN<br>para un mejor<br>entendimiento More INFORMATION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa242328/1533466277251/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - VISIÓN MÁS PROFUNDA<br>... casi un poco<br>Glosario https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa242326/1533466204063/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - VISIÓN COMPLETA<br>... para los más<br>comprensión profunda https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa242324/1533466052012/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - MIRADA RÁPIDA<br>... suficiente de todo<br>ser informado https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa242322/1533465949048/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - EL COMIENZO de<br>un gran VIAJE<br>... con amigos https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5f58d71ae6cfe6fa24231f/5b5f58d71ae6cfe6fa242320/1533466378727/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____AUGE_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - El corto<br>FICHA INFORMATIVA<br>de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5f58d71ae6cfe6fa242331/1532882040106/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0c70a6ad79d5694817/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694839/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694832/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569482a/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694843/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif Spanish Facts (OLD Text Pages) Las lentes de contacto ' rígidas ' son típicamente más pequeñas y se apoyan exclusivamente en la córnea. Necesitan un cierto tiempo de adaptación para el usuario y, por lo tanto, están menos extendidos, pero tienen un material inerte superior y una calidad óptica. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d56948ac/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694837/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569483e/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694921/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif Spanish Facts (OLD Text Pages) La Higiene Insuficiente es un factor crucial en el uso de la Lentes de Contacto y resulta en una mayor tasa de infecciones oculares en usuarios de lentes de contacto . Los microbios pueden ser introducidos por los dedos del usuario o por el uso de agua del grifo, que debe omitirse. Ciertos tipos de microbios también ocurren en la superficie ocular normal. Los microbios crecen en las lentes y en los contenedores de almacenamiento y forman ' biofilms ' adhesivos que los protegen contra la limpieza y la eliminación.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694845/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Spanish Facts (OLD Text Pages) Movimiento de una lente de contacto blanda en la superficie del globo ocular y detrás de los párpados. La lente de contacto se mueve con cada movimiento de la mirada del globo ocular y también con los frecuentes parpadeos. La cantidad de fricción mecánica en la superficie ocular típicamente aumenta en el uso de lentes de contacto, incluso cuando la película lagrimal es suficiente. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d56948ef/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d5694825/1533067077301/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg Spanish Facts (OLD Text Pages) - PRINCIPALES SÍNTOMAS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d5694823/1533067099204/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg Spanish Facts (OLD Text Pages) - FACTORES DE RIESGO IMPORTANTES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d5694821/1533067116646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg Spanish Facts (OLD Text Pages) - LENTES DE CONTACTO y Superficie Ocular https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d569481f/1533067045684/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png Spanish Facts (OLD Text Pages) - PRINCIPALES SIGNOS CLÍNICOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d569481c/1533067027470/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif Spanish Facts (OLD Text Pages) - FACTORES CAUSATIVOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b60be0d70a6ad79d5694819/5b60be0d70a6ad79d569481a/1533067008920/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png Spanish Facts (OLD Text Pages) - FUNCIÓN BÁSICA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569482d/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694841/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif Spanish Facts (OLD Text Pages) Diagrama esquemático de una lente de contacto blanda típica de tamaño medio en el ojo y parcialmente detrás de las tapas. Estas lentes se denominan lentes de contacto corneoesclerales porque llegan a la esclerótica por encima de la córnea . Este es el tipo de lentes de contacto más utilizado. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569483b/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694828/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569487b/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif Spanish Facts (OLD Text Pages) La estructura fina del epitelio superficial puede sufrir un deterioro donde se expone a la influencia de una lente de contacto. Aquí se muestra el cambio del epitelio conjuntival bulbar en la zona de excursión de una lente de contacto blanda. Las células de la superficie cúbica con células caliciformes intercaladas para la producción de mucinas adhesivas al agua son reemplazadas por un epitelio escamoso sin células caliciformes en un proceso denominado " metaplasia escamosa ". https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d569482f/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b60be0d70a6ad79d5694834/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8bc/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8c4/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8a5/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif Spanish Facts (OLD Text Pages) Un vistazo al TEAR FILM. La fase principal de la película lagrimal que recubre la córnea transparente está compuesta por el fluido acuoso de la glándula lagrimal. Debajo están las numerosas protuberancias similares a dedos de las células de la superficie. Sus mucinas secretadas y unidas a células (filamentos rosados) constituyen la capa basal de mucina que une el agua de lágrima a la superficie de la célula ocular. Las mucinas se mezclan con el agua y juntas forman un gel de agua y mucina. La superficie de la película lagrimal está cubierta por una capa de aceite muy estrecha de los lípidos de las glándulas de Meibomio. La capa de lípidos tiene el mismo espesor y coloración que una película de aceite en un charco de agua. Una función principal de la capa de aceite es retardar la evaporación de la fase principal acuosa de las lágrimas. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d89d/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8ae/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8c0/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8a3/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8b4/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif Spanish Facts (OLD Text Pages) Un ojo seco moderado típicamente muestra sólo un leve enrojecimiento de los márgenes de la conjuntiva y la tapa que pueden indicar un estado inflamatorio tal como se describe por el término'Keratoconjunctiv SIIT sicca'. Los orificios de las glándulas sebáceas de Meibomio a menudo están obstruidos por secreciones secretas visibles o invisibles (que representan la causa principal más frecuente de la enfermedad ocular seca). El volumen de lágrimas es bajo debido a la evaporación del agua y el tejido del epitelio de la superficie ocular tiene muchos defectos pequeños, que aparecen como manchas pequeñas en la tinción vital con una mancha verde (fluoresceína) observada en la luz azul. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8ba/1512819831670/ Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d89b/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8b8/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8a9/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d894/1533233726918/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - PATO-MECANISMO de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d898/1533234068663/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - ¿CÓMO OBTENEMOS un Ojo Seco ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d88e/1533233490703/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif Spanish Facts (OLD Text Pages) - La PELÍCULA lagrimal https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d88a/1533233281645/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Spanish Facts (OLD Text Pages) - La SUPERFICIE OCULAR en DETALLE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d886/1533233936589/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg Spanish Facts (OLD Text Pages) - SINDROMES de DOLOR en Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d88c/1533233591830/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - Los PÁRPADOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d888/1533234191834/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Spanish Facts (OLD Text Pages) - ¿ POR QUÉ el ojo seco SERÁ MALO ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d890/1533233457191/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Spanish Facts (OLD Text Pages) - El FLUJO de Lágrima https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d896/1533233772836/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif Spanish Facts (OLD Text Pages) - SÍNTOMAS de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6346b0aa4a99747bd6d885/5b6346b0aa4a99747bd6d892/1533233863107/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg Spanish Facts (OLD Text Pages) - SIGNOS Clínicos https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8b0/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8a1/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8be/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8a7/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Spanish Facts (OLD Text Pages) This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8b6/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8ab/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8b2/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d883/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d8c2/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6346b0aa4a99747bd6d89f/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif Spanish Facts (OLD Text Pages) La rotación continua de lágrimas en la superficie ocular va (1) de su producción principal en la glándula lagrimal sobre (2) la córnea y la conjuntiva fácilmente visibles en las que deben bañarse constantemente (3) el sistema de drenaje lagrimal que drena las lágrimas en el nariz. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5f670870a6ad39403ff206/1532978958698/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5f5e160e2e72a2572fca4f/1532976669881/1_OSCB-Berlin.org_%28c%29ENK_FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg Spanish Facts (OLD Text Pages) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5f5f211ae6cfe6fa25bd5c/1532976932746/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg Spanish Facts (OLD Text Pages) https://oscb-berlin.org/ita-facts-index daily 0.75 2018-08-19 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a2f/1512819831615/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a21/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a3d/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659fdbf950b7f277c56a05/5b659fdbf950b7f277c56a06/1533467096519/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg ITALIAN FACTS INDEX - Malattia dell' OCCHIO SECCO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659fdbf950b7f277c56a05/5b659fdbf950b7f277c56a0e/1533467156111/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg ITALIAN FACTS INDEX - TRATTAMENTO<br>della malattia dell'occhio secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659fdbf950b7f277c56a05/5b659fdbf950b7f277c56a10/1533467042687/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg ITALIAN FACTS INDEX - Il FILM LACRIMALE 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a2d/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a25/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a17/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a23/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a31/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a3b/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a19/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a29/1530301710913/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a37/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a1b/1532882169360/Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a27/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a39/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a41/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a33/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a2b/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a15/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a1d/1532882169362/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a1f/1532882169364/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_4+mit+%C3%96L-Schicht.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a02/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a35/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fdbf950b7f277c56a13/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f93f950b7f277c563f2/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f93f950b7f277c563f0/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659f93f950b7f277c563f6/5b659f93f950b7f277c563fb/1533394260945/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg ITALIAN FACTS INDEX - ISPEZIONE più PROFONDA<br>... quasi un<br>piccolo glossario https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659f93f950b7f277c563f6/5b659f93f950b7f277c563f9/1533394067580/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg ITALIAN FACTS INDEX - PANORAMICA<br>... per la<br>comprensione più profonda https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b659f93f950b7f277c563f6/5b659f93f950b7f277c563f7/1533394078134/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg ITALIAN FACTS INDEX - SGUARDO VELOCE<br>... abbastanza di tutto per tutti<br>per essere informato https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f93f950b7f277c563ec/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f93f950b7f277c563ee/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f93f950b7f277c563f4/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a04/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a0a/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549f6/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549f4/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549ee/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif ITALIAN FACTS INDEX Un'occhiata al film di lacrime. La fase principale del film lacrimale sovrastante la cornea trasparente è composta dal fluido acquoso della ghiandola lacrimale. Di seguito sono elencate le numerose sporgenze simili a dita delle celle di superficie. La loro cellula legata e le mucine secche e sciolte (filamenti rosa) costituiscono lo strato di mucina basale che lega l'acqua lacrimale alla superficie delle cellule oculari. Le mucine si mescolano con l'acqua e insieme formano un gel di mucin dell'acqua. La superficie del film lacrimale è ricoperta da uno strato di olio molto stretto dai lipidi delle ghiandole di Meibomio. Lo strato lipidico ha lo stesso spessore e la colorazione di un film d'olio su una pozza d'acqua. Una funzione principale dello strato di olio è di ritardare l'evaporazione della fase principale acquosa delle lacrime. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549fa/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a0c/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549cc/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549e8/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ITALIAN FACTS INDEX Il continuo fatturato di lacrime sulla superficie oculare (1) dalla loro produzione principale nella ghiandola lacrimale al di sopra (2) della cornea e della congiuntiva prontamente visibili che devono costantemente fare il bagno in (3) il sistema di drenaggio lacrimale che drena le lacrime nel naso. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549f0/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ITALIAN FACTS INDEX This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a00/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a06/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549f2/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549e1/1533481427023/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg ITALIAN FACTS INDEX - COME OTTENIAMO<br>dell´Occhio Secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549df/1533481192571/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif ITALIAN FACTS INDEX - SINTOMI <br>dell'Occhio Secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549dd/1533481062086/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg ITALIAN FACTS INDEX - il MECCANISMO PATOGENICO<br>dell'occhio secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549db/1533481171012/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg ITALIAN FACTS INDEX - SEGNI CLINICI<br>dell´Occhio Secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549d9/1533480682677/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ITALIAN FACTS INDEX - Il FLUSSO<br>di LACRIME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549d7/1533480731310/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif ITALIAN FACTS INDEX - Il FILM Lacrimale https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549d5/1533480765362/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg ITALIAN FACTS INDEX - I COPERCHI OCCHIALI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549d1/1533481769407/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITALIAN FACTS INDEX - PERCHÉ l'occhio secco<br>tende a PEGGIONARE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549cf/1533481294271/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg ITALIAN FACTS INDEX - SINDROMI del DOLORE<br>dell´Occhio Secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a04d562fa7f5d53549ce/5b65a04d562fa7f5d53549d3/1533480601478/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ITALIAN FACTS INDEX - La SUPERFICIE OCULARE<br>in DETTAGLIO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a08/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549e4/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549ea/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d5354a02/1512819831670/ ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549f8/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549fc/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif ITALIAN FACTS INDEX Un OCCHIO SECCO moderato mostra in genere solo un leggero rossore della Congiuntiva e dei margini del coperchio che può indicare una condizione infiammatoria come descritto dal termine "cheratocongiuntivo itis sicca". Gli orifizi delle ghiandole dell'olio di Meibomio sono spesso ostruiti da secretum visibile o invisibile (che rappresenta la causa primaria più frequente della malattia dell'occhio secco). Il volume lacrimale è basso a causa dell'evaporazione dell'acqua e il tessuto dell'epitelio della superficie oculare ha molti piccoli difetti, che si presentano come piccole macchie nella colorazione vitale con una macchia verde (fluoresceina) osservata in luce blu. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549fe/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549e6/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a04d562fa7f5d53549ec/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01812/1532882092274/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01804/1532882092256/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be0180c/1532882092267/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01802/1532882092253/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01808/1532882092262/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be017fc/1532882092245/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be017f6/1532882092237/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01800/1532882092250/Blink-NUR-QUER-Beschnitten-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel_2_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be0180e/1532882092270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be017f8/1532882092239/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be017fa/1532882092242/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_Gelber-Zettel_500-7-0%2C8_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01806/1532882092259/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___MeibomDr%C3%BCsen+Dysfunction_OHNE+TEXT_20_.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be017fe/1532882092248/Animation_Ectropion%2C-Ektropium_NEU-auf-gelbem-Zettel_400-4-0%2C2_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be0180a/1532882092264/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f0470a6adef3be01810/1532882092272/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed274b/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2759/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2763/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif ITALIAN FACTS INDEX Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2761/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif ITALIAN FACTS INDEX ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2751/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed2744/1533477844626/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg ITALIAN FACTS INDEX - LENTI A CONTATTO e Superficie Oculare https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed2740/1533477733981/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif ITALIAN FACTS INDEX - FATTORI CAUSATIVI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed2742/1533477755245/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png ITALIAN FACTS INDEX - SEGNI CLINICI PRINCIPALI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed2746/1533477806324/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg ITALIAN FACTS INDEX - FATTORI DI RISCHIO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed273e/1533477714512/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png ITALIAN FACTS INDEX - FUNZIONE DI BASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b65a00f1ae6cf3410ed273d/5b65a00f1ae6cf3410ed2748/1533477773056/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg ITALIAN FACTS INDEX - SINTOMI PRINCIPALI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed275b/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2755/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2767/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed275d/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed274f/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed275f/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif ITALIAN FACTS INDEX Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2757/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed273b/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed276b/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif ITALIAN FACTS INDEX L'igiene insufficiente è un fattore cruciale nell'usura delle lenti a contatto e determina un più alto tasso di infezioni oculari nei portatori di lenti a contatto . I microbi possono essere introdotti dalle dita di chi li indossa o dall'uso dell'acqua del rubinetto, che dovrebbe essere omessa. Alcuni tipi di microbi si verificano anche sulla normale superficie oculare. I microbi crescono sulle lenti e nei contenitori di stoccaggio e formano " biofilm " adesivi che li proteggono dalla pulizia e dalla rimozione.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2769/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2765/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif ITALIAN FACTS INDEX The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed2753/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a00f1ae6cf3410ed274d/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659edfaa4a99f2119a3b47/1533386462708/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659e66aa4a99f2119a3146/1532540329562/1_OSCB-Berlin.org_%28c%29ENK_FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659f1c1ae6cf3410ed131c/1532762642572/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659fac0e2e72aae86f9beb/1532763190297/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b659ff62b6a286b620b1888/1532763545826/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ITALIAN FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b65a02c70a6adef3be0311a/1532763907469/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ITALIAN FACTS INDEX https://oscb-berlin.org/fra-facts-index daily 0.75 2018-08-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d38/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d06/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d22/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif Faits sur la maladie de l'œil sec Le renouvellement continu des larmes à la surface oculaire (1) de leur production principale dans la glande lacrymale au-dessus (2) de la cornée et de la conjonctive facilement visibles dans lesquelles ils doivent constamment se baigner dans (3) le système de drainage lacrymal nez. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d36/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif Faits sur la maladie de l'œil sec Un EYE SEC SEC modéré ne montre généralement qu'une légère rougeur des marges de la conjonctive et du couvercle, ce qui peut indiquer un état inflammatoire tel que décrit par le terme «Kératoconjonctiv itis sicca». Les orifices des glandes sébacées de Meibomius sont souvent obstrués par un secret visible ou invisible (qui représente la cause primaire la plus fréquente de la sécheresse oculaire). Le volume des larmes est faible en raison de l'évaporation de l'eau et le tissu de l'épithélium de la surface oculaire présente de nombreux petits défauts qui apparaissent sous forme de petites taches dans la coloration vitale (fluorescéine) observées en lumière bleue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d30/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d44/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d3e/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d20/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d32/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d2c/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d26/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d34/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d28/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif Faits sur la maladie de l'œil sec Un aperçu du TEAR FILM. La phase principale du film lacrymal recouvrant la cornée transparente est composée du fluide aqueux provenant de la glande lacrymale. Ci-dessous les nombreuses saillies en forme de doigt des cellules de surface. Leurs mucines sécrétées (filaments roses), liées et lâches, constituent la couche de mucine basale qui lie l'eau lacrymale à la surface de la cellule oculaire. Les mucines se mélangent à l'eau et forment ensemble un gel eau-mucine. La surface du film lacrymal est recouverte d'une couche d'huile très étroite provenant des lipides des glandes de Meibomius. La couche lipidique a la même épaisseur et la même coloration qu'un film d'huile sur une flaque d'eau. Une des fonctions principales de la couche d'huile est de retarder l'évaporation de la phase aqueuse principale des larmes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d2e/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d42/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d17/1534590356635/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg Faits sur la maladie de l'œil sec - PATHO-MÉCANISME de la Sécheresse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d11/1534589868930/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif Faits sur la maladie de l'œil sec - Le FILM de Larmes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d13/1534589832211/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Faits sur la maladie de l'œil sec - Le LARME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d1b/1534591658428/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg Faits sur la maladie de l'œil sec - COMMENT POUVONS-NOUS<br>OBTENIR La Seccheresse ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d0d/1534590923954/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Faits sur la maladie de l'œil sec - La Surface Oculaire<br>en DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d19/1534590655121/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif Faits sur la maladie de l'œil sec - SYMPTÔMES de la<br>sécheresse oculaire https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d15/1534590894635/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg Faits sur la maladie de l'œil sec - SIGNES CLINIQUES de la<br>sécheresse oculaire https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d09/1534590572797/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg Faits sur la maladie de l'œil sec - Syndromes de la DOULEUR<br>dans la Yeux Secs https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d0b/1534591350147/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Faits sur la maladie de l'œil sec - POURQUOI La Sécheresse Oculaire<br>ELLE TENDANCE à se DÉTÉRIORER ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a21a032be49d46cb3d08/5b72a21a032be49d46cb3d0f/1534590160234/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg Faits sur la maladie de l'œil sec - La PAUPIÉRE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d3c/1512819831670/ Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d3a/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d24/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d1e/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d40/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d2a/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Faits sur la maladie de l'œil sec This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a21a032be49d46cb3d46/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a0a8c2241b9b3840a0a4/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a0a8c2241b9b3840a0a0/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a0a8c2241b9b3840a0a6/5b72a0a8c2241b9b3840a0a9/1534529065797/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg Faits sur la maladie de l'œil sec - LA VUE GLOBALE<br>quelques détails plus cliniques https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a0a8c2241b9b3840a0a6/5b72a0a8c2241b9b3840a0ab/1534529077810/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg Faits sur la maladie de l'œil sec - LA PERSPICACITÉ<br>pour le contexte scientifique https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a0a8c2241b9b3840a0a6/5b72a0a8c2241b9b3840a0a7/1534524161134/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg Faits sur la maladie de l'œil sec - LA VUE RAPIDE<br>quelques points d'intérêt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a0a8c2241b9b3840a0a2/1534528636719/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a0a8c2241b9b3840a09e/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a0a8c2241b9b3840a09c/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg Faits sur la maladie de l'œil sec Le début d'un grand voyage ... avec des amis https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e51fd/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e521b/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e51ff/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e520b/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5201/1532882169360/Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5225/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5217/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e520f/1530301710913/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5203/1532882169362/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e520d/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51f6/1534361368685/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg Faits sur la maladie de l'œil sec - FILM de LARMES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51ee/1534263328013/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg Faits sur la maladie de l'œil sec - SURFACE OCULAIRE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51f4/1534361459213/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg Faits sur la maladie de l'œil sec - TRAITEMENT de la sécheresse oculaire https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51f2/1534525063271/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg Faits sur la maladie de l'œil sec - THÉRAPIE PHYSIQUE des PAUPIÈRES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51f0/1534361437824/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg Faits sur la maladie de l'œil sec - LENTILLES de CONTACT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a17388251bc6c91e51eb/5b72a17388251bc6c91e51ec/1534361414177/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg Faits sur la maladie de l'œil sec - MALADIE des YEUX SECS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5219/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5213/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5221/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e51e9/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5211/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5223/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e51f9/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5205/1532882169364/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_4+mit+%C3%96L-Schicht.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5209/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e521d/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e51fb/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5215/1512819831615/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e5207/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a17388251bc6c91e521f/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46680/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4668e/1534075112210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46694/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif Faits sur la maladie de l'œil sec Schéma de principe d'une lentille de contact souple de taille moyenne sur l'oeil et partiellement derrière les couvercles. Ces lentilles sont appelées lentilles cornéo-sclérales car elles atteignent la sclérotique au- dessus de la cornée . C'est le type de lentilles de contact le plus utilisé. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4666c/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46686/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46682/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46696/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif Faits sur la maladie de l'œil sec Les lentilles de contact « rigides » sont généralement plus petites et reposent exclusivement sur la cornée. Ils ont besoin d'un certain temps d'adaptation pour le porteur et sont donc moins répandus, mais possèdent un matériau inerte et une qualité optique supérieurs. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4669e/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46688/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4667c/1534526923795/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46692/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d46679/1534527221976/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg Faits sur la maladie de l'œil sec - SYMPTOMES Principaux https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d46677/1534527240524/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg Faits sur la maladie de l'œil sec - FACTEURS DE RISQUE importants https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d46675/1534527285138/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg Faits sur la maladie de l'œil sec - LENTILLES DE CONTACT et la Surface Oculaire https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d46673/1534527178364/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png Faits sur la maladie de l'œil sec - SIGNES CLINIQUES Principaux https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d46671/1534527139915/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif Faits sur la maladie de l'œil sec - FACTEURS CAUSANTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b72a1b5562fa741a1d4666e/5b72a1b5562fa741a1d4666f/1534527112300/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png Faits sur la maladie de l'œil sec - FONCTION BASIQUE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4669a/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif Faits sur la maladie de l'œil sec La structure fine de l'épithélium de surface peut subir une détérioration lorsqu'elle est exposée à l'influence d'une lentille de contact. On voit ici le changement de l'épithélium conjonctival bulbaire dans la zone d'excursion d'une lentille de contact souple. Les cellules de surface cubiques avec des cellules caliciformes intercalées pour la production de mucines adhésives dans l'eau sont remplacées par un épithélium squameux sans cellules caliciformes dans un processus appelé « métaplasie squameuse ». https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46684/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4668c/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46698/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Faits sur la maladie de l'œil sec Mouvement d'une lentille de contact souple sur la surface du globe oculaire et derrière les paupières. La lentille de contact se déplace à chaque mouvement du globe oculaire et sur les yeux qui clignotent fréquemment. La quantité de frottement mécanique à la surface oculaire est généralement accrue lors de l'usure des lentilles de contact, même lorsque le film lacrymal est suffisant. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4667e/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d46690/1534075112212/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4668a/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d4669c/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1b5562fa741a1d466a0/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif Faits sur la maladie de l'œil sec Une hygiène insuffisante est un facteur crucial de l'usure des lentilles de contact et entraîne un taux plus élevé d'infections oculaires chez les porteurs de lentilles de contact . Les microbes peuvent être introduits par les doigts de l'utilisateur ou par l'utilisation de l'eau du robinet, ce qui devrait être omis. Certains types de microbes apparaissent également sur la surface oculaire normale. Les microbes se développent sur les lentilles et dans les récipients de stockage et forment des « biofilms » adhésifs qui les protègent contre le nettoyage et le retrait. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94ea/1532882092250/Blink-NUR-QUER-Beschnitten-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel_2_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94e4/1532882092242/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_Gelber-Zettel_500-7-0%2C8_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94f8/1532882092270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94fa/1532882092272/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94f2/1532882092262/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94ec/1532882092253/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94f4/1532882092264/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94e8/1532882092248/Animation_Ectropion%2C-Ektropium_NEU-auf-gelbem-Zettel_400-4-0%2C2_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94e2/1534070394577/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____RISIKO+FAKTOREN%2C+internal+and+external+RISK+FACTORS_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94ee/1532882092256/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94e0/1532882092239/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94e6/1532882092245/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94de/1532882092237/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94f0/1532882092259/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___MeibomDr%C3%BCsen+Dysfunction_OHNE+TEXT_20_.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94fc/1532882092274/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729be62b6a2826587f94f6/1532882092267/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729b7b4d7a9c9cf5e5f630/1533386462708/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b729c3d8a922d2ba98a7c49/1533386524275/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a111898583c37b22d8ec/1533386668558/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a19088251bc6c91e531a/1533386742344/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg Faits sur la maladie de l'œil sec https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b72a1f2f950b752f9462e01/1533386796851/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg Faits sur la maladie de l'œil sec https://oscb-berlin.org/por-facts-index daily 0.75 2018-08-10 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e44985c/1532882092259/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___MeibomDr%C3%BCsen+Dysfunction_OHNE+TEXT_20_.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449854/1532882092248/Animation_Ectropion%2C-Ektropium_NEU-auf-gelbem-Zettel_400-4-0%2C2_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e44984e/1532882092239/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e44984c/1532882092237/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449868/1532882092274/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449850/1532882092242/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_Gelber-Zettel_500-7-0%2C8_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449862/1532882092267/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449856/1532882092250/Blink-NUR-QUER-Beschnitten-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel_2_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449858/1532882092253/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449852/1532882092245/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449866/1532882092272/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449860/1532882092264/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e44985a/1532882092256/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e44985e/1532882092262/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab78d8a922df70e449864/1532882092270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab7fe758d461002641d64/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab7fe758d461002641d5c/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg POR - Facts Index The START of a great JOURNEY ... with friends https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab7fe758d461002641d5e/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab7fe758d461002641d66/5b6ab7fe758d461002641d6d/1532882137120/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg POR - Facts Index - Copy of Deeper INSIGHT<br>Glossary for the scientific background https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab7fe758d461002641d66/5b6ab7fe758d461002641d6a/1532882137118/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg POR - Facts Index - Copy of OVERVIEW<br>Some more clinical detail https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab7fe758d461002641d66/5b6ab7fe758d461002641d67/1532882137114/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg POR - Facts Index - Copy of Quick GLIMPSE<br> Some things of interest https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab7fe758d461002641d62/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab7fe758d461002641d60/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f52f/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f529/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f539/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif POR - Facts Index ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f516/1525165516307/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png POR - Facts Index - Copy of BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f51a/1524398222202/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png POR - Facts Index - Copy of MAIN CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f51c/1532969308153/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg POR - Facts Index - Copy of CONTACT LENSES & Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f51e/1532969296245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg POR - Facts Index - Copy of Important RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f520/1532969295940/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg POR - Facts Index - Copy of MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab8bdaa4a9924dba3f515/5b6ab8bdaa4a9924dba3f518/1524395165433/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif POR - Facts Index - Copy of CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f544/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f52d/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f53f/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif POR - Facts Index The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f527/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f53c/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif POR - Facts Index Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f533/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f525/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f52b/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f542/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f531/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f523/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f535/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f546/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif POR - Facts Index Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f537/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif POR - Facts Index Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab8bdaa4a9924dba3f513/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff78/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff86/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff80/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff5d/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff64/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff70/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff5a/1533232816579/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg POR - Facts Index - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff4a/1533232663774/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POR - Facts Index - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff50/1525631222034/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif POR - Facts Index - Copy of The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff4e/1525631222031/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg POR - Facts Index - Copy of The EYE LIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff4c/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png POR - Facts Index - Copy of The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff52/1525631222040/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif POR - Facts Index - Copy of The Tear FLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff56/1533156107801/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg POR - Facts Index - Copy of PATHO-MECHANISM of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff48/1532637963476/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg POR - Facts Index - Copy of PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff58/1533232816574/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif POR - Facts Index - Copy of SYMPTOMS of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ab919aa4a9924dba3ff47/5b6ab919aa4a9924dba3ff54/1525631222044/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg POR - Facts Index - Copy of CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff68/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif POR - Facts Index A glimpse into the TEAR FILM. The main phase of the Tear Film overlying the transparent cornea is composed of the aqueous fluid from the lacrimal gland. Below are the numerous finger-like protrusions of the surface cells. Their cell bound and and loose secreted mucins (pink filaments) constitute the basal mucin layer that binds the tear water to the ocular cell surface. Mucins mix with the water and together they form a water-mucin gel. The surface of the Tear Film is covered by a very narrow oil layer from the-lipids of the Meibomian glands. The lipid layer has the same thickness and coloring as an oil film on a puddle of water. A main function of the oil layer is to retard the evaporation of the aqueous main phase of the tears. Consequently a lipid deficiency due to a dysfunction of the Meibomian glands is presently reported as the main causative factor for Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff5f/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff66/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff7c/1512819831670/ POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff82/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff6e/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff62/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POR - Facts Index The continuous Turnover of Tears at the Ocular Surface goes (1) from their main production in the lacrimal gland over (2) the readily visible cornea and conjunctiva that they must constantly bathe into (3) the lacrimal drainage system that drains the tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff74/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff6a/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POR - Facts Index This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff7a/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff6c/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff72/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff45/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff76/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif POR - Facts Index A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that may indicate an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low due to water evaporation and the tissue of the Ocular Surface epithelium has many small defects, that occur as small spots in vital staining with a green stain (fluorescein) observed in blue light. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff7e/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab919aa4a9924dba3ff84/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POR - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ab86d758d461002642ce0/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POR - Facts Index 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TERAPIA del Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee442898583552579e30d/5b6ee442898583552579e314/1534688079921/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg Ficha informativa de la Ojo Seco - TERAPIA de PÁRPADOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee442898583552579e30d/5b6ee442898583552579e312/1534687856039/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg Ficha informativa de la Ojo Seco - LENTES DE CONTACTO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee442898583552579e30d/5b6ee442898583552579e30e/1525003517317/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg Ficha informativa de la Ojo Seco - Copy of DRY EYE DISEASE 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e327/1532882169364/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_4+mit+%C3%96L-Schicht.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e33e/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e325/1532882169362/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e337/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e31b/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e341/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e329/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e333/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e31d/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee442898583552579e34b/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee38b1ae6cf931b95a6ef/1534093146623/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg Ficha informativa de la Ojo Seco El COMIENZO de un gran VIAJE ... con amigos https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee38b1ae6cf931b95a6f9/5b6ee38b1ae6cf931b95a6fc/1534089503926/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg Ficha informativa de la Ojo Seco - VISIÓN COMPLETA<br>Algunos detalles clínicos más https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee38b1ae6cf931b95a6f9/5b6ee38b1ae6cf931b95a6fe/1534089619949/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg Ficha informativa de la Ojo Seco - VISIÓN MÁS PROFUNDA<br>Glossary para el conocimiento científico https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee38b1ae6cf931b95a6f9/5b6ee38b1ae6cf931b95a6fa/1534089535584/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg Ficha informativa de la Ojo Seco - MIRADA RAPIDA<br>Algunas cosas de interés https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee38b1ae6cf931b95a6f3/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee38b1ae6cf931b95a6f1/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee38b1ae6cf931b95a6f5/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee38b1ae6cf931b95a6f7/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaf1/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaae3/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaeb/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaff/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaf9/1512819831670/ Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaae7/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Ficha informativa de la Ojo Seco Este diagrama animado esquemático ilustra la función principal del párpado de la propagación de lágrimas: las lágrimas seproducen en la fisura palpebral solo durante el aumento de la secreción de lágrimas. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaadd/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif Ficha informativa de la Ojo Seco El FLUJO de LÁGRIMA en la superficie ocular va (1) de su producción principal en la glándula lagrimal sobre (2) la córnea y la conjuntiva fácilmente visibles en las que deben bañarse constantemente (3) el sistema de drenaje lagrimal que drena las lágrimas en el nariz. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caab01/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaae9/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaafb/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaac1/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaf5/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaef/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caab03/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaed/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaad6/1534873639531/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg Ficha informativa de la Ojo Seco - ¿CÓMO OBTENEMOS Ojo Seco ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaad4/1534708607759/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif Ficha informativa de la Ojo Seco - SÍNTOMAS de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaad2/1534708477323/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg Ficha informativa de la Ojo Seco - El PATHO-MECANISMO de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaad0/1534708691027/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg Ficha informativa de la Ojo Seco - SIGNOS CLÍNICOS de Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaace/1534708039782/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Ficha informativa de la Ojo Seco - El FLUJO de LÁGRIMA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaacc/1534708197204/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif Ficha informativa de la Ojo Seco - La PELICULA LAGRIMAL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaaca/1534708549515/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg Ficha informativa de la Ojo Seco - Los PÁRPADOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaac6/1534873576927/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Ficha informativa de la Ojo Seco - ¿POR QUÉ el Ojo Seco EMPEORA ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaac4/1534708839095/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg Ficha informativa de la Ojo Seco - Chronic PAIN Syndromes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee512352f5356c8caaac3/5b6ee512352f5356c8caaac8/1534707941848/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Ficha informativa de la Ojo Seco - La Superficie Ocular en DETALLE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaad9/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaadf/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaf3/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif Ficha informativa de la Ojo Seco Un ojo seco moderado típicamente muestra sólo un leve enrojecimiento de los márgenes de la conjuntiva y la tapa que pueden indicar un estado inflamatorio tal como se describe por el término'Keratoconjunctiv SIIT sicca'. Los orificios de las glándulas sebáceas de Meibomio a menudo están obstruidos por secreciones secretas visibles o invisibles (que representan la causa principal más frecuente de la enfermedad ocular seca). El volumen de lágrimas es bajo debido a la evaporación del agua y el tejido del epitelio de la superficie ocular tiene muchos defectos pequeños, que aparecen como manchas pequeñas en la tinción vital con una mancha verde (fluoresceína) observada en la luz azul. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaaf7/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaae5/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif Ficha informativa de la Ojo Seco   Un vistazo al PELÍCULA LAGRIMAL. La fase principal de la película lagrimal que recubre la córnea transparente está compuesta por el fluido acuoso de la glándula lagrimal. Debajo están las numerosas protuberancias similares a dedos de las células de la superficie. Sus mucinas secretadas y unidas a células (filamentos rosados) constituyen la capa basal de mucina que une el agua de lágrima a la superficie de la célula ocular. Las mucinas se mezclan con el agua y juntas forman un gel de agua y mucina. La superficie de la película lagrimal está cubierta por una capa de aceite muy estrecha de los lípidos de las glándulas de Meibomio. La capa de lípidos tiene el mismo espesor y coloración que una película de aceite en un charco de agua. Una función principal de la capa de aceite es retardar la evaporación de la fase principal acuosa de las lágrimas. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaafd/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee512352f5356c8caaadb/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb76/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb86/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Ficha informativa de la Ojo Seco Movimiento de una lente de contacto blanda en la superficie del globo ocular y detrás de los párpados. La lente de contacto se mueve con cada movimiento de la mirada del globo ocular y también con los frecuentes parpadeos. La cantidad de fricción mecánica en la superficie ocular típicamente aumenta en el uso de lentes de contacto, incluso cuando la película lagrimal es suficiente. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb84/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif Ficha informativa de la Ojo Seco Las lentes de contacto están ubicadas directamente sobre la superficie ocular; aquí hay un elemento rígido permeable a los gases (RGP). Las lentes de contacto rígidas son típicamente más pequeñas y se apoyan exclusivamente en la córnea. Necesitan un cierto tiempo de adaptación para el usuario y, por lo tanto, están menos extendidos, pero tienen un material inerte superior y una calidad óptica. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb8c/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb7e/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb70/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb8a/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b837cf26d2a73bb5c1fe5fd/1535343880034/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb6e/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb80/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb7a/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb8e/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif Ficha informativa de la Ojo Seco La Higiene Insuficiente es un factor crucial en el uso de la Lentes de Contacto y resulta en una mayor tasa de infecciones oculares en usuarios de lentes de contacto . Los microbios pueden ser introducidos por los dedos del usuario o por el uso de agua del grifo, que debe omitirse. Ciertos tipos de microbios también ocurren en la superficie ocular normal. Los microbios crecen en las lentes y en los contenedores de almacenamiento y forman ' biofilms ' adhesivos que los protegen contra la limpieza y la eliminación.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb74/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb82/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif Ficha informativa de la Ojo Seco Diagrama esquemático de una lente de contacto blanda típica de tamaño medio en el ojo y parcialmente detrás de las tapas. Estas lentes se denominan lentes de contacto corneoesclerales porque llegan a la esclerótica por encima de la córnea . Este es el tipo de lentes de contacto más utilizado. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb72/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb5e/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b837d8b40ec9a19795487e2/1535344039608/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb78/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb88/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif Ficha informativa de la Ojo Seco The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b6ee4b64ae2373e2bf8fb7c/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png Ficha informativa de la Ojo Seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee4b64ae2373e2bf8fb60/5b6ee4b64ae2373e2bf8fb67/1534700990218/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg Ficha informativa de la Ojo Seco - LENTES DE CONTACTO y Superficie Ocular 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Seco - La FUNCIÓN BÁSICA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee4b64ae2373e2bf8fb60/5b6ee4b64ae2373e2bf8fb63/1534700671127/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif Ficha informativa de la Ojo Seco - FACTORES CAUSATIVOS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b6ee4b64ae2373e2bf8fb60/5b6ee4b64ae2373e2bf8fb69/1534700934255/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg Ficha informativa de la Ojo Seco - Importantes FACTORES RIESGO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b7061364d7a9c32558c9a28/1534091677651/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg Ficha informativa de la Ojo Seco 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9b01ae6cf55a09a2465/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9b01ae6cf55a09a245b/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9b01ae6cf55a09a2471/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9b01ae6cf55a09a244f/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51440/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51424/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51448/1534075112212/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51456/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51450/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif TUR - Dry Eye FACTS INDEX Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51442/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5144c/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif TUR - Dry Eye FACTS INDEX Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51454/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5143e/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d51431/1532969295940/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg TUR - Dry Eye FACTS INDEX - Copy of MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d5142f/1532969296245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg TUR - Dry Eye FACTS INDEX - Copy of Important RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d5142d/1532969308153/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg TUR - Dry Eye FACTS INDEX - Copy of CONTACT LENSES & Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d5142b/1524398222202/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png TUR - Dry Eye FACTS INDEX - Copy of MAIN CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d51429/1524395165433/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif TUR - Dry Eye FACTS INDEX - Copy of CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa23562fa7c4f8d51426/5b77fa23562fa7c4f8d51427/1525165516307/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png TUR - Dry Eye FACTS INDEX - Copy of BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51438/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51458/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif TUR - Dry Eye FACTS INDEX Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51444/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51436/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5144a/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5143c/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5144e/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif TUR - Dry Eye FACTS INDEX ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51452/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif TUR - Dry Eye FACTS INDEX The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d5143a/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51434/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa23562fa7c4f8d51446/1534075112210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8062/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8066/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif TUR - Dry Eye FACTS INDEX The continuous Turnover of Tears at the Ocular Surface goes (1) from their main production in the lacrimal gland over (2) the readily visible cornea and conjunctiva that they must constantly bathe into (3) the lacrimal drainage system that drains the tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8086/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8078/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc806a/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc807e/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8076/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8070/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8064/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8068/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc806c/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif TUR - Dry Eye FACTS INDEX A glimpse into the TEAR FILM. The main phase of the Tear Film overlying the transparent cornea is composed of the aqueous fluid from the lacrimal gland. Below are the numerous finger-like protrusions of the surface cells. Their cell bound and and loose secreted mucins (pink filaments) constitute the basal mucin layer that binds the tear water to the ocular cell surface. Mucins mix with the water and together they form a water-mucin gel. The surface of the Tear Film is covered by a very narrow oil layer from the-lipids of the Meibomian glands. The lipid layer has the same thickness and coloring as an oil film on a puddle of water. A main function of the oil layer is to retard the evaporation of the aqueous main phase of the tears. Consequently a lipid deficiency due to a dysfunction of the Meibomian glands is presently reported as the main causative factor for Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc805f/1533232816579/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg TUR - Dry Eye FACTS INDEX - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc805d/1533232816574/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif TUR - Dry Eye FACTS INDEX - Copy of SYMPTOMS of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc805b/1533156107801/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg TUR - Dry Eye FACTS INDEX - Copy of PATHO-MECHANISM of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc8059/1525631222044/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg TUR - Dry Eye FACTS INDEX - Copy of CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc8057/1525631222040/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif TUR - Dry Eye FACTS INDEX - Copy of The Tear FLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc8055/1525631222034/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif TUR - Dry Eye FACTS INDEX - Copy of The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc8053/1525631222031/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg TUR - Dry Eye FACTS INDEX - Copy of The EYE LIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc804f/1533232663774/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif TUR - Dry Eye FACTS INDEX - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc804d/1532637963476/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg TUR - Dry Eye FACTS INDEX - Copy of PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77fa702b6a28a662fc804c/5b77fa702b6a28a662fc8051/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png TUR - Dry Eye FACTS INDEX - Copy of The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8080/1512819831670/ TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8074/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8082/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc807c/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc804a/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc808a/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8072/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8084/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc806e/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif TUR - Dry Eye FACTS INDEX This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc807a/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif TUR - Dry Eye FACTS INDEX A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that may indicate an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low due to water evaporation and the tissue of the Ocular Surface epithelium has many small defects, that occur as small spots in vital staining with a green stain (fluorescein) observed in blue light. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77fa702b6a28a662fc8088/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77f8d8758d46b6ff7cbe3e/5b77f8d8758d46b6ff7cbe43/1534277508832/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg TUR - Dry Eye FACTS INDEX - Copy of Deeper INSIGHT<br>Glossary for the scientific background https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77f8d8758d46b6ff7cbe3e/5b77f8d8758d46b6ff7cbe3f/1534277454136/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg TUR - Dry Eye FACTS INDEX - Copy of Quick GLIMPSE<br> Some things of interest https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b77f8d8758d46b6ff7cbe3e/5b77f8d8758d46b6ff7cbe41/1534277479867/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg TUR - Dry Eye FACTS INDEX - Copy of OVERVIEW<br>Some more clinical detail https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8d8758d46b6ff7cbe3a/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8d8758d46b6ff7cbe38/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8d8758d46b6ff7cbe34/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg TUR - Dry Eye FACTS INDEX The START of a great JOURNEY ... with friends https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8d8758d46b6ff7cbe3c/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8d8758d46b6ff7cbe36/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f82f032be447993e3384/1533386462708/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9e6b8a0455bb1e4fd8c/1533386742344/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f8a3562fa7c4f8d50db0/1533386524275/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg TUR - Dry Eye FACTS INDEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77f9714fa51a76f3553105/1533386668558/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg TUR - 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Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b780164b8a0455bb1e52187/1532205869827/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB_offene+T%C3%9CR+als+START+ohne+Text+16b_.jpg TUR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b7800388a922da6923febfd/1531648124365/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif TUR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b7800cfcd8366741a7b0236/1531671049156/Augenoberfl%C3%A4che+%C3%9CBERGANG+FOTO+EIGENES+AUGE+TROCKENES+AUGE+und+W%C3%9CSE+KAMELE_NEU_50%25_+.jpg TUR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b78013a88251b5c02147543/1531665830735/OSCB-Bild_5.0+FOTO+Lid+Margin+als++BANNER+2_aus+Ophthalmologe+2009_3+jpg9_.jpg TUR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b7800606d2a7356c6f4ef0f/1531649657780/WasserTROPFEN+auf+Blatt+wie+Tr%C3%A4nen%2C+OPT+BREITER+_Fr%C3%BChjhar+2016_.jpg TUR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b77ffdc8a922da6923fe9da/1531667947231/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg TUR - Home Index https://oscb-berlin.org/ita-home-index daily 0.75 2018-10-03 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792fb7aa4a99fdf3a11e25/1534591183717/Augenoberfl%C3%A4che+%C3%9CBERGANG+FOTO+EIGENES+AUGE+TROCKENES+AUGE+und+W%C3%9CSE+KAMELE_NEU_50%25_+.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b795c6e40ec9a9bc88da053/1534680176489/OSCB+HOMEPAGE+ITALIANO+als+BANNER+BILD+breiter+seitlicher+Rand.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792eee03ce646d8c6ad705/1534590940999/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792f4540ec9a9bc88cbd83/1534591072013/WasserTROPFEN+auf+Blatt+wie+Tr%C3%A4nen%2C+OPT+BREITER+_Fr%C3%BChjhar+2016_.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b7930ac032be447994794e9/1534591332570/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB_offene+T%C3%9CR+als+START+ohne+Text+16b_.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792f8c1ae6cf55a0a3866c/1534591150919/39-12fps_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2860cm-72dpi%29+GIF_2.gif ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b793053575d1fcc4918a6aa/1534591290284/OSCB-Bild_5.0+FOTO+Lid+Margin+als++BANNER+2_aus+Ophthalmologe+2009_3+jpg9_.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b79301888251b5c021db5f3/1534591258651/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792fe2562fa7c4f8de8f6a/1534591224312/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ITA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b792f18aa4a99fdf3a11b42/1534591032241/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ITA - Home Index https://oscb-berlin.org/ara-home-index daily 0.75 2018-10-03 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81286bcd8366d1f2c2ad2a/1534591332570/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB_offene+T%C3%9CR+als+START+ohne+Text+16b_.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8127802b6a282494d337ce/1534591072013/WasserTROPFEN+auf+Blatt+wie+Tr%C3%A4nen%2C+OPT+BREITER+_Fr%C3%BChjhar+2016_.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8127dd0ebbe8b9b8cc005d/1534591224312/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8126e94d7a9cb23e4979e4/1534590940999/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b812744562fa70992dd473b/1534591032241/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b812828758d46345dd5f8c2/1534591290284/OSCB-Bild_5.0+FOTO+Lid+Margin+als++BANNER+2_aus+Ophthalmologe+2009_3+jpg9_.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8127b2352f53cbba2a1f5b/1534591183717/Augenoberfl%C3%A4che+%C3%9CBERGANG+FOTO+EIGENES+AUGE+TROCKENES+AUGE+und+W%C3%9CSE+KAMELE_NEU_50%25_+.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8127f92b6a282494d3399e/1534591258651/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b812798575d1f3286c0b6f5/1534591150919/39-12fps_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2860cm-72dpi%29+GIF_2.gif ARA - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b903da1cd83667e00deb933/1536179630615/Arabic+Translators+Team+%28breiter+Rand%29jpg.jpg ARA - Home Index https://oscb-berlin.org/ara-facts-index daily 0.75 2018-09-22 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32812/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32836/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c3280f/1533232816579/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg ARA - Facts Index - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c3280d/1533232816574/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_6v6_Klein_10+LINK+Bildchen_.gif ARA - Facts Index - Copy of SYMPTOMS of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c3280b/1533156107801/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg ARA - Facts Index - Copy of PATHO-MECHANISM of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c32809/1525631222044/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg ARA - Facts Index - Copy of CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c32807/1525631222040/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ARA - Facts Index - Copy of The Tear FLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c32805/1525631222034/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif ARA - Facts Index - Copy of The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c32803/1525631222031/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg ARA - Facts Index - Copy of The EYE LIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c327ff/1533232663774/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ARA - Facts Index - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c327fd/1532637963476/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg ARA - Facts Index - Copy of PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8141a8cd8366d1f2c327fc/5b8141a8cd8366d1f2c32801/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ARA - Facts Index - Copy of The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3281e/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ARA - Facts Index يوضح هذا الرسم التخطيطي المتحرك وظيفة غطاء العين الرئيسية لنشر المسيل للدموع - تحدث قطرات المسيل للدموع الفعلية في الشق الجوفي فقط أثناء زيادة إفراز المسيل للدموع. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32820/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3281a/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3282e/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32828/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32834/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3283b/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32830/1512819831670/ ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32816/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ARA - Facts Index الحركة المستمرة للدموع على سطح العين (1) من إنتاجهم الرئيسي في الغدة الدمعية فوق (2) القرنية والملتحمة الواضحة للعيان التي يجب أن تغمر بالدموع باستمرار إلى (3) نظام التصريف الدمعي الذي يستنزف الدموع في أنف. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32818/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32824/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3281c/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif ARA - Facts Index لمحة عن فيلم المسيل للدموع تتكون المرحلة الرئيسية من فيلم المسيل للدموع الذي يغطي القرنية الشفافة من السائل المائي من الغدة الدمعية. أدناه هي نتوءات عديدة تشبه الإصبع من الخلايا السطحية. وتشكل خلاياهم المَحْكَرَة والمفصولة (الخيوط الوردية) طبقة الميسين القاعدية التي تربط الماء المسيل للدموع بسطح الخلية العينية. يخلط الميوسين مع الماء ويشكلان معًا جزيء ماء موسين. يتم تغطية سطح فيلم الدموع بطبقة دهنية ضيقة جدًا من الدهون في غدد ميبونين. الطبقة الدهنية لها نفس السمك والتلوين كفيلم زيتي على بقع ماء. إن الوظيفة الرئيسية للطبقة الدهنية هي إعاقة تبخير المرحلة الرئيسية المائية للدموع. وبالتالي فإن نقص الدهون بسبب خلل في غدد ميبونين هو حاليا العامل الرئيسي المسبب لأمراض جفاف العين. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c327fa/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32822/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32814/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32826/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3282a/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif ARA - Facts Index عادةً ما تظهر العين المعتدلة الجافة فقط احمرارًا خفيفًا في الملتحمة وهامش الجفن التي قد تشير إلى وجود حالة التهابية كما هو موصوف في المصطلح ´Keratoconjunctivitis sicca´. غالبًا ما يتم عرقلة فتحات الغدد الزيتية بواسطة إفرازات مرئية أو غير مرئية (والتي تمثل السبب الأساسي الأكثر شيوعًا لمرض العين الجاف). حجم الدمعة منخفض بسبب تبخر الماء ونسيج ظهارة سطح العين لديه العديد من العيوب الصغيرة ، التي تحدث كبقع صغيرة في تلطيخ حيوي مع بقعة خضراء (فلوريسين) لوحظ في الضوء الأزرق. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c3282c/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32838/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141a8cd8366d1f2c32832/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cd2/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cc4/1530301710913/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cb6/1532882169360/Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cc2/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cd4/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cb8/1532882169362/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cc0/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cb2/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cce/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cd6/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349c9e/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cb4/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cd8/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349ccc/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349ca1/1536174953956/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg ARA - Facts Index - مرض جفاف العين https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349cab/1536174916448/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg ARA - Facts Index - الغشاء الدمعي https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349ca5/1536174994740/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg ARA - Facts Index - العدسات اللاصقة https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349ca9/1536175060800/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg ARA - Facts Index - العلاج https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349ca7/1536175084526/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg ARA - Facts Index - العلاج https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81407d70a6ad58d0349ca0/5b81407d70a6ad58d0349ca3/1536174806285/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg ARA - Facts Index - سطح العين https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cae/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cca/1512819831615/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cbc/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cbe/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cda/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cc8/1530301710919/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cd0/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cb0/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cba/1532882169364/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_4+mit+%C3%96L-Schicht.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81407d70a6ad58d0349cc6/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee03/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee11/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee0b/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee25/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif ARA - Facts Index Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee09/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee17/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee0f/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee05/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee21/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edfe/1536402834236/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg ARA - Facts Index - الأعراض الرئيسية https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edfc/1536402888583/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg ARA - Facts Index - عوامل الخطر الهامة https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edfa/1536402957745/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg ARA - Facts Index - العدسات اللاصقة والمسطح العيني https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edf8/1536402731360/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png ARA - Facts Index - علامات سريرية رئيسية https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edf4/1536402602603/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png ARA - Facts Index - الوظيفة الأساسية https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8140b721c67c8d1fa6edf3/5b8140b721c67c8d1fa6edf6/1536402698938/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif ARA - Facts Index - العوامل المؤثرة https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6edf1/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee15/1534075112212/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee23/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee19/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif ARA - Facts Index Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee1d/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif ARA - Facts Index Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee13/1534075112210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee01/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee1b/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif ARA - Facts Index ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee07/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee0d/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8140b721c67c8d1fa6ee1f/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif ARA - Facts Index The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bb5/1532882092245/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bc3/1532882092264/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bad/1532882092237/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bbb/1532882092253/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bb7/1532882092248/Animation_Ectropion%2C-Ektropium_NEU-auf-gelbem-Zettel_400-4-0%2C2_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bc9/1532882092272/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bbd/1532882092256/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bb1/1534237670971/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____RISIKO+FAKTOREN%2C+internal+and+external+RISK+FACTORS_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bc7/1532882092270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bb9/1532882092250/Blink-NUR-QUER-Beschnitten-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel_2_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bc1/1532882092262/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bc5/1532882092267/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bb3/1532882092242/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_Gelber-Zettel_500-7-0%2C8_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31baf/1532882092239/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bbf/1532882092259/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___MeibomDr%C3%BCsen+Dysfunction_OHNE+TEXT_20_.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813ffccd8366d1f2c31bcb/1534277202992/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81404221c67c8d1fa6ea3f/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81404221c67c8d1fa6ea3b/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ARA - Facts Index بداية رحلة رائعة ... مع الأصدقاء https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81404221c67c8d1fa6ea43/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81404221c67c8d1fa6ea3d/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81404221c67c8d1fa6ea41/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81404221c67c8d1fa6ea45/5b81404221c67c8d1fa6ea46/1535281201697/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg ARA - Facts Index - لمحة سريعة<br>بعض الأشياء المثيرة للاهتمام https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81404221c67c8d1fa6ea45/5b81404221c67c8d1fa6ea4a/1535281491235/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg ARA - Facts Index - نظرة أعمق<br>مسرد لمعلومات الخلفية https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b81404221c67c8d1fa6ea45/5b81404221c67c8d1fa6ea48/1535281337921/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg ARA - Facts Index - نظرة عامة<br>بعض التفاصيل السريرية https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b813fe0352f53cbba2a8baa/1533386462708/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b814018575d1f3286c1281c/1533386524275/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81405e1ae6cfab3d101ef5/1533386668558/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b81409cc2241ba1810eff54/1533386742344/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ARA - Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8141331ae6cfab3d1023c1/1533386796851/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ARA - Facts Index https://oscb-berlin.org/por-home-index daily 0.75 2018-10-03 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b816d3770a6ad58d035f2c7/5b816d3770a6ad58d035f2ca/1535210127362/FAHNEN-KOMBINATION-f%C3%BCr-ANIMATION-wehend-animiert-transparent-200x291_flaggenbilder_10-0%2C5.gif POR - Home Index - The LANGUAGES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b816d3770a6ad58d035f2c7/5b816d3770a6ad58d035f2c8/1535210113363/DEUTSCH_deutschland-fahne-016-wehend-animiert-transparent-200x291_flaggenbilder.de_WEB10_.gif POR - Home Index - Deutsch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b816e1bb8a045cacc7f1f66/1534668925739/OSCB+HOMEPAGE+Englisch+ALT+als+BANNER+BILD+mit+Rand+4.jpg POR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b816db64ae237f5ab27d490/1534591224312/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg POR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b816d9803ce64a5a9a5d291/1534591183717/Augenoberfl%C3%A4che+%C3%9CBERGANG+FOTO+EIGENES+AUGE+TROCKENES+AUGE+und+W%C3%9CSE+KAMELE_NEU_50%25_+.jpg POR - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b816dfa88251bb51feac242/1534591290284/OSCB-Bild_5.0+FOTO+Lid+Margin+als++BANNER+2_aus+Ophthalmologe+2009_3+jpg9_.jpg POR - 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Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b816d3770a6ad58d035f2c5/1534590940999/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg POR - Home Index https://oscb-berlin.org/jpn-home-index daily 0.75 2018-10-03 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8271d103ce64a5a9ad7bc5/1534591183717/Augenoberfl%C3%A4che+%C3%9CBERGANG+FOTO+EIGENES+AUGE+TROCKENES+AUGE+und+W%C3%9CSE+KAMELE_NEU_50%25_+.jpg JPN - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8272360ebbe8b9b8d57e12/1534591290284/OSCB-Bild_5.0+FOTO+Lid+Margin+als++BANNER+2_aus+Ophthalmologe+2009_3+jpg9_.jpg JPN - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b827163b8a045cacc86c2e7/1534591032241/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif JPN - Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8271b1352f53cbba339f62/1534591150919/39-12fps_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2860cm-72dpi%29+GIF_2.gif JPN - 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Home Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8271f44ae237f5ab2f9522/1534591224312/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg JPN - Home Index https://oscb-berlin.org/jpn-facts-index daily 0.75 2018-08-26 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b82882f8a922d08001df578/5b82882f8a922d08001df57d/1535298977879/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge+%281%29.jpg JPN - Dry Eye Facts Index - Deeper Insight<br>科学的背景の用語集 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b82882f8a922d08001df578/5b82882f8a922d08001df57b/1535298910114/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge.jpg JPN - Dry Eye Facts Index - Overview<br>いくつかの臨床的詳細 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b82882f8a922d08001df578/5b82882f8a922d08001df579/1535298860031/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BPATIENT%2Bmit%2BAuge.jpg JPN - Dry Eye Facts Index - Quick Glimpse<br>興味のあるもの https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b82882f8a922d08001df574/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b82882f8a922d08001df572/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b82882f8a922d08001df570/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b82882f8a922d08001df56e/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg JPN - Dry Eye Facts Index 偉大な旅の始まり...友達と https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b82882f8a922d08001df576/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa58/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa66/1534075112210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa70/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif JPN - Dry Eye Facts Index Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa60/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa74/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa76/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa6c/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif JPN - Dry Eye Facts Index Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa64/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa5e/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa4f/1532969296245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg JPN - Dry Eye Facts Index - Copy of Important RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa4b/1524398222202/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png JPN - Dry Eye Facts Index - Copy of MAIN CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa49/1524395165433/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif JPN - Dry Eye Facts Index - Copy of CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa4d/1532969308153/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg JPN - Dry Eye Facts Index - Copy of CONTACT LENSES & Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa47/1525165516307/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png JPN - Dry Eye Facts Index - Copy of BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289158a922d08001dfa46/5b8289158a922d08001dfa51/1532969295940/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Symptoms+Typische+SYMPTOME+des+Trockenen+AUGES_10+LINK+BILDCHEN_START3_.jpg JPN - Dry Eye Facts Index - Copy of MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa6a/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa5c/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa72/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif JPN - Dry Eye Facts Index The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa62/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa54/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa68/1534075112212/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye+Drops+can+DAMAGE+the+Ocular+Surface_20_.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa5a/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa56/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa78/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif JPN - Dry Eye Facts Index Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa6e/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif JPN - Dry Eye Facts Index ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289158a922d08001dfa44/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8ad4/1532882092245/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8ae9/1532882092272/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8acc/1532882092237/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif JPN - 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Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8adc/1532882092256/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8ad0/1534237670971/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____RISIKO+FAKTOREN%2C+internal+and+external+RISK+FACTORS_20_.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8ae1/1532882092262/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8287a6cd8366d1f2cc8ae7/1532882092270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8288d40ebbe8b9b8d5ea85/5b8288d40ebbe8b9b8d5ea90/1525631117993/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg JPN - Dry Eye Facts Index - Copy of The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8288d40ebbe8b9b8d5ea85/5b8288d40ebbe8b9b8d5ea8e/1526917165245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg JPN - Dry Eye Facts Index - Copy of TREATMENT of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8288d40ebbe8b9b8d5ea85/5b8288d40ebbe8b9b8d5ea8c/1525003619062/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg JPN - Dry Eye Facts Index - Copy of EYELID THERAPY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8288d40ebbe8b9b8d5ea85/5b8288d40ebbe8b9b8d5ea8a/1525003540262/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg JPN - 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Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8288d40ebbe8b9b8d5ea97/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8288d50ebbe8b9b8d5eab9/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8288d50ebbe8b9b8d5eaab/1530301710916/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8288d50ebbe8b9b8d5eab7/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8288d40ebbe8b9b8d5eaa3/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b07/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537ad5/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537aff/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b05/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif JPN - Dry Eye Facts Index A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that may indicate an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low due to water evaporation and the tissue of the Ocular Surface epithelium has many small defects, that occur as small spots in vital staining with a green stain (fluorescein) observed in blue light. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537aef/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b13/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537af1/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif JPN - Dry Eye Facts Index The continuous Turnover of Tears at the Ocular Surface goes (1) from their main production in the lacrimal gland over (2) the readily visible cornea and conjunctiva that they must constantly bathe into (3) the lacrimal drainage system that drains the tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b0d/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b01/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537afb/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537af5/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537af7/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif JPN - Dry Eye Facts Index A glimpse into the TEAR FILM. The main phase of the Tear Film overlying the transparent cornea is composed of the aqueous fluid from the lacrimal gland. Below are the numerous finger-like protrusions of the surface cells. Their cell bound and and loose secreted mucins (pink filaments) constitute the basal mucin layer that binds the tear water to the ocular cell surface. Mucins mix with the water and together they form a water-mucin gel. The surface of the Tear Film is covered by a very narrow oil layer from the-lipids of the Meibomian glands. The lipid layer has the same thickness and coloring as an oil film on a puddle of water. A main function of the oil layer is to retard the evaporation of the aqueous main phase of the tears. Consequently a lipid deficiency due to a dysfunction of the Meibomian glands is presently reported as the main causative factor for Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b03/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537afd/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b11/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif JPN - Dry Eye Facts Index 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289994d7a9cb23e537ad7/5b8289994d7a9cb23e537ad8/1532637963476/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg JPN - Dry Eye Facts Index - Copy of PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b8289994d7a9cb23e537ad7/5b8289994d7a9cb23e537adc/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png JPN - Dry Eye Facts Index - Copy of The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b0b/1512819831670/ JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537af3/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537af9/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif JPN - Dry Eye Facts Index This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b09/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png JPN - Dry Eye Facts Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8289994d7a9cb23e537b0f/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif JPN - Dry Eye Facts Index 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167aa3/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167a9d/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167a97/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167aa5/1512819831611/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167ab3/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167aad/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167a99/1525171512288/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167a9f/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167aab/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32999758d46ce63167ab1/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f81/1524396532220/ARZT-Symbol+%28GR%C3%9CN%29_%C3%9Cberarbeitet+3R+KLEIN.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fb3/1524399664531/SMILEY+Clever%2C+Genie%2C+Brille+ENK_%C3%9Cberarbeitet_Symbolbild+3+KLEIN.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f9d/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f97/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f91/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5aef0d5788251b5dc45586c9/1525616339815/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_START3_.jpg POL-Facts-Index - SOCZEWKI KONTAKTOWE I POWIERZCHNIA OKA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5adc788ef950b79d821d1f8e/1525172163264/OSCB-Bild_6.0_Dry+Eye+Disease_Typical+Symptoms+in+Dry+Eye+Disease+UNstable+or+Blurred+VISION%2C+IRRITATION%2C+PAIN_10.jpg POL-Facts-Index - GŁOWNE DOLEGLIWOŚCI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5adc788ef950b79d821d1f8c/1525172131941/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png POL-Facts-Index - GŁÓWNE OBJAWY KLINICZNE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5adc788ef950b79d821d1f88/1525172188136/OSCB-Bild_6.0_Dry+Eye+Disease_Some+Important+RISK+FACTORS+%2B+WAGE.png POL-Facts-Index - Ważne CZYNNIKI RYZYKA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5adc788ef950b79d821d1f8a/1525172061437/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif POL-Facts-Index - CZYNNIKI PRZYCZYNOWE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc788ef950b79d821d1f83/5adc788ef950b79d821d1f84/1525172043347/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png POL-Facts-Index - PODSTAWOWE FUNKCJE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f95/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f9b/1524322506524/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fad/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fab/1512819831644/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif POL-Facts-Index Ultrastruktura nabłonkapowierzchni oka może ulec zaburzeniu na skutek oddziaływania soczewki kontaktowej. Pokazano tutaj zmiany nabłonka spojówki w strefie wypływu miękkiej soczewki kontaktowej.Sześcienne komorki powierzchowne przetykane komórkami kubkowymi produkującymi hydrofilne mucyny są zastępowane przez płaski nabłonek bez komórek kubkowych w procesie nazywanym ´metaplazja płaskonabłonkowa´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fa5/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif POL-Facts-Index Schematyczny diagram typowij średniej wielkości Miękkiej Soczewki Kontaktorej naOku i częściowo pod Powiekami. Takie soczewki są określane jako rogówkowo-twardówkowe ponieważ sięgają poza rogówkę na twardówkę. Jest to najczęściej stosowany typ soczewek kontaktowych. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fa1/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f93/1525169837607/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fb1/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif POL-Facts-Index Niewystarczająca higiena jest kluczowym czynnikiem ryzyka stosowania Soczewek Kontaktowych i skutkuje wyższym odsetkiem infekcji oczu u osób noszących soczewki kontaktowe. Mikroorganizmy mogą być wprowadzane przez palce użytkownika lub przez używanie wody z kranu, której należy unikać. Pewne typy drobnoustrojów występują również na normalnej powierzchni oka. Mikroorganizmy rosną na soczewkach i w pojemnikach do ich przechowywania i wytwarzają przyczepny biofilm chroniący je przez przed środkami czyszczącymi i przed usunięciem. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fa3/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f9f/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fa9/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif POL-Facts-Index Ruchomość Miękkiej Soczewki Kontaktowej na Powierzchni Gałki Ocznej i pod Powiekami. Soczewka Kontaktowa porusza się z każdym ruchem gałki ocznej podczas patrzenia oraz przy częstym mruganiu. Zakres mechanicznego tarcia jest zwykle nasilony u noszących soczewki kontaktowe nawet, jeśli film łzowy jest wystarczający. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1f99/1524320573439/OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN__DRY+SPOT+FLUO_KLEIN+20cm-72dpi_10fps+GIF.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1fa7/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif POL-Facts-Index ´Twarde´ Soczewki Kontaktowe są typowo mniejsze i w całości spoczywają na rogówce. Wymagają pewnego czasu na adaptację przez użytkownika i dlatego są rzadziej stosowane, ale wykonane są z bardzo dobrego niedrażniącego materiału i mają doskonałą jakość optyczną. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc788ef950b79d821d1faf/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d68058981187e00014b3291/1567098262130/Animation_Trockenes-Auge%2BGef%C3%A4sse%2BR%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b51d/1529854655172/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_NUR+QUER.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b531/1530216741888/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b519/1529751003534/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b52b/1529244871759/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b514/1529244871746/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b525/1529244871755/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___MeibomDr%C3%BCsen+Dysfunction_OHNE+TEXT_20_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b521/1529854665315/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b355c8803ce6435b6b0d28b/1530223761741/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b512/1529244871744/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b527/1529244871757/OSCB-GIF-FUNCTIONAL-UNIT-7-...%2BL%C3%84NG.%C3%9CBERg%C3%A4nge-%2BBLINZELN-NEU-%2BOSCB_3x-LANGS%2C-NUR-Blinnzeln-OHNE-Tr%C3%A4nen_SAUBER_NUR-Auge_KURZ-%2B-INKOMPLETTER-LIDSCHLAG_491-15-0%2C4_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b52f/1529837688336/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b51b/1529244871750/Animation_Ectropion%2C-Ektropium_NEU-auf-gelbem-Zettel_400-4-0%2C2_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b523/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b353ea18a922d62fcf9b52d/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b38bcd3758d4623ef37613d/1530445019969/Animation_Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_600-4-1%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef0c8903ce64705662cf92/1525615761032/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32ce303ce641bc8976d44/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef0c45575d1f65bdfc6810/1525619498309/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32ce303ce641bc8976d46/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae594101ae6cfa83d4584d8/1524995096345/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32ce303ce641bc8976d42/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ad32ce303ce641bc8976d40/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef0c5b1ae6cf459ee55894/1525615778923/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5b4/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POL-Facts-Index Ten schematyczny animowany diagram ilustruje zasadniczą funkcję powieki w rozprowadzaniu łez - faktyczne krople łez pojawiają się w szparze powiekowej tylko podczas zwiększonego wydzielania https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb59a/1524324495489/SMILEY+Clever%2C+Genie%2C+Brille+ENK_%C3%9Cberarbeitet_Symbolbild+KLEIN.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5be/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5b0/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5c4/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5c6/1512819831670/ POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5b8/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5cc/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5aa/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5bc/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5ce/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5b6/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5c8/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5c2/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5ac/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5d0/1524397496620/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5c0/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif POL-Facts-Index A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that indiates an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low and the tissue of the Ocular Surface epithelium has many small defects, that occurs as small spots in vital staining with a blue stain (fluorescein). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5ba/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5b2/1512819831654/The-Tear-FILM-%26-The-OCULAR-SURFACE__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5ae/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POL-Facts-Index Stały Przepływ Łez na Powierzchni Oka (1) z miejsca ich głównej produkcji w gruczole łzowym poprzez (2) dobrze widoczną rogówkę i spojówkę, które muszą być stale nawilżone, po (3) system dróg łzowych odprowadzających łzy do nosa https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb5a5/1525172809644/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif POL-Facts-Index - Jak Zapadamy na Zespół Suchego Oka https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb59f/1525172590419/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg POL-Facts-Index - Zespoły BÓLOWE w Zespole Suchego Oka https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb5a1/1525172555273/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif POL-Facts-Index - Typowe OBJAWY KLINICZNE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb5a3/1525172524086/OSCB-Bild_6.0_Dry+Eye+Disease_Typical+Symptoms+in+Dry+Eye+Disease+UNstable+or+Blurred+VISION%2C+IRRITATION%2C+PAIN_10cm.jpg POL-Facts-Index - TYPOWE DOLEGLIWOŚCI w Zespole Suchego Oka https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb59d/1525172716135/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__LIPID+DEFICIENCY+induces+Tear+Film+Deficiency+and+Surface+Damage.gif POL-Facts-Index - ZESPÓŁ SUCHEGO OKA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc78f4aa4a99f4733fb59c/5adc78f4aa4a99f4733fb5a7/1525172411670/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png POL-Facts-Index - Powierzchnia Oka w SZCZEGÓŁACH https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc78f4aa4a99f4733fb5ca/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d67e44b4646780001e848c7/1567089740715/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease___Augenoberfl%C3%A4che+und+Dr%C3%BCsen_Ocular+Surface+and+Glands_%2B+MGD+%2B+W%C3%BCste+%2B+Kamele+50%25+HELL+50_20_.jpg POL-Facts-Index https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d67fd281fda3c0001623d40/1567096107240/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge_Neu.jpg POL-Facts-Index https://oscb-berlin.org/product-galleries daily 0.75 2018-09-09 https://oscb-berlin.org/produkte daily 0.75 2018-12-13 https://oscb-berlin.org/produkte-2 daily 0.75 2020-01-01 https://oscb-berlin.org/new-folder daily 0.75 2020-01-29 https://oscb-berlin.org/informationparts daily 0.75 2020-07-14 https://oscb-berlin.org/404-page-not-found daily 0.75 2018-07-21 https://oscb-berlin.org/news daily 0.75 2018-07-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a307afa5790a100dcc3f7e/1495710654759/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a308ee579fb3619e519634/1495710663973/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a305ab6a496354332c1141/1495710678322/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926de386b8f5b492fb9c0ea/1495719493105/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ad62264402435c094c24da/1495710811492/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592708d16b8f5bb4c81510a1/1495730409836/Rudolf+VIRCHOW.PNG Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592715863a0411764a7dc48c/1495733665309/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926ecb9a5790a6c9614893b/1495723201320/ Congresses Panel Discussion on Contact Lenses at the 2016 Congress of the Algerian Society of Ophthalmology https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58777094579fb3c2eacd8f01/1484222617076/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5927032e414fb5234ed4db82/1495729036664/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58777cc620099e396ba5c7c4/1495710767127/TFOS+DEWS+II+.+Post+ARVO+2016+Meeting_20160506_161841.jpg Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58777480b8a79b37023cb613/1495710803506/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592017206b8f5be82861fcb9/1495710640981/ARVO+2017+COMMUNICATOR_15-72_frei.jpg Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926eb1acd0f686d4aff5530/1495734727712/ Congresses Dr. Moatez MEKKI (left) together with Donald TAN (middle) from Singapore and colleagues during the Middle East African Council for Ophthalmology (MEACO) congress 2017 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926bfeb579fb3c38afa848c/1495711735971/20170509_193757LIME+Diner+with+talk+of+Donald+KORB+at+ARVO+2017_Reiko+ARITA+%2B+Donald+KORB_6.jpg Congresses Reiko ARITA (left) presents a gift to the invited speaker Donald KORB (right) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59201bf0b3db2b2e45f5d9ae/1495710722430/NADJA+Knop+and++ERICH+Knop+k.png Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926c019440243acfaf790f1/1495711779654/IMG_5923_2x+LIME+Diner+with+talk+of+Donald+KORB+at+ARVO+2017_von+Reiko+ARITA_12-180dpi_.jpg Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587782326b8f5bdeb6f20991/1495710756990/ Congresses Poster Presentation of the NEW DRY EYE CONCEPT at the TFOS Congress 2016 - Great audience and great response - (Photo courtesy of Heiko Pult) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592715c4725e2558bbf52349/1495733710056/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926e205d2b857e254f3cc12/1495720476347/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ad5ddac534a5fbdeca5703/1495710791827/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926c20dbebafbfacb490571/1495712280837/20170509_183459_LIME+Diner+with+talk+of+Donald+KORB+at+ARVO+2017_.jpg Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926f337e4fcb562c78c4919/1495726884596/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926fd0f1b631b55675b816c/1495727385953/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59270303440243e216582cb5/1495728916858/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5926c3dc5016e1695b2e761c/1495712739059/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ad5c7d3e00be979c30a518/1495710699720/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58776e4037c581c2c07d21c1/1495710744935/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587782a4197aea0e71385bda/1484227242466/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59270d4b37c581516a72a514/1495731538312/ Congresses Signature of an official Cooperation Agreement between the Charité and Juntendo in 2011 by the Dean of the Charité Prof. Annette Grüters-Kieslich and by the President of Juntendo University Prof. Eiki Kominami during the World Health Summit 2011 in Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/591f2db22994ca38e7bd307e/1495710632516/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/592708b515d5db8b26268e92/1495730371527/ Congresses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b43340b03ce641f98189f28/1531130895496/oscb-congresses.jpeg Congresses https://oscb-berlin.org/the-ocular-surface daily 0.75 2019-06-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2a7dc7131a5d7e924f3f0/1505929190248/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TEAR-FLOW-at-the-OCULAR-SURFACE-%28UPstream---DOWNstream%29.gif GLIMPSE on ... the Ocular Surface The FUNCTIONAL UNIT of the Ocular Surface. The organs of the Mucosal ADNEXA, the lacrimal gland and the lacrimal drainage system. are not readily seen whereas the Cornea and Conjunctiva that constitute the Ocular Surface ´Proper´ can easily be seen and investigated in clinics. The Organs of the Mucosal Adnexa both ´manage´ the tears in the sense that they either produce the new tears or drain the ´used´tears - whereas the Cornea and Conjunctiva are bathed in between by the tears. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f32cbe58c621b485018e5/1491763850867/ GLIMPSE on ... the Ocular Surface This is a (very) quick overview of the main OCULAR SURFACE components and functions that form an intricate network - repeated viewing helps and proves your interest in the topic (every move you do will of course be tracked) ... in slower versions it may become too boring ;-) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2962b29f187e568ee8f6c/1505924683513/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_DIFFERENT-SYSTEMS-REGULATE-the-Ocular-Surface_.gif GLIMPSE on ... the Ocular Surface The intact function of the Ocular Surface depends on REGULATORY SYSTEMS that support the growth and maturation of the organs and are also necessary for the actual functional regulation, e.g. of the volume of secretion or the frequency of blinking and many other functions that make the ocular surface feel well ... and also the individual who owns it. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e76a647131a556626fd81f/1508338293243/OSCB-Bild_Ocular+Surface_ONJUNCTIVA_The+Human+CONJUNCTIVA%2C+Foto+%C3%9Cbersicht+nasal%2C+eher+hell_.png GLIMPSE on ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a6f422f9a61e863f31bcea/1504113708343/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif GLIMPSE on ... the Ocular Surface The Ocular Surface is the first part of the vision pathway and therefore of utmost importance for everything that happens later and more posterior in the eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587bd96fd1758e3cef02d760/1491763868708/ GLIMPSE on ... the Ocular Surface The Complete Ocular Surface ANATOMICAL UNIT. It consists of the OCULAR MUCOSA, i.e. the organs that are bathed by the tear fluid and of the MUCOSAL ADNEXA, i.e. the organs that manage the tear fluid, either by producing it, as the lacrimal gland, or by draining it after bathing, as the lacrimal drainage system. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586d297637c581815f098a8a/1491763859920/ GLIMPSE on ... the Ocular Surface Early Concept about the FUNCTIONAL UNIT of the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a6f5bb9f8dcef7791c29a6/1504114128306/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif GLIMPSE on ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5898632b9f7456131b07bd50/1491763915881/ GLIMPSE on ... the Ocular Surface The BLINK movement of the Eye Lids spreads the Tears into a very thin and homogenous Layer of Tear Fluid - the Tear FILM - that keeps the mucosal Ocular Surface constantly moist even in the opened palpebral fissure during the interblink period. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590770029de4bb97e1fbf677/5907778ba5790ae9a2424b62/1493661682469/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung.jpg GLIMPSE on ... the Ocular Surface - GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590770029de4bb97e1fbf677/5907773159cc68a9a763137e/1504083411609/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung+%2B+AUGE+QUER+%2B+TR%C3%84NEN.png GLIMPSE on ... the Ocular Surface - OVERVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590770029de4bb97e1fbf677/59bb9249a803bb58bc7faa61/1505465027764/Cornea-DEEPER-INSIGHT_LINK-Bildchen.gif GLIMPSE on ... the Ocular Surface - DEEPER INSIGHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e769e1edaed8bfb4b07fca/1508338162207/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__The-CORNEA-is-the-%C2%B4CLEAR-WINDOW-%C2%B4-of-the-Eye-for-the-Entrance-of-Light-and-thus-for-Vision.gif GLIMPSE on ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a6f4a5f9a61e863f31c637/1518890834554/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye-Disease_Einzel-BILDER_500pix-30-2_.gif GLIMPSE on ... the Ocular Surface Dry Eye Disease is a prototypical disease of the Ocular Surface due to the dysfunctions that eventually impair the most basic functional complex of preserving moisture. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586cd53d59cc684b2ace8bbf/1491763902568/OSCB-GIF_Ocular+Surface+Functional+UNIT+%2C%2C%2C+TEAR+FLOW+ALONG+OS+%28aus+GIF+Functional+Unit%29_2-2fps+GIF_.gif GLIMPSE on ... the Ocular Surface The Tear Flow is along the Organs that constitute the Ocular Surface Functional Unit, i.e. from the Lacrimal Gland, through its excretory ducts on the Cornea and Conjunctiva and further through the Lacrimal Drainage System into the Nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a074cb893fc0b6d3d66df1/1486910677761/ GLIMPSE on ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587604ebc534a5e7e2b4a6a8/1484129516823/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_f%C3%BCr+BANNER%2C+STREIFEN+AUGENOBERFL%C3%84CHE+ATW+%2BUSM_.jpg GLIMPSE on ... the Ocular Surface https://oscb-berlin.org/from-tears-to-the-tear-film daily 0.75 2018-07-15 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58638d58e58c62bfbb459b9c/1504458911796/ Tears & Tear Film BLINKING transforms the TEARS into the Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac3d8dcf81e025e87a499b/1504460198584/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587292b3a5790a9fba8fe2e0/1504459001864/OSCB-Bild_1.2._The+MYSTERIOUS+TRANSFORMATION+of+TEARS+into+the+Tear+FILM+.png Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58638f3eff7c501ec5316764/1504458821323/ Tears & Tear Film Tear FILM INHOMOGENEITY PREVENTS Perfect Visual ACUITY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58639e0d5016e1308c5d1840/1504458835677/ Tears & Tear Film BLINK and Tear Film BREAK-UP Animation with as seen in Fluorescein Vital Staining (schematic) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58639c8d29687f3055c5adef/1504458806449/ Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58638ae537c581f15dbabcde/1482918633784/OSCB-Bild_4.1_Tears+%26+Tear+Film_Ocular+GLANDS+produce+the+TEAR+COMPONENTS.png Tears & Tear Film Ocular GLANDS produce the TEAR COMPONENTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587617d017bffc46dbdfdb0d/1484134359299/TR%C3%84NENTropfen%2C+Wasser+%28PPT%29+%2B+D%C3%BCnner+Heller+Rand+%2B+SPIEGELUNG+%2B+SCHATTEN+%2B+OSCB+verzerrt.png Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac37bbd2b857b87570493f/1504458702114/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D_2.gif Tears & Tear Film The AIR-To-TEAR INTERFACE of the Tear FILM is the MAIN Surface for REFRACTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a2f6d56b8f5bf7981c0a23/1504458899597/ Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a2dcf6579fb3619e506b9d/1487068414814/ Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac372a8dd0417353f4c7a8/1504458548991/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_The-MYSTERIOUS-TRANSFORMATION-of-TEARS-into-the-Tear-FILM_WEB_.gif Tears & Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58639cfe9de4bb1b81dd07c4/1504458846870/ Tears & Tear Film BLINK and Tear Film BREAK-UP Animation with Tear Film Lipid Layer seen in Interferometry (schematic) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58728327e58c622f1606f69e/1483899715849/OSCB-GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2820cm-72dpi%29_33-10fps+GIF.gif Tears & Tear Film https://oscb-berlin.org/contact-lens/introduction daily 0.75 2020-11-07 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59be552dd55b4162d0f1174a/1505645878452/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_COSMETICS%C2%A0and-ESTHETICS-in-Contact-Lens-Wear_Venus.gif OVERVIEW of Contact Lenses We do not know the opinion of Roman Goddess VENUS (the Greek Aphrodite - the goddess of love and beauty) about cosmetic contact lenses but she may likely have preferred to avoid changing her immaculate beauty by wearing glasses. On the other hand, as she is just seawater-foam-born when she arrives here in crete she may have kept in mind that contact lenses are not ideal to wear in water. The most likely conclusion is therefore, that Venus was in fact emmetropic, i.e. she did not have any refractive errors - which is good for her and for us, because we can come to a successful end with our contemplations. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5863db592e69cfccd3b87f44/1504461707106/OSCB-GIF_9.3_ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2880-72%2C12-2%29+GIF.gif OVERVIEW of Contact Lenses Movement of a soft corneoscleral contact lens – the most frequently used lens type - on the ocular surface during eye movements and blinking. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3bf968a3f3504f6d7dbc58/1597766009885/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__600-4-0%2C3.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bee54e80bd5ed4398ed8eb/1505682779464/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac43f337c581aaa46db0d9/1504461821556/OSCB-Berlin.org_Interaction-of-a-CONTACT-LENS-with-the-POSTERIOR-LID-MARGIN_.gif OVERVIEW of Contact Lenses Contact Lens interactions with the Ocular Surface – A crtitical issue is the interaction between contact lens margin, posterior lid border and the corneal rim (limbus). Also, the contact lens margin typically exerts friction onto the bulbar conjunctiva. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b0f7b7a803bb8658c42941/1504769981617/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3bfa0c6b8548418bda12eb/1597766172111/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+must+CLEANED+and+DISINFECTED_Kontaktlinsen+m%C3%BCssen+GEREINIGT+und+DESINFIZIERT+werden+2+NEUTRALISIERUNG_30_.jpg OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5870edca15d5db0c21ec3253/1504461612185/ OVERVIEW of Contact Lenses Here a cartoon of a certainly very subjective view on the potential cosmetic advantage of spectales (this cartoon is often seen on internet pages ... but it was so far impossible for us to identify the original author) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59be6af1cf81e068113476b4/1505651455504/OSCB-Bild_9_Cotact-Lens_Contact-Lenses-FUTURE-Ideas-%28lifeboat.com-blog-2016-03-fish-and-insects-guide-design-for-future-contact-lenses%29_WEB.gif OVERVIEW of Contact Lenses Many tempting ideas for the FUTURE of Contact Lenses (FROM: lifeboat.com blog 2016 03 fish-and-insects-guide-design-for-future-contact-lenses - Posted by Klaus Baldauf) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b0f14fc534a5e094e43776/1504768350797/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aff314cf81e08b0440bc46/1504703274579/OSC039%7E1.GIF OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b10b4d4c0dbfde5dc05c79/1504774999604/OSCB-Berlin.org_INFECTIOUS-COMPLICATIONS-of-CONTACT-LENS-WEAR.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bff071715d174c9345b9e/1597767926821/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif OVERVIEW of Contact Lenses - ORTHO-K Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bfed66b2ced334f576e0b/1597767926326/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES-as-MEDICAL-TOOLS_LINK-Bildchen.gif OVERVIEW of Contact Lenses - CL as MEDICAL TOOLS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bfea795eb430ba8d5837f/1597767926331/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS_LINK-Bildchen.gif OVERVIEW of Contact Lenses - Contact lens HYGIENE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bfe5566961d77eec155a4/1597767926298/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif OVERVIEW of Contact Lenses - Making CONTACTS with the OS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bfde495eb430ba8d55546/1597767926462/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_COSMETICS%C2%A0and-ESTHETICS-in-Contact-Lens-Wear_Venus_LINK-Bildchen.gif OVERVIEW of Contact Lenses - Cosmetics &amp; Esthetics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3bfd7f1808ba4b0a0a188f/5f3bfdab9749b964e86f9956/1597767864810/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN_LINK-Bildchen.gif OVERVIEW of Contact Lenses - OPTICAL ADVANTAGES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aff6d7a9db09ad7b9f9b32/1504704246043/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b12882f43b55e92c2afda5/1504782482054/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_COSMETIC-Contact-Lens-with-printed-Iris-Color_2.png OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59be614da8b2b03df232f33d/1505648983620/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59affdb937c5817a20cf27e1/1504705990728/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b10a223e00bed6f7a6a853/1504774702448/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_The-Normal-Eye-Lid-Margin.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4578cd0f68fff53a75d9/1504462227322/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_SCLERAL-CONTACT-LENSES_WEB_.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b1208af43b55e92c2ab390/1504780435979/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_The-OCULAR-SURFACE-%E2%80%A6-the-EYE-BALL%2C-Bulbus-and-the-INTERIOR-of-the-EYE.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a5db72e69cfb1677b1a9f/1504461593436/ OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5870d7c0579fb3e8f1a86bb0/1504461689588/ OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b0008d03596e51ce1badb7/1504706713800/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ba6b6e37c581d3733d312a/1505389430321/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b103882278e70e9fa85053/1504773018069/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_VITAL-STAINING-of-the-Posterior-Lid-Margin--Lid-Wiper-Epitheliopathy-%28LWE%29_PHOTOS-by-DONALD-KORB%2C-Boston_.gif OVERVIEW of Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a2ef1ebbd1adda9b9e5a3/1483353852042/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif OVERVIEW of Contact Lenses https://oscb-berlin.org/giving daily 0.75 2018-07-11 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bf6f0ad55b41d2e7486340/1505718034826/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif Giving https://oscb-berlin.org/new-page-2 daily 0.75 2019-06-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58667d3fc534a540cf4dfac1/1483111784132/ GLIMPSE on ... Tears and Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac1e05e6f2e1f15718834b/1504452891015/OSCB-Berlin.org_GLANDS-of-dthe-Human-OCULAR-SURFACE_WEB.gif GLIMPSE on ... Tears and Tear Film The DIFFERENT OCULAR GLANDS are shown here in a schematic depiction of the conjunctival sac and an upper eye lid. The eye lid is slightly everted from the eye ball in order to better see the single mucus-producing goblet cells (indicated here as pink dots) that are distributed throughout the conjunctiva. The color code further indicates the aqueous glands in light blue color and the oil producing Meibomian glands in yellow. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58666200ff7c507a0b9d2d7f/1483104800760/ GLIMPSE on ... Tears and Tear Film Individual TEAR DROPS (here from increased tear flow in emotional tearing) provide moisture ... but an eye BLINK is necessary to transform the tears into a homogeneous thin FILM with a layered structure in order to provide regular refraction for perfect vision https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58664563d2b857101f002145/1483111829071/ GLIMPSE on ... Tears and Tear Film TEARS provide the MOISTURE of the Mucosal Ocular Surface, that is a pre-requisite for its TISSUE INTEGRITY and thus for CORNEAL TRANSPARENCY. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5932d18a6b8f5b251c816e83/1496502694990/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS+of+the+Ocular+Surface+%28aus+Concept-GIF%29+.png GLIMPSE on ... Tears and Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac343846c3c4554f421029/1504457810785/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D_2.gif GLIMPSE on ... Tears and Tear Film Corneal Transparency is a pre-requisite for vision but not quite sufficient for perfect visual acuity. Only a thin homogeneous pre-corneal FILM of Tears provides perfect VISION. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac1f39cd39c3b55f96c7c7/1504452462782/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE+%2818cm-72%29_25-5fps_NUR+QUER.gif GLIMPSE on ... Tears and Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5898665a15d5db588f007a10/1493459977868/ GLIMPSE on ... Tears and Tear Film The Flow of TEARS at the Ocular Surface is shown by an animated diagram. The bulk amount of tears is produced by the lacrimal gland and delivered by several excretory ducts into the conjunctival sac. The tear fluid is bathing the ocular surface proper (conjunctiva and cornea) and is then disposed by the lacrimal drainage system into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac1fd69f8dce3db05e2ed7/1504452588139/GIF+FUNCTIONAL+UNIT+%2B+TEARS+REGULATION_aus+GIF+Funct.+Unit+u.+f%C3%BCr_OSCB+HOMEPAGE+ENK___8_Bild4%2B5+ENGLISCH_28cm-72_2-1fps_.gif GLIMPSE on ... Tears and Tear Film https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac2063e3df28884d39679d/1504452723105/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif GLIMPSE on ... Tears and Tear Film Environmental RISK FACTORS - mainly external desiccating environment, contact lenses and certain visual tasks - have a negative influence on the delivered tear fluid on the ocular surface and may lead to ocular dryness. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a076bb893fc0b6d3d67dd1/1486911164921/WasserTROPFEN+auf+Blatt+wie+Tr%C3%A4nen%2C+OPT+BREITER+_Fr%C3%BChjhar+2016_.jpg GLIMPSE on ... Tears and Tear Film https://oscb-berlin.org/blink-in-contact-lenses daily 0.75 2020-12-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aefe6a914e6b7a4a7025d5/1504640633376/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif GLIMPSE on Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5870ce391b631b6a228ac9cb/1483787851553/ GLIMPSE on Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aef7d9d482e950a6550609/1504638947697/ GLIMPSE on Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccd73b3a5949900016ec474/1556968382975/LIDER-%28FRONTAL%29-ANIMATION-BLINZELN_-%2B-KONTAKTLINSE-WEICHE-Corneoscleral-FESTER_%C3%9Cberarbeitet_500-18-0%2C15.gif GLIMPSE on Contact Lenses Conventional soft contact lenses and their movement on the eye ball during a blink are shown in this schematic animation. The contact lens fitting is probably a bit ´loose´ here but eventually depends on the subjective wearing comfort of the individual and on the visual acuity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59be6b67914e6bbca145536f/1505651564727/OSCB-Bild_9_Cotact-Lens_Contact-Lenses-FUTURE-Ideas-%28lifeboat.com-blog-2016-03-fish-and-insects-guide-design-for-future-contact-lenses%29_WEB.gif GLIMPSE on Contact Lenses Many tempting ideas for the FUTURE of Contact Lenses (FROM: lifeboat.com blog 2016 03 fish-and-insects-guide-design-for-future-contact-lenses - Posted by Klaus Baldauf) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a400f5016e16d594720d3/1483358236129/ GLIMPSE on Contact Lenses Contact Lenses (here a soft corneo-scleral lens) are sitting in the middle of the Ocular Surface Unit and interact with all components - from the tear film to the tissue - with pros and cons https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59aef7c0e6f2e1af36692f8a/1504638922962/OSC039%7E1.GIF GLIMPSE on Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a4da8725e25a972acd83c/1483361711826/ GLIMPSE on Contact Lenses Contact lenses can correct refractive power directly in the location where most of the natural refraction occurs - on the Cornea https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccd720715fcc0c6f3b7512d/1556967950119/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_HARD+vs.+SOFT+Contact+Lenses%2C+WEICHE+Flexible+Hydrogel++VS.++HARTE+Kontaktlinsen+auf+FINGER_%C3%9CBEReinander_10_.jpg GLIMPSE on Contact Lenses Soft/ flexible contact lenses (top) are the most popular type and they are somewhat larger than the rigid/ gas permeable contact lenses (bottom) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a472bd1758e371533128d/1483360052525/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif GLIMPSE on Contact Lenses https://oscb-berlin.org/deeper-insight-into-contact-lenses daily 0.75 2020-08-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a6ef1725e25a972adef38/1504462304120/ DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a6f2c8419c2e34239effa/1504463009590/ DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bb90158dd04141662bbb0b/1505464349725/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Progression-%28Neovascularization%29-of-the-Limbal-Marginal-Vessels-of-the-Cornea.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bd124aa9db092e09596503/1505563218943/27+TAGES-KONTAKTLINSEN+im+KONJUNKTIVALSACK_2017+BMJ+Publishing+Group%2C+www.bmj.com+content+358+bmj.j2783%29+SPIEGEL+ONLINE+image-1166778-860_galleryfree-tswz-1166778_OPTj.jpg DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bd483e2aeba555ff06b90e/1505577034265/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REPLACEMENT-SCHEDULES-in-Contact-Lens-Wear.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c03f11715d174c9354ae6/1597769014580/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_WHICH-is-the-IDEAL-%28soft%29-CONTACT-LENS_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - Which is the IDEAL CL ??? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c03d44a22ef7e790b09b9/1597769035993/OSCB-Berlin.org_PARAMETERS-for-Fitting-of-a-CONTACT-LENS-%28Radius-of-Curvature-%2B-Diameter-of-Size%29_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - CL FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c039d0e7db11d7fe3d93e/1597768913210/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REPLACEMENT-SCHEDULES-in-Contact-Lens-Wear_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - REPLACEMENTS &amp; DISPOSABLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c036c2a931c1d20aed63f/1597768853577/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_WEARING-SCHEDULES-in-Contact-Lens-Wear_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - WEARING SCHEDULES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c032a1ad7dc3ab5978c2f/1597768806803/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TYPES-OF-CONTACT-LENSES-ON-THE-OCULAR-SURFACE_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - Basic TYPES of CL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f3c0278d1e076330db597d9/5f3c0279a30fc41313aed7fa/1597768368789/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_A-SHORT-HISTORY-OF-CONTACT-LENS-TYPES_LINK-Bildchen.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING - CL HISTORY &amp; TYPES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bb7ec6b1ffb6fd1523615d/1505459920946/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_A-SHORT-HISTORY-OF-CONTACT-LENS-TYPES-AND-MATERIALS.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING A short overview of Contact Lens TYPES and their HISTORY. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bc08298a02c75c5c157836/1505495093729/OSCB-Berlin.org_PARAMETERS-for-Fitting-of-a-CONTACT-LENS-%28Radius-of-Curvature-%2B-Diameter-of-Size%29.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586a6f6646c3c4a162fe658f/1504463060150/ DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b140cfbebafb8e3e31c0ce/1504788701652/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b1130880bd5e10b2ad12ae/1504776978730/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_SCLERAL-CONTACT-LENSES_WEB_.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bd4e627131a50df25c9ae4/1505578600696/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_WEARING-SCHEDULES-in-Contact-Lens-Wear.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bc1c584c326ddd160d59ef/1505500257104/OSCB-Berlin.org_PARAMETERS-for-Fitting-of-a-CONTACT-LENS-%28Radius-of-Curvature-%2B-too-FLAT-%2B-too-STEEP--%29.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4883f14aa1fbc5919832/1597770770829/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TYPES-OF-CONTACT-LENSES-ON-THE-OCULAR-SURFACE_.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING Different TYPES of Contact Lenses on the Ocular Surface - Contact lenses are used in different types that have a different diameter and thus cover different parts of the ocular surface. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b1404c8dd0417b88ec3bb5/1504788564890/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59beb0f9a803bbc23686caa6/1505669377833/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Alterations-in-Contact-Lens-Wear-SEAL-%28Superior-Epithelial-Arcuate-Lesion%29-of-the-CORNEAL-EPITHELIUM.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bc049ea8b2b06e8e18dec5/1505494184745/Kontaktlinsen-MATERIAL_ALCON-Schematic-representation-of-DailiesTotal1-water-gradient-contact-lenses-%28aus-ContactLensSpectrum-6-2013%29.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3bf489b1f49569791c6a2d/1597764761110/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen+TAGEStragelinsen%2C+Wegwerf+Kontaktlinsen%2C+Disposable+Contact+Lenses_20_.jpg DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bec4bc18b27dca62385c58/1505674442737/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_WHICH-is-the-BEST-Contact-Lens-...-resembles-the-JUDGEMENT-of-PARIS-2.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING The question about the BEST Contact Lens would put a potential judge similarly in trouble as it once happened to the poor shepherd PARIS, who was the son of the legendary king of the legendary city of Troy. He was asked to chose for the most beautiful one among the three Greek goddesses HERA, ATHENA and APHRODITE ... of whom one was more beautiful and tempting then the other ... not to tell about the potential anger of those who would have to be rejected ........ The fact that he had to inspect them nude is probably evidence, that he may have been an early morphologist. We don´t tell here what Paris did but stick to contact lenses, which is probably safer. In order to make the situation even more delicate, each of the goddesses promised Paris a tempting reward in order to convince him to vote for her. In case of contact lenses, Hydrogelia would probably promise ´eternal wettablia´, Siliconia would likely promise ´total oxyphilia´ whereas Rigidia would probably promise ´eternal inert stabilia´ ........ hmmmmm, how about that ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bd48a612abd932dd8e2585/1505577136899/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bbd73b3e00beeb628b2c13/1505482565101/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_WHAT-is-the-IDEAL-%28soft%29-CONTACT-LENS_WEB-30_.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5875fd9ae6f2e175063a2c44/1484127650379/OSCB-GIF_KL+RGP_OSCB%2BText_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_UP+Doppelt+%2B+KONTAKTLINSE+RGP+klein+MOBILER+%2880cm-72dpi%29%2C18-10fps.gif DEEPER INSIGHT into ... Contact Lenses - HISTORY - TYPES - SCHEDULES - FITTING https://oscb-berlin.org/deeper-insight-into-scleral-contact-lenses daily 0.75 2021-03-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4cce2994caa10195f30d/1504464091059/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS.gif Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586b8357d1758eb4882e5129/1504463480507/ Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4ba42994caa10195e415/1504463789574/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-CONSTRUCTION-OF-A-CONTACT-LENS_.gif Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4a5bd55b41cd8b11d8b4/1504463462222/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Market-share-and-Rejuvenated-Interest-in-Scleral-Contact-Lenses.gif Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5891b0b7d1758ec68ef54b05/1504464319080/ Scleral Contact Lenses A SCLERAL CONTACT LENS in contrast can shield the whole cornea including the limbal epithelial stem cell zone against external influences. Even during blinking it remains relatively stable and provides a constant bath of the cornea within the tear fluid - as explained above. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586abb5e579fb3ccd8a24f6d/1483389801696/ Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586abea3e6f2e1c533ec5d66/1483390652565/ Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586b9f2ed482e9282499d0b1/1504464304173/ Scleral Contact Lenses Conventional contact lenses - here a small ´rigid´ gas permeable (RGP) lens - swim in the tear film and need copious tears ... which is a clear disadvantage in Dry Eye Disease and make ´conventional´ contact lenses unsuitable in this condition. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ac4d96d7bdcefdcdc70231/1504464283523/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_SCLERAL-CONTACT-LENSES-provide-a-PROTECTIVE-Microenvironment_.gif Scleral Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/586aac339de4bb268237f998/1483385929106/OSCB-GIF_KL+Scleral_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN+%2B+KONTAKTLINSE+GROSSE+SCLERALLINSE+%2880cm-72dp%29+18-8fps+GIF.gif Scleral Contact Lenses https://oscb-berlin.org/contact-lens-discomfort-cld daily 0.75 2020-11-25 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b9462cedaed8ae88ee7c0f/1505314353245/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_VITAL-STAINING-of-the-Posterior-Lid-Margin--Lid-Wiper-Epitheliopathy-%28LWE%29_PHOTOS-by-DONALD-KORB%2C-Boston_.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ba73db8a02c7a9179d7efc/1505391588059/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-causes-Conjunctival-Epithelial-Cell-Alterations-in-the-Excursion-Zone-of-the-Contact-Lens.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ba6dec8fd4d264522acad1/1505390079318/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ba76d5d2b8570174078649/1505392352860/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bf835849fc2ba7e277cc7e/1505723265190/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Alterations-in-Contact-Lens-Wear-SEAL-%28Superior-Epithelial-Arcuate-Lesion%29-of-the-CORNEAL-EPITHELIUM-%2B-Epithel-SPLIT.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b9475b90badeba4bcf1ffd/1505314659333/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_OSCB-Bild_5.4.1_The-Lid-Marginn_LID-WIPER-Topography%2C-aus-CORNEA-2012_.gif Contact Lens Discomfort (CLD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ba79f137c581d3733d8524/1505393142935/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif Contact Lens Discomfort (CLD) https://oscb-berlin.org/d-oscb daily 0.75 2020-10-23 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee2274440243bbc8a83954/1509126019933/ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee1fecc534a5e94d8f0ffe/1509126019928/OSCB-Bild_3.1.8_Ocular+Surface_REGULATORY+SYSTEMS+3+auf+FOTO+vom+mir_VERSCHIEDENE+SYSTEME+REGULIEREN+die+Augenoberfl%C3%A4che_ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee8496bebafbc81fa35f7c/1509126019919/ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee0888b3db2b4f27f01781/1603475670413/ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f488268e7b0f7a602ecdcd/1509202786548/ResearchGate+LOGO.png Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aac017e1ae6cf0e9e3c39c7/1521222026736/BMSEK_Bilder_Graefe-%C3%9C_OPT_2014-06-18-11_AUSSCHNITT-Hell-2_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594ff95703596e991b1a295c/1509126019899/OSCB-Berlin.org_Tr%C3%A4nenFILM+-+TR%C3%84NEN+%26+AUGENOBERFL%C3%84CHE+%28Tr%C3%A4nenfilm+3D%2C+Augenoberfl%C3%A4che+Zeichnung+%2B+Foto%2C+MONTAGE++%2B+AUGE+QUER+Davos+%2B+%C3%9CBERBLENDET+3%29_.png Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f7f27ef2d09a21ef7b3/1603474944580/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Der START https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f738e7b0f7a602f44d2/1509202786533/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Die STADT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f6e53450a1e3ba84127/1509202786530/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Das KONZEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f690d9297f9ed4f9897/1603475010438/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Die LINKS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f64e4966b0784badf20/1509202786523/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Das INSTITUT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f48f5f8e7b0f7a602f42f4/59f48f6124a694055a5081a1/1509202786518/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin - Die THEMEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee1a7a1b10e3297e3a16ab/1509200962447/IMPROVE+YOUR+TEACHING_Folie6_.JPG Das OSCB - 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Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7fa637c58108eeb663be/1509126019969/Humboldthafen+2014-06-01+18.59+OPT+900p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f9cff7c50a1fe9c1f0a/1509126019963/Hotel+Adlon+%2B+UNTER+DEN+LINDEN_2014-07-02+20.07.22_OPT_Streifen+900p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f98e4fcb5612535acff/1509126019964/Deutsches+Theater+2014-06-18+10.55+OPT+900p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f8fd2b857ace54dbdc5/1509126019959/Brandenburger+Tor_2014-07-02+20.07_OPT_Streifen+900p+2.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f844c0dbf207b3b9678/1509126019957/Bodemuseum%2C+Museumsinsel_DSC01259_OPT%2C+900p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f7f59cc68ca47e585da/1509126019961/Berliner+Dom+u.+Alexanderplatz_DSC01286+OPT_900p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f77579fb3102eff9cde/1509126019956/Berlin%2C+Parlamentarergeb%C3%A4ude_OPT_+2014-07-31+13.00_900p_.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f73e45a7c3aedebb69d/1509126019954/Berlin%2C+KANZLERAMT%2C+Spiegelung+im+Abgeordnetenhaus_OPT_2014-07-31+12.40_900p_.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f65cf81e061786aefeb/1509126019950/Berlin%2C+HAUPTBAHNHOF_OPT_2014-07-31+14.01_900p_.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f5be4fcb5612535a97e/1509126019948/Berlin%2C+HAUPTBAHNHIOF+von+der+Spree+aus_OPT_2014-07-31+12.32_900p_.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/599d7f5a6a496355394e224f/1509126019952/Altes+Museum_DSC01284_OPT%2C+900p%2Cjpg.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f355016e127f1f1004b/1509126019947/BMSEK_Bilder_Virchowplatz+mit+Schirmen+%2B+Charitestr_2014-06-18+10_STREIFEN.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f34d2b8576a0a8eb4d0/1509126019945/BMSEK_Bilder_Strasse+%2B+Eisladen_OPT_2014-06-18+10.49+600p+2.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f2959cc687985a4ad96/1509126019943/BMSEK_Bilder_HU+Graduate+School+2_OPT_2014-06-18+14_STREIFEN+900p+hoch+mit+Fahrr%C3%A4dern.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f1d8419c2d4fd5ab78a/1509126019941/BMSEK_Bilder_HU+Graduate+School+2_OPT_2014-06-18+14_STREIFEN+600p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f0f414fb5fa317e245b/1509126019939/BMSEK_Bilder_Charite+Fakult%C3%A4t+Garten_OPT_2014-06-18+10+%2B+GATE_600p.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2f0520099eb7fbc6adf6/1509126019937/BMSEK_Bilder_Anatomie+Park_OPT_2014-06-18+14.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/58ee2e9be4fcb58489f33b8b/58ee2ed96a4963699e633ef0/1509126019935/BERLIN%2C+Brandenburger+Tor_DSC01295_OPT+stark+gestaucht.jpg Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee21ca893fc0309afc07f0/1509126019931/GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+2_30-2fps_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f499e4ec212d295bb04747/1603476101958/OSCB-BILD_Augenoberfl%C3%A4che_EIN-NEUER-BLICK-auf-die-AUGENOBERFL%C3%84CHE_30-auf-WEB_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin Augen-oberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594ff9206a49632bef9e4170/1509126019901/OSCB-Berlin.org_TROCKENES+AUGE+und+Meibomdr%C3%BCsen+Dysfunction+%28MDD%29.png Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f4880a652dea2687837228/1509202786550/ResearchGate+LOGO.png Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee0a74725e254c7c9ded1b/1603475668322/OSCB-GIF_MEIBOMDR%C3%9CSE%2C+Normal+%2B+Obstruktion+%28Ophthalmologe+2009%29_LIEGT+quer%2C+CROP+oben+f%C3%BCr+Banner_20-72_2-1fps_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin Meibomdrüse & MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee09ed440243bbc8a1970a/1603475672785/ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee124b893fc0309af7b07f/1603476044576/ Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f493e910952624f548817b/1509202786552/OSCB_MAINTNANCE-SYSTEMS---bzw.-LINKS_SYMBOL-Bildchen_.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee1b16725e254c7ca24185/1509126019926/OSCB-BILD_Augenoberfl%C3%A4che_EIN+NEUER+BLICK+auf+die+AUGENOBERFL%C3%84CHE++...BASIC+FUNCTIONAL+COMPLEX+%28%C3%9Cberblick+Funktionelle+Komplexe%29.png Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee0665be6594791f0c6c49/1509126019897/GIF+FUNCTIONAL+UNIT+7+...+OHNE+Text+%2B+L%C3%84NGERE+%C3%9CBERg%C3%A4nge+%2B+BLINZELN+NEU+%2B+OSCB+VERSCHOBEN_TR%C3%84NEN+3x+LANGSAMER_99-5fps_UNT+WEG+f%C3%BCr+BANNER.gif Das OSCB - Forschungszentrum für die Augenoberfläche Berlin https://oscb-berlin.org/deeper-insight-into-the-ocular-surface-1 daily 0.75 2020-11-22 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a708da579fb360d7485165/1508340317708/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif DEEPER INSIGHT into ... The ANATOMICAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5872bbf5197aea5ae697a65d/1508340284308/ DEEPER INSIGHT into ... The ANATOMICAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a707d0d482e9879768a574/1508340109870/OSCB-Berlin.org_The-ORGANS-of-the-OCULAR-SURFACE--are-anatomically-continuous-and-work-together_2.gif DEEPER INSIGHT into ... The ANATOMICAL UNIT The organs of the Ocular Surface are ANATOMICALLY CONTINUOUS as can be seen in Histology. The lacrimal gland is connected via its several excretory ducts (top left: histological micrograph) and the lacrimal drainage system extends continuously from the lacrimal puncta (scanning electron microscopic image, right middle) and further along the lacrimal canaliculi (histological micrograph of longitudinal section, bottom right). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f5817be6594efd88d635b/1508340307213/ DEEPER INSIGHT into ... The ANATOMICAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5872af1ee6f2e1d4216878d5/1508340081554/ DEEPER INSIGHT into ... The ANATOMICAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d547ebbd1a19441b9e8a/1504083709684/OSCB-Bild_3.1.0_Ocular+Surface_ANATOMICAL+UNIT+auf+Dry+Eye+CONCEPT+Layout.png DEEPER INSIGHT into ... The ANATOMICAL UNIT - ANATOMICAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d5cf03596e95f9689db7/1504083727721/OSCB-GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+3_18cm-72dpi_25-4fps_.gif DEEPER INSIGHT into ... The ANATOMICAL UNIT - FUNCTIONAL UNIT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d4cff7e0ab2f59b85b1d/1504970470097/Augenoberfl%C3%A4che+mit+CORNEA+...+SEHR+SCH%C3%96NES+FOTO_Ret.png DEEPER INSIGHT into ... The ANATOMICAL UNIT - CORNEA & EyeBall https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d690c534a57f25f8a4e3/1504083763504/OSCB-Bild_Ocular+Surface_ONJUNCTIVA_The+Human+CONJUNCTIVA%2C+Foto+%C3%9Cbersicht+nasal%2C+eher+hell_.png DEEPER INSIGHT into ... The ANATOMICAL UNIT - CONJUNCTIVA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d81dbf629aaad4bfdd0c/1504083775340/OSCB-Bild_3.2.4.3-3B_Ocular+Surface_GLYCOCYLYX+on+Conjunctival+MICROPROJECTIONS+%28COLORED+TEM%29.png DEEPER INSIGHT into ... The ANATOMICAL UNIT - FINE STRUCTURE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5908d4ce86e6c00e33d85362/5908d88d197aea5f113dd9a1/1504083786003/OSCB-Bild_2_Meibomian+Gland_MEIBOMIAN+GLANDs+%26+Glands+of+the+Ocular+Surface.png DEEPER INSIGHT into ... The ANATOMICAL UNIT - GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874ba9315d5db6e97f5f43b/1484044960655/OSCB-GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+3_18cm-72dpi_25-4fps_UNT+WEG+2_.gif DEEPER INSIGHT into ... The ANATOMICAL UNIT https://oscb-berlin.org/glimpse-on-the-lid-margin daily 0.75 2020-12-21 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fde0eb26a6ad7222f0ba033/1608399904236/OSCB-Berlin.org+%28c%29+ENK_Two+aspects+of+lid+margin+function+-+DYNAMIC+WIPER_.jpg GLIMPSE on the LID MARGIN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fde041a51a86c1b6c16b979/1608399904229/OSCB-Berlin.org+%28c%29+ENK_Two+aspects+of+lid+margin+function+-+STATIC+DAM+vs.+DYNAMIC+WIPER.jpg GLIMPSE on the LID MARGIN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf656742c0045a330db711/1608487617752/OSCB-Berlin.org_The-LID-MARGIN.gif GLIMPSE on the LID MARGIN The meibomian oil glands open far back on the free lid margin (flm in the image), while the glands themselves are hidden inside the eyelid. The gland openings (open arrow in the image) form a regular line of small dots. Behind the gland openings lies the skin-mucosa transition zone (muco-cutaneous junction, mjc in the image), followed by the somewhat thickened epithelial cushion of the lid wiper (lw in the image) which rests on the eyeball. In this slit lamp photo, the lid margin is slightly everted from the eyeball and therefore the lid wiper becomes visible. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59352e78197aeac1169f90f9/1608383346150/ GLIMPSE on the LID MARGIN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf6445ef8e407a9ea40e8e/1608487059357/OSCB-Berlin.org---%28c%29-ENK_LIDRAND+IMG_0287+RET+%2B+Gelber+Zettel_30.jpg GLIMPSE on the LID MARGIN The lid margin lines the palpebral fissure and joins the outside dry-oily skin with the inside aqueous-moist mucosa of the eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf64a9a3b92b153c367832/1608487076910/OSCB-Berlin.org_%28c%29ENK_Der+LIDRAND+-+The+LID+MARGIN_ohne+Text__.jpg GLIMPSE on the LID MARGIN The free lid margin (arrows) lines the palpebral fissure and joins the outside dry-oily skin with the inside aqueous-moist mucosa of the eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fde064a8afbbc271751e4b2/1608399904233/OSCB-Berlin.org+%28c%29+ENK_Two+aspects+of+lid+margin+function+-+STATIC+DAM_.jpg GLIMPSE on the LID MARGIN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587146f1b3db2b7cc83bc035/1483818740795/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28hier+hell+%2B+kontrastreich%29_NUR+UNTERES+DRITTEL+f%C3%BCr+BANNER.jpg GLIMPSE on the LID MARGIN https://oscb-berlin.org/the-ocular-surface-1 daily 0.75 2019-06-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7061a914e6b93d48a45e7/1508340020017/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif OVERVIEW of ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a6fff8f7e0ab8b4a8688d1/1508339783024/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2_.gif OVERVIEW of ... the Ocular Surface The 2 Main FUNCTIONAL COMPLEXES that the Ocular Surface must establish in order to allow the first steps of the Vision process are Tear SECRETION and Tear FILM FORMATION. The Secretion can be divided into 3 Sub-Complexes according to the individual secretion of the 3 main components of the TEAR FILM. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a70566a9db09c270b7e332/1508339688105/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif OVERVIEW of ... the Ocular Surface Negative External Influence Factors are termed RISK FACTORS because they increase the likeliness of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a700d949fc2b184565e072/1508339959979/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif OVERVIEW of ... the Ocular Surface The Organs of the Ocular Surface: The organs of the ocular surface proper (Cornea and conjunctiva) can be readily seen in clinical inspection, even though the lids must be everted to the the palpebral conjunctiva at the posterior side of the eye lids. The organs of the mucosal ocular adnexa can not readily by seen except when technical measures are applied. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588f589abebafb21326c3ee2/1508340026722/ OVERVIEW of ... the Ocular Surface Some typical SYMPTOMS in DRY EYE DISEASE concern those that can easily be verified and quantified, such as alteration of visual acuity, ... and those that involve very subjective feelings such as dryness, irritation and pain. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587beeb46b8f5bc21a2c80f3/1508339771532/ OVERVIEW of ... the Ocular Surface The two MAIN FUNCTIONAL COMPLEXES of the Ocular Surface are illustrated here schematically: (1) SECRETION by the Ocular Glands to provide Moisture and (2) FORMATION of a Tear FILM from the Moisture of the Tear Fluid by the BLINK mechanism of the Eye Lids (Actually, Tear Secretion with running tear drops, as seen here, resembles more the tear overflow in emotional tearing than the normal tear production - it is still used here in order to illustrate some basic things) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58727fb0893fc04c1b70383d/1508339712620/ OVERVIEW of ... the Ocular Surface The moist mucosal ocular surface is endangered by numerous microbes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5890ef6fa5790a37631e7367/1508340043003/ OVERVIEW of ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58727fb0893fc04c1b703840/1508339722136/ OVERVIEW of ... the Ocular Surface Eye Movements and Blinking produce FRICTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a6ffae37c5810de9fc9a7b/1508339942377/GIF+FUNCTIONAL+UNIT+%2B+TEARS+REGULATION_aus+GIF+Funct.+Unit+u.+f%C3%BCr_OSCB+HOMEPAGE+ENK___8_Bild4%2B5+ENGLISCH_28cm-72_2-1fps_.gif OVERVIEW of ... the Ocular Surface The CORNEA and the CONJUNCTIVA with its mucosal adnexa form the ocular surface together with the Tears. Upstream of the conjunctiva are the associated GLANDS that secrete the new TEARS. Tears are a multi-purpose solution with many ingredients that is used for bathing the cornea. Downstream is the LACRIMAL DRAINAGE SYSTEM that drains and discharges the used tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58727fb0893fc04c1b70383c/1508339741699/OSCB-Bild_3.1.3_Ocular+Surface_The+Ocular+Surface+is+a+natural+WETLAND.png OVERVIEW of ... the Ocular Surface The Lacrimal Gland is not quite like the Niagara Falls ... but upon emotional tearing while crying or during stimulated secretionbecause of other reasons the lacrimal gland can produce surprising amounts of aqueous fluid. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58727fb0893fc04c1b70383f/1508339732314/OSCB-Bild_3.1.6_Only+a+MOIST+Cornea+can+stay+TRANSPARENT.png OVERVIEW of ... the Ocular Surface Only a MOIST Cornea can stay TRANSPARENT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7034f2994cafaf0640acd/1508339750136/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif OVERVIEW of ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587bd41bbf629abac09517d4/1508340012743/ OVERVIEW of ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c50200a8b2b0f5e4f62e34/1508339935138/OSCB-GIF_MEIBOM-SECRETION-%2B-DELIVERY_aus-Folien-zur-ANIMATION-etc.-aus-WAKAYAMA-%2B-ISER-2016_HEINRICH-MEIBOM-%28BESSER%29_NEU_19-1.5fps_NEU-Gespeichert-in-PSE_.gif OVERVIEW of ... the Ocular Surface The schematic animation shows a cross-section through a lower eyelid. with the bulbar surface of the cornea to the left. In the posterior part of the lid body are the Meibomian Glands that produce lipids (yellow) for the tear film lipid layer (TFLL) and in the anterior part is the lid muscle (M. orbicularis) that helps to deliver the oily secretum from the ductal system of the gland to the outside onto the posterior lid margin. So ... every one of us has multitude of little oil springs ... and we make great profit from the oil because it is indispensable for ocular surface health and for perfect visual acuity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58727fb0893fc04c1b703841/1508339702144/ OVERVIEW of ... the Ocular Surface Different Systems regulate the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5890eda6579fb3e4efc28a58/1508340034981/ OVERVIEW of ... the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58760415db29d6ab1b3bb6a9/1484129304804/OSCB-GIF+FUNCTIONAL+UNIT+7+...+OHNE+Text+%2B+L%C3%84NGERE+%C3%9CBERg%C3%A4nge+%2B+BLINZELN+NEU%2BOSCB+VERSCH._NUR+TEAR+FLOW_2-2fps_Unt+WEG+2.gif OVERVIEW of ... the Ocular Surface https://oscb-berlin.org/deeper-insight-into-the-cornea daily 0.75 2020-12-11 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e779dfb07869e5602dc7d2/1508342295380/OSCB-Berlin.org_The-LIMBUS-%28Margin%29-of-the-CORNEA-%E2%80%A6-provides-Metabolic-Supply-of-the-Cornea-via-the-Peripheral-Vascular-Net.gif The CORNEA The blood vessels of the maintenance organ of the conjunctiva stop at the margin (limbus) of the cornea. This renders the cornea almost totally transparent .... but makes it dependent on the diffusion of blood components from the peripheral vessels towards the center. It is therefore probably no surprise, that in situations where the central cornea has a lack of supply e.g. of oxygen e.g. by an unsuitable contact lens, the peripheral blood vessels start to grow towards the center of the cornea. This will keep the corneal tissue happy again in terms of metabolism ... but negatively influences the higher order function of transparency. and thus impairs vision. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7e2d1b8a79b3789f1c081/1504174813766/OSCB-Berlin.org_%28c%29ENK_Classification-of-the-Bulbar-Surface-in--CONJUNCTIVA-and-CORNEA.gif The CORNEA ... you are HERE ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5873668303596ecf878ed97e/1508342914845/ The CORNEA The corneal limbal stem cell niche is important for continuous regeneration of the corneal epithelium Deficiency of the stem cells for any reason can lead to overgrowth of the conjunctival epithelium over the cornea (conjunctivalization) with a resulting loss of transparency and visual acuity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b265d246c3c498ebf65cb0/1504863712061/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_STRUCTURE-of-the-CORNEA-%26-SCLERA_WEB-30_.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c0fc04e5dd5bf0eddb753b/1505819658983/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_The-LIMBUS-of-the-CORNEA_HYPOXIA-of-the-Cornea-induces-Growth-of-Vessels-%28%C2%B4Neovascularization%C2%B4%29-onto-the-Cornea.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b402052278e7557ebae453/1505121605096/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-Quadratisch_LINK-Bildchen.gif The CORNEA CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b3e6c39f8dce4dd2355ea4/1504962253796/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_The%C2%A0CORNEA%C2%A0and-the%C2%A0SCLERA%C2%A0together-build-the-WALL-of-the-spherical%C2%A0EYEBALL_WEB-30_.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b64fbe2994caee6bf1ef46/1505120196950/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Production-of-CONNECTIVE-TISSUE--COLLAGEN-FIBERS-by-FIBROBLASTS--CYTES-2_-%2B-Fiber-BUNDLE.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7e20a37c5812192fab5b0/1504174608043/OSCB-Berlin.org_%28c%29ENK_Classification-of-the-Bulbar-Surface-in--CONJUNCTIVA-and-CORNEA.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b40327c534a5103819327d/1505121566484/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Die-WAND-des-AUGAPFELS-besteht-aus-der-KORNEA--und-der-SKLERA_BULBUS-LINK-Bildchen.gif The CORNEA EYEBALL and SCLERA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8e80349fc2b494492257a/1508342861125/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA+%28Spot0965%29---Epithelium%2C-Basement-Membrane%2C-BOWMAN%C2%B4s-Layer_HISTOLOGY-%2B-SCHEMA-ZEICHNUNG__NUR+BOWMAN.jpg The CORNEA BOWMAN´s Layer is the initial zone of the corneal stroma, directly underneath the very thin basement membrane , that is almost invisible in light microscopy. It is about 10 micrometers thick, consists of densely interwoven collagen fibrils and is free of cells. It ends where the first row of keratocytes occur and thus die highly ordered stacks of collagen lamellae start. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7e2814c0dbf3e35545c28/1508341601254/GIF_Animation-BULBUS-Schichten%3B-HORNHAUT-%2B-SKLERA-%2B-BINDEHAUT-%28PSE-8-3%29_ENGLISH_.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8eab9914e6b9940764a2a/1505290943581/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Spot0965_ANATOMY-and-HISTOLOGY-of-the-Human-CORNEA---EPITHELIUM-and-BOWMANs-Membrane_USM_x2-%2BSSCHARF%2C-A.gif The CORNEA The corneal epithelial cells have an extensive cytoskeleton of intermediate filaments (IF) along the cell periphery and around the nucleus. This occurs as a dense fuzzy pattern in the present resolution. The fibers consist of different types of cytokeratin. They join the basal cells with be underlying basement membrane (BM) as IF-Anchoring Filaments and link the cells with each other via desmosomes. Intermediate filaments act like ´ropes´ in the cell for the equal distribution of tensile stress throughout the epithelium. This results in an overall higher mechanical resistance of the epithelium. Cytokeratin is a normal component of all epithelial cells and does not indicate cornification. A squamous cell (small arrow) is seen in the surface layer and an adjacent cell (interrupted arrow) is about to exfoliate into the tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587366ee6a49630b7b3389dd/1483958022561/ The CORNEA The CORNEA does not contain blood and lymph vessels and it therefore depends on the supply with nutrients and blood gases from the peripheral marginal arcades - loops of small blood vessels - in addition to supply via the liquids of the tear film outside and the liquid of the anterior chamber at the inside through the epithelia. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a70b6dcf81e045cfb3de92/1508342130571/ The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b4036bf7e0abec5d1e1d3c/1505121653445/LIMBUS---Hornhautrand_LINK-Bildchen_WEB_.PNG The CORNEA Corneal LIMBUS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8e6423e00beef2526baaf/1508342809966/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Spot0965_ANATOMY-and-HISTOLOGY-of-the-Human-CORNEA---Composite-mit-%C3%9Cbersicht_WEB-30.gif The CORNEA Overview of the Human CORNEA with its Layers and Tissues https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8ea0c51a584a1cb837893/1508342876262/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA-%28Spot0965%29---STROMA-DESCEMETS-MEMBRANE-ENDOthelium%2C_.gif The CORNEA DESCEMET´s Membrane is the basement membrane on which the cells of the corneal endothelium rest. It is quite thick for a basement membrane (please compare with that of the epithelium). The membrane is a dense accumulation of extracellular matrix molecules and it represents one of the strongest components of the cornea ... that may withstand when all other layers are already lost. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8ef82bce176c4a1fbc386/1505292183281/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA-%28Spot0965%29---STROMA-%2B-ENDOthelium-with-WATER-PUMPS.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8e7974c0dbf5255910623/1505290147953/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA-%28Spot0965%29---Epithelium%2C-Basement-Membrane%2C-BOWMAN%C2%B4s-Layer_OVERVIEW-Histo-%2B-Zeichnung-AOF_WEB-30_.gif The CORNEA The histological structure of the cornea is seen in a clinical photo, a schematical drawing and in two histological photomicrographs of increasing magnification. The cornea basically consists of a transparent connective tissue disc of certain curvature that is sealed by different epithelia at the anterior/outer and at the posterior/inner sides. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b3ea00bce17645d643d98e/1508341628967/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_The-WALL-of-the-EYEBALL-consists-of-the-CORNEA--and-the-SCLERA.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a70b4cf5e2319b70246935/1508342120426/ The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8ebec80bd5ee35b4f81d7/1505291252595/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA-%28Spot0965%29---STROMA-DESCEMETS-MEMBRANE-ENDOthelium%2C_.gif The CORNEA The structure of the stroma is somewhat altered here as usually occurs in specimens that are treated by conventional formalin fixation. The lamellae, constituted of tightly packed collagen fibrils, have lost their strictly parallel arrangement and empty spaces occur between them due to swelling of the tissue before fixation. Occasional corneal ´maintenance cells´(fibrocytes/ keratocytes) occur along the collagen lamellae. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8eaa3a8b2b0e31fd1dd8d/1505290920941/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA+%28Spot0965%29---Epithelium%2C-Basement-Membrane%2C-BOWMAN%C2%B4s-Layer_HISTOLOGY-%2B-SCHEMA-ZEICHNUNG_WEB-30_.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8e7ea90badeba4bcc130d/1508342849777/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA---Epithelium%2C-Basement-Membrane%2C-BOWMAN%C2%B4s-Layer-HISTOLOGY-%2B-SCHEMA-ZEICHNUNG--2-AUSSCHNITT.gif The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f156f6223bc7e6b2c84eacc/1595240301067/OSCB-Berlin.org%2C+%28c%29+ENK_CORNEA+-+Ordered+composition+of+Collagen+Fibrils+in+Layers+with+KERATOCYTE+cells_NEU+20_.jpg The CORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5891ced25016e1aafbba02e0/1485951251845/ The CORNEA A SCLERAL CONTACT LENS on the eye covers the complete Cornea including the limbal region in the periphery. ´Sclerals´ shield the cornea against external influences even during the blink. They continuously bathe the cornea in the patient's own tears. Due to new modern high-tech materials and curvature designs this is a ´rejuvenated´ medical tool for calming down chronic corneal dysfunctions and diseases in order to provide an environment for healing. For details please see the Section on Scleral Contact Lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587bf62a579fb3024898f928/1484518972276/Augenoberfl%C3%A4che+mit+CORNEA+von+SOA+HOMEPAGE_Repariert+%28Pfeil+raus%29+%2B+HG+recht+HELLER+%2BKORNEA+BLAU+%2BRd+Reparaturpinsel+%2Bre+Rand+GR%C3%9CN+%2B+LICHTSTRAHLEN.png The CORNEA https://oscb-berlin.org/deeper-insight-into-the-conjunctiva daily 0.75 2020-11-07 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7e8dae3df28057d088461/1561629777029/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE+%2818cm-72%29_25-5fps_NUR+QUER.gif The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5873a726be65949ec2c51a54/1508343334329/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a828ece3df28057d0b9f01/1508343121986/OSCB-Berlin.org_%28c%29ENK_CONJUNCTIVA-Structure-%28Epithelium-%26-Connective-Tissue-Lam.propria%29.gif The Conjunctiva The schematic structure of the bulbar CONJUNCTIVA near the corneal margin (limbus). At the bottom of the Tear Film is the epithelium of the conjunctiva that seals its underlying connective tissue layer (Lamina propria). The loose connective tissue in the Lamina propria is composed of loosely arranged collagen fibers and contains many cells as well as blood vessels (red) and nerve fibers. It is sitting on the densely arrange collagen of the underlying Sclera - the solid wall of the Eye Ball. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5873a832b8a79bc1e78a3ef0/1491411546821/OSCB-Bild_Ocular+Surface_Conjunctiva_The+epithelium+of+human+CONJUNCTIVA+and+CORNEA+produces+LUBRICIN.png The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59e77db0e45a7c0b58164743/1508343226909/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Conjunctival-GOBLET-CELLs-with-excreted--Mucin.gif The Conjunctiva The marginal CONJUNCTIVA in the LID WIPER region is multi-layered with up to 10 epithelial cell layers and cuboidal to columnar at the surface - goblet cell of the built-in lubrication system of the LID WIPER are interspersed at the surface and, as a novel finding, also within goblet cell crypts in the depth of the epithelium. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e5348cbebafbe710327ef2/1508343308678/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5873ac7e9f7456f75fb4d418/1508343105702/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589218b4f5e231783d18c344/1485969600730/ The Conjunctiva The loose connective tissue of the Lamina propria underneath the conjunctival epithelium allows a passive movement of the epithelium relative to the connective tissue and to the underlying sclera. This is necessary during eye movements and blinking as shown here, particularly during contact lens wear.. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58737eda893fc0b1a082bf17/1491411460325/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589203ea46c3c440cc7ace45/1508343094279/ The Conjunctiva A normal human CONJUNCTIVA from the nasal part with the adjacent cornea and the corneal limbus around it. The conjunctiva is basically transparent because it is a thin organ, only composed of a narrow epithelium and a mostly equally thin connective tissue lamina propria with support structures like blood vessels, nerve fibers and defense cells. Therefore the normal conjunctiva is typically only identified by its vessels that reach from the periphery towards the corneal limbus, where they stop since the cornea is avascular. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587393bdf7e0abf498547b31/1483969479907/ The Conjunctiva The CONJUNCTIVA in the tarso-orbital zone. The tarsal conjunctiva typically has a stratified two-layered cuboidal epithelium whereas that of the fornix is multilayered (see image below). In the orbital zone there is a transition. The epithelium seen here has 2-3 cell layers. Typical for this region is the large number of free bone marrow derived protective cells. They are the diffuse part of the ´Eye-Associated Lymphoid Tissue´ (EALT) that extends all along the ocular surface from the lacrimal gland, along the conjunctiva and in the lacrimal drainage system. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5892134e59cc68acbd54e66e/1491411479297/ The Conjunctiva The CONJUNCTIVA of the FORNIX has a multi-layered epithelium, which certainly contains goblet cells for production of the water-binding mucins. The cells in the surface layer are cuboidal or, as seen here, often columnar. (Mucins in the Goblet cells and on the surface are artificially colored on the photo) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e5213cbe659427c6284638/1508343297694/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7e6b8d482e94cd1ffa765/1508342984125/OSCB-Berlin.org_%28Tarsal%29-CONJUNCTIVA-and-CORNEA-are-opposed-to-each-other-in-the-conjunctival-sac_2-30_.gif The Conjunctiva The conjunctival sac is shown in a schematic diagram (left) and in a respective histological light micrograph (right) where the relatively loose structure of the conjunctiva at the back side of the eye lid can be compared to that of the opposing cornea of the eye ball on the other side. In between is KESSING´s Space - a narrow tear-filled separation of the back side of the upper eye lid from the eye ball that reduces friction between these two areas during eye movements and the blink. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5873bb30be65949ec2c64381/1508343317413/ The Conjunctiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587601ccf5e231cc324e0ae4/1484128717064/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_f%C3%BCr+BANNER%2C+STREIFEN+CONJUNCTIVA+nasal_3+ANDERER+ATW+%2BUSM_.jpg The Conjunctiva https://oscb-berlin.org/ocular-glands daily 0.75 2019-06-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58750286e6f2e1181b7f39f6/1508343618114/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874d470893fc0b2c7b252af/1508343465815/OSCB-Bild_3.2.4_Ocular+Surface_Glands+of+the+ocular+surface.png DEEPER INSIGHT into ... OCULAR GLANDS The Ocular Surface has different glands that produce different components of the tear fluid. The largest single gland that produces most of the aqueous tear fluid is the lacrimal gland in the temporal orbit. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58754c9720099e8ab04e2e17/1508343722158/ DEEPER INSIGHT into ... OCULAR GLANDS A small part of a secretory acinus from a human Meibomian gland is seen here in high magnification light microscopy. The Meibocytes mature continuously from basal cells sitting on the basement membrane ("basal") towrds the central region. The nucleus shrinks (pyknosis) whereas the cytoplasm becomes larger by production and accumulation of lipids inside large lipid droplets that can be identified as hollow spheres with some kind of peripheral wall remnants which are in far interposed organelle remnants. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874f7df29687f7cd5e85c57/1508343541412/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587561b0a5790aa4d18a0e7d/1508343648977/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58755e6237c581a46e9ede56/1508343707736/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58751500f7e0ab2e9ca9a905/1508343656758/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874e0e920099ed95c8bba6a/1508343597569/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587545fd9f7456f5135f5b4f/1508343672376/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5876189af5e231cc324ea7b7/1508343626122/ DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874dfcfc534a5d144f2f94b/1508343546991/OSCB-Bild_3.1.00_Ocular+Surface_Conjunctiva_GLANDS%2C+LACRIMAL+GLAND+Excretory+DUCT+opens+onto+the+Conjunctival+Surface.png DEEPER INSIGHT into ... OCULAR GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5874c809c534a5d144f23e50/1484048398819/OSCB-Bild_Ocular+Surface_DR%C3%9CSEN+u.+Tr%C3%A4nenTropfen+u+Tr%C3%A4nenfilm%2C+SCHEMATISCH+f%C3%BCr+BANNER+2+MEHR.png DEEPER INSIGHT into ... OCULAR GLANDS https://oscb-berlin.org/a-new-holistic-dynamic-dry-eye-concept daily 0.75 2019-06-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889d7966a49634f598d4448/1485428654289/ Dry Eye Concept 2 - INTRO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889dfd4c534a5a85e4bcb70/1485430749913/ Dry Eye Concept 2 - INTRO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889dd29b3db2b451aab1261/1485430065867/ Dry Eye Concept 2 - INTRO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889cefe59cc685fe4537f9e/1485426453194/ Dry Eye Concept 2 - INTRO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889de663e00bed8dedde8c2/1485430382227/ Dry Eye Concept 2 - INTRO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5889d2fc1b631be856f438c3/1485427467769/OSCB-GIF+3.11_HOW+to+UNDERSTAND+the+Ocular+Surface+and+Dry+Eye+Disease.gif Dry Eye Concept 2 - INTRO https://oscb-berlin.org/therapy-options-in-dry-eye-disease daily 0.75 2019-12-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3f9cef7e0abde3be0bfee/1491336513592/LINK-BILDCHEN+%28Therapie%29_CORTICOSTEROIDS.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3fa57bf629acd46e1775f/1491336592455/LINK-BILDCHEN+%28Therapie%29_LIFITEGRAST.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a17ab0e4fcb5dc18f1e1d7/1486977721359/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d78ca5790a96f919b05b/1576485379052/LINK-BILDCHEN+%28Therapie%29_Tr%C3%A4nenersatz+W%C3%84SSRIG+3.png OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e65f60414fb5affdafe5ae/1576485332984/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d46fe6f2e127ef109867/1491333274602/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e675e2d1758ef03672d746/1491498486697/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3fc8d9f7456907eac1164/1491336528144/LINK-BILDCHEN+%28Therapie%29_Inflammation+REHEARSAL.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3f8ef86e6c0ec1dcb0d55/1491336996121/LINK-BILDCHEN+%28Therapie%29_TETRACYCLINES.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d12f2994ca997dd362ce/1491325258184/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d4ffbebafb898be834f2/1491333532285/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d6e3440243062e6a9d87/1576485349373/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d26ee6f2e127ef10795d/1491332864120/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3e90b579fb30339300638/1491331639448/LINK-BILDCHEN+%28Therapie%29_ANTI-Inflammmatory+Drugs+-+Roter+Tropfen+2.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e66793a5790ab156fad648/1491497331778/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e66ee5e4fcb57652523070/1576485313180/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e667bc1b631b022ccc4700/1491497223426/LINK-BILDCHEN+%28Therapie%29_Minimizing+RISK+FACTORS+2+Bild.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d313e3df281cebcef701/1491333088014/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3dcf1bebafb898be8bc11/1491333600875/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d5028fe3df28a024a9c85f/1490354855020/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589f3086d2b857eb65ea3536/1486827675035/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3d5a003596e548662693b/1576485365255/LINK-BILDCHEN+%28Therapie%29_Tr%C3%A4nenersatz+LIPID+2.png OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3f87b197aea34f53f6276/1491336930349/LINK-BILDCHEN+%28Therapie%29_AZITHROMYCIN.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d5063d579fb37460871529/1491310928701/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3e28a725e25ad99fc7067/1491332270305/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d503092994cafbe9f1d5ff/1490354975808/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e673206b8f5b435180f5ef/1491498002186/Stratified+Approach.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3de5c29687ffa256e09d0/1491333554878/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e66148725e257204dbc00b/1576485399090/LINK-BILDCHEN+%28Therapie%29_Tear+Film+Deficiency+MANAGEMENT.JPG OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d50531bf629a6b1de61f5b/1491310936604/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d5042a5016e1bc22679f3c/1491310948206/ OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e674f9c534a58796333e54/1491498251209/Some+THERAPEUTIC+APPROACHES+for+Dry+Eye+Disease.png OVERVIEW - THERAPY 1 - Basics https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e3f96317bffcfb1f885b0f/1491336566545/LINK-BILDCHEN+%28Therapie%29_Lymphocytes+Activation+INHIBITORS.JPG OVERVIEW - THERAPY 1 - Basics https://oscb-berlin.org/glimpse-on-the-meibomian-gland-dysfunction-mgd daily 0.75 2021-05-31 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a696287131a53fb427a519/1504091017499/OSCB-Berlin.org_Meibomian-Gland-DYSFUNCTION-%28MGD%29_WEB_.gif GLIMPSE on ... MGD GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59342bb0ff7c503b73a328c9/1505832268707/OSCB-Berlin.org_LOSS+%28DROP-OUT%29+of+MEIBOMIAN+GLANDS+leads+to+Tear+Film+LIPID+DEFICIENCY+with+TrF-INSTABILITY+and+INCREASED+EVAPORATION_TrF+HELLER.png GLIMPSE on ... MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589e0680e6f2e1633c1b1346/1500053064451/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction+%28MGD%29+-+Clinical+Images+of+typical+Inspissated+Secretum+in+MGD+Patients%2C+Cornea+2010+%2B+Ophthalmologe+2009.png GLIMPSE on ... MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589e12bf6b8f5b3ad6365ae2/1500053075222/ GLIMPSE on ... MGD In NON-OBVIOUS Meibomian Gland Dysfunction (NOMGD) the lid margin appears typically quite normal (left) and this condition goes without symptoms because there is no effective deficiency of tear film lipids (yet). Only when mild pressure is applied to the lid margin in "Diagnostic Expression" it becomes obvious that no oil comes out of some Meibomian glands (middle). When strong pressure by a "Therapeutic" Expression is applied the inspissated secretum comes out of the orifices and it often has a toothpaste-like consistency (right - the redness here of the lid is due to the expression). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a69a8df14aa1f18e329398/1504090957910/OSCB-Berlin.org_MGD%2C-THERAPY-Options_LINK-Bildchen_.gif GLIMPSE on ... MGD THERAPY Options https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c12cf6bebafb21c3186ba1/1505832194709/GIF-Animation_Some-Clinical-SIGNS-in-Meibomian-Gland-Dysfunction-%28MGD%29_Einzel-BILDER_600pix-21-4_%2BOSCB.gif GLIMPSE on ... MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60b47f40e08b710458b092b2/1622441806698/OSCB-Berlin.org+%28c%29+ENK_MGD+Pathophysiology+-+Hyperkeratinisation+and+Increased+Viscosity+cause+Obstruction_20_.jpg GLIMPSE on ... MGD OVERVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589dea7e2e69cf0dd837d2f4/1500052479203/ GLIMPSE on ... MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589de79b725e25b1e0606328/1500052489046/ GLIMPSE on ... MGD A DYSFUNCTION of the Meibomian Glands (MGD) leads, due to the LIPI-DEFICIENCY of the Tear FIlm, to EVAPORATIVE DRY EYE DISEASE - which is the most frequent form that is the primary causative factor in about four fifth of Dry Eye Patients.. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59342ab0db29d6e182d594e1/1500052532504/ GLIMPSE on ... MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968fe132994ca0bae43b8ff/1505832305295/OSCB-Berlin.org_Meibomian-Gland-Dysfunction-%28MGD%29-Pathophysiology_WEB.gif GLIMPSE on ... MGD In a more focused an clinically oriented diagram, the two main PATHOGENETIC FACTORS that contribute to Meibomian Gland Dysfunction are shown together with the main CONSEQUENCES. Inspissated Meibomian Lipids, due to the occurrence of altered lipid species with increased melting point, and Hyperkeratinization of the Epithelium on the lid margin and inside the glands, can, together or alone, lead to obstruction of the Glands. The important downstream CONCEQUENCES are a (1) Lipid Deficiency on the lid margin and Tear Film with Tear Film Instability and Evaporative Dry Eye Disease. Also (2) an unnoticed pressure atrophy of the gland tissue inside the eye lids can occur due to the continuing production of oil. This leads to dilatation of the ducts and to atrophic destruction of the Secretory Meibocytes in the acini. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a699e89f8dcef77916f65a/1504090946944/OSCB-Berlinn.org_MGD---Visious-Circle-of-GLAND-DESTRUCTION_%2C-DEEPER-INSIGHT_LINK-Bildchen.gif GLIMPSE on ... MGD Deeper INSIGHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968ff8fd7bdce502107bc39/1500053400161/ GLIMPSE on ... MGD Increased Bacterial Colonization of the lid margin and conceivably also ot the Meibomian Gland appears a an important pathogenetic factor in MGD. Bacterial colonization induces, via lipid degrading bacterial enzymes, the modification of the normal Meibomian lipids into irritant species that induce a chronic sub-clincal inflammatory process that is able to induce hyper-keratinization of the epithelium as an important risk factor for obstruction that leads to consequent stasis of secretum and thus re-inforces suitable conditions for a further increase of bacterial colonization. The described pathways constitute one important vicious circle for the chronicity of MGD. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589dd338ff7c507ac48a219b/1500052511723/ GLIMPSE on ... MGD The Summary Figure of the TFOS MGD Workshop Report summarizes the main factors in the Pathophysiology of MGD - and thus explains, which pathogenetic factors contribute to the onset and worsening of MGD and how they interact in this process. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589078f81e5b6ccc19c107f9/1485863161896/OSCB-GIF_MEIBOMDR%C3%9CSE%2C+Normal+%2B+Obstruktion+%28Ophthalmologe+2009%29_LIEGT+quer%2C+CROP+oben+f%C3%BCr+Banner_20-72_2-1fps_.gif GLIMPSE on ... MGD https://oscb-berlin.org/overview-of-the-meibomian-gland-dysfunction daily 0.75 2021-08-23 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893775520099efcb0fc30af/1500052300189/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893813429687fe15fe0ff94/1500052323065/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58939d1adb29d6ce15158aa4/1505833036904/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893b2e5a5790a9b3a938569/1505833016700/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589395a586e6c0558d7e4d80/1500052276952/OSCB-Bild_2_Meibomian+Gland_Schematic+STRUCTURE+of+the+MEIBOMIAN+GLANDs+%28f%C3%BCr+Geerling+Buch+2014%29.png OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894688ce58c62299f28bd3d/1505833028707/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58946e1244024301c320e3b6/1486122527625/ OVERVIEW of ... The MEIBOMIAN GLAND Here we see Heinrich MEIBOM, the first detailed describer of the Glands that later received his name, on his probably best known portrait painting. We have added the animation of a Dancing Meibomian Gland for his and our pleasure, as he was an academic of distinction and good humor. He was Professor for Medicine, History and Poetry at the University of Helmstedt in the middle of Germany. Heinrich Meibom lived from 1638 until 1700, came from a famous academic family and had extensively travelled around in Europe during his medical study time. He described the ´Glandulae tarsales´ in the year 1666 in a publication at the University of Helmstedt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58937de7a5790a8908a9bb30/1500052330694/ OVERVIEW of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968fb8e03596e0dd8d8167f/1500052380110/ OVERVIEW of ... The MEIBOMIAN GLAND Secretory Meibocytes are arranged as a large cell clusters in dozens of ACINI in the Meibomian Glands. This schematic cell morphology of one ´differentiating´ MEIBOCYTE shows that lipid is and fills the cytoplasm. The nucleus is already reduced in volume Apart from lipid stored in lipid droplets there are mainly the organelles that are necessary for energy generation (mitochhondria) and those that are involved in lipid synthesis such as the smooth endoplasmic reticulum (sER) and large numbers of peroxysomes. Mitochhondria also contribute some synthetic steps whereas the rough endoplasmic reticulum (rER) for protein synthesis is reduces. When the Meibocyte evenntually disintegrates all these organelles form the ´Meibomian Oil´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58907619be65947e55e62e6b/1485862430141/OSCB-Bild_2_MEIBOMDR%C3%9CSE+mit+MEIBOZYTEN+sichtbar+in+ACINI+%28kommt+aus+PPT+von+%C2%B4...+ZEICHUNGEN%C2%B4%29_QUER+f%C3%BCr+BANNER+Homepage+OSCB_%2BENK%2BOSCB_KLEIN.png OVERVIEW of ... The MEIBOMIAN GLAND https://oscb-berlin.org/deeper-insight-into-the-ocular-surface-1-1 daily 0.75 2020-11-07 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2bcfc6f4ca3b9749e5366/1508340423474/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REGULATION-SYSTEMS-for-the-Ocular-Surface---The-NERVOUS-SYSTEM.gif The FUNCTIONAL UNIT - Regulatory Systems The NERVOUS SYSTEM is connected via afferent nerves (here interrupted blue lines) from the Ocular Surface and efferent fibers (here solid green lines) to the Peripheral Organs. Both fiber types have their center in the regulatory un, it of the Brain Stem of the Central Nervous System. The Nervous System performs the REGULATION of the tissue function in a neural reflex arcs via the cranial nerves V (trigeminal) and VII (facial) ... but is certainly also concerned with the Perception of Neural Sensations and of Feelings of PAIN ( - please see further down here). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2beddbce17678e712e78f/1604754671650/OSCB-Bild_7._EALT_EALT+is+the+CONTINUOUS+MUCOSAL+IMMUNE+SYSTEM+of+the+Ocular+Surface+with+RESIDENT+IMMUNE+LYMPHOID+CELLS+%2C+Chem.Imm.Allerg.+2007+.png The FUNCTIONAL UNIT - Regulatory Systems IMMUNE SYSTEM - Eye-Associated Lymphoid Tissue (EALT) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd48/1508341060495/OSCB-GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+3_18cm-72dpi_25-4fps_.gif The FUNCTIONAL UNIT - Regulatory Systems Events in Inflammatory Mucosal Disease of the Ocular Surface are influenced by Dysregulation of the Mucosal Immune System with Inflammation and Onset of a Vicious Circle (large arrow, right) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2bd4be3df28b165861506/1518891272499/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REGULATION-SYSTEMS-for-the-Ocular-Surface---The-NERVOUS-SYSTEM_LINK-Bildchen.gif The FUNCTIONAL UNIT - Regulatory Systems The NERVOUS SYSTEM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd46/1518891367585/ The FUNCTIONAL UNIT - Regulatory Systems https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd45/1508340439039/ The FUNCTIONAL UNIT - Regulatory Systems The ocular surface organs are connected via nerves to the brain stem. Neural Reflex Arcs between sensory nerves (typically trigeminal) and motor nerves (typically facial) regulate functions such as tear secretion or blinking. Here, blinking is triggered by a break-up of the tear film that leads to irritation of corneal sensory nerves. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd49/1508341074985/ The FUNCTIONAL UNIT - Regulatory Systems The mucosal immune system of the Ocular Surface (Eye-Associated Lymphoid Tissue, EALT) is an important regulatory system for the Ocular Surface because it protects the moist and nicely temperatured Ocular Surface Niche against microbial infection. Chronic irritative stimuli, however, e.g. due to environmental stimuli, can induce inflammatory mediators that may lead to chronic inflammation. This can dysregulate the Mucosal Immune System in a way that immune modulated ocular surface inflammation can result in vicious circles and drive the disease process. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5890f921bebafbb40f827bb5/1518891309845/ The FUNCTIONAL UNIT - Regulatory Systems https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a7d90dd7bdce1816a4801a/1508340457123/OSCB-Berlin.org_Ocular-Surface-%E2%80%93-Nervous-System-%E2%80%93-Sensation-%E2%80%93-PAIN.gif The FUNCTIONAL UNIT - Regulatory Systems The NERVOUS SYSTEM is connected via afferent nerves (here interrupted blue lines) from the Ocular Surface and efferent fibers (here solid green lines) to the Peripheral Organs. Both fiber types have their center in the regulatory unit of the Brain Stem of the Central Nervous System. Functions of the Nervous System are not only the REGULATION of the tissue function in a neural reflex arcs via the cranial nerves V (trigeminal) and VII (facial) but also the Perception of Neural Sensations and of Feelings of PAIN. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f7a4ec534a53e95b502a4/1508340494794/OSCB-Bild_3.0.0_Ocular+Surface_REGULATORY_ENDOCRINE+SYSTEM+-+Sex+Hormones+and+The+Ocular+Surface+.png The FUNCTIONAL UNIT - Regulatory Systems Some elements of the Endocrine Hormonal System with respect to Sex Hormones are shown here schematically. The superior centers in the hypothalamus and pituitary gland regulate dependent glands such as the Adrenal Gland and the Gonadal Glands (Ovary and Testis). The prevailing amount of sex hormones is typically produced in peripheral tissues such as in the ocular surface organs (see diagram above). At present Sex Hormones appear to have the greatest influence on the Ocular Surface but other Hormones and soluble factors may also be of importance. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd47/1508340510720/ The FUNCTIONAL UNIT - Regulatory Systems Many bone marrow derived cells, that have typically spherical and rather dark nuclei, populate the loose connective tissue of the ocular surface organs together with blood vessels and nerves (figure A). They are basically leukocytes (white blood cells) and have protective functions against different sorts of negative influences including microbes etc. Fewer leukocytes (dark nucleus in figure B) occur In the overlying layer of densely aggregated epithelial cells (epithelium) that seals the tissue against the outer environment https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa67862d9418b49127e2738/1604745324588/OSCB-Berlin.org-%28c%29-ENK_GIF-FUNCTIONAL-UNIT-Animation-TEARS-REGULATION_aus-GIF-Funct.-Unit_20-2-1_.gif The FUNCTIONAL UNIT - Regulatory Systems REGULATORY SYSTEMS are of major influence of the differentiation and function of the Ocular Surface Organs. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c2ca98f43b559df2e6075a/1518891263353/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REGULATION-SYSTEMS-for-the-Ocular-Surface-Endocrine--System---Sex-Hormonal-Part---_LINK-Bildchen.gif The FUNCTIONAL UNIT - Regulatory Systems The ENDOCRINE HORMONES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f660ce3df28cc30e69fd4/1508340379110/ The FUNCTIONAL UNIT - Regulatory Systems https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/587f63df9f74565ca916fd3e/1484044960655/OSCB-GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+3_18cm-72dpi_25-4fps_UNT+WEG+2_.gif The FUNCTIONAL UNIT - Regulatory Systems https://oscb-berlin.org/deeper-insight-into-the-conjunctiva-1 daily 0.75 2019-06-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5880dc1020099ec2c4bd3d7d/1484839967344/OSCB-Bild_3.2.3.1_Ocular+Surface_Fine+structure+of+the+ocular+epithelial+surface.png FINE STRUCTURE of the Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5880d4136b8f5b0de009688b/1483963338350/OSCB-Bild_3.2.4.3-3B_Ocular+Surface_GLYCOCYLYX+on+Conjunctival+MICROPROJECTIONS+%28COLORED+TEM%29.png FINE STRUCTURE of the Ocular Surface Micro-projections of the epithelial cells of the human ocular surface (here the conjunctiva) occur in form of finger-like microvilli and fold-like microplicae. The cell membrane that surrounds them has numerous integrated long glycoproteins (colored her in pink) that radiate into the surrounding aqueous surface milieu. The glycocalyx has a high water binding capacity and maintains the wettability of the epithelial cell surface. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a82dcbccc5c52fff12f3b6/1504194016143/Tr%C3%A4nenfilm-AQUARIUM-Animation_Einzel-BILDER_Einzel-BILDER-AUF-ZETTEL-IN-PSE-montiert_CROP_800-8-1_.gif FINE STRUCTURE of the Ocular Surface I VIEW THROUGH the TEAR FILM. The Microvilli of the epithelial cell surface with their integrated mucins can bind the water of the tears and thus make the ocular surface wettable. Free secreted mucins (faint pink lines) from the goblet cells of the conjunctiva mix with the tear water and transform it into a water-mucin-gel that forms most of the tear film thickness. A very narrow surface layer covers the aqueous phase lid a lid on a pot of warm water. It and retards the evaporation of water and thus improves the stability of the tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5880d4136b8f5b0de009688c/1508343404794/ FINE STRUCTURE of the Ocular Surface The rose peddles we see here would be considered to be "wet" by most of us because they are coverered by by water drops all over... but the are in fact not ´wetted´in the strict sense, i.e. not the complete surface is covered by water but the water is restricted to individual drops whereas most of the surface is not covered by water ... and thus remains ´dry´. So, when it comes to fine structure and molecular dimensions the issues of being ´wet´ or ´wetted´ or ´dry´ become more tricky than our conventional wisdom would assume. But ... that is the reason why we have invented ´Science´... and this is not just sophistic theory as you may notice when you develop a dry eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5880e3016b8f5b2aa42fce0e/1508343398049/ FINE STRUCTURE of the Ocular Surface Mucins form a PROTECTIVE BARRIER at the Ocular Epithelial Surface composed of the membrane bound glycocalyx (here: green) and the secreted Goblet Cell mucins (here: red). The mucin barrier prevents adherence of microbes to the cell surface. The mucin barrier has bound protective anti-microbial molecules such as the specific defense molecule Immunoglobulin A (IgA) and molecules of the non-specific innate defense systems, so called anti-microbial peptides and proteins (AMP). Together with transforms the mucin barrier into a relative in-penetrable barrier for microbes and contributes to the surprisingly low rate of infection ... in view of the fact the the ocular surface represents a moist chamber, that is almost always directly exposed to the environment. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58922db486e6c01bfffa46e9/1485974975581/OSCB-Bild_3.1.00_Ocular+Surface_Conjunctiva_FINE+STRUCTURE+Microvilli+%2B+Glycocalyx+-+PINK+RETOUCHERT_als+BANNER+2-KLEIN_3.png FINE STRUCTURE of the Ocular Surface https://oscb-berlin.org/how-dry-eye-gets-worse daily 0.75 2019-06-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894eaa8ebbd1aba555a07fa/1491560249818/ OVERVIEW - How Dry Eye GETS WORSE Tear Film Deficiency typically leads to Damage of the Ocular Surface. This occurs via Sequences of Secondary Pathogenetic Factors in the tear film dynamics that eventually lead to chronic mechanical irritation and hyper-osmolarity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ec956b8f5b3f4966a05c/1491560163928/ OVERVIEW - How Dry Eye GETS WORSE Chronic Inflammatory Pathways are a central component of the disease process of Dry Eye during Ocular Surface Tissue Damage. This is induced by the initial epithelial alterations due to tear film deficiency and may proceed into an immune-mediated mucosal inflammation, if it is not interrupted by therapeutic intervention, to a Degenerative Tissue Remodelling with Loss Of Function. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894eba259cc682d0006948e/1491560230535/ OVERVIEW - How Dry Eye GETS WORSE A primary Ocular Surface Damage can occur in certain pathologies such as in Vitamin A deficiency. Sin such cases, which are however not what we consider as a "typical" Dry Eye Disease, the Tear Film Deficiency occurs later and secondary to the Surface Damamage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ec36d2b857fb41422018/1491560153330/ OVERVIEW - How Dry Eye GETS WORSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ea4320099edad0b927e7/1491560259686/ OVERVIEW - How Dry Eye GETS WORSE The main PRIMARY Pathologies in Dry Eye Disease are Tear Film Deficiency and Ocular Surface Tissue Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894eb3ff5e231ffb74a9031/1491560239802/ OVERVIEW - How Dry Eye GETS WORSE Tear Film and and Ocular Surface Damage are closely interrelated and interdependent - in the normal physiology as well as in pathology. An intact tear film can only bind bind to an intact epithelial surface and the mucosal surface only remains intact when it is permanently kept moist by the tear fluid. In the "typical" Dry Eye Disease that the clinician sees in everyday practice Tear Film Deficiency is typically first and induces Surface Damage - whereas a primary Surface Damage is relatively rare although it may occur in certain conditions. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894f13f1b10e3996f7a3077/1491560210149/ OVERVIEW - How Dry Eye GETS WORSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ee94b3db2b05e84fe249/1491560185832/ OVERVIEW - How Dry Eye GETS WORSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ed0203596e483f630de2/1491560176234/ OVERVIEW - How Dry Eye GETS WORSE Some KEY EVENTS in chronic Ocular Surface Damage of Dry Eye Disease transform the primary protective Repair Mechanism of Sub-Clinical Inflammation into a clinically overt Destructive Chronic Mucosal Immune-Mediated Inflammation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894ef0c6a4963d1429ef71f/1491560198338/ OVERVIEW - How Dry Eye GETS WORSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e75d5f46c3c419b73efb34/1491557840356/ OVERVIEW - How Dry Eye GETS WORSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7645b1e5b6c1c76ed1d88/1491560145546/ OVERVIEW - How Dry Eye GETS WORSE https://oscb-berlin.org/how-we-get-dry-eye daily 0.75 2020-11-23 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894e85029687fbd36bb7369/1505829299227/ OVERVIEW - How we GET Dry Eye - Risk factors Meibomian Gland Dsfunction (MGD) is the main reason for a deficiency of tear film lipids. In MGD there is a quantitative deficiency of lipids on the lid margin and tear film due to the gland obstruction. At the same time there is also a qualitative deficiency of lipids because hardened, opaque lipid species of increased melting point occur, as well as irritant free fatty acids with negative influence on the lid margin tissue and on the stability of the tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589857bc3e00be25e12a63dc/1606138318951/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c1228390badedf0623e309/1505829517751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-CAUSATIVE-FACTORS-for-DRY-EYE-DISEASE-are-a-LACK-of-Tear-PRODUCTION-and-of-Tear-FILM-FORMATION%2C-Neu_auf-30%2BWEB_.gif OVERVIEW - How we GET Dry Eye - Risk factors Dysfunctions in Tear SECRETION and in Tear FILM FORMATION are the Basic Causative Factors for the onset of Dry Eye Disease because they impair the ability of the Ocular Surface to provide a permanent moist coating in all zones, including the Cornea and Conjunctiva in the opened palpebral fissure ... which typically leads to Surface Tissue Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5898552037c58185b5ed6de7/1606138304467/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b64a3dd1ae6cf4fb98c6d7c/1533322214723/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5895e5a22e69cf7fda603d0d/1606138522689/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5895f32fbe6594f5caa1318a/1606138467841/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58978b26cd0f689b9857f5fc/1505829239789/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58978b6fdb29d63750ea0e6b/1505829252402/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa69683ea796d34dee6eace/1604753043955/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_20-11-0%2C2_.gif OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894e7a959cc682d00064919/1505829292767/ OVERVIEW - How we GET Dry Eye - Risk factors The most frequent types of Dry Eye Disease are due to a deficiency of the lipid phase and of the aqueous phase. Even though the term Dry Eye Disease seems to imply that a loss of water must be more important, the main reason, according to the present data, is a primary deficiency of tear film lipids ... which can then lead to a secondary loss of water by evaporation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5898527ad482e95fd878e47e/1606138332428/ OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbbb926957a3511df670c49/1606138287213/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____MEDICATION%2C+PHARMAKA+und+Dry+Eye+Disease_20_.jpg OVERVIEW - How we GET Dry Eye - Risk factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894e933bebafb7242660d55/1505829218689/OSCB-GIF_4.5_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_20-72_25-10+GIF+-+NUR+QUER+%28links%29.gif OVERVIEW - How we GET Dry Eye - Risk factors During the Up-phase of the eye BLINK the upper lid moves over the cornea and conjunctiva spreads a new thin pre-ocular tear film over the bulbar surface. Impairments of blinking impair the quantity of quality - when frequency of blinking, or the fullness of a blink (partial blink) or the formation of a tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5898463286e6c0c6ce7deab1/1606138345639/ OVERVIEW - How we GET Dry Eye - Risk factors https://oscb-berlin.org/overview-neu daily 0.75 2019-06-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5887969337c581ac2ceaeea9/1505830553155/OSCB-Bild_3_Ocular+Surface_MAIN+FUNCTIONAL+COMPLEXES+of+the+Ocular+Surface.png OVERVIEW on ... DRY EYE DISEASE Dry Eye Disease is a prototypic Ocular Surface Disease because it is based on a deficiency of Moisture - which is the most basic function of the Ocular Surface. Moisture is the pre-requisite for Ocular Surface Health and thus for the establishment and maintenance of vision ... as explained in the Ocular Surface Section. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5887b7a417bffc064b7d34a5/1504541762939/ OVERVIEW on ... DRY EYE DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588a559b5016e137992d6913/1504541775856/ OVERVIEW on ... DRY EYE DISEASE The Intact Function of the Eye Lids for BLINKING is necessary to transform a sufficient volume and quality of secretion by the Ocular Surface Glands into a Tear FILM. This is required for permanent moisture for maintenance of the integrity of the ocular surface tissue and certainly also necessary for refraction of light in order to provide perfect vision. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888ad66ff7c503f7f15646a/1504540663564/ OVERVIEW on ... DRY EYE DISEASE Tear Film and and Ocular Surface Damage are closely interrelated and interdependent - in the normal physiology as well as in pathology. An intact tear film can only bind bind to an intact epithelial surface and the mucosal surface only remains intact when it is permanently kept moist by the tear fluid. In the "typical" Dry Eye Disease that the clinician sees in everyday practice Tear Film Deficiency is typically first and induces Surface Damage - whereas a primary Surface Damage is relatively rare although it may occur in certain conditions. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58878c47a5790a35ff7bfe0e/1485278302713/ OVERVIEW on ... DRY EYE DISEASE Some clinical images of patients with Dry Eye Disease - the disease severity increases from left to right including increasing alterations of the lid margin with pouting of Meibomian gland orifices, inflammation, lid margin rounding and irregularity, with loss of eye lashes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588889b0d1758ecbedcf5415/1485343160225/ OVERVIEW on ... DRY EYE DISEASE During the eye BLINK the upper lid moves over the cornea and conjunctiva. In the down-phase the ´old´tear film is compressed and in the up-phase a new thin pre-ocular tear film is spread over the bulbar surface. This schematic drawing greatly exaggerates the thickness of the tear film in order to make it visible at this enlargement. The tear film thickness is presently found to be typically under the height of one conjunctival epithelial cell. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5887a8d415d5dbf26a3e4ac7/1504540641657/ OVERVIEW on ... DRY EYE DISEASE The most frequent types of Dry Eye Disease are due to a deficiency of the lipid phase and of the aqueous phase. Even though the term Dry Eye Disease seems to imply that a loss of water must be more important, the main reason, according to the present data, is a primary deficiency of tear film lipids. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588f18732e69cf76b764b6e6/1485772926092/ OVERVIEW on ... DRY EYE DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588f1c96e4fcb5a6cdd1ccc2/1485773983994/OSCB-Bild_6.0_Dry+Eye+Disease_Chronic+INFLAMMATORY+Pathways+are+a+central+component+of+OCULAR+SURFACE+DAMAGE+in+DRY+EYE+Disease.png OVERVIEW on ... DRY EYE DISEASE Chronic Inflammatory Pathways are a central component of the disease process of Dry Eye during Ocular Surface Tissue Damage. This is induced by the initial epithelial alterations due to tear film deficiency and may proceed into an immune-mediated mucosal inflammation, if it is not interrupted by therapeutic intervention, to a Degenerative Tissue Remodelling with Loss Of Function. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888cb0a3e00be3ae99dce57/1485359888780/OSCB-Bild_6_Dry+Eye+Disease_PATHOLOGY+in+DRY+EYE+DISEASE+...+Sequences+of+Secondary+Pathogenetic+Factors+lead+to+SURFACE+DAMAGE.png OVERVIEW on ... DRY EYE DISEASE Tear Film Deficiency typically leads to Damage of the Ocular Surface. This occurs via Sequences of Secondary Pathogenetic Factors in the tear film dynamics that eventually lead to chronic mechanical irritation and hyper-osmolarity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5887b72bbe6594b0eb7a8346/1485289270836/ OVERVIEW on ... DRY EYE DISEASE Dysfunctions in Tear SECRETION and in Tear FILM FORMATION are the Basic Causative Factors for the onset of Dry Eye Disease because they impair the ability of the Ocular Surface to provide a permanent moist coating in all zones, including the Cornea and Conjunctiva in the opened palpebral fissure ... which typically leads to Surface Tissue Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5887b873ff7c50e61645c993/1504540628729/ OVERVIEW on ... DRY EYE DISEASE Meibomian Gland Dsfunction (MGD) is the main reason for a deficiency of tear film lipids. In MGD there is a quantitative deficiency of lipids on the lid margin and tear film due to the gland obstruction. At the same time there is also a qualitative deficiency of lipids because hardened, opaque lipid species of increased melting point occur, as well as irritant free fatty acids with negative influence on the lid margin tissue and on the stability of the tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588916fbdb29d6cc6c34c77e/1485379334985/ OVERVIEW on ... DRY EYE DISEASE Some KEY EVENTS in chronic Ocular Surface Damage of Dry Eye Disease transform the primary protective Repair Mechanism of Sub-Clinical Inflammation into a clinically overt Destructive Chronic Mucosal Immune-Mediated Inflammation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588f1ae5cd0f68ca7cf78d15/1485773587404/ OVERVIEW on ... DRY EYE DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888cb5129687fe9465c7c14/1504541754228/OSCB-Bild_6_Dry+Eye+Disease_PATHOLOGY+in+DRY+EYE+DISEASE+...+Sequences+of+Secondary+Pathogenetic+Factors+lead+to+SURFACE+DAMAGE.png OVERVIEW on ... DRY EYE DISEASE The main PRIMARY Pathologies in Dry Eye Disease are Tear Film Deficiency and Ocular Surface Tissue Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888c10fc534a55f1f73ff16/1485357332532/ OVERVIEW on ... DRY EYE DISEASE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888b6094402431db0e1dd0d/1485354515886/ OVERVIEW on ... DRY EYE DISEASE A primary Ocular Surface Damage can occur in certain pathologies such as in Vitamin A deficiency. Sin such cases, which are however not what we consider as a "typical" Dry Eye Disease, the Tear Film Deficiency occurs later and secondary to the Surface Damamage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5888b1d7cd0f68fe532a5627/1485353445136/ OVERVIEW on ... DRY EYE DISEASE https://oscb-berlin.org/what-is-dry-eye- daily 0.75 2019-06-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a36626ff7c503db487fb61/1487103537758/ OVERVIEW - WHAT is DRY EYE ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a368bd17bffc153c6645b7/1487104199984/ OVERVIEW - WHAT is DRY EYE ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894e57cbf629a3e30c712f6/1486153101866/ OVERVIEW - WHAT is DRY EYE ? Some clinical images of patients with Dry Eye Disease - the disease severity increases from left to right including increasing alterations of the lid margin with pouting of Meibomian gland orifices, inflammation, lid margin rounding and irregularity, with loss of eye lashes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594fd857f7e0ab73b6a80c9f/1498404967480/ OVERVIEW - WHAT is DRY EYE ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a365d903596e0fdbacb128/1487103461048/OSCB-Bild_3.1.0_Ocular+Surface_FUNCTIONAL+UNIT+auf+Dry+Eye+CONCEPT+Layout_F%C3%9CR+GIF+1v2_18cm-72dpi_.png OVERVIEW - WHAT is DRY EYE ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894e63bbf629a3e30c726bb/1486153282247/ OVERVIEW - WHAT is DRY EYE ? https://oscb-berlin.org/deeper-insight-into-new-dry-eye-concept daily 0.75 2017-06-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b20bfa5790a7a1f5cc728/1485512900000/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b5969197aea20429c5223/1485527408668/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588a5bbfe58c626bb864bf13/1485462483398/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b243c9f7456789fc140f5/1485513814550/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b41b72994ca9f398494f9/1485521344968/OSCB-GIF_V.4B_TRAGEDY+2+of+Dry+Eye+Disease+-CAUSATIVE+Factors+cause+PRIMARY+PATHOLOGY_25cm-72_4-0.2fps_.gif Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b417744024328bf0736f7/1485521301043/OSCB-GIF_V.4B_TRAGEDY+of+Dry+Eye+Disease_25cm-72_14-0.5fps_.gif Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b233ecd0f6809c6ded14a/1485513548828/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b58d944024328bf0802c4/1485527267417/ Dry Eye Concept 5 - BASICS on Function & Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588b271586e6c024ec096a8c/1485514529459/ Dry Eye Concept 5 - BASICS on Function & Disease A simplified scheme of the nervous system in relation to the Ocular Surface. The cranial nerves V (trigeminal) and VII (facial) maintain the reflex arcs that drive the regulation of secretion by the ocular glands and of the lid apparatus for blinking. https://oscb-berlin.org/deeper-insight-into-new-dry-eye-concept-1 daily 0.75 2017-01-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358618/1485528662656/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT Sequences of Secondary Pathogenetic Factors govern the primary pathology of Tear Film Deficiency - and interact with each other. The secondary pathology terminates in Chronic Mechanical Irritation by Friction and Hyper-Osmolarity as the main factors that induce Damage of the Surface Tissue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358621/1485624027045/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35861b/1485595401581/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT A schematic mechanistic diagram shows some KEY EVENTS in Mucosal Inflammation during Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec35861f/1485693952098/OSCB-Bild_6.0_Dry+Eye+Disease_TYPEs+of+Dry+Eye+and+Tear+Film+Deficiency+in+Dry+Eye+Disease.png RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358628/1485637392653/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35860d/1485456011646/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35860f/1485513548828/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358619/1485603306068/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT The Different Types of Tear Film Deficiency that determine the Type of Dry Eye Disease tend to mix with increasing severity of disease. This is conceivably due to the impairment of more and more functional complexes with downstream negative effects as the disease process proceeds, destroys for tissues and becomes more severe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358623/1485632353308/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358614/1485521344968/OSCB-GIF_V.4B_TRAGEDY+2+of+Dry+Eye+Disease+-CAUSATIVE+Factors+cause+PRIMARY+PATHOLOGY_25cm-72_4-0.2fps_.gif RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358627/1485614213374/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT Pathological Carousels of Gland Dysregulation link the pathology in the glands and at the "surface" of cornea and conjunctiva in a mighty Vicious Circle. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358610/1485512900000/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358626/1485629367669/OSCB-Bild_6.0_Dry+Eye+Disease_MGD_MGD-PATHOPHYSIOLOGY+LIDRAND-Schema+-+%C3%9CBERARBEITET%2C+Ophthhalmologe+2009+.png RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358617/1485526468379/OSCB-Bild_DRY+EYE+HIERARCHY+of+Causative+Facors+cause+Primary+Patholology+governed+by+Sequences+of+Secondary+Pathogenetic+Factors+_Folie59_25cm-72dpi.jpg RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35861c/1485599871610/OSCB-BILD_6_Dry+Eye+Disease_VERSCHIEDENE+VICIOUS+CIRCLES++in+Dry+Eye+von+UNS+VORGESTELLT+SEIT+2000_.png RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358620/1485624229992/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358615/1485527408668/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358613/1485521301043/OSCB-GIF_V.4B_TRAGEDY+of+Dry+Eye+Disease_25cm-72_14-0.5fps_.gif RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358622/1485610263554/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT A vicious circle that does not primarily depend on inflammation closely links an interrelates Tear Film Deficiency and Ocular Surface Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35860e/1485462483398/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358612/1485514529459/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT A simplified scheme of the nervous system in relation to the Ocular Surface. The cranial nerves V (trigeminal) and VII (facial) maintain the reflex arcs that drive the regulation of secretion by the ocular glands and of the lid apparatus for blinking. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec35861e/1485614953650/OSCB-BILD_VICIOUS+CIRCLES+3_Folie92_25cm-72dpi.jpg RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358624/1485626168758/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT A major concept for aqueous tear deficiency in Dry Eye Disease is an afferent sensory nerve fiber impairment due to chronic inflammatory processes at the bulbar surface (cornea and conjunctiva) in dry eye disease. Dysfunction of the afferent sensory nerves will lead to a dysfunction of the neural reflex arc for driving the efferent innervation for secretion of the lacrimal gland. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358611/1485513814550/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c1d2b857b6ec358625/1485626878306/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec358616/1485527267417/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35860c/1485455484380/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35861a/1485531844704/ RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT Secondary Pathogenetic Factors in SURFACE Tissue DAMAGE also form Sequences of increasing severity that propagate the disease process. Chronic inflammation is the main amplifier of disease - it gives rise to several Vicious Circles and to a Chronic Tissue Remodeling with Loss of Function. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e02c0d2b857b6ec35861d/1485539617354/OSCB-BILD_Dry+Eye+Disease_VISCIOUS+CIRCLES+-+Schema_Folie86_25cm-72dpi.jpg RESERVE__DEEPER INSIGHT ... into DRY EYE CONCEPT https://oscb-berlin.org/dry-eye-concept-2-bascis daily 0.75 2017-02-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e076d6a4963c410034572/1485703066477/ Dry Eye Concept 3 - HOW to understand ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e081603596e0fcbc3b0c3/1485703197621/ Dry Eye Concept 3 - HOW to understand ? https://oscb-berlin.org/deeper-insight-into-new-dry-eye-concept-2 daily 0.75 2017-05-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1aa15016e177f546b4bb/1485528662656/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors Sequences of Secondary Pathogenetic Factors govern the primary pathology of Tear Film Deficiency - and interact with each other. The secondary pathology terminates in Chronic Mechanical Irritation by Friction and Hyper-Osmolarity as the main factors that induce Damage of the Surface Tissue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1aa15016e177f546b4ba/1485526468379/OSCB-Bild_DRY+EYE+HIERARCHY+of+Causative+Facors+cause+Primary+Patholology+governed+by+Sequences+of+Secondary+Pathogenetic+Factors+_Folie59_25cm-72dpi.jpg Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1ff2d482e988fc0b1641/1485709305627/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1aa15016e177f546b4bd/1485531844704/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors Secondary Pathogenetic Factors in SURFACE Tissue DAMAGE also form Sequences of increasing severity that propagate the disease process. Chronic inflammation is the main amplifier of disease - it gives rise to several Vicious Circles and to a Chronic Tissue Remodeling with Loss of Function. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1aa15016e177f546b4bc/1485603306068/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors This very schematical diagram is supposed to indicate that the Different Types of Tear Film Deficiency that determine the Type of Dry Eye Disease tend to mix with increasing severity of disease. This is conceivably due to the impairment of more and more functional complexes with downstream negative effects as the disease process proceeds, destroys for tissues and becomes more severe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e1aa15016e177f546b4be/1485595401581/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors A schematic mechanistic diagram shows some KEY EVENTS in Mucosal Inflammation during Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e204303596e0fcbc494c0/1485709386529/ Dry Eye Concept 6 - HIERARCHY of Pathogenetic Factors https://oscb-berlin.org/dry-eye-concept-5-vicious-circles daily 0.75 2017-05-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a9a/1485637392653/ Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a96/1485626168758/ Dry Eye Concept 7 - VICIOUS CIRCLES A major concept for aqueous tear deficiency in Dry Eye Disease is an afferent sensory nerve fiber impairment due to chronic inflammatory processes at the bulbar surface (cornea and conjunctiva) in dry eye disease. Dysfunction of the afferent sensory nerves will lead to a dysfunction of the neural reflex arc for driving the efferent innervation for secretion of the lacrimal gland. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a98/1485629367669/OSCB-Bild_6.0_Dry+Eye+Disease_MGD_MGD-PATHOPHYSIOLOGY+LIDRAND-Schema+-+%C3%9CBERARBEITET%2C+Ophthhalmologe+2009+.png Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a92/1485624229992/ Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a97/1485626878306/ Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a90/1485614953650/OSCB-BILD_VICIOUS+CIRCLES+3_Folie92_25cm-72dpi.jpg Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e3caa2e69cf76b75b8742/1485716669529/ Dry Eye Concept 7 - VICIOUS CIRCLES A vicious circle that does not primarily depend on inflammation closely links an interrelates Tear Film Deficiency and Ocular Surface Damage. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a91/1485693952098/OSCB-Bild_6.0_Dry+Eye+Disease_TYPEs+of+Dry+Eye+and+Tear+Film+Deficiency+in+Dry+Eye+Disease.png Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a99/1485614213374/ Dry Eye Concept 7 - VICIOUS CIRCLES Pathological Carousels of Gland Dysregulation link the pathology in the glands and at the "surface" of cornea and conjunctiva in a mighty Vicious Circle. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a8e/1485599871610/OSCB-BILD_6_Dry+Eye+Disease_VERSCHIEDENE+VICIOUS+CIRCLES++in+Dry+Eye+von+UNS+VORGESTELLT+SEIT+2000_.png Dry Eye Concept 7 - VICIOUS CIRCLES VICIOUS CIRCLES are not new in Dry Eye Disease and Members of the Ocular Surface Center Berlin (OSCB) have frequently suggested Vicious Circles in Concepts for Dry Eye Disease in various publications. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a8f/1485539617354/OSCB-BILD_Dry+Eye+Disease_VISCIOUS+CIRCLES+-+Schema_Folie86_25cm-72dpi.jpg Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a95/1485632353308/ Dry Eye Concept 7 - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/588e2b8fbf629abc01dd0a93/1485624027045/ Dry Eye Concept 7 - VICIOUS CIRCLES https://oscb-berlin.org/a-new-holistic-dynamic-dry-eye-concept-1 daily 0.75 2019-06-18 https://oscb-berlin.org/new-page-4 daily 0.75 2017-02-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f682c6a4963c410120a5b/1485793328351/Folie113_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f682c2994ca61598a3be2/1485793326842/Folie112_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f682b197aeae36a728616/1485793324830/Folie111_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6829d2b857b6ec4447d7/1485793323345/Folie110_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6829bf629abc01ea35c4/1485793323753/Folie109_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68271b10e309aef914ee/1485793322319/Folie108_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68271e5b6c3aa814eaf8/1485793321713/Folie107_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6823f5e231b9aa6131b6/1485793317722/Folie106_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6821ebbd1aab3fc46ba4/1485793315197/Folie105_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68216a4963c4101209cf/1485793317087/Folie104_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f681c29687f77161ab50f/1485793310110/Folie103_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f681bbe6594f32865687f/1485793310039/Folie102_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68156b8f5b152886a15d/1485793303286/Folie101_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6814725e2506f4c23cfb/1485793303955/Folie100_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f680ed1758e87f0711c69/1485793296030/Folie99_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f680e17bffc6e425a4d5b/1485793295912/Folie98_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f680cbf629abc01ea3363/1485793295462/Folie97_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f680c2994ca61598a3986/1485793293684/Folie96_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68073a0411d31b55dbcf/1485793289403/Folie95_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68073e00be6360b2fecf/1485793289681/Folie94_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6804440243895c577473/1485793285574/Folie93_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f680303596e0fcbd21a38/1485793291329/Folie92_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6802e3df287fa745874e/1485793283443/Folie91_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68015016e177f5549156/1485793283653/Folie90_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f68006b8f5b152886a038/1485793281852/Folie89_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67fc1b10e309aef911dc/1485793277878/Folie88_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67fbbebafb21326d23b2/1485793277910/Folie87_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67f915d5db7dfec4b37b/1485793274330/Folie86_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67f8b8a79b901b6f5d6d/1485793273702/Folie85_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67f717bffc6e425a4c3a/1485793272925/Folie84_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67f21b10e309aef91145/1485793269079/Folie83_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67f2e58c62276f79ba2a/1485793269453/Folie82_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67eebe6594f3286565a7/1485793264505/Folie81_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67ed03596e0fcbd218c6/1485793263218/Folie80_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67eb579fb35be4040575/1485793262094/Folie79_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67ea3e00be6360b2fd18/1485793259267/Folie78_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e7cd0f68ca7cfaa7a4/1485793256974/Folie77_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e7c534a52f773c9662/1485793257132/Folie76_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e6f5e231b9aa612d8f/1485793255434/Folie75_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e56b8f5b1528869e57/1485793255190/Folie74_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e23e00be6360b2fc6d/1485793251898/Folie73_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67e15016e177f5548f6a/1485793252137/Folie72_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67ded482e988fc18adce/1485793249006/Folie71_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67de414fb55621e89dff/1485793249368/Folie70_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67db46c3c4023d9432b1/1485793245024/Folie69_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67da6a4963c410120540/1485793243155/Folie68_25cm-72dpi.jpg Dry Eye Concept 4 - 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NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6799ebbd1aab3fc4628f/1485793179025/Folie07_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67996a4963c410120132/1485793179188/Folie06_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6798bf629abc01ea2c1c/1485793180880/Folie05_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6797c534a52f773c90eb/1485793176534/Folie04_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f6796bf629abc01ea2c14/1485793177128/Folie03_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67955016e177f5548aa5/1485793174603/Folie02_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/588f67832994ca61598a313f/588f67948419c2ec3fea1a48/1485793174986/Folie01_25cm-72dpi.jpg Dry Eye Concept 4 - NEW CONCEPT https://oscb-berlin.org/overview-of-the-meibomian-gland-dysfunction-1 daily 0.75 2020-11-07 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968f89cf14aa14e4beffcbb/1604770062089/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5890a47915d5db10dc63a9ca/1485874308836/OSCB-Bild_2_MEIBOMDR%C3%9CSE_The+Meibomian+OIL+functions+for+retarding+evaporation+and+for+optimal+light+Refraction_.png GLIMPSE of ... The MEIBOMIAN GLAND The main functions, among probably many others, are the retardation of evaporation of the aqueous phase, the water of the tear film, by sealing the tear film like a lid on a pot of warm water. A second important function is to provide a very smooth and homogeneous surface for the air-to-tear interface that is the main refractory surface of the eye. It provides about 3/4 of the refractive power of the eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/593309b06b8f5b7626ebe73d/1496517409769/OSCB-Berlin.org_The+MEIBOMIAN+GLAND+LIPIDS+form+an+OIL+at+room+temperature+that+is+delivered+via+the+orifice+onto+the+lid+margin_PHOTO+courtesy+of+DONALD+KORB.png GLIMPSE of ... The MEIBOMIAN GLAND Healthy Meibomian Glands deliver a clear liquid oil (arrow) through their orifice onto the lid margin. This can be tested by a technique termed ´Diagnostic Expression´ with very mild pressure from the outside - every orifice should then deliver a little puddle of oil (arrow). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a68a34e6f2e1da6ae08449/1504086596610/Animation_ONLY-A-THIN-HOMOGENEOUS-TEAR-FILM-guarantees-HEALTH-and-clear-VISION_8-2_.gif GLIMPSE of ... The MEIBOMIAN GLAND The Tear Film in front of the transparent cornea (the pre-corneal tear film) is a layered structure in which typically three layers are discriminated: (1) at the outside surface to the ambient air is, as just explained in the text to the left, the thin layer of Meibomian Oil (yellow). The oil covers (2) the aqueous main phase of the tear film that is conceivably to some extent mixed with Mucins that constitute in a concentrated for the (3) inner Mucin (pink) Layer that is locate directly on and produced by the cells of the surface epithelium of the ocular surface. The thin lipid layer on top is in the schematic drawing shown much too broad - because, in the real size relation, it would be almost impossible to see it in cross section through a tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58908c051b631bae05850fe2/1604770031818/ GLIMPSE of ... The MEIBOMIAN GLAND The extended long gland bodies of the MEIBOMIAN GLANDS can be seen through the conjunctiva when the eye lid (here the lower one) is slightly everted. The individual orifices (indicated here by open arrows) are typically arranged in a single row, very close to the posterior lid border - immediately in front of the anterior rim of the tear meniscus. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968f7a0725e258b0639da53/1604770052845/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589f09a03e00be6bfe542746/1486817715104/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5894617217bffcb23cad7f80/1486119292074/OSCB-Bild_2_Meibomian+Gland_Schematic+STRUCTURE%2C+NORMAL+vs.+OBSTRUCTED+%28kurz%29+aus+Ophthalmologe+2009.png GLIMPSE of ... The MEIBOMIAN GLAND In an obstructed gland (right) the delivery of the secreted oil is blocked and therefore the increasing pressure inside the gland leads to a dilatation of the ducts and to a pressure atrophy of the secretory acini. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5932fe79ebbd1a5080ec6dda/1496514215776/OSCB-Berlin.org_2_MEIBOMDR%C3%9CSE_The+MEIBOMIAN+GLANDS+in+the+Eye+Lids+produce+LIPIDS+for+the+Tear+Film+%28Zeichnung%2BFoto%29_3+mit+%C3%96L-Schicht.png GLIMPSE of ... The MEIBOMIAN GLAND The Oil from the Meibomian Glands inside the Eye Lids covers the aqueous Tear FILM with an oily layer that retards evaporation of water and increases the stability of the tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590783de6a4963cec490ccfe/593314a0c534a56c194f7b07/1496520996778/MEIBOMDr%C3%BCse_Eigene+ZEICHNUNG+%2B+FOTO+Augenoberfl%C3%A4che+eigene.jpg GLIMPSE of ... The MEIBOMIAN GLAND - GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590783de6a4963cec490ccfe/590786dc1e5b6c7f60acdd26/1493665680221/OSCB-GIF_MEIBOM+DANCING+%26+OSCB-Berlin%2C+ENK_15cm-72_3-1.5fps_.gif GLIMPSE of ... The MEIBOMIAN GLAND - HISTORY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/590783de6a4963cec490ccfe/5907864b197aea19727986ff/1493665485689/OSCB-Bild_2_Meibomian+Gland_Histology+of+the+Meibomian+Gland+ACINUS%2C+Neu+-+QUER.png GLIMPSE of ... The MEIBOMIAN GLAND - OVERVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968fa5446c3c428c0441efa/1604770073218/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589081a2a5790a3763180d30/1604770044899/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968f6d559cc684cdcfbcb5f/1500051170747/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968f7f7bf629a14d6590fd8/1500051457122/ GLIMPSE of ... The MEIBOMIAN GLAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58907e771b631bae05849bc4/1485864580335/MEIBOMDR%C3%9CSE%2C+Normal+%28EIGENE+Zeichnung+Ophthalmologe+2009%29_LIEGT+quer+f%C3%BCr+BANNER+f%C3%BCr+OSCB+Homepage_20cm-72_%2BENK%2BOSCB%2C+Sauber%2BSCHMALER_.png GLIMPSE of ... The MEIBOMIAN GLAND https://oscb-berlin.org/images-for-teaching daily 0.75 2017-09-20 https://oscb-berlin.org/overview-of-the-meibomian-gland-dysfunction-2 daily 0.75 2019-06-14 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893a2b517bffcb23ca5765f/1485984448708/OSCB-BILD_2_MEIBOMDR%C3%9CSE+im+Lid%2C+3D+Zeichnung+KRSTIC%2C+%2BVERFREMDET+stark+%2B+DOPPELSCHATTEN+%2B+SPIEGELUNG+%2B+Zugeschnitten.png HISTORY of ... The MEIBOMIAN GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893a2b517bffcb23ca57661/1486054804514/ HISTORY of ... The MEIBOMIAN GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5893a2b517bffcb23ca57660/1486054388755/ HISTORY of ... The MEIBOMIAN GLANDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589485081b10e322367e492c/1486128399229/HEINRICH+MEIBOM%2C+PORTRAIT+a.s+BANNER_3+HELLER.png HISTORY of ... The MEIBOMIAN GLANDS https://oscb-berlin.org/deeper-insight-into-mgd-vicious-circles daily 0.75 2019-06-14 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589eeddd1b631bc1785596eb/1505833870717/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c1324c18b27d8be7d26425/1505833568798/OSCB-Berlin.org_%28Tarsal%29-CONJUNCTIVA-and-CORNEA-are-opposed-to-each-other-in-the-conjunctival-sac_2-30_.gif DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES The tarsal plate with the included Meibomian Glands is in immediate vicinity of the conjunctiva - directly underneath the narrow connective tissue of the conjunctival lamina propria and only about 0,1mm from the lumen of the conjunctival sac. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59343d9ee4fcb549ee8a8f58/1505833461696/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES Commensal Bacterial Species occur on the normal lid margin and have also been found inside freshly expressed Meibomian secretum. In pathological conditions of the Meibomian Gland the bacteria increase in number - which is termed increased ´colonization´ and does not represent an ´ínfection´. The bacteria produce enzymes that degrade the normal Meibomian lipids and induce formation of lipids that are irritant to the cells, with downstream activation of inflammatory mediators, and also to the tear film that becomes unstable. This leads to the onset of an inflammatory vicious circle that promotes important pathogenetic factors in MGD such as hyper-keratinization, obstruction and stasis of lipids inside the gland ... which again reinforces bacterial growth. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589eee2dd482e9cad930492a/1505833864818/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589eec07c534a53dfb39cda9/1486810133025/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c133602994ca95aeb10ecb/1505833841292/OSCB-Bild_2_Meibomian-Gland_MGD-PATHOPHYSIOLOGY_NEGATIVE-Influence-Factors-on-the-Meibomian-Gland-lead-to-Gland-DROP-OUT-3_WEB_.gif DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES Negative Influence factors such as Contact Lenses and Inflammatory Conjunctival Disease (Allergic Conjunctivitis) lead to a destruction of the Meibomian Glands. This is detectable as visible Drop-Out of Gland Tissue in Meibography (bottom right, schematic representation) that constitute MGD, and by clinical Tear Film Deficiency that constitutes Dry Eye Disease. (Slit lamp Photo: Courtesy of Uwe Pleyer). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589ee68e893fc0b6d3ca8ba7/1505833453870/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES The Summary Figure for the TFOS MGD Report was prepared by Members of the Ocular Surface Center Berlin (OSCB) and summarizes important pathogenetic factors in one diagram that is intuitively understandable. The main pathogenetic factors are Hyperkeratinization of the epithelium together with Increased Viscosity of the Secretum that can result, together or alone, in Meibomian Gland Obstruction. Further factors of importance, as well as their interaction ... are explained in the text to the left side of this diagram. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/589eea88e4fcb5dc18db1266/1505833478449/ DEEPER INSIGHT into ... MGD - VICIOUS CIRCLES https://oscb-berlin.org/therapy-options-in-dry-eye-disease-1-1 daily 0.75 2020-05-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58baaa7515d5db6536fea12b/1576483252367/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab27d9f5e231309140f5cc/1576483252383/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a09e311b10e3f74fabc654/1486921274067/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58baaa45cd0f68842cbac64b/1576483252370/ Deeper Insight THERAPY 3 - Tear Supplementation Individual Hyaluronic Acid (HA) molecules with lots of bound water molecules are seen in the left image. On the right side the loose connective tissue of the Conjunctival Lamina propria is shown - where HA acts as a spacer between the collagen fibers (grey) and HA thus provides a certain elasticity to the tissue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5918706a15cf7d45e96da9f3/1576483252375/OSCB-Berlin.org_Augenoberfl%C3%A4che_Ocular+Surface+for+HA+High+Viscosity+vs.+Low+Viscosity.png Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a1b7983a0411d59c72d404/1576483252358/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a0735c8419c22b6efdb83b/1486910309616/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e62deccd0f6881c97d0e85/1576483252349/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58b9a018197aea8f21c2f94e/1576483252355/ Deeper Insight THERAPY 3 - Tear Supplementation ... two sides of the same coin show that the MANAGEMENT OF TEARS and their deficiency, respectively, at the Ocular Surface can dissected into different steps which are: (1) The STIMULATION of natural tear flow by secretagogues, (2) the SUPPLEMENTATION of tear components either as individual components such as e.g. just lipids, or as a kind of complete solution as "Artificial Tears", and (3) the RETENTION time of the tear fluid at the Bulbar Surface before they disappear and drain into the lacrimal drainage system ... which also is a part of the Ocular Surface but can no longer keep the cornea and conjunctiva moist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5918d25fa5790ae3f68610ce/1576483252372/Bild1OSCB-Berlin.org_Hyaluronic+Acid+%28HA%29+Non-Newtonian+Behaviour%2C+Open+Eye+vs.+Blinking.png Deeper Insight THERAPY 3 - Tear Supplementation Hyaluronic Acid has aspects of Non-Newtonian abilities like the natural tears with lower viscosity during eye blinks (Images courtesy of TRB Chemedica) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58b99f541e5b6cb3b1280fba/1576483252352/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a0becb86e6c01db8f8e62a/1486929632268/OSCB-GIF_LIDER+%28FRONTAL%29+Animation+%28ENK%29+BLINZELN_%28aus+KL+Weich%29_NEU+MAN.+Verschob_OHNE+OSCB_mit+LIPIDSPRAY+Vollformat_25-8fps_.gif Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e525ffd482e9f89253a17d/1576483252392/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59186e2fd1758edfb7d43327/1576483252378/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5919d524e3df28cc1106e338/1576483252400/OSCB-Berlin.org_P2Y2+Receptors+on+Ocular+SECRETORY+TISSUES+allow+to+target+Increased+Tear+Secretion+by+P2Y2+AGONISTS+%28Diquafosol%29.png Deeper Insight THERAPY 3 - Tear Supplementation Secretagogues that stimulate the P2Y2 Receptor on ocular Secretory Tissues allow to target an increased secretion of tear components and thus an increase of tear fluid volume on the ocular surface. An example of this class of tear supplementation drugs is the P2Y2 agonist Diquafosol from Santen Pharma, which is however only available in Asia. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a073d646c3c41632fb01c2/1486910432167/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a1bd10e4fcb5dc18f3bbe5/1576483252341/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a04efbd2b857eb65f39ef9/1484571113270/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5919d85415cf7d45e97c5d47/1576483252398/ Deeper Insight THERAPY 3 - Tear Supplementation Secretory cells of several Ocular Surface Tissues, as shown here in a schematic drawing, are equipped with cell membrane receptors for the agonist P2Y2 that allows a regulation of secretion https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab2b5544024386af7d2976/1576483252389/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e61e89be65941323e78ed6/1576483252346/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+-+MAIN+CAUSATIVE+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png Deeper Insight THERAPY 3 - Tear Supplementation The BASIC CAUSATIVE FACTORS for Dry Eye Disease are a Deficiency of Tear SECRETION and/or of Tear FILM FORMATION because this impairs to keep the ocular surface moist everywhere &every-time and impair perfect visual acuity. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab2f18d1758e84118f1aa8/1576483252386/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a1a561f5e231ba9d0c43ac/1576483252361/ Deeper Insight THERAPY 3 - Tear Supplementation With increasing destruction of tissues and regulatory systems in moderate to severe Dry Eye Disease the primary types of tear film deficiency tend to mix because the ocular surface becomes increasingly dysregulated. A main concept for aqueous tear deficiency is based on such dysregulation that occurs when the afferent sensory innervation at the ocular surface proper, cornea and conjunctiva is impaired and thus the neural reflex arc for tear secretion is altered resulting in lower aqueous secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab1d0c6b8f5bc508289570/1576483252344/ Deeper Insight THERAPY 3 - Tear Supplementation There are at least two main types of Dry Eye that both lead to a low tear volume but have a different pathophysiology background and thus different therapeutical approaches. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bab74f414fb53851203a3a/1576483252338/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ba9b47414fb538511fac4f/1576483252381/ Deeper Insight THERAPY 3 - Tear Supplementation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58baa0b6f5e23191658081f3/1576483252364/OSCB-Bild_1_Tears+and+Tear+FilM_HYALURONIC+ACID+%28HA%29+is+a+Biopolymer+with+very+high+water+binding+capacity_Wasser+BLAU+%2B+3D.png Deeper Insight THERAPY 3 - Tear Supplementation Hyaluronic Acid (blue) is a large bio-polymer with very high water-binding capacity. It typically occurs e.g. in the jelly-like vitreous body of the eye, in the viscous fluid of joints, and in connective tissue. https://oscb-berlin.org/therapy-options-in-dry-eye-disease-1-1-1 daily 0.75 2017-04-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a05c8b3a0411d59c659da0/1486894740501/ Deeper Insight Therapy 2 - RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e387e8ebbd1aeecf441f99/1576483321665/ Deeper Insight Therapy 2 - RISK FACTORS Contact lens wear is a general stress factor for the Ocular Surface and Tear Film. CL e.g. increase the frictional forces during the normal eye movements and blinking. Therefore CL wear has higher requirements for tear volume and (lubricative) quality than required in non-CL-wearers. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a05c8b3a0411d59c659da3/1486899263613/OSCB-GIF_ANIMATION+BLINK+%28FRONTAL%29+%2BCL+Soft+17-8%2C+60-72_.gif Deeper Insight Therapy 2 - RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a05c8b3a0411d59c659da1/1486895523688/ Deeper Insight Therapy 2 - RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a893ebe6f2e14f1954c3d9/1576483321661/OSCB-Bild_6.0_Dry+Eye+Disease_THERAPY_DIETARY+APPROACHES+to+Dry+Eye+Prevention+and+Therapy.png Deeper Insight Therapy 2 - RISK FACTORS Important for sufficient moisture and health of the ocular surface are certain dietary facotrs such as https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a05c8b3a0411d59c659da2/1486896892826/ Deeper Insight Therapy 2 - RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a05c8b3a0411d59c659d9f/1486898310860/ Deeper Insight Therapy 2 - RISK FACTORS https://oscb-berlin.org/overview-therapy-4-antiinflammatory-therapy daily 0.75 2021-08-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a87fb9c534a5fdedb1a52d/1576483425799/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc32303e00be6887d83a88/1576483425787/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc2d1e6a4963d651bbadac/1576483425780/OSCB-Bild_6_Dry+Eye+Disease_REGULATORS+of+INFLAMMATION+-Free+Fatty+Acids-+Arachidonic+Acid+%2BEicosanoids+%2B+NSAID%2B+CORTIKOSTEROIDS.png Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bbec622e69cfbfda64a237/1576483425756/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bd6eb3f7e0ab949c6fa47f/1576483425796/OSCB-Bild_6_Dry+Eye+Disease_REGULATORS+of+INFLAMMATION+-Free+Fatty+Acids+-Arachidonic+Acid+%2BEicosanoids++%2B+AZITHROMYCIN.png Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy Azithromycin has an anti-inflammatory effect via several pathways. It limits the metabolism of inflammatory lipid species upstream of the crucial molecule Arachidonic Acid, which leads to its decreased production, and it also inhibits its downstream metabolisation into all the inflammatory Eicosanoids. Further effects concern e.g. an inhibition of inflammatory cytokine and chemokine production by phagocytes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bbfb361e5b6ce5662b0d3e/1576483425753/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy Many different signaling molecules with a pro-inflammatory effect (= Inflammatory Mediators) are involved in inflammatory processes and modulate Inflammation. All signaling molecules act via binding to a respective receptor of a target cell. Inflammatory Cytokines are produced by many cells types and the same is true for inflammatory lipid mediators (eicosanoides) that encompass well known molecules such as different prostaglandins and leukotrienes - among other functions they induce pain. More restricted are vasoactive amines such as Histamine, Bradikinin and Serotonin that are produces by mast cells (mc in the diagram) and phagocytes (granuclocytes and macrophages - indicated by ´gr´and ´mo´in the diagram). An unstable and therefore short-time and short-distance acting mediator is the gas Nitric Oxide (No, blue-green in the diagram) that is produced mainly by macrophages and endothelial cells of blood vessels that induce relaxation of the peri-vascular smooth muscle cells and thus dilatation of the vessel with subsequent slow blood flow. Together with Histamine this promotes the inflammatory extravasation of plasma and cells into the tissue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a473d91b10e362c2255a7b/1576483425763/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy A Key Event in chronic MUCOSAL INFLAMMATION is the Recruitment of Leukocytes by Cell Adhesion Molecules (CAMs). Leukocytes that carry the Lymphocyte Function-Associated Antigen 1 (LFA-1) bind to vascular endothelial cells and also to cells in the tissue, e.g. epithelial cells, by InterCellular Adhesion Molecule 1 (ICAM-1). ICAM-1 is up-regulated in on the tissue cells in inflammation and makes them vulnerable to lymphocytes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a4675abe6594d9783ec099/1576483425759/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy As an early key event in Inflammation, blood components are recruited to the site in order to support the inflammatory attempt of clearing the tissue from a pathogenic impact. This occurs by influence on the endothelial cells of the vessel walls. Vaso-active amines increase the permeability of the vessel walls leading to outflow of PLASMA, which is mainly water, into the tissue with subsequent formation of EDEMA. Leukocytic protective CELLS from the vessels are also recruited by the help of adhesion molecules, that are expressed on the endothelium: in acute inflammation these are mainly phagocytic cells - in chronic inflammation they are mainly lymphatic cells that promote the progression into immune-mediated inflammation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc5122a5790a1de0cbd9f7/1576483425772/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58b8785c17bffc617e89f23c/1576483425775/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy The source of Glucocorticoids and their precursors is the Adrenal Gland from where they are distributed via the blood stream throughout the body. The Adrenal Gland is seen here in the diagram in the bottom middle over the ´ovary´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc331e6a4963d651bbe71a/1576483425790/OSCB-BILD_6_Dry+Eye+Disease_THERAPY_BLOCKING+of+the+Cell+Adhesion+Molecules+ICAM-1+%26+LFA-1+by+LIFITEGRAST+inhibits+Key+Events+of+Ocular+Inflammation.png Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy The interaction of the Cell Adhesion Molecules ICAM-1 on tissue cells and its partner LFA-1 on leukocytic immune cells is a central regulatory and promoting mechanism in the inflammatory pathways in moderated to severe Dry Eye Disease. The blocking of this interaction by a small blocking molecule (Lifitegrast), that is small enough to be applied topically, thus appears as a promising new therapeutic route to treat ocular surface disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a461ece58c623a227b2936/1576483425747/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc345520099e5b48804af5/1576483425778/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy Glucocorticoids are mighty own hormones of the body for the maintenance of chronic stress. Therefore they are involved in many different processes and they also block almost all steps of inflammation very effectively. Due to their pleiotropic action on many systems the also have many potent side-effects even in topical use at the ocular surface, particularly when given ´too long ... and too much´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a43457d2b857e5fe101dde/1576483425744/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy The central amplifying factor in many vicious circles in Dry Eye Disease is a chronic inflammatory process inside the tissue that is progressively dysregulated and the tissue including that of glands is progressively destructed. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58b1d9ca579fb3b20165232a/1576483425766/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a87f9129687f223ffb1eb2/1576483425793/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy Topical AZITHROMYCIN, a macrolide antibiotic that was originally developed for infectious ocular surface disease, appears to have if fact multiple favorable effects in Meibomian Gland Dysfunction (MGD). According to literature reports, has: (1) an antibiotic effect against the overgrowth of the commensal lid bacteria, (2) it blocks the breakdown of irritant lipids into potent inflammatory free fatty acids, and (3) it has a stimulating effect on the secretory cells (Meibocytes) of the Meibomian Gland. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58b859db86e6c0ff013cfc03/1576483425750/OSCB-Bild_6_Dry+Eye+Disease_INFLAMMATION%2C+Pathophysiology_Pathways+of+Ocular+Surface+INFLAMMATION_SIMPLE_QUER.png Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bdb351f5e2319165a0a01e/1576483425769/OSCB-Bild_6_Dry+Eye+Disease_INFLAMMATION_REGULATORS+of+INFLAMMATION+-+Free+Fatty+Acids+-+Arachidonic+Acid+%26+Eicosanoids.png Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy NSAID (middle left of the diagram) specifically block the cyclo-oxygenases (COX) enzymes that maintain the downstream metabolisation of inflammatory core substance Arachidonic Acid into the multitude of the, mainly but not exclusively, inflammatory Eicosanoids that encompass prostaglandins and leukotrienes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58bc2ed08419c2e3d2c0475d/1576483425784/ Deeper Insight THERAPY 5 - ANTI-INFLAMMATORY Therapy The diagram shows molecules that are important for antigen-presentation and lymphocyte activation and are thus promising targets for anti-inflammatory Presently used, and highly effective, drugs at the ocular surface typically block the synthesis of two important interleukins (soluble signaling molecules abbreviated by IL and a number) for lymphocyte activation (IL-1 and IL-2). Lifitegrast is using another target in the form of blocking the interaction of adhesion molecules. Apart from many other functions in inflammation, these also assist in antigen-presentation by mechanically linking the respective cells - please see below for ´Lifitegrast´. https://oscb-berlin.org/therapy-options-in-dry-eye-disease-1-1-2-1 daily 0.75 2017-08-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a60b65f7e0ab195a247f8a/1576483381357/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58aaec8b17bffc6029d9de1c/1576483381332/OSCB-Bild_6.0_Dry+Eye+Disease_MGD_MGD-PATHOPHYSIOLOGY+Main+CONSEQUENCES%2C+LIDRAND-Schema+-+GETEILT+2%2C+Ophthhalmologe+2009.png Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a58aa6b3db2bd67b5f3c9f/1576483381329/ Deeper Insight THERAPY 4 - MGD-Therapy The main pathogenetic factors for obstructive Meibomian Gland Dysfunction are an inspissation of the lipid secretum due to increase melting point and a hyperkeratinization of the ductal system and lid margin. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a9b8c2a5790a1849ec4e69/1576483381338/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58aa0185d1758e84118341bc/1576483381363/ Deeper Insight THERAPY 4 - MGD-Therapy The most innovative and effective treatment for obstructive Meibomian Gland Dysfunction is presently an automated simultaneous lid warming and gland expression procedure. This is achieved by the LIPIFLOW device that was built according to the ideas of Prof. Donald Korb from Boston, MA, who is a one of the most experienced clinician for Meibomian Gland Dysfunction. (Images: Courtesy of TearScience Inc.) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a9fb921e5b6ce697e1db41/1576483381360/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction+%28MGD%29%2C+PHYSICAL+THERAPY+in+MGD+-+Lid+WARMING+from+INSIDE.png Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a595b9e4fcb5591c3af427/1576483381326/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a5b0483e00be70fab028ef/1576483381341/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction%2C+MGD+THERAPY_EYE+LID+WARMING.png Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a9b383e6f2e14f195d409d/1576483381335/ Deeper Insight THERAPY 4 - MGD-Therapy Increased pressure inside the Meibomian glands leads to a PRESSURE ATROPHY with (1) Dilatation of the ductal system, (2) Destruction and Rarefication of the secretory Meibocytes in the Acini and (3) Destruction of the Acini and integration or acinar remnants into the ductal wall. (An overview of a gland in the left top corner shows the area where the higher magnifications of the main image comes from - histological photomicrographs in H&E stain) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab077f725e25c4fabcd7cb/1576483381347/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a5bb98bebafbe99fd6ac35/1576483381350/ Deeper Insight THERAPY 4 - MGD-Therapy The BLEPHASTEAM Googles for automated application of exactly dosed heat together with moisture is probably the most well known type of MGD Googles Image: Courtesy of THEA Pharma.. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a17eb4d1758ebeb9fde977/1484575482564/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989be54cf81e0e201dc1145/1576483381366/ Deeper Insight THERAPY 4 - MGD-Therapy LID HYGIENE is typically done with some kind of disposable pad similar to those that are used for removing make-up. In addition some kind of liquid is applied from clean water to special lipid solutions - the use of detergents, however would likely disturb the tear film lipid layer. The more vigorous the hygiene becomes, the more it transforms into a lid SCRUB which needs a certain carefulness in order to avoid wounding. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a56a1ef5e2312c09fc0546/1576483381322/ Deeper Insight THERAPY 4 - MGD-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ab1381ebbd1ab59c7d4a9d/1576483381354/ Deeper Insight THERAPY 4 - MGD-Therapy Manual Meibomian Gland EXPRESSION with the own fingers is possible only to a limited extent and mainly for the lower eye lids as shown here. Expression between thumb and index finger is most effective in the middle of the lid, whereas the nasal and temporal regions are less accessible. Only small amounts of inspissated secretum are expressed here from two orifices in about the middle along the lid. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a5b877579fb3f4644552f5/1576483381344/ Deeper Insight THERAPY 4 - MGD-Therapy https://oscb-berlin.org/overview-on-meibomian-gland-dysfunction-mgd-1 daily 0.75 2021-06-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f7e/1486722272490/OSCB-Bild_2_Meibomian+Gland_HIGH+vs.+LOW++Delivery+Conditions+of+the+Meibomian+Gland.png Meibomian Gland Dysfunction (MGD) The Meibomian Glands can have different types of pathology that are differentiated easiest into High vs. Low Delivery Conditions. In both cases this can be either due to the secretion rate of the secretory acini deep in the tissue or due to influences on the amount of delivery out of the gland onto the lid margin, typically by obstruction. Other influences on the secretum can possibly occur inside the ductal system, as e.g. inflammation and bacterial colonization, and may influence the amount of delivery. The most frequent condition is Low Delivery Obstructive MGD by Blocking of the Terminal Duct and Orifice (top in right diagram)whereas the secretion rate of the acini appears to remain normal. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f7d/1505833242307/ Meibomian Gland Dysfunction (MGD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f84/1505833336048/ Meibomian Gland Dysfunction (MGD) Histological Studies of the Ocular Surface Center Berlin (OSCB) have revealed some typical alterations of Meibomian Glands in MGD (right) compared to normal glands (left). This concerns an obstruction of the orifice by keratinized material (top right) and signs of gland atrophy (bottom right). This is explained in more detail for the higher resolution image below. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f86/1505833421233/OSCB-GIF_MGD+MEIBOM-Folien+zur+ANIMATION+etc.+aus+WAKAYAMA_ANIMATION+OBSTRUCTION_Vollformat.+39-1.5fps_OHNE+Text_GUT.gif Meibomian Gland Dysfunction (MGD) The Pathomechanism of Obstructive MGD is schematically shown in this ANIMATION. In the NORMAL state the OIL is first SECRETED in an acinus and then driven towards the orifice by the secretory pressure that results from continuing secretion. In OBSTRUCTION of the terminal duct and orifice, the secreted oil can not get out of the gland to be delivered onto the lid margin - which results in a lack of oil on the tear film. The continuing secretory pressure inside the gland leads to a dilatation of the ductal system and apparently the stasis of oil in the gland pre-disposes the secretum to become inspissated. Eventually the increased pressure enters the secretory acini and destroys the secretory cells (Meibocytes). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f7f/1505833275074/ Meibomian Gland Dysfunction (MGD) In contrast to the schematic morphology of a normal Meibomian gland (right side) an OBSTRUCTED gland in MGD (left side) typically has signs of dilatation of the ducts and an atrophic destruction of the secretory acini due to the increased pressure inside the blocked gland that can not get out its oily secretum. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f83/1505833324633/ Meibomian Gland Dysfunction (MGD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c130f04c0dbf237236050b/1505833213057/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__5.2.4_Lid-Margin_FREE-Lid-MARGIN-vs.-Inner-and-Outer-BORDER.gif Meibomian Gland Dysfunction (MGD) Meibomian Gland Dysfunction (MGD) is sub-summarized under Blepharitis as the main form of posterior blepharitis which concerns the area of the posterior lid border and is typically not overt inflammatory. Anterior blepharitis of the outer lid border and eye lid skin, in contrast, is typically overt clinical inflammatory. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f7c/1505833235462/ Meibomian Gland Dysfunction (MGD) The initial type of MGD is asymptomatic - since it goes without symptoms. It is also clinically inconspicuous and is termed as Non-Obvious MGD (NOMGD). A high proportion of elderly individuals conceivably has NOMGD which may already lead to an unnoticed destruction of the Meibomian glands inside the eye lids due to the increased pressure inside obstructed glands. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c131afcd39c3ab6e4be751/1622545386529/OSCB-Bild_2_Meibomian+Gland_AUSSCHNITT+Histology+of+Obstructive+Meibomian+Gland+Dysfunction+%28MGD%29+Ophthalmologe+2009_2.png Meibomian Gland Dysfunction (MGD) The obstruction in MGD results, due to continuing secretion, in an increased pressure inside the gland. This leads to dilatation of the ductal system with the long central duct (cd) and the connecting ductules (de) to the acini. The epithelium appears distinctly thinned in places compared to the normal about four cell layers Increased pressure also affects the secretory cells (a). The susceptible secretory cells disappear (asterisk) and the acini transform from solidly filled cell clusters into hollow sacs (encircled) with a loss of secretory capacity. Eventually, destroyed acini with residual secretory cells can be integrated into the wall of the central duct as seen here indicated by double arrowheads on the left side of the duct. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f82/1505833318711/ Meibomian Gland Dysfunction (MGD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f7a/1486544282558/OSCB-GIF_MEIBOMDR%C3%9CSE%2C+Normal+%2B+Obstruktion+%28Ophthalmologe+2009%29_AUFRECHT+_20-72_2-1fps_.gif Meibomian Gland Dysfunction (MGD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f80/1505833285635/ Meibomian Gland Dysfunction (MGD) The terminal duct of the Meibomian glands is an ingrowth of the cornified surface epithelium. The wall of the Meibomian orifice (open arrow) therefore consists of fully cornified epidermis with luminal anuclear keratin squames. The shed epitheliallamellae are typically located inside the lumen of the orifice and can easily obstruct it when additional factors occur, such as Meibomian Lipids with increased melting point. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a844b0b3db2bfa5de46f81/1505833302294/ Meibomian Gland Dysfunction (MGD) https://oscb-berlin.org/new-page-5 daily 0.75 2019-06-14 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58a8801203596ede2f083e15/1487437857759/ DEEPER INSIGHT into ... MGD THERAPY https://oscb-berlin.org/diagnosis daily 0.75 2019-06-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d696323e00bed5027cc64e/1530788381275/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d566c3197aea2fd6f470f9/1530787994200/LINK-BILDCHEN_3+DIFFERENT+VITAL+STAINS.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d554dd2e69cf144b839f7e/1530737534011/LINK-BILDCHEN_INCOMPLETE+BLINKS%2C+TearScience+LIPIVIEW_2.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e2383b3a0411db1e39265e/1491220564197/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Some+DIAGNOSTIC+TECHNIQUES+for+Dry+Eye+Disease.png Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d54a0515d5db43927931e3/1530737057222/LINK-BILDCHEN_DIAGNOSTIC+EXPRESSION.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e4b91fd2b857cb9a5522e0/1530735475381/LINK-BILDCHEN+Tr%C3%A4nen+MENISCUS+Neu+4.JPG Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d524f2be659456292ad2ea/1490363640421/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a9b52acd39c3b276e0426b/1530958078235/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye_DIAGNOSIS-LINK-Bildchen.gif Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d51e3937c5818457056ced/1530787870044/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d3edb28419c2d3806dce48/1490283969495/ Overview DIAGNOSIS Topographers provide a wide array of Tests and Investigations for the Ocular Surface and Tear Film and can thus not only assist in the Diagnosis of Dry Eye Disease but also in e.g. contact lens fitting by measuring the ocular surface Topography. The Oculus Topographer 5M is available with an advanced software package termed as´Dry Eye Report´from Jenvis, Jena Germany. This allows to fill in the complete Dry Eye Data Set including the questionnaire and ´digests´ the data into a graphic visualized report representation that allows even the novice in the field to perform a thorough and understandable Dry Eye Diagnosis. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58c6f78446c3c46572335556/1490727465784/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Estimation+of+TEAR+VOLUME%2C+Meniscus+HEIGHT%2C+Meniscus+CURVATURE+%282x+aus+Ophthalmologe%29_.png Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d54a66e58c628ea813b034/1530788323853/LINK-BILDCHEN_LIPID+INTERFEROMETRIE.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e22bf8ff7c50123186fe97/1491217415708/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_TEAR+FILM+LIPID+LAYER+%28TFLL%29+THICKNESS+Interferometry_BLINK+ANALYSIS%2C+TestScience+LIPIVIEW.png Overview DIAGNOSIS Analysis of the BLINK PATTERN is an important feature of Ocular Surface and Tear Film investigation- but this is typically not supported by available devices. Blinking is of utmost importance for the correct formation of the pre-ocular tear Film and its lipid layer (TFLL) because even a sufficient amount and delivery of lipids from the Meibomian Gland does still not render an intact and stable tear film when the blink pattern is disturbed and e.g. partial blinks occur. Partial blinks are difficult to record manually in particular when the patient is aware of this. Much easier and more reliable is an automatic recording of the blink pattern together with investigations suh as lipid layer thickness, as seen here with the Lipiview, or of Non-Invasive Break-Up Time (NI-BUT). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d51c0186e6c04becf9c783/1530787827994/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d52114414fb51d9a4a7adc/1491244559315/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d51b47be65943dee02e040/1530787413853/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d51f2be3df28a024aab4dc/1530787914362/LINK-BILDCHEN_NI-BUT_VITAL+Staining.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d8e5e4d482e99539180c9f/1530788062851/LIPCOF-CONJUNCTIVAL-FOLDS Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d69f5b9f7456928cc48dcf/1530788431765/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d69f102994ca9ba729c6fc/1530788351274/LINK-BILDCHEN_TearLab+Abnahme.GIF Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d6974de3df283d54bdd19c/1530447877246/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dcb0ea414fb5e91acf1e8e/1530736028853/LINK-BILDCHEN_QUESTIONNAIRE+GANZ.GIF.png Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e4be5fd2b857cb9a554726/1491385973942/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_The+TEAR+MENISCUS+is+an+Indicator+for+Pre-Ocular+Tear+VOLUME_5.png Overview DIAGNOSIS The pre-ocular Tears are lined at the upper and lower Lid Margins by a fluid rim that contains more tears and is termed the TEAR MENISCUS. It sits on the posterior lid border and its bottom is the Line of Marx, that, in turn, represents the surface of the muco-cutaneous junction (MCJ) - a specialized epithelial transition zone that transforms the aqueous-wettable mucosa of the conjunctiva into the oily-dry skin. In cross-section (left image), the tear meniscus has a roughly triangular shape where the back side is constituted by the cornea, or the conjunctiva, and the frontal anterior side forms a parabolic curve. The filling and thus volume of the tear meniscus corresponds to the volume of the pre-ocular tears. Analysis of the meniscus thus provides surrogate parameters for the tear volume. With increasing tear volume the apparent height, i.e. the apparent upper end of the tear meniscus, increases and the curvature, i.e. the radius of the circle that best approximates the parabolic anterior surface of the tear meniscus, becomes larger (please see the diagram). With decreasing tear volume the opposite changes occur. Decreased tear volume typically causes increased mechanical friction. When the decreasing tear meniscus is due to increased evaporation, which is the most frequent case this also leads to tear hyper-osmolarity (The relative thickness of the tear film and of its lipid layer are exaggerated in the drawing, relative to the tissue of the lid margin). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58cf947520099e8bad8162fc/1491384831672/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+%28auf+gelbem+ZETTEL%29_NEU+2.png Overview DIAGNOSIS The process of DIAGNOSIS becomes easier to understand when we remember the basic course of pathophysiology in DRY EYE DISEASE because this indicates events that can be analyzed. BASIC CAUSATIVE FACTORS, i.e. a deficiency of tear secretion and/or a deficiency of tear film formation, lead to the PRIMARY PATHOLOGIES of Tear FIlm Deficiency of different type and/or Ocular Surface Tissue Damage of any kind (which both certainly influence each other). Both of the Primary Pathologies area governed by Sequences of SECONDARY PATHOGENETIC FACTORS. All explained factors and events may represent potential targets for Diagnosis. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58d692e76b8f5bf825353866/1530736172860/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58cc4da4d482e9f3c6a665fa/1489784237079/ Overview DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e234fdbe65941eab1a415e/1530787948647/LINK-BILDCHEN_Lid+Wiper+Epitheliopathy+%28LWE%29.JPG Overview DIAGNOSIS https://oscb-berlin.org/impressum daily 0.75 2019-07-11 https://oscb-berlin.org/diagnosis-2 daily 0.75 2018-07-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de6106db29d689a04d019f/1490968859920/ Deeper Insight Diagnosis-2 SECRETION The aqueous lacrimal SECRETION volume is measured by SCHIRMER´s Test that collects the tears on a strip of filter paper, hanged over the lower temporal lid margin, during a period of 5 minutes . The ocular surface and the lacrimal glands are connected by a neural reflex arc for secretory regulation. It consists of the afferent sensory (blue interrupted line) and the efferent secreto-motor green solid line) nerves - together with the regulating brain stem including the efferent superior salivary nucleus (SSN dark green). There are different variations of the original test that either add a topical anesthesia or, instead, add a nasal mucosal stimulation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de638e725e25e520d25263/1490969506423/ Deeper Insight Diagnosis-2 SECRETION When topical anethesia is used this blocks all stimulation that may be exerted by the toughing the bulbar surface of eye lids and transforms the Schirmer test into a test for BASAL Sectetion. This is termed SCHIRMER 1 Test with anesthesia. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de3457ebbd1a51648e7588/1490957409173/ Deeper Insight Diagnosis-2 SECRETION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de6a4d1e5b6ce8febd2cfb/1490971225014/ Deeper Insight Diagnosis-2 SECRETION DIAGNOSTIC EXPRESSION Test. At a normal appearing lid margin (top images) it is not immediately clear whether the Meibomian Glands are functional or not. Functional means whether clear liquid oil can be delivered through an open orifice onto the lid margin with the mild pressure that occurs during a blink, since these holocrine glands are anyway continuously secreting lipids. The testing for patency of the gland orifices is thus the aim of the DIAGNOSTIC EXPRESSION Test. When mild pressure is applied onto the lid margin from the skin side - simply with a finger (middle image) or with a special standardized instrument (Meibomian Gland Evaluator, MGE, TearSeience Inc - lower two images) a normal gland will ´deliver´ clear oil as a little puddle onto the lid margin around the orifice (middle figure). An obstructed gland (MGD) in contrast will not deliver any lipids upon mild diagnostic expression. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de64d759cc68e9b094e252/1490969836526/ Deeper Insight Diagnosis-2 SECRETION SCHIRMER 2: The SCHIRMER 1 Test with nasal stimulation is a modification of the simple Schirmer 1 test (without anesthesia) in which the nasal mucosa is stimulated by a cotton swab during the full time (5min) of the test. This test is useful when the ordinary Schirmer 1 test has revealed a borderline low score. It is performed in order to test the maximal stimulated capacity of aqueous secretion. The results of this test show the best correlation with ocular surface damage as seen upon Rose Bengal staining. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58de629b1b631b8ad50f5f18/1490969263645/ Deeper Insight Diagnosis-2 SECRETION The original simple Schirmer test (termed SCHIRMER 1) collects the tears that are secreted during 5 minutes without anesthesia. https://oscb-berlin.org/diagnosis-3 daily 0.75 2018-07-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0ff1dbf629afc261c8dbf/1492965802162/ Deeper Insight Diagnosis-3 TEAR FILM This schematic diagram from a 2005 article by members of the OSCB in ´The Ocular Surface´ explains the main steps in the pathogenesis of the CHRONIC MUCOSAL INFLAMMATION of the Ocular Surface in Dry Eye Disease. Due to an alteration of the Ocular Surface Epithelium this will produce inflammatory mediators in order to mount a protective tissue reaction that is intended to get rid of the pathogenic stimulus. From here, a sequence of secondary events is initiated that encompass (1) an elevation of antigen-presentation molecules and (2) of cell adhesion molecules that induce the influx of cells from the vascular compartment into the tissue and paves there destructive way through the tissue, as well as (3) the activation of connective tissue degrading Enzymes (Matrix-Metalloproteinases, mainly MMP9) in the assumed best interest to provide space for the inflammatory protective cells. All of this would be no major problem ... IF the alteration was only acute and not chronically continuing - which is however unluckily the typical case in Dry Eye. Therefore the typical development here is that the intended protective reaction may transform into a chronic mucosal inflammation that is immune-modulated by the lymphatic cells that are a normal protective component of the tissue. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfee5086e6c029f7c0cfc0/1492968420101/ Deeper Insight Diagnosis-3 TEAR FILM When the Tear Film BREAK-UP Time (BUT) is estimated conventionally, the vital stain FLUORESCEIN is used to make the tear film visible in order to see its Break-Up - this is termed Fluorescent BUT (F-BUT). A Break-Up typically occurs in a small area and quickly becomes larger. In the region of the Break-Up the epithelial cells are exposed to the ambient air and are prone to dry out. The exposure of the epithelium is immediately sensed by the sensory nerves and initiates an eye blink to remove the old ruptured tear film and to spread a new one. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfd0f71b10e31ed4509af7/1491064222425/ Deeper Insight Diagnosis-3 TEAR FILM The superficial layer of the tear film is composed of lipids with possibly some minor amounts of associated proteins. The lipid film is very thin but is still conceptually separated into a much thicker outer layer of non-polar lipids that appear to represent the ´lid on the pot of warm tears´ that retards aqueous evaporation. Underneath is a much thinner sub-layer of non-polar lipids, possibly with minor contents of proteins, that can connect the above layer to the underlying aqueous phase. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfec82d482e9ebf96eb542/1492957196901/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Tear+Film+LIPID+LAYER+Analysis+and+Corneal+Topography%2C+TEARSCOPE+Advanced%2C+HOCHKANT_k%C3%BCrzer.png Deeper Insight Diagnosis-3 TEAR FILM The Analysis of the Tear Film LIPID LAYER (TFLL) by INTERFEROMETRY is already available since the 1980s by a simple to use handheld device - the TearScope, that was invented by the Tear Film Specialist Jean-Pierre GUILLON. Apart from estimating the thickness of the Lipid Layer it is also possible to obtain the Non-Invasive Tear Film BREAK-UP Time (NI-BUT). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfd22ccd0f6881b7718b1b/1491064255228/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_TEAR+FILM+LIPID+LAYER+%28TFLL%29+THICKNESS+is+measured+by+INTERFEROMETRY+%28Interference+Colors%29.png Deeper Insight Diagnosis-3 TEAR FILM The schematic representation of a normal tear film lipid layer in INTERFEROMETRY shows a whirly pattern of reddish-golden interference colors. The interference is typically best seen when the room light is dimmed. A real normal interference image is shown a few images below. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfd685d482e9ebf96dc7d3/1491064585383/ Deeper Insight Diagnosis-3 TEAR FILM Another feature of a TFLL in interferometry is that the lipid layer tends to fold in a plicated fashion in the down-stroke of a blink ... and unfolds again in much the same shape during the up-stroke. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fb5cbb579fb35db9de1975/1544785201970/ Deeper Insight Diagnosis-3 TEAR FILM In the Pathogenesis of Dry Eye Disease, HYPER-OSMOLARITY (inset to the right) is an important SECONDARY PATHOGENETIC FACTOR, that is induced by the PRIMARY PATHOLOGY of a LIPID DEFICIENCY in the tear film with increased evaporation of the aqueous phase of the tears. These Pathologies are based on the BASIC CAUSATIVE FACTOR of a GLAND-DYSREGULATION - in this case: in Meibomian Gland Dysfunktion (MGD). Pathologies of the aqueous secretion, on the other hand, which are not considered here, are induced by a Dysreguation of the aqeuous Lacrimal Gland. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfe9ab03596ea584881934/1492956782032/ Deeper Insight Diagnosis-3 TEAR FILM A very exact ANALYSIS of the Tear Film LIPID LAYER is possible by the LipiVIEW and the LipiSCAN devices (from TearScience Inc.). The interferenceimage is optained over a wide area and is automatically analysed. Over a time of approximately 30 seconds various parameters are measured such as the minimal, maximal and median Thickness of the Lipid Layer and in addition the Blinks are recorded in order to see partial blinks. The devices can also analyse the morphology of the Meibobmian glands by non-contact MEOBIGRAPHY. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d7825016e1f19b19e6dd/1491130271674/ Deeper Insight Diagnosis-3 TEAR FILM Ocular Surface conditions with a deficiency ("lack") of tear film lipids have a a deficient Tear Film Lipid Layer (TFLL) and result in a loss of the water evaporation retarding effect. The water of the aqueous tears evaporates then (blue undulated arrows) rapidly but leaves the solved salts and functional proteins (both shown here as white particles) in the remaining tear fluid. The consequence is that (1) the tear volume decreases which causes a lower tear meniscus height (please see there) and decreased lubrication. In addition (2) in the remaining tear fluid the dissolved salts and hydrophilic proteins are more concentrated (relatively more particles per volume) so that the tears are ´hyper-osmolar´. These tears exert a ´hyper-osmolar´water-dragging stress onto the underlying epithelial cells, which represents an inflammatory stimulus and may contribute to the onset of cell damage and potentially to Dry Eye Disease when the condition becomes chronic. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfef22e6f2e17ea4b6caeb/1491070778561/ Deeper Insight Diagnosis-3 TEAR FILM TOPOGRAPHERS are Multi-Purpose devices that are stand-alone, are typically equipped with different illumination systems for different purposes and are connected to a computer with an appropriate software system for evaluation and storage of examination results. Certainly very useful for Dry Eye Diagnostics is the possibility to perform Non -Invasive Tear Film Break-Up (NI-BUT) measurements that allow the measurement of Tear Film stability without interfering with it by addition of marker any substances. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e10020d1758e214423eab4/1494799537303/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png Deeper Insight Diagnosis-3 TEAR FILM The schematic diagram depicts the pathophysiology in Dry Eye Disease - as it is explained in the new HOLISTIC DYNAMIC CONCEPT on DRY EYE DISEASE. - BASIC CAUSATIVE FACTORS that impair the formation of a stable tear film - either by a Gland Dysregulation that leads to a deficiency of tear components and/or by an impairment of blinking that leads to an inability to form a stable FILM from the available tears - cause the PRIMARY PATHOLOGY of Tear Film Deficiency. This will then, via secondary factors such as the discussed hyper-osmolarity, eventually induce a SURFACE DAMAGE of the Ocular Surface tissue, first of the epithelium, that can proceed to a chronic mucosal inflammation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e100b5ebbd1a7ec6413327/1494799524335/ Deeper Insight Diagnosis-3 TEAR FILM Tear Film OSMOLARITY is an important parameter and an important secundary pathogenetic factor in Dry Eye Disease. The respective measurement can nowadays be done very easily with a hand-held instrument (TearLab) that uses sterile disposable Tips for uptake of tears and can measure the osmolarity very precisely. By this device it is possible to determine a detrimental tear osmolarity simply and directly in the practice besides the patient in a few seconds and to have the degree of hyperosmolarity measured very exactly. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dfcff91b10e31ed4509180/1491064235862/ Deeper Insight Diagnosis-3 TEAR FILM The view of pro-ocular Tear FILM as a basically three layered liquid film is the leading concept for roughly the last 70 years since Eugene WOLFFS original description in 1946 ... and this concept still appears to hold true. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fb5c8ab8a79b0b91ba2227/1544785201967/HYPEROSMOLARITY+induces+SURFACE+DAMAGE+and+INFLAMMATION.png Deeper Insight Diagnosis-3 TEAR FILM INCREASED OSMOLARITY (Hyper-Osmolarity) draws that water out of the epithelial cells of the ocular surface by osmotic forces. The osmotic stress represents a danger signal for them and induces, via gene regulation, the production of inflammatory cytokines that mount an inflammatory reaction. This type of reaction is the basic protective strategy of most cells ... but can have unwanted side-effects when it becomes chronic. https://oscb-berlin.org/diagnosis-4 daily 0.75 2020-11-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7c577414fb5b577b2b179/1544701053354/Zones+of+highest+FRICTION+at+the+Ocular+Surface.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Friction occurs mainly at the bulbar surface inside the palpebral fissure and at the palpebral posterior lid border, mainly in the upper eye lid but also to a certain extent in the lower lid. The elevated epithelial lip of the lit wiper at the posterior border wipes for a distance of about 10mm back and force over the bulbar surface during each of the frequent blinks. The frictional force that occurs is here concentrated on a relatively small surface whereas the same friction on the other (bulbar) side is distributed over a much larger are. Normally the friction is sufficiently limited by a sufficient tear volume and by a rich mucin-water gel that is enriched on the Lid Wiper Surface by many goblet cells and goblet cell crypts (indicated in the 2 images on the right side). In conditions of increased friction, such as in Dry Rye Disease and in Contact lens wear a pathologically too high mechanical friction and thus alteration and wounding of the epithelium will first occur at the lid wiper. This is indeed true because it was observed by KORB and colleagues that Lid Wiper Epitheliopathy (LWE) is the first area if vital staining in elevated friction conditions. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e79bd0ebbd1a4ffd7ea674/1544701053335/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+-+MAIN+CAUSATIVE+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7ae6f86e6c0ca598c879d/1544701053339/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e24bbe9f7456e98872cfc7/1544701053337/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Increased Mechanical FRICTION is a main pathogenetic factor for Ocular Surface Disease. Friction occurs during all movements of the eye ball relative to bony orbita and the lids, particularly during blinking. Pathologically increased friction occurs when the normal lubrication by the tear film is reduced due to the pathology in e.g. Dry Eye Disease or due to external factors such as a contact lens. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d39b2e69cfd46abdf1e1/1605523392624/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e1527103596ea584937fc0/1544701053402/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Topographer Systems are typically more advanced. They usually provide more advanced illumination annd visualization techniques and a better image quality together with measurements and a structured documentation that can make the clinical daily life more effective and enjoyable. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7ad7cbf629ae56bebf781/1544701053332/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dff9a2bf629afc26150baa/1544701053352/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE VITAL STAINING of Epithelial Alterations of the Ocular Surface is typically evaluated in a semi-quantitative fashion by estimating the amount of staining, which is basically equivalent to single stained cells, by comparison with a chart that shown certain model grades. A popular Grading System is the OXFORD SCORE because this is easy to use and produces relatively reliable results. The staining intensity shown here schematically represents a medium (grade 2) staining on the Oxford Scale. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dff71df5e2318397ea95aa/1544701053350/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE The severity of ocular surface staining that occurs due to pathological epithelial alterations is typically determined according to the amount of stained cells. The location also appears to have some significance because nasal staining (top image) is typically mild and unspecific, whereas temporal staining (bottom image), i.e. in a location where the fresh tears pour out of the excretory lacrimal ducts into the conjunctival sac, typically indicates a more severe condition and is somewhat specific for Dry Eye Disease (Schematic drawings according to observations of UCHIYAMA and colleagues 2009). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d3dc03596ea5848f6a03/1605458725865/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Lid-Parallel Conjunctival Folds (LIPCOF) occur when the structural collagen meshwork of the conjunctival connective tissue (Lamina propria) is degraded by proteinases, mainly Matrix-Metalloproteinase 9 (MMP9). The loosening of the conjunctiva is termed ´conjunctivochalasis´. MMP9 is increasingly activated during the chronic inflammatory process in Dry Eye Disease. The loose conjunctiva is then ´shoveled up´ by the relatively sharp posterior lid border and folds up onto the posterior lid border. For simplicity, a zone with ´NORMAL´ collagen structure is shown here directly besides the ´CONJUNCTIVOCHALASIS´. It must however be assumed that the whole conjunctiva is relatively homogeneously affected by this destruction in Chronic Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d01abebafbe50cb922a8/1544701053370/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE A schematic drawing of an eye with several Lid Parallel Folds (LIPCOF, indicated by arrows) superimposed over the posterior lid border inside the tear meniscus (blue arrows). (The lid margins are slightly everted to show the free lid margin with the tear meniscus) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0b81fa5790ad96799f28e/1544701053368/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE ROSE BENGAL Vital Staining of the Lid Wiper Epithelium of the marginal Conjunctiva. The staining is intensely reddish-pink. Vital staining of the Lid Wiper is pathological and termed Lid Wiper Epitheliopathy (LWE), whereas the staining for the thin line (arrows) at the outer aspect is normal and indicates the physiologically stainable Line of MARX. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7bb36be659415d09cb23f/1544701053344/Zones+of+highest+FRICTION+at+the+Ocular+Surface.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Friction occurs mainly at the bulbar surface inside the palpebral fissure and at the palpebral posterior lid border, mainly in the upper eye lid but also to a certain extent in the lower lid. Under normal conditions there is enough lubrication available by a sufficient amount of tear fluid and additional lubricative proteins such as lubricin. In conditions of increased friction, such as in Dry Eye Disease and Contact lens wear the normal movements of eye ball and lids against each other already cause epithelial damage. This can be made visible by ´Vital Staining´using different stains because the wounded cells pick up the stain and the normal ones don´t. The staining at the eye ball is termed as corneal or conjunctival staining or superficial punctate keratitis or just as ´Vital staining´. The vital staining of the elevated epithelial lip of the lid wiper zone at the posterior lid border is termed Lid Wiper Epitheliopathy (LWE) by KORB and colleagues. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7a960579fb37611b394ac/1544701053409/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Advance illumination techniques allow imaging of the Meibomian glands in unprecedented clarity. Thereby the exact structure of normal Meibomian Glands and precise information on the their alteration in gland drop-out can be obtained. Images: Courtesy of TearScience Inc. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e26d8de58c62c8b2a4b2f6/1544701053360/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e151bde4fcb5ff91c07014/1544701053399/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e7a685f5e231613be1e9bb/1544701053406/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dff65b17bffc2b387c313c/1544701053348/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE A schematic drawing at the cellular level indicates the image of fluorescein stained epithelial alterations that occur as small dots. The stained dots that originate from single stained cells in principle, are shown here a polyhedral objects. Often pathogenetic impacts on the epithelium, due to e.g. friction or hyper-osmolarity. will affect more than one individual cell in a place, so that the stained spots may become larger than one cell diameter. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e14d9b03596ea584934521/1544701053388/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE A convenient test for determining the level of the protein-destroying enzyme Matrix-Metalloproteinase 9 (MMP9) became available. It indicates by an immune-assay based color reaction whether the MMP9 level is over the normal range. The MMP9 test can thus indicate the presence of a chronic tissue destroying inflammatory process that would require therapeutic intervention, even when clinical signs of tissue destruction have not yet occurred. The MMP9 test may thus offer a new preventive approach in Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e150f0f7e0ab3ba8783f61/1544701053394/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58dff3535016e1f19b130159/1544701053346/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE A schematic drawing indicates the image of fluorescein stained epithelial alterations that occur as small dots. The size of the stained dots, that originate from single stained cells in principle, is somewhat too large here in the drawing in order to make them better visible. Specific patterns of staining can occur such as here band-like within the palpebral fissure. Staining patterns may each allow proposals on the mechanism of pathogenetic alteration. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e26171bebafbe50cc73e51/1544701053356/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0b74c725e250f9723c4d2/1544701053363/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+-+FLUORESCEIN+stains+Cornea+better+than+Conjunctiva.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE FLUORESCEIN Vital Staining of the Lid Wiper Epithelium of the marginal Conjunctiva. The staining is intensely bluish-green. Fluorescein stains the pathological Lid Wiper Epitheliopathy (LWE) but it is also lying on the tarsal conjunctiva in the middle of the image and partly demarcates substructures such as crypts and other surface irregularities. This superimposition of fluorescein on the epithelium is not a real staining because, as seen in the next image with Lissamine Green staining, the tarsal conjunctiva in such patients is typically unaltered and healthy. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d0dad1758e214422f152/1544701053372/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Frictional forces on the bulbar conjunctiva occur basically during every movement of the eye ball within its nice and cozy mucosal tissue shell behind the eye lids, e.g. during every position of gaze and by fixation of moving objects. Of particular importance is the movement of the eye lids over the eye ball during the blink, because this occurs most frequently, covers a long contact area and also exerts the mechanical force of the lid tension onto the eye ball (please see the animation below). This applies mainly to the upper lid that travels more than one hundred meters a day over the eye ball but also the lower lid exerts some movements along the eye ball. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e2657b197aea8ba608b03e/1544701053358/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0d4d91b10e31ed458dcad/1544701053380/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e372991e5b6c8ff92a1ae8/1544701053342/HYPEROSMOLARITY+induces+SURFACE+DAMAGE+and+INFLAMMATION.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE The schematic drawing illustrates the impact of a local spot of hyper-osmolarity that may occur e.g. due to a local break-up of the tear film with local evaporation of water and accumulation of the remaining tear salts and proteins (gray spots). The hyper-osmolarity drags water from the epithelial cells with potential shrinkage and cell disruption. This represents a danger signal and activates an inflammatory response with production of inflammatory mediators. In chronic conditions and with wide-spread hyper-osmolarity a pro-inflammatory milieu may build up that can lead to the onset or promotion of Dry Eye Disease. (for schematic reasons the local hyper-osmolarity zone here is much too small because it may be assumed that even a small local hyper-osmolarity will affect several or many cells at a time). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e14cbfcd0f6881b77d9806/1544701053386/OSCB-Bild_6_Dry+Eye+Disease_PATHOPHYSIOLOGY_LIPCOF+Folds+in+CONJUNCTIVOCHALASIS+are+based+on+a+MMP9+Proteases+in+Chronic+Inflammation_.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Lid-Parallel Conjunctival Folds (LIPCOF) occur when the structural collagen meshwork of the conjunctival connective tissue (Lamina propria) is degraded by proteinases, mainly Matrix-Metalloproteinase 9 (MMP9). The loosening of the conjunctiva is termed ´conjunctivochalasis´. MMP9 is increasingly activated during the chronic inflammatory process in Dry Eye Disease. The loose conjunctiva is then ´shoveled up´ by the relatively sharp posterior lid border and folds up onto the posterior lid border. For simplicity, a zone with ´NORMAL´ collagen structure is shown here directly besides the ´CONJUNCTIVOCHALASIS´. It must however be assumed that the whole conjunctiva is relatively homogeneously affected by this destruction in Chronic Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e1513c20099e5b01e5fc84/1544701053397/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e0b7d920099e5b01e174a8/1544701053365/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+-+LISSAMINE+GREEN+stains+the+Conjunctiva+very+well.png Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE LISSAMINE GREEN Vital Staining of the Lid Wiper Epithelium of the marginal Conjunctiva. The staining is intensely dark-green and stains the conjunctiva very well and intense. Here it makes the pathological Lid Wiper Epitheliopathy (LWE) visible since the conjunctival cells, that are altered in conditions of increased friction such as Dry Eye Disease and Contact Lens Wear, pick up the stain whereas the other normal conjunctival cells on the tarsal conjunctiva in the middle of the image do not stain. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e219bde6f2e17ea4c921af/1544701053382/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE Figure-Legend: The basic structure of the CONJUNCTIVA is composed of a loose, but still sufficiently solid, meshwork of collagen fibers. In the clefts between the fibers stromal cells and cells of the innate and specific immune system lead their daily life together with bypassing support structures such as blood vessels (left middle), lymph vessels and nerve fibers (faint yellow lines). MMP9 cleaves the long collagen fibers into fragments and thus destroys the structural basis of the tissue in the praiseworthy attempt to provide more space for the protective ´inflammatory cells´. Problems only occur when the inflammation becomes chronic and thus undermines all attempts for a final ordered repair of the tissue ... which results in a constant conjunctival destruction and thus tissue loosening termed conjunctivochalasis https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58e1508244024364dba66362/1544701053390/ Deeper Insight Diagnosis-4 SURFACE TISSUE DAMAGE https://oscb-berlin.org/d-blick-auf-die-augenoberflaeche daily 0.75 2020-11-25 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfc1ebec81db800017142fc/1560026825018/OSCB-Berlin.org%2C+%28c%29+ENK_CORNEA%2C+HORNHAUT+-+Hornhaut-Rad+LIMBUS_20_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b89653e00beb869ae9b01/1500219787796/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8f40f017db2a6ddc8b106/1560027036884/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA%2C-HORNHAUT-%28Spot0965%29---%C3%9CBERBLICK-Zusammenstellung_WEB-30_.gif D-BLICK auf ... die AUGENOBERFLÄCHE Der Aufbau der Hornhaut hat für ihre Transparenz ein sehr dicht gepacktes, wasserarmes, zentrales Bindegewebe (Stroma), das auf beiden Seiten von einem Epithel gegen Wassereintritt ´abgedichtet´ wird. Das äussere, oben liegende Epithel liegt zum Tränenfilm, das innere Epithel (Endothel) zum Kammerwasser der vorderen Augenkammer. Das Endothel enthält ausserdem noch Wasserpumpen, die das Stroma ständig aktiv entquellen. (Die hier im mikroskopischen Bild sichtbaren Lücken des Stroma sind künstlich entstanden bei der Präparation und somit nicht ´echt´) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a8003a8419c278e3fa7352/1504182343104/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfbf41e5036250001292ecd/1560015911452/GIF_BILDER_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-MARKIERTE-STRUKTUREN-%2B-AUF-LABNOTES_DEUTSCH_28-72%2C-9-3sec-PSE_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499db/1491764053408/ D-BLICK auf ... die AUGENOBERFLÄCHE Durch den Lidschlag wird eine sehr dünne und gleichmäßige Schicht von Tränenflüssigkeit - TRÄNENFILM - erzeugt, der die Augenoberfläche auch in der geöffneten Lidspalte feucht erhält. Leider bleibt der Tränenfilm immer nur eine begrenzte Zeit stabil, danach bricht auf und verschwindet wie eine Seifenblase. Dies ist das Signal für einen neuen Lidschlag um einen neuen Tränenfilm auszubreiten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963ddb7ff7c50a4828ae255/1499717073164/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfc0c4068782500014b9fd2/1560022095024/OSCB-Berlin.org_Die-HORNHAUT-ist-das-KLARE-FENSTER-des-Auges-f%C3%BCr-den-Eintritt-von-Licht-zum-Sehen.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5996e41e59cc68c3682c8883/1503061034102/GIF_Animation_Augenoberfl%C3%A4che-NERVENSYSTEM-Schmerz_600pix-19-2_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5959264a36e5d3644bbbd317/1499014741333/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59708259db29d60f27b08e10/1500545635366/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8fcb9268b96a337fadbe4/1505295558446/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA--%28Spot0965%29%2C--Epithel-%2B-BOWMAN-SCHICHT.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d88e72b263fbc3a5c72106b/1569253177794/OSCB-Berlin.org%2C+%28c%29+ENK_CORNEA%2C+HORNHAUT+-+Geordneter+Aufbau+der+Kollagenfibrillen+in+Schichten+mit+KERATOZYTEN_NEU_.png D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59d272cf197aea63f7f8c598/1506964180909/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Grundlagen-der-Anatomie---Zell--%26-Gewebelehre.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963bc756b49984858d9ef26/1499714906015/ D-BLICK auf ... die AUGENOBERFLÄCHE Hornhautrand/ LIMBUS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfc179dbea42d0001d2ba79/1602585110491/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA%2C-HORNHAUT-%28Spot0965%29---%C3%9CBERBLICK--Histo-%2B-Zeichnung-AOF__.jpg D-BLICK auf ... die AUGENOBERFLÄCHE Der Aufbau der Hornhaut/ Kornea in verschiedenen Schichten wird in mikroskopischen Schnittbildern mit zunehmender Vergrösserung erkennbar. Die zentrale Dicke der Kornea beträgt 0,5 Millimeter. Die Kornea ist ein gebogenes, klares Scheibchen von Bindegewebe (Stroma), das auf beiden Seiten von einem Epithel bedeckt ist. Nach aussen zum Tränenfilm liegt das dickere Epithel (mehrschichtiges Plattenepithel) und nach innen zum Kammerwasser der vorderen Augenkammer liegt das einschichtige flach-kubische Endothel. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b903b8b1ffb69891e6cf1b/1597744493213/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KONJUNKTIA_BECHERZELLEN-der-Konjunktiva-mit-freigesetztem-MUZIN.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b4e79ff7c5001fe69d29e/1500205355366/GIF_Animation-BULBUS-Schichten%3B-HORNHAUT-%2B-SKLERA-%2B-BINDEHAUT-%28PSE-7-3%29_2.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595a592ee3df282571dff88a/1499093373216/ D-BLICK auf ... die AUGENOBERFLÄCHE Neben dem Schutz vor Infektionen ist die Reduzierung von Reibung bei allen Augenbewegungen und beim Lidschlag eine sehr wichtige Funktion für die Augenoberfläche. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595a55fd725e25902aeef027/1499092490327/ D-BLICK auf ... die AUGENOBERFLÄCHE Die Bindehaut/ Konjunktiva trägt durch die Bildung von Abwehrstoffen, vor allem Immunglobulin A (IgA) zu ihrer eigenen Immunabwehr bei. Die Schemazeichung in der Mitte zeigt, dass IgA von Plasmazellen (P) im Bindegewebe der Lamina propria gebildet wird und dann mit Hilfe eines Transportermoleküls (´Sekretorische Componente´ SC, hier rot) im Epithel an die Oberfläche transportiert wird. Im Bild rechts wird dies mit entsprechenden immunhistochemischen Färbungsmethoden an der Konjunktiva nachgewiesen - hier sind die sind IgA und die Plasmazellen grün markiert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8ff8ef9a61ebc232a4b2f/1505296278945/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA--%28Spot0965%29%2C-Stroma%2C-DESCEMET-Membran%2C-Endothel.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59666de129687fde551edc6a/1499885036448/ D-BLICK auf ... die AUGENOBERFLÄCHE Bei einem grösseren Defekt der Stammzellen für das Epithel der Hornhaut (hier grün) kann die Epithelschicht der Bindehaut (hier rosa) mit ihren eingelagerten Schleimzellen (Becherzellen, rote Punkte) die Hornhaut überwachsen. Dies wird als ´KONJUNKTIVALISIERUNG´ der Hornhaut bezeichnet und kann, je nach Lage der Überwachsung, zu einer starken Sehverschlechterung führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3bac8de0cc631d15d8ea6f/1597746331943/OSCB-Berlin.org_FEINSTRUKTUR+der+AUGENOBERFL%C3%84CHE+und+TR%C3%84NENFILM_20_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59513e5cd1758eec9b6a18d3/1560014836200/ D-BLICK auf ... die AUGENOBERFLÄCHE Die FUNKTIONSEINHEIT der Augenoberfläche ist hier schematisch gezeigt in der Aufsicht (Foto) . Sie besteht aus der `EIGENTLICHEN´ sichtbaren Augenoberfläche von Hornhaut/ Kornea und Bindehaut/ Konjunktiva sowie aus den unter der Haut liegenden Schleimhaut-´ANHANGSORGANEN´ (Mukosale ´ADNEXE´). Zusammen bilden sie die Gesamte Augenoberfläche. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963bbe272af651ef936c944/1569253755431/ D-BLICK auf ... die AUGENOBERFLÄCHE Bitte wählen Sie das Organ Ihres Interesses ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8f5974c326d96e36316f3/1505293725187/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA--%28Spot0965%29%2C-Stroma-und-Endothel-mit-Wasser-Pumpen.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3b9042c1f83c774dead44b/1597744454728/OSCB-Berlin.org_Bindehaut--KONJUNKTIVA-u-Hornhaut--KORNEA-liegen-im-Konjunktival-SACK-gegen%C3%BCber%2C-mit-Kessing-Space_2_20_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b52bcb8a79b10f85825d7/1500205761784/Zeichnung-AUGENOBERFL%C3%84CHE-%2B-Zeichnung-BULBUS-...-zus.-PPT-3D-MONTIERT_DEUTSCH-auf-Labnotes_WEB_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ede756d1758e5b5949798b/1491986297340/OSCB-BILD_Augenoberfl%C3%A4che_EIN+NEUER+BLICK+auf+die+AUGENOBERFL%C3%84CHE++...BASIC+FUNCTIONAL+COMPLEX+%28%C3%9Cberblick+Funktionelle+Komplexe%29.png D-BLICK auf ... die AUGENOBERFLÄCHE Eine stark vereinfachte Schemazeichnung stellt die beiden wesentlichen Funktionskomplexe dar: (1) die Tränen-PRODUKTION durch 3 verschiedene Drüsenarten, die Wasser, Lipid (Öl) und Schleim (Muzin) produzieren und (2) die FORMATION eines Tränen-FILMs durch den LIDSCHLAG https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a3e989893fc0da8f01a988/1503914391471/OSCB-Berlin.org_Der-NORMALE-AUGENINNEN-DRUCK-h%C3%A4lt-die-runde-Form-des-Augapfels-BULBUS-aufrecht_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfbe5a84342210001dc6848/1560012208113/OSCB-Berlin.org%2C+%28c%29+ENK_CORNEA%2C+HORNHAUT+-+VEREINFACHTE+%C3%9Cbersicht+zum+Aufbau+der+Hornhaut_20_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfc01a5328dd3000159ed5d/1597737972048/OSCB-Berlin.org_Die-Augen-Bindehaut-Konjunktiva-hat-eine-empfindliche-Oberfl%C3%A4chenstruktur%2C-Epithel-mit-Becherzellen%2C-Mikrovilli-und-Glykokalyx-%28Koloriertes-LM-%2B-TEM_E%2BN.KNOP--c-ENK_10+LINK+BILDCHEN.gif D-BLICK auf ... die AUGENOBERFLÄCHE - Feinstruktur der Zell Oberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfbff75ef43040001f0ed3b/1597737843586/OSCB-Berlin.org_Hornhaut-RAND-LIMBUS_10+LINK-Bildchen_WEB.gif D-BLICK auf ... die AUGENOBERFLÄCHE - Hornhaut-Rand / Limbus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfbfeddffebc20001245efe/1597737597279/OSCB-Berlin.org_Die-Bindehaut-KONJUNKTIVA---eine-wichtige-Unterst%C3%BCtzung-der-Hornhaut_10+LINK+BILDCHEN_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE - Bindehaut / Konjunktiva https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfbfc1d2cd25f0001b2a4b8/1597737581108/OSCB-Berlin.org_Die-HORNHAUT-ist-das-KLARE-FENSTER-des-Auges-f%C3%BCr-den-Eintritt-von-Licht-zum-Sehen_10+LINK+BILDCHEN_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE - Hornhaut https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfbfc0598f3530001a018ba/1597737557574/GIF_Animation-BULBUS-Schichten%3B-HORNHAUT-%2B-SKLERA-%2B-BINDEHAUT-%28PSE-7-3%29_2_10+LINK+BILDCHEN_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE - Aug-Apfel/ Bulbus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cfbf6ceef43040001f09ecc/5cfbf6cf52439d0001d43f98/1560019939406/GIF_BILDER_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-MARKIERTE-STRUKTUREN-%2B-AUF-LABNOTES_DEUTSCH_400-7-3_.gif D-BLICK auf ... die AUGENOBERFLÄCHE - Augenoberfläche und Tränen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b8f87f1f318da34569bdac/1505294473871/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomie-und-Histologie-der-Humanen-KORNEA%2C-HORNHAUT-%28Spot0965%29---EPITHEL%2C-Basalmembran%2C-BOWMAN-Schicht--Histo-%2B-Zeichnung-AOF_WEB-30_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccd5d9099e55f00013f6939/1556962718627/Augenoberfl%C3%A4che+mit+CORNEA+von+SOA+HOMEPAGE_Repariert+%28Pfeil+raus%29+%2B+HG+recht+HELLER+%2BKORNEA+BLAU+%2B+Rd.+GR%C3%9CN+%2B+LICHTSTRAHLEN+%2B+OSCB.png D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599ea80b03596ec874cbb8be/1503569950766/OSCB-Berlin.org_Die-ORGANE-der-AUGENOBERFL%C3%84CHE--sind-verbunden-und-arbeiten-zusammen_NEU-7-2017_2.gif D-BLICK auf ... die AUGENOBERFLÄCHE Die ORGANE DER AUGENOBERFLÄCHE sind anatomisch KONTINUIERLICH und wirken zusammen: Die ´unsichtbaren´ Schleimhaut-Anhangsorgane liegen unter der Haut versteckt. Sie bilden mit der TRÄNENDRÜSE den Hauptteil der (wässrigen) Tränenflüssigkeit - während die Ableitenden Tränenwege die Tränen nach dem Baden der ´eigentlichen´ sichtbaren Augenoberfläche wieder von der Vorderfläche des Auges entfernen und in Nase ableiten. Die Abbildung links zeigt einen der Ausführungsgänge der seitlich/ temporal oberhalb des Augapfels liegenden Tränendrüse im lichtmikroskopischen Bild - gezeigt ist die Region, wo der Ausführungsgang in den Bindehautsack einmündet. Die Abbildungen rechts zeigen einen von je zwei Tränenpünktchen pro Auge, die nasal/ innen auf dem unteren und oberen Lidrand liegen, etwa dort wo die Wimpernreihe endete. Die Tränenpünktchen bilden den Beginn der Ableitenden Tränenwege - gezeigt ist ein Tränenpünktchen im rasterelektronenmikroskopischen Bild und das anschliessende Tränenkanälchen im lichtmikroskopischen Bild. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f8c7d135688f32ed11d0e8f/1603042595779/OSCB-Berlin.org%2C+%28c%29+ENK%2C+Erich+%26+Nadja+Knop_ANIMATION+ANATOMIE+UND+FNKTION+DES+AUGES_NEU-6_30-12-2%2C5_.gif D-BLICK auf ... die AUGENOBERFLÄCHE Die Augenoberfläche ist, wenn man dem Licht folgt, der erste Teil des Sehorgans und daher von größter Bedeutung für alles was danach und weiter ´hinten´ mit dem Licht, mit den entsprechenden Nervensignalen und dem Seheindruck passiert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5959430b3e00bea5c50266f6/1499022103902/ D-BLICK auf ... die AUGENOBERFLÄCHE Die Bindehaut/ Konjunktiva hat den typischen Aufbau einer Schleimhaut. Dies ist schematisch gezeigt (Bild rechts) und in einer mikroskopischen Abbildung (links). Auf einer Unterlage aus lockerem Bindegewebe mit Kollagenfaserbündeln liegt eine ebenfalls relativ lockere aber doch abdichtende Epithelschicht. Im Epithel befinden sich neben den üblichen Zellen auch Schleimzellen (Becherzellen, die Schleimstoffe sind hier rot angefärbt, Abb. links oben). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596f8a0337c58152ae4bb5b4/1500482061637/ D-BLICK auf ... die AUGENOBERFLÄCHE Der normale Augeninnendruck von etwa 15 mmHg (Millimeter Quecksilbersäule) ist notwendig um die normale runde Form des Auges aufrecht zu erhalten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59665230ebbd1a7eb725badb/1499877944076/ D-BLICK auf ... die AUGENOBERFLÄCHE Blick in den KONJUNKTIVAL-SACK: Die Augenoberfläche besteht aus der klaren Hornhaut in der Mitte und der darum herum liegenden Bindehaut. Die Abbildung zeigt einen licht-mikroskopischen Gewebeschnitt von einer Region, wie sie in der Schema-Zeichnung links mit einem Rechteck markiert ist. Die Bindehaut/ KONJUNKTIVA des Lides (links) und die Hornhaut/ KORNEA des Augapfels (rechts) liegen sich im Konjunktival-Sack direkt gegenüber. Beide haben an der Oberfläche eine dichte Zellschicht (Epithel), auf der der Tränenfilm liegt (fehlt in diesem mikroskopischen Präparat). Wenn die Lider geöffnet sind, dann ist die Epithel-Zellschicht der Hornhaut von Austrocknung bedroht und die Zellen sind das erste Gewebe der Augenoberfläche, das Schaden nimmt bei einem Trockenen Auge. Die sehr unterschiedliche Struktur von Bindehaut und Hornhaut ist leicht erkennbar. Die Konjunktiva ist locker und unregelmässig aufgebaut. Die Kornea, die für Durchlässigkeit des Lichtes optimiert ist, hat einen sehr regelmässigen und straffen Aufbau mit dichtem Epithel und dicht gepackten Bindegewebsfasern in der Schicht darunter (Stroma). Die verbleibenden winzigen Unregelmässigkeiten an der Oberfläche der Kornea werden vom Tränenfilm aufgefüllt, so dass die Oberfläche dann perfekt glatt ist für eine perfekte Lichtbrechung und eine perfekte Sehschärfe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963bfdb46c3c47ad1933724/1499714938865/CONJUNCTIVA-LINK-Bildchen.gif D-BLICK auf ... die AUGENOBERFLÄCHE Bindehaut/ KONJUNKTIVA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499d4/1560014800509/ D-BLICK auf ... die AUGENOBERFLÄCHE Frühes Konzept über die FUNKTIONELLE EINHEIT der Augenoberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598834e3e3df285a35d6d395/1502098895918/ D-BLICK auf ... die AUGENOBERFLÄCHE Ein BLICK IN DEN TRÄNENFILM. Der mittlere Hauptteil des Tränenfilms vor der transparenten Hornhaut/ Kornea besteht aus wässriger Flüssigkeit. Unten sind die zahlreichen fingerartigen Fortsätze der oberflächlichen Epithelzellen sichtbar. Sie binden mit ihrer Beschichtung aus wasser-bindenden Zuckermolekülen (Glykokalyx) das Wasser an die Zell-Oberläche des Auges und ermöglichen so die Benetzung. Im Tränenfilm wird das Wasser durch die langen Zuckerketten (hier rötlich) löslicher Schleimstoffe (Muzine) gebunden, die im Tränenfilm treiben und das Wasser in ein dünnflüssiges Wasser-Muzin-Gel verwandeln. Oben wird der Tränenfilm von der sehr dünnen Öl-Schicht aus den Fetten der Meibomdrüsen abgedeckt, die eine zu schnelle Verdunstung des Tränenwassers verhindert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595a7215ebbd1a26712db40b/1499099677551/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594ec607e58c624757889801/1498334791554/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963d1c337c581a1a518d56d/1499714892620/ D-BLICK auf ... die AUGENOBERFLÄCHE Hornhaut/ KORNEA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499dc/1491764063417/ D-BLICK auf ... die AUGENOBERFLÄCHE Die Erkrankung des TROCKENEN Auges ist eine prototypische Erkrankung der Augenoberfläche, durch Funktionsstörungen, die letztlich die grundlegenden Funktionskomplexe zur Erhaltung von Feuchtigkeit beeinträchtigen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b4e3b15d5dbaaaf4367ef/1500204613796/OSCB-Bild_3.1.8_Ocular-Surface_VERSCHIEDENE-SYSTEME-REGULIEREN-die-Augenoberfl%C3%A4che_WEB_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499da/1491764044987/OSCB-GIF_Ocular+Surface+Functional+UNIT+%2C%2C%2C+TEAR+FLOW+ALONG+OS+%28aus+GIF+Functional+Unit%29_2-2fps+GIF_.gif D-BLICK auf ... die AUGENOBERFLÄCHE Der TRÄNENFLUSS erfolgt entlang der Organe, die die Funktionseinheit der Augenoberfläche bilden - von der äusserlich unsichtbaren Tränendrüse über ihre Ausführungsgänge auf die Kornea und Konjunktiva und dann durch die Ableitenden Tränenwege, die im Lidwinkel unter der Haut versteckt sind, in die Nase. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3ba7efe0cc631d15d88076/1597745149003/OSCB-Berlin.org_EPITHEL+VERGLEICH+Bindehaut-KONJUNKTIVA+und+Hornhaut-KORNEA%2C+umgekehrt_20_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594cc9db2cba5e2de129817a/1498204651636/ D-BLICK auf ... die AUGENOBERFLÄCHE Die intakte Funktion der Augenoberfläche beruht auf der Steuerung durch REGULATORISCHE SYSTEME, vor allem das Nervensystem, das endokrine Hormonsystem und das Immunsystem. Sie steuern Wachstum und Reifung der Organe, wie auch ihre konkrete funktionelle Regulation in Abhängigkeit von inneren und äusseren Reizen. Dies betrifft z.B. das Sekretionsvolumen, oder die Frequenz und Vollständigkeit des Lidschlages und viele andere Funktionen, die dafür sorgen, dass sich sowohl die Augenoberfläche wohl fühlt ... wie auch ihr ´Besitzer´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a3ee7b6a4963c599012729/1503915655428/OSCB-Berlin.org_Durchtritt-der-Sehnervenfasern-durch-den-Sehnervenkopf_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b900fc32601e9f3a780a92/1597744463327/OSCB-Berlin.org_Die-Augen-Bindehaut-Konjunktiva-hat-eine-empfindliche-Oberfl%C3%A4chenstruktur%2C-Epithel-mit-Becherzellen%2C-Mikrovilli-und-Glykokalyx-%28Koloriertes-LM-%2B-TEM_E%2BN.KNOP--c-ENK.gif D-BLICK auf ... die AUGENOBERFLÄCHE Die Oberfläche einer Zelle der Augenbindehaut (Konjunktiva) an der Grenze zum Tränenfilm zeigt in sehr starker elektronenmikroskopischer Vergrösserung zarte Fingerartige Fortsätze (Mikrovilli, MV) und Falten (Mikroplicae, MP). Fest in der Zellmembran verankert ist ein dichter Saum vom relativ langen faserigen Molekülen, wie auch im Querschnitt durch Mikrovilli zu erkennen ist (oben rechts). Diese bestehen aus Zuckerartigen Substanzen und werden daher auch insgesamt als Glykokalyx (Zuckermantel) bezeichnet. Die Glykokalyxmoleküle haben eine starke Bindungsfähigkeit für Wasser und sind darum eine wichtige Voraussetzung dafür, dass die Augenoberfläche das Wasser der Tränenflüssigkeit binden kann und damit ´benetzbar´ ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595256763a04110e4f61658d/1498571580503/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE+%2818cm-72%29_25-5fps_NUR+QUER.gif D-BLICK auf ... die AUGENOBERFLÄCHE Für den TRÄNENFLUSS auf der Augenoberfläche spielt der Lidschlag der Augenlider über die Oberfläche des Augapfels eine wichtige Rolle, da er die neu produzierten Tränen zum dünnen TränenFILM verteilt. Ausserdem trägt er auch dazu bei, die ´gebrauchten´ Tränen über die Ableitenden Tränenwege in die Nase zu entsorgen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595a4d7e03596e73b40bbbcf/1499090317134/ D-BLICK auf ... die AUGENOBERFLÄCHE Ein wichtiger Schutz der Augenoberfläche vor den Eindringen fremder Substanzen und auch der Infektion durch Mikroben (Bakterien und Viren) besteht in dem Maschenwerk der wasserbindenden Scheimstoffe (Muzine). In dieser Barriere befinden sich auch spezielle Abwehrstoffe, die in der Konjunktiva produziert werden und die als Anti-mikrobielle Peptide und Proteine bezeichnet werden. Hierzu zählt auch Immunglobulin A. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499d5/1486910677761/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b3dfc1e5b6c3094c7d0bb/1500200454657/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cfc0bf4bc7b3a00013fa63c/1560022017339/GIF_BILDER_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-MARKIERTE-STRUKTUREN-%2B-AUF-LABNOTES_DEUTSCH_400-7-3_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/595cbec646c3c48b867c2f44/1597744473468/ D-BLICK auf ... die AUGENOBERFLÄCHE Die schematische Zeichnung zeigt die Zelloberfläche und die untere Schicht des Tränenfilms mit Beschriftung. Wasserbindende Zuckerartige Moleküle, die auch als Schleimstoffe (Muzine) bezeichnet werden, befinden sich als Glykokalyx in der Zellmembran verankert und als lösliche Muzine (aus Becherzellen der Bindehaut - siehe nächste Abbildung) im Tränenfilm darüber. In mikroskopischen Präparaten kann man Muzine mit einer rosa-farbenen Farbreaktion (PAS) anfärben. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59592d601e5b6cee37466a91/1499016564080/ D-BLICK auf ... die AUGENOBERFLÄCHE Hornhaut/ Kornea und Bindehaut/ Konjunktiva von der Seite betrachtet. Zentral auf der Hornhaut sitzt eine kleine formstabile/ harte Kontaktlinse. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499d3/1491763984557/ D-BLICK auf ... die AUGENOBERFLÄCHE In einer ANIMATION ... ein Mini-Film ... wird hier eine (sehr) schnelle Übersicht über die wichtigsten Komponenten der Augenoberfläche gezeigt, die zusammen ein komplexes Netzwerk bilden um so die Gesunderhaltung des Gewebes und die ersten Schritte des SEHENS sicher zu stellen. - Wiederholtes Anschauen der Animation hilft beim Verständnis ... und in langsameren Versionen könnte es langweilig werden ;-). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a3ebaab8a79b579245b794/1503914937448/GIF-ANIMATION_Der-Beitrag-der-Augenoberfl%C3%A4che-zu-ANATOMIE-%2B-Funktion-des-AUGES_Fertig_.gif D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5963cc69db29d68787e80e16/1499714128363/ D-BLICK auf ... die AUGENOBERFLÄCHE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598cafd6a5790abbb451b7f9/1502392304337/ D-BLICK auf ... die AUGENOBERFLÄCHE Ein BLICK IN DEN TRÄNENFILM zeigt die besprochenen Strukturen im funktionellen Zusammenspiel. Der mittlere Hauptteil des Tränenfilms vor der transparenten Hornhaut/ Kornea besteht aus wässriger Flüssigkeit. Unten sind die zahlreichen fingerartigen Fortsätze der oberflächlichen Epithelzellen sichtbar. Sie binden mit den wasser-bindenden Zuckermolekülen der Glykokalyx das Wasser an die Zell-Oberfläche des Auges und ermöglichen so die Benetzung. Im Tränenfilm treiben die langen Zuckerketten (hier rötlich) der löslichen Muzine aus den Becherzellen, die das Wasser in ein dünnflüssiges Wasser-Muzin-Gel verwandeln. Oben wird der Tränenfilm von der sehr dünnen Öl-Schicht aus den Fetten der Meibomdrüsen abgedeckt, die eine zu schnelle Verdunstung des Tränenwassers verhindert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea36589f74563722d499d2/1484129516823/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_f%C3%BCr+BANNER%2C+STREIFEN+AUGENOBERFL%C3%84CHE+ATW+%2BUSM_.jpg D-BLICK auf ... die AUGENOBERFLÄCHE https://oscb-berlin.org/d-traenen-und-traenenfilm daily 0.75 2020-11-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c70f7be65943202e87e8c/1503424772110/OSCB-Berlin.org_Perfekte-Gl%C3%A4tte-des-Tr%C3%A4nenfilms-ist-notwendig-f%C3%BCr-perfekte-Sehsch%C3%A4rfe.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596bb8a5db29d6afc4b92919/1500231852900/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596b8a4f914e6bd0dee43647/1500219995861/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-3D-%C3%96L-RUND_.gif D-BLICK auf ... Tränen und Tränenfilm Die Transparenz der Hornhaut/ Kornea ist eine Vorbedingung für das Sehen aber sie ist noch nicht ausreichend für die Sehschärfe. Erst durch einen sehr dünnen und gleichmäßigen Tränenfilm wird die korrekte Lichtbrechung und eine perfekte Sehschärfe ermöglicht. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594e5639f5e231db4262e69f/1503934039414/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596bb91ecd0f68fd357f619c/1500231985216/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a430eea803bb05775beccf/1597737272780/OSCB-Berlin.org_DR%C3%9CSEN-der-Augenoberfl%C3%A4che_3_WEB_LINK-Bildchen-2-auf-ZETTEL.gif D-BLICK auf ... Tränen und Tränenfilm DRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a42b8b197aead11e28c354/1597737243478/Augenoberfl%C3%A4che%2C-TR%C3%84NEN%2C-Tr%C3%A4nendr%C3%BCse_SCHEMA_LINK-Bildchen.gif D-BLICK auf ... Tränen und Tränenfilm TRÄNEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a419b36f4ca3e5e091687b/1597737290345/GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_600pix-10-2_.gif D-BLICK auf ... Tränen und Tränenfilm LIDSCHLAG - FILM-Formation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3b883c2904263de4648926/1597737033343/OSCB-Berlin.org_FEINSTRUKTUR+der+AUGENOBERFL%C3%84CHE+und+TR%C3%84NENFILM_20_.jpg D-BLICK auf ... Tränen und Tränenfilm Nach aktuellen Messungen könnte die DICKE DER TRÄNENFILM-SCHICHT noch etwas dünner sein, als in dieser Schemazeichnung, die ihn etwa so dick zeigt, wie die Zellhöhe von Epithelzellen der Bindehaut/ Konjunktiva. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594e53b778d171adad023c43/1498305494388/ D-BLICK auf ... Tränen und Tränenfilm TRÄNEN bewirken die FEUCHTIGKEIT der Augenoberfläche, die eine Vorbedingung ist für ihre Gesundheit und Intaktheit - und daher auch für die TRANSPARENZ der Hornhaut/ Kornea. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5958ddd21b631b2ebdfcee89/1498996192396/ D-BLICK auf ... Tränen und Tränenfilm Die ÖL-SCHICHT oben auf dem wässrigen Tränenfilm is äussert dünn - etwa 100 Nannometer und hat damit nur 1-2% der Gesamtdicke des Tränenfilms. Trotzdem besteht sie aus 2 verschiedenen Anteilen. Die äussere Schicht ist wesentlich dicker und hat vermutlich die Funktion wie ein ´Deckel auf einem Topf´ mit warmen Wasser die Verdunstung der wässrigen Tränen zu reduzieren. Da sich aber übliche Fette nicht mit dem darunter liegenden Wasser verbinden können gibt es hierzu eine weitere dünne Schicht von speziellen Fetten und möglicherweise noch anderen Substanzen, die eine Verbindung sowohl mit Fetten wie auch mit Wasser herstellen können. Damit sind sie in der Lage eine gewisse Bindung der äusseren Hauptschicht an den wässrigen Tränenfilm zu erzielen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca9dc6ff4e1fc950f1c4ed4/1597737320860/OSCB-Berlin.org_INHOMOGENIT%C3%84T-des-Tr%C3%A4nenFILMs-st%C3%B6rt-die-Sehsch%C3%A4rfe.gif D-BLICK auf ... Tränen und Tränenfilm Verschwommen Sehen - Instabiler Visus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5958f266f7e0ab5022c9c0e3/1499001453231/ D-BLICK auf ... Tränen und Tränenfilm Schleimstoffe (Muzine) binden das Wasser der Tränen und halten es damit an der Augenoberfläche. Einige Muzine sind direkt in der Zellmembran der Zellen Augenoberfläche verankert. Andere werden von kleinen einzelligen Drüsen (Becherzellen) in der Augenbindehaut direkt in die Tränenflüssigkeit hinein abgegeben. So können sie zusammen mit dem Tränenwasser ein Gel bilden , das eine höhere Stabilität hat als reines Wasser und damit beiträgt den Tränenfilm stabil zu hallten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a44554f14aa1b979bf22a7/1597737361805/OSCB-Berlin.org_Tr%C3%A4nenfilm-LIPIDschicht%2C-Interferometrie_LINK-Bildchen.gif D-BLICK auf ... Tränen und Tränenfilm TränenFILM ÖL-Schicht https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea3cdf893fc0148fb12535/1491928086415/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c736f6a49631b8015b870/1597737100221/Tr%C3%A4nenfilm-AQUARIUM-Animation_Einzel-BILDER_Einzel-BILDER-AUF-ZETTEL-IN-PSE-montiert_CROP_800-8-1_.gif D-BLICK auf ... Tränen und Tränenfilm Ein BLICK IN DEN TRÄNENFILM. Der mittlere Hauptteil des Tränenfilms vor der transparenten Hornhaut/ Kornea besteht aus wässriger Flüssigkeit. Unten sind die zahlreichen fingerartigen Fortsätze der oberflächlichen Epithelzellen sichtbar. Sie binden mit ihrer Beschichtung aus wasser-bindenden Zuckermolekülen (Glykokalyx) das Wasser an die Zell-Oberläche des Auges und ermöglichen so die Benetzung. Im Tränenfilm wird das Wasser durch die langen Zuckerketten (hier rötlich) löslicher Schleimstoffe (Muzine) gebunden, die im Tränenfilm treiben und das Wasser in ein dünnflüssiges Wasser-Muzin-Gel verwandeln. Oben wird der Tränenfilm von der sehr dünnen Öl-Schicht aus den Fetten der Meibomdrüsen abgedeckt, die eine zu schnelle Verdunstung des Tränenwassers verhindert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a452bff5e231b1656ec42f/1597737306182/OSCB-Berlin.org_TR%C3%84NENFILM-%28%26-Augenoberfl%C3%A4che%29_WEB_.gif D-BLICK auf ... Tränen und Tränenfilm TränenFILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c69b2be65943202e7f37d/1503422974878/OSCB-GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2820cm-72dpi%29_33-10fps+GIF.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a452f29f8dceca80db9844/1503941373162/OSCB-Berlin.org_TR%C3%84NENFILM-%28%26-Augenoberfl%C3%A4che%29_WEB_.gif D-BLICK auf ... Tränen und Tränenfilm Die untere Schicht des TRÄNENFILM besteht überwiegend aus Schleimstoffen (Muzine) während sie sich nach aussen zunehmend mit dem Tränenwasser zu einem Muzin-Wasser-Gel vermischen, das den Hauptteil des Tränenfilms bildet. Die ässsere sehr dünne und glatte Abschlussschicht besteht aus einem Ölfilm die die Verdunstung des Wassers vermindert und durch die Gleichmässigkeit der Oberfläche die Lichtbrechung verbessert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c4e793e00be15490c64fa/1503415961950/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a43d9fd55b41551e288e99/1503935917223/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a44adccf81e0d033bd2c89/1503939314230/OSCG-GIF_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_TFLL+LIPID+LAYER+INTERFEROMETRY+%2BDUNKEL+%2B+BREAK+UP+36-12fps+GIF.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596cb34d6f4ca3a637ce7db5/1500296019712/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59568b631b10e37b9e55d115/1498844030013/ D-BLICK auf ... Tränen und Tränenfilm Der Tränen-FILM (links) hat eine hoch geordnete Struktur, die meist als 3-Schichtig beschrieben wird - im Gegensatz zu den Tränen, die typischerweise in Tropfen vorliegen und in ihrer Gesamtheit die Tränenflüssigkeit bilden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c7024d2b85756f3ec0ba7/1503424552959/OSCB-Berlin.org_INHOMOGENIT%C3%84T-des-Tr%C3%A4nenFILMs-st%C3%B6rt-die-Sehsch%C3%A4rfe.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596c780b03596e837b698b80/1503415148099/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596c78381b631b078d963386/1500280895554/ D-BLICK auf ... Tränen und Tränenfilm RISIKOFAKTOREN in der Umwelt - vorwiegend externe austrocknende Umgebungsatmosphäre, Kontaktlinsen und bestimmte konzentrierte Sehaufgaben mit seltenem Lidschlag - haben einen negativen Einfluss auf die Tränenflüssigkeit auf der Augenoberfläche. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c6c89e4fcb51c0ff5f35e/1503423647496/ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_mit-ZETTEL-%2B-OSCB-%2B-TITEL-DEUTSCH_ZUGESCHNITTEN-NUR-CORNEA.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a42c7d3e00be0c32fdb8e9/1597746752462/OSCB-Berlin.org_Die-MUZIN-SCHICHT-des-TR%C3%84NEN-FILMS-verbindet-das-Wasser-mit-der-Augenoberfl%C3%A4che.gif D-BLICK auf ... Tränen und Tränenfilm TränenFILM Schleimstoffe / MUZINE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/594e5fdc6a49632bef923448/1498308584164/ D-BLICK auf ... Tränen und Tränenfilm - WENN diese REGULATIONSSYSTEME GESTÖRT SIND dann kann es zu Funktionsstörungen kommen, die die grundlegenden Funktionskomplexe für die Feuchterhaltung der Augenoberfläche schädigen ... und daher zu der prototypischen Erkrankung führen, die immer dann eintreten kann, wenn die Befeuchtung gestört ist ... das TROCKENE AUGE. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596bb9b915d5dbaaaf4708e7/1500232150473/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596bbdaae6f2e1d4b2f82245/1500233136413/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a43e0dcd39c377e51d608a/1503936032288/GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_600pix-10-2_.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596ca5bf725e25db3a89645e/1597737082698/ D-BLICK auf ... Tränen und Tränenfilm Die verschiedenen Drüsen der Augenoberfläche und ihre Lage sind in dieser schematischen Zeichnung dargestellt. Das Oberlid ist leicht abgehoben vom Augapfel und daher sind die einzelligen Schleimdrüsen der Becherzellen sind in der Fläche der Lid-Bindehaut sichtbar. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c4d738419c244b7374105/1503415677449/OSCB-Berlin.org_Nur-eine-FEUCHTE-Hornhaut-ist-TRANSPARENT_WEB_.gif D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5958cf7fb6ac5073ff426055/1498992519819/ D-BLICK auf ... Tränen und Tränenfilm Über die DICKE des Tränenfilms gibt es unterschiedliche Messungen - nach neueren Vorstellungen liegt sie ungefähr im Bereich der Dicke einer Zellschicht, also ungefähr im Bereich von einem Hunderstel Millimeter (10 Mikrometer). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a45b4c37c581d378e03b53/1503943526674/GIF+FUNCTIONAL+UNIT+%2B+TR%C3%84NEN+REGULATION_aus+GIF+Funct.+Unit+u.+f%C3%BCr_OSCB+HOMEPAGE+ENK___8_Bild7+DEUTSCH_28cm-72.jpg D-BLICK auf ... Tränen und Tränenfilm Der TRÄNENFLUSS an der Augenoberfläche wird in einer animierten Schemazeichnung gezeigt. Das überwiegende Volumen der Tränen kommt aus der Tränendrüse und wird durch mehrere Ausführungsgänge in den Konjunktivalsack abgeben. Die Tränenflüssigkeit ´baded´ die eigentliche sichtbare Augenoberfläche (Hornhaut und Bindehaut) und wird dann durch die Ableitenden Tränenwege in die Nase hinein ´entsorgt´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a41921cd0f681b1cb8edd2/1503926591660/OSCB-Berlin.org_Die+MEIBOMDR%C3%9CSEN+in+den+Augenlidern+produzieren+LIPIDE+f%C3%BCr+den+Tr%C3%A4nenFILM.png D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea3cdf893fc0148fb1253b/1491928589994/ D-BLICK auf ... Tränen und Tränenfilm Einzelne Tränentropfen (hier von verstärktem Tränenfluss, z.B. beim Weinen) stellt Feuchhtigkeit zur Verfügung ... aber der LIDSCHLAG ist notwendig, um diese Tränenflüssigkeit umzuwandeln in einen TränenFILM mit einer bestimmten Schichtung für eine perfekte Sehschärfe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596c89646b8f5bacd67e7d02/1500285293480/ D-BLICK auf ... Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea3cdf893fc0148fb12534/1486911164921/WasserTROPFEN+auf+Blatt+wie+Tr%C3%A4nen%2C+OPT+BREITER+_Fr%C3%BChjhar+2016_.jpg D-BLICK auf ... Tränen und Tränenfilm https://oscb-berlin.org/d-blick-auf-kontaktlinsen daily 0.75 2021-03-24 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd51d2d0d929772ef3a1f04/1557470535085/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+BLOCK+Corneal+SUPPLY_Kontaktlinsen+BLOCKIEREN+HORNHAUT+VERSORGUNG_20_.jpg D-BLICK auf ... KONTAKTLINSEN Kontaktlinsen hemmen die Versorgung und Entsorgung der Hornhaut mit wichtigen Substanzen. Wie das lichtmikroskopische Bild (Mitte) der Hornhaut zeigt, ist sie ein kompliziert aufgebautes Gewebe, das nur solange durchsichtig bleibt wie es nicht beschädigt wird. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd012abec212dcb44ff927c/1557247911683/OSCB-Berlin.org_SKLERALE-KONTAKTLINSE-auf-dem-Auge%2C-Foto-von-der-Seite-%28FOTO-von-keratoconusinfo.wordpress.com%29.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cbc3720ad75390001cd6b51/1557247911704/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen+TAGEStragelinsen%2C+Wegwerf+Kontaktlinsen%2C+Disposable+Contact+Lenses_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd08cd7b208fc568c913bfe/1557247911666/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+EXTENDED+WEAR_Kontaktlinsen+Tagestragezeit%2C+Extended+Wear_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/605b8d95001c534b1a22651d/1616612774751/Animation+sklarale+Linse+%2B+Lidschlag.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1d1c99adc5100013dbc2e/1557254612314/OSCB-GIF_ANIMATION+BLINK+%28FRONTAL%29+%2BCL+RGP+17-8%2C+60-72_.gif D-BLICK auf ... KONTAKTLINSEN kleine formstabile (´harte´) Kontaktlinse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccdf3570092d30001d626d9/1557247911696/OSCB-Berliin.org_INFEKT%C3%96SE-KOMPLIKATIONEN-beim-KONTAKTLINSEN-TRAGEN-%28Fotos%3B-FLORENCE-MALET%29.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1cb85eef1a124826a9dd0/1557253021678/27-TAGES-KONTAKTLINSEN-im-KONJUNKTIVALSACK%2C+RETAINED+DISPOSABLE_2017-BMJ-Publishing-Group%2C-www.bmj.com-content-358-bmj_OPT-WEB.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccde343e4966b5894b18abd/1557247911686/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen+ANPASSUNG_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd0032f99e55f00014f6d94/1557247911672/OSCB%2BText_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_UP+Doppelt+%2B+KONTAKTLINSE+RGP+klein+MOBILER+%2880cm-72dpi%29%2C18-10fps.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccfff0d2585e60001e88025/1557247911656/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccd849b05748e00018cc476/1557247911674/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Harte+KONTAKTLINSE+auf+HORNNHAUT%2C+Foto+Florence+MALET_OHNE+Text_jpg6_10+LINK+Bildchen_.jpg D-BLICK auf ... KONTAKTLINSEN Eine kleine formstabile Kontaktlinse auf der Hornhaut https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596e246ce3df2818623302a6/1557247911757/ D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd05860f9619a517dd0c9e9/1557247911689/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+must+be+fitted+-+there+is+no+one+fits+for+all_Kontaktlinsen+m%C3%BCssen+angepasst+werden+und+nicht+von+der+Stange+gekauft+werden_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596a540b6f4ca3a637ba5e34/1557247911650/OSCB-Bild_9_Contact+Lenses_CARTOONS+vs.+BRILLE+...+Vielleicht+sollte+ich+mir+das+mit+den+Kontdaktlinsen+noch+mal+%C3%BCberlegen...++%28eay.cc+2011+1+%29.gif D-BLICK auf ... KONTAKTLINSEN Hier ist eine Zeichnung die natürlich einen sehr subjektiven Blick auf den potentiellen kosmetischen Vorteil einer Brille darstellt. (Dieser Cartoon ist oft zu sehen auf verschiedenen Internetseiten ... aber bisher war es uns unmöglich, den originalen Autor herauszufinden) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd082fde4966b67f4ddbdf7/1557247911664/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+REPLACEMENT+SCHEDULE_Kontaktlinsen+ERSATZ+Fahrplan%2C+Monatslinsen%2C+Tageslinsen_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd2a37571c10be8d01eec46/1557308286235/%28c%29-by-OSCB-Berlin.org_ENK-Erich-u-Nadja-Knop%2C-LIDER-%28FRONTAL%29-ANIMATION_HOW+TO+REBOVE+A+CONTACT+LENS_-Wie+kann+man+eine+KONTAKTLINSE+HERAUSNEHMEN_Kontaktlinse-weiche-Corneoscleral_400-9-0%2C35_.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd3d3d3e5e5f02b9aebb7a1/1557386200654/Otto+Wichterle%2C+hat+aus+HEMA+die+ersten+weichen+Kontaktlinsen+hergestellt_OPT+Sepia_.jpg D-BLICK auf ... KONTAKTLINSEN Otto Wichterle (1913 - 1998) gilt als Erfinder der ersten weichen Kontaktlinse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea83a62994ca304ac06737/1556970276816/ D-BLICK auf ... KONTAKTLINSEN KONTAKTLINSEN befinden sich mitten in der Funktionseinheit der Augenoberfläche und stehen damit in ´Berührung´ allen Komponenten der Augenoberfläche - vom Tränenfilm bis zu den Geweben - was Vor- und Nachteile haben kann. Hier ist eine mittelgrosse weiche korneosklerale Kontaktlinse dargestellt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b0f0473f5c000182bcfb/1557247911669/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses%2C+Kontaktlinsen+Vorgewachsenes+RANDSCHLINGENNETZ+der+Hornhaut_20_.jpg D-BLICK auf ... KONTAKTLINSEN Bei Sauerstoffmangel der Hornhaut durch eine daraufliegende Kontaktlinse wachsen die Gefässe des Randschlingennetz vom Hornhautrand zur Mitte vor https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599da6debebafb36847c0464/1557247911647/OSCB-Berlin.org_Hornhaut--KORNEA-und-Bindehaut--KONJUNKTIVA-von-der-Seite%2C-mit-harter-KONTAKTLINSE-auf-der-Kornea_FOTO%3B-Florence-MALET_.gif D-BLICK auf ... KONTAKTLINSEN Kontaktlinsen sitzen bzw. schwimmen direkt auf der Augenoberfläche - hier eine formstabile / “harte” Kontaktlinse auf der Hornhaut. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccda338419202f5ac087ffc/1557675658305/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_MIKROBEN-auf-Kontaktlinsen-k%C3%B6nnen-sich-verstecken-in-protektiven-BIOFILMEN.gif D-BLICK auf ... KONTAKTLINSEN Mikroorganismen bilden auf Kontaktlinsen (und auch in den Aufbewahrungsbehältern ! ) einen Biofilm in dem sie sich verbergen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdc6127c830251f14b5940c/1557946672823/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+must+CLEANED+and+DISINFECTED_Kontaktlinsen+m%C3%BCssen+GEREINIGT+und+DESINFIZIERT+werden+2+NEUTRALISIERUNG_30_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3c2c40a362c71aa3341673/1597779211936/OSCB-Berlin.org_Kontaktlinse+auf+Finger+FRAGEZEICHEN_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd0574b971a181302433a3b/1557247911681/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses+Rote+Kaninchenaugen+bei+Kontaktlinsen_20%2C+80%25_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599da341be6594696a92f34b/1557247911678/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif D-BLICK auf ... KONTAKTLINSEN Eine “weiche” flexible Hydrogel Kontaktlinse schwimmt im Tränenfilm und wird beim Lidschlag bewegt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cbc547a08522968ec2ca25f/1557247911659/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen%2C+WEICHE+Flexible+Hydrogel+Kontaktlinsen+auf+FINGER+%28Richtig+und+Falsch+herum%29_20_.jpg D-BLICK auf ... KONTAKTLINSEN “Weiche” flexible Kontaktlinsen haben normalerweise die Form einer Suppenschüssel mit den Rändern nach oben. Sie können aber leicht umklappen und bilden dann einen scharfen Rand zur Seite - was eher einem Suppenteller ähnelt (unten) - kein Problem, einfach wieder zurück klappen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd3297724a694ac621b2aa4/1557342639130/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses%2C+Kontaktlinsen_Trockenes+Auge%2C+ROTES+AUGE%2C+Konjunktivale+Injektion+mit+weicher+KONTAKTLINSE_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/605b7308e2b8342bf4f4d1a0/1616605972213/OSCB-Berlin.org_SKLERALE-Kontaktlinsen-erzeugen-eine-PROTEKTIVE-ZONE-zur-HEILUNG_.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/605b764e3b1fad4672e4e94b/1616606806671/OSCB-Berlin.org_Wichtige-INDIKATIONEN-f%C3%BCr-SKLERALE-KONTAKTLINSEN.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdc5b201905f4bfdd4edce9/1557945138182/%28c%29-OSCB%2C-ENK-Erich-und-Nadja-KNOP_CONTACT-LENS-CLEANING-and-DISINFECTION_-ANIMATION-Kontaktlinsen-REINIGUNG-und-DESINFEKTION-2__600-4-0%2C3.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd27b63f9619a926d412c51/1557298025839/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_SILICONE+Contact+Lenses%2C+SILIKON+Kontaktlinsen_20_.jpg D-BLICK auf ... KONTAKTLINSEN Prinzipieller Aufbau einer Silikon Hydrogel Kontaktlinse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f86d9eef77fc0275059948a/1602673152419/OSCB-Berlin.org_Interaktion-einer-KONTAKTLINSE-mit-der-HINTEREN-LIDKANTE.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/605b7e28e2b8342bf4f647d4/1616608849861/OSCB--Berlin.org-%28c%29-ENK_Konstruktion+einer+SKLERALEN+KONTAKTLINSE%2C+Sklerallinse_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ccde82890e5120001e77f8c/1557247911652/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_HARD+vs.+SOFT+Contact+Lenses%2C+WEICHE+Flexible+Hydrogel++VS.++HARTE+Kontaktlinsen+auf+FINGER+_.jpg D-BLICK auf ... KONTAKTLINSEN Sogenannte “Weiche” Kontaktlinsen (links) sind heute am weitesten verbreitet. Sie sind etwas grösser als “formstabile/ harte” Kontaktlinsen (rechts). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596e1d5115d5db84792951b2/1557247911754/ D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f86d4d5fca7701efa794a39/1602672148684/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Chronisch-Mechanische-Irritation-Epithelzellver%C3%A4nderungen-%28Plattenepithel-Metaplasie%29-der-Bulb%C3%A4ren-Konjunktiva.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1cfd5971a1838dfb50c32/1557254404805/LIDER-%28FRONTAL%29-ANIMATION-BLINZELN_-%2B-KONTAKTLINSE-WEICHE-Corneoscleral-FESTER_%C3%9Cberarbeitet_ogZ_500-18-0%2C15_.gif D-BLICK auf ... KONTAKTLINSEN mittelgrosse weiche Hydrogel Kontaktlinse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599da63be3df28bdb9a1bca9/1557247911693/OSCB-Berlin.org_HYGIENE-ist-ein-ENTSCHEIDENDER-FAKTOR-beim-KONTAKTLINSEN-TRAGEN_.gif D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea83a62994ca304ac06738/1556970581283/ D-BLICK auf ... KONTAKTLINSEN Viele interessante Ideen für die ZUKUNFT des Kontaktlinsentragens kursieren und befinden sich teilweise in der Entwicklung- Einige davon sind hier dargestellt(VON: lifeboat.com blog 2016 03 fish-and-insects-guide-design-for-future-contact-lenses - Posted by Klaus Baldauf) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1d13ae2c4837a222fbdc7/1557254502987/OSCB-GIF_ANIMATION+BLINK+%28FRONTAL%29+%2BCL+SCLERAL+17-8%2C+60-72_.gif D-BLICK auf ... KONTAKTLINSEN sehr grosse formstabile Sklerale Kontaktlinse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd3292863b3cb0001e6ed02/1557342531717/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Contact+Lenses%2C+Kontaktlinsen_Trockenes+Auge%2C+ROTES+AUGE%2C+LEICHTE+Konjunktivale+Injektion+mit+weicher+KONTAKTLINSE_20_.jpg D-BLICK auf ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea83a62994ca304ac06733/1483360052525/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif D-BLICK auf ... KONTAKTLINSEN https://oscb-berlin.org/d-blick-auf-meibomdruesen daily 0.75 2021-08-23 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599be5894c0dbf7a86c3acef/1503389077002/OSCB-Berlin.org_Die-Fette-der-MEIBOMDDR%C3%9CSEN-bilden-ein-klares-%C3%96L-bei-K%C3%B6rpertemperatur%2C-das-durch-die-Dr%C3%BCsen%C3%B6ffnung-auf-den-Lidrand-abgegeben-wird-%2B-DIAGNOSTISCHE-EXPRESSION.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968b3e73e00be71f93334b7/1500034032103/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/596893813e00be119f7eb2dc/1500025741126/OSCB-Berlin.org_Die-MEIBOMDR%C3%9CSEN-in-den-Augenlidern-produzieren-ein-D%C3%9CNNFL%C3%9CSSIGES-KLARES-%C3%96L.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968a3a7cf81e04b29891617/1500029872106/ D-BLICK auf ... MEIBOMDRÜSEN Die Drüsenkörper der MEIBOMDRÜSEN kann man durch die relativ durchsichtige Bindehaut/ Konjunktiva meist leicht erkennen, wenn das Augenlid (hier das untere) leicht nach aussen geklappt (Pfeil in B) wird. Die individuelle Öffnung jeder Drüse (in Abb. A u. B. markiert durch offene Pfeile) sind typischerweise in einer einzelnen Reihe angeordnet. Sie liegen sehr kurz vor dem Beginn der hinteren Lidkante und unmittelbar vor dem vorderen Rand des Tränenmeniskus, den man in Abb.C etwa in der Mitte des Unterlides als Lichtreflex erahnen kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c3c47d55b4135ade81c59/1503411280114/OSCB-BILD_2_MEIBOMDR%C3%9CSE-im-Lid%2C-3D-Zeichnung-KRSTIC%2C-%2BVERFREMDET-stark-%2B-DOPPELSCHATTEN-%2B-SPIEGELUNG-%2B-Zugeschnitten-%2B-OSCB.gif D-BLICK auf ... MEIBOMDRÜSEN Eine bekannte Zeichnung des Anatomen KRSTIC, die hier ´künstlerisch überarbeitet´ ist, zeigt, die Anordnung der rundlichen Azini der Meibomdrüsen, wie Zwiebeln in einem Zopf´, rund um einen zentralen Gang herum. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b2b19f14aa1676f42dab5/1503341350915/OSCB-Berlin.org_Der-LIDRAND-mit-den-MEIBOMDR%C3%9CSEN-in-klinischen-FOTOS.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599beb0803596ef973b3618d/1503390492951/OSCB-Berlin.org_DIAGNOSTISCHE-Expression-der-Meibomdr%C3%BCsen-mit-einem-standardisierten-Druckapplikator--%28Meibomian-Gland-Evaluator%2C-MGE%29.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599be38ae9bfdf34348e51cf/1503388564535/OSCB-Berlin.org_Die-%C3%96ffnungen-der-Meibomdr%C3%BCsen-sind-am-hinteren-Lidrand-sichtbar.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599bf3fe7131a5ca151d76fd/1503392778962/OSCB-Berlin.org_Die-Untersuchung-der-%C3%96L-SCHICHT-auf-dem-Tr%C3%A4nenfilm-und-der-Hornhaut-Topografie-ist-auch-mit-Handger%C3%A4ten-m%C3%B6glich-%28TearScope%29.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea8dc1725e255182faf8d9/1491980858692/OSCB-Bild_2_Meibomian+Gland_Schematic+STRUCTURE%2C+NORMAL+vs.+OBSTRUCTED+%28kurz%29+aus+Ophthalmologe+2009.png D-BLICK auf ... MEIBOMDRÜSEN Im Vergleich zu einer normalen Meibomdrüse (links) ist bei einer verstopften Meibomdrüse (rechts) die Ausschüttung von gebildetem Öl blockiert und daher führt der ansteigende Druck in der Drüse zu einer Erweiterung/ Dilatation des Gangsystems und zu einem Untergang/ Druck-Atrophie mit letztlicher Verkleinerung der rundlichen Drüsenendstücke. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5982058586e6c04a57ebda47/1501693324580/OSCB-Berlin.org_Meibom--%C3%96L--vermindert-die-Verdunstung-und-erlaubt-optimale-Licht-Brechung_3D_WEB%2C-EINZEL_HH-Neu_2.gif D-BLICK auf ... MEIBOMDRÜSEN Die HAUPTFUNKTIONEN der äußeren ÖL-SCHICHT des Tränenfilms sind (1) die Verminderung der Verdunstung der wässrigen Phase der Tränen durch Abdeckung des warmen Tränenfilms gegen die Außenluft, sowie (2) die Herstellung einer sehr dünnen, gleichmäßigen und glatten Oberfläche, die als Luft-Tränenfilm-Grenze einen Hauptteil (ca. 2/3) der Lichtbrechungskraft des Auges ausmacht. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/597503281e5b6c34b275dfd3/1500840756654/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5967c7eb72af65139178f784/1499973623188/ D-BLICK auf ... MEIBOMDRÜSEN Zahlreiche einzelne Meibomdrüsen (gelb) befinden sich in den Tarsalplatten von Ober- und Unterlid, die der Verstärkung der Lider dienen, und füllen diese weitgehend aus. Damit liegen sie Meibomdrüsen recht verborgen und sind den üblichen klinischen Untersuchungstechniken meist verborgen. Vor allem ihre Ausführungsgangöffnungen sind als kleine Punkte weit hinten am Lidrand erkennbar. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598211236a4963113527bd8c/1501696361281/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599bfb88914e6bb960c8cd2f/1503395136847/GIF+Animation_Typische+Symptome+beim+Trockenen+Auge_Bild+4v4_48-72_4-0.5fps_.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968f0da46c3c428c043a0e5/1500049646658/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599bd3dbbe6594b53575e1d0/1503384559742/OSCB-Berlin.org_Die-%C3%96ffnungen-der-Meibomdr%C3%BCsen-sind-am-hinteren-Lidrand-sichtbar.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5caa231f9140b7d3bde98fb9/1554653992959/Aufbau+einer+MEIBOMDR%C3%9CSE_OSCB-Berlin.org%2C+%28c%29+Erich+%26+Nadja+Knop+ENK__.jpg D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b0385d482e944d53988df/1503331228285/GIF_Nur+der+d%C3%BCnne+homogene+Tr%C3%A4nen-FILMgarantiert+Gesundheit+und+Scharfes+SEHEN_BULBUS-3D-%2B-TRF-3D-%2BRetina_JPG-aus-PPT_8-2_.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59689f21099c01e15ea4fc17/1500028713859/ D-BLICK auf ... MEIBOMDRÜSEN Die ausgedehnten langen Drüsenkörper der MEIBOMDRÜSEN füllen die gesamte bindegewebige Tarsalplatte im Ober- und Unterlid. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59710d17914e6bca35f411c2/1500581161005/ D-BLICK auf ... MEIBOMDRÜSEN Die Bildung des Meibom-Öls tief in den Drüsen innerhalb des Augenlides muss unterschieden werden von der späteren Ausschüttung des Öls nach aussen auf den Lidrand. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b098cb8a79b7ac37807f5/1503332772858/OSCB-GIF_4.7_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_TFLL+LIPID+LAYER+INTERFEROMETRY+BREAK+UP+36-12+GIF.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea8dc1725e255182faf8d4/1486817715104/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c298d46c3c42867a5e2a5/1503406486249/OSCB-Berlin.org_HISTOLOGISCHER-AUFBAU-der-MEIBOMDR%C3%9CSEN-Lidrand-und-Ausf%C3%BChrungsgang_HOCHKANT-%2B-grosser-PFEIL.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599bf814c534a5c068e0ea63/1503393824550/OSCB-Berlin.org_Aufbau-der-Tr%C3%A4nen-FILM-LIPID-SCHICHT-%28TFLS%29-auf-dem-w%C3%A4ssrigen-Tr%C3%A4nenfilm.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59836b12ff7c50bf49913cc1/1501784859603/OSCB-Berlin.org_Meibom--%C3%96L--vermindert-die-Verdunstung-und-erlaubt-optimale-Licht-Brechung_3D-Einzel_WEB_.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5972479615d5dbd049677884/1500661673361/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b266ebe42d6985534113e/1503340154271/OSCB-Berlin.org_INTERFEROMETRISCHE-ANALYSE-des-%C3%96l-FILM-der-Tr%C3%A4nen-%28Tr%C3%A4nen-Film-LIPID-Schicht---TFLS%29_Tear-Science-LIPIVIEW_.gif D-BLICK auf ... MEIBOMDRÜSEN In der Interferometrischen Messung ist oben eine normal dicke Tränenfilm-Lipidschicht sichtbar mit goldenen bis blauen Interferenz-Farben (Dicke ca. 90nm). Im unteren Bild ist ein Tränenfilm mit zu dünner Ölschicht in grauen Farben (Dicke ca. 35nm). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b2b6ebe6594d3c855a64c/1503341438306/OSCB-Berlin.org_ANATOMIE-der-MEIBOMDR%C3%9CSEN.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5984634b37c5816a68174c37/1501848403154/ D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599d2cdb9f745681a73e760f/1503472866892/OSCB-Berlin.org_Meibom--%C3%96L--vermindert-die-Verdunstung-und-erlaubt-optimale-Licht-Brechung_3D-%C3%9Cbersicht-mit-%C3%96L-TROPFEN_WEB-%2816%29_3.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5968c44a725e25d17c0bbfa7/1500038227429/ D-BLICK auf ... MEIBOMDRÜSEN Ein kugeliges Endstück/ Azinus am ´Ende´ des Gangsystems tief im Gewebe des Augenlides. Es ist dicht gefüllt mit den Öl-bildenden Zellen (Meibozyten). Sie bilden zuerst Lipide und häufen sie in den Zellen an, wobei sie dabei stark wachsen (´Reifung´). Dabei wandern sie vom Rand zur Mitte des Endstücks (Pfeile). Schliesslich zerfallen sie und setzen das Öl in das Gangsystem frei. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598200e0e45a7caf4c3e1902/1501692138305/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-2x-3D-%C3%96L_NEU-WEB.gif D-BLICK auf ... MEIBOMDRÜSEN Der TRÄNENFILM vor der transparenten Hornhaut (Prä-kornealer Tränenfilm) hat einen geschichteten Aufbau, wobei meist drei Schichten unterschieden werden. (1) Außen zur Luft liegt eine dünne Schicht aus dem Öl (gelb) der Meibomdrüsen. Sie bedeckt (2) die wässrige Hauptphase des Tränenfilms, die vermutlich überwiegend vermischt ist mit den Schleimstoffen (Muzine), die auch in konzentrierter Form (3) die innere Muzinschicht (pink) auf den Epithelzellen der Augenoberfläche bilden. Die Lipidschicht ist hier in der schematischen Zeichnung relativ viel zu dick im Vergleich zur Gesamtdicke des Tränenfilms angegeben - in der natürlichen Grössen-Relation könnte man die Lipidschicht im Querschnitt allerdings praktisch nicht darstellen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599b04d77131a5eedc6b683c/1503331570224/OSCB-GIF_MEIBOM+DANCING+%26+OSCB-Berlin%2C+ENK_15cm-72_3-1.5fps_.gif D-BLICK auf ... MEIBOMDRÜSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599c2ff4c534a5c068e329f3/1503408128924/OSCB-Berlin.org_Histologischer-Aufbau-der-Meibomdr%C3%BCsen%2C-Zentraler-Gang%2C-Verbindungsgang%2C-Azinus_QUER%2C-Neu%2C_35cm.gif D-BLICK auf ... MEIBOMDRÜSEN Histologischer Flachschnitt durch eine Meibomdrüse, sie ist etwa in der Mitte getroffen in Höhe des zentralen Ganges. Von dort gehen zahlreiche kleine Verbindungsgänge zu den Seiten, wo die Öl-produzierenden Zellen (Meibozyten) in den rundlichen sekretorischen Azini liegen. Das Sekret fliesst von dort durch die Verbindungsgänge in den zentralen Gang in Richtung der Drüsenöffnung (hier oben gelegen) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea8dc1725e255182faf8cf/1485864580335/MEIBOMDR%C3%9CSE%2C+Normal+%28EIGENE+Zeichnung+Ophthalmologe+2009%29_LIEGT+quer+f%C3%BCr+BANNER+f%C3%BCr+OSCB+Homepage_20cm-72_%2BENK%2BOSCB%2C+Sauber%2BSCHMALER_.png D-BLICK auf ... MEIBOMDRÜSEN https://oscb-berlin.org/d-blick-auf-mdd daily 0.75 2020-11-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598d5a6e7131a504d244b959/1502435958228/ D-BLICK auf ... MDD Bei der Störung der Meibomdrüsen in den Augenlider, der Meibomdrüsen Dysfunktion (MDD) besteht typischerweise eine Drüsenverstopfung. Diese ist hier am leicht auswärts gewendeten Oberlid erkennbar durch mit weisslichem Sekret verstopfte und etwas vorgewölbte Drüsenöffnungen am Lidrand. Durch den Ölmangel und das hierdurch ausgelöste Trockene Auge sind die Augenbindehaut und auch der Lidrand leicht gereizt und damit gerötet. --- Bei leichtem Druck kann sich verändertes Sekret entleeren (unten). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598dc869cd0f6843f2c41e73/1502464121860/OSCB-Berlin.org_INTERFEROMETRISCHE-ANALYSIE-des-%C3%96l-FILM-der-Tr%C3%A4nen-%28Tr%C3%A4nen-Film-LIPID-Schicht---TFLS%29_Tear-Science-LIPIVIEW_.gif D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c3a2903596e819cab1911/1502362168534/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f87e3a0411d6a8c861c7/1502214279330/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599af789197aeae63176ff3b/1605291337632/OSCB-Berlin.org_HISTOLOGIE-der-OBSTRUKTIVEN--Meibomdr%C3%BCsen-Dysfunktion-%28MDD%2C-MGD%29_Ophthalmologie-2009%2C-IOVS-2011%29.gif D-BLICK auf ... MDD Die MIKROSKOPISCHE UNTERSUCHUNG einer verstopften Meibomdrüse zeigt degenerative Zeichen wie eine Dilatation des Gangsystems (Zentraler Gang, cd) und ein Verschwinden der Öl-bildenden Zellen (*) in den Endstücken. Der mutmassliche MECHANISMUS der Schäigung in einer verstopften Meibomdrüse ist in der nachfolgenden schematischen Animation gezeigt. Der erhöhte Druck führt zu eiiner Erweiterung der Drüsengänge und zu einer Druckatrophie (´Pressure Atrophy´) mit Untergang der Öl-bildenden Zellen (Meibozyten, hier gelb). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598d873d1e5b6c81cf93c05d/1502447467309/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599ae954e3df28a29d6193ec/1503324518341/GIF-ANIMATION-HAUPT-PATHOLOGIEN-bei-MGD_%C3%96L-Mangel+mt+erh%C3%B6hter+TR%C3%84NENVERDUNSTUNG+und+DR%C3%9CSENZERST%C3%96RUNG+_DEUTSCH.gif D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c303ae4fcb5d2ad5f3dfa/1502359621452/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction+%28MGD%29+-+Clinical+Images+of+typical+Inspissated+Secretum+in+MGD+Patients%2C+Cornea+2010+%2B+Ophthalmologe+2009.png D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea9196ebbd1a8c72c09f35/1486738257418/ D-BLICK auf ... MDD Die Zusammenfassungs-Abbildung des TFOS MGD Workshop fasst die Hauptfaktoren bei der Krankheitsentwicklung der MDD zusammen und erklärt daher welche Faktoren zum Auftreten und bei der Verschlimmerung der Erkrankung beteiligt sind und wie sich diese Faktoren dabei gegenseitig beeinflussen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f0c01e5b6cbabc94b101/1502212303779/ D-BLICK auf ... MDD Feuchte Wärmung ist, bei regelmässiger täglicher Anwendung, eine aussichtsreiche Therapiemethode bei Meibomdrüsenverstopfung, die Patienten selbst durchführen können. Um über 10 Minuten eine ausreichend hohe Temperatur zu erreichen, muss die heisse Kompresse allerdings (nach Studien von Blackie und Korb) alle 2 Minuten durch eine neue heisse ersetzt werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a5c6df37c5810f8dc9111e/1504036647700/HAMLET-Monolog-SEINE-oder-NICHTsein-%28WIKIPEDIA%29_WEB_.gif D-BLICK auf ... MDD HamletSkullHCSealous.jpg - Wikimedia https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5984944703596eaddbfd0303/1501860976423/ D-BLICK auf ... MDD Bei einem ÖL-MANGEL bleibt der wässrige Tränenfilm nur kurz stabil, bevor er aufbricht. Dann liegt das Gewebe frei an der Aussenluft und kann geschädigt werden (siehe nächste Abbildung) wenn nicht ein neuer Lidschlag stattfindet, der einen neuen Tränenfilm ausbreitet. Ein normaler Tränenfilm muss mindestens zehn Sekunden stabil bleiben - hier dagegen ist der nur knapp 2 Sekunden stabil. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f4b9e4fcb565bf845eb3/1502213318723/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598463ad9f745676d8af61d1/1501848514930/ D-BLICK auf ... MDD Typisches Zeichen einer Verstopfenden OBSTRUKTIVEN MGD sind Vorwölbungen von eingedicktem und oft verhärtetem Sekret, das wie ein Pfropfen aus den kleinen Öffnungen der Meibomdrüsen am hinteren Lidrdand nach aussen ragt. Teils sind diese Sekretpfropfen überdeckt von einer Art Membran aus Epithelzellen (Abbildung rechts) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598496b1579fb366729d8acd/1501861585687/ D-BLICK auf ... MDD Die schematische Animation zeigt, dass bei einem Ölmangel der wässrige Tränenfilm nur kurz (hier knapp 2 Sekunden) stabil bleibt bevor er aufbricht und das Gewebe frei liegt an der Aussenluft. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f15a8419c293e18466f9/1502212478821/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c2e37ebbd1a5963bf0dc7/1502359108917/OSCB-Berlin.org_Einfluss-von-Kontaktlinsen-auf-die-Meibomdr%C3%BCsen-Dysfunktion-%28MDD%2C-MGD%29.gif D-BLICK auf ... MDD Kontaktlinsen und Entzündungen der Konjunktiva des Augenlides können die Meibomdrüsen schädigen. Kontaktlinsen sind im Bereiche der tarsalen Konjunktiva des Lides (Abb. links) nur durch eine sehr dünne Gewebeschicht von den etwas tiefer im Lid liegenden Meibomdrüsen getrennt (Abb. Mitte). Langjähriges Kontaktlinsen-Tragen und auch entzündliche Erkrankungen der Konjunktiva (Allergische Konjunktivitis) können einen deutlichen schädigenden Einfluss auf die Meibomdrüsen haben, mit einem Verschwinden von Drüsengewebe in der Beobachtungstechnik der Meibographie. Daher darf man annehmen, dass sowohl mechanische Reibung durch die Kontaktlinse und vor allem ihren Rand, wie auch chemische Reize in Sinne der Entzündungsmediatoren, die bei Entzündlichen Erkrankungen entstehen und Entzündungsreaktion weiter verstärken, von der Konjunktiva durch die sehr schmale trennende Gewebeschicht zu den Meibomdrüsen vordringen können (Abb. rechts). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598af274cf81e028a0405a75/1502278277552/ D-BLICK auf ... MDD Als THERAPIE-OPTIONEN bei der Meibomdrüsen-Dysfunktion (MDD) bieten sich, neben einer Ergänzung des fehlenden Öls durch Lipid Substitution, die eine sofortige Linderung der Symptome verschafft, Massnahmen der Physikalische Therapie mit Wärmung und Auspressung der verstopften Drüsen an. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5984927d15d5dbb2e643d3b9/1501860490535/ D-BLICK auf ... MDD Bei der Störung der Meibomdrüsen in den Augenlider, der Meibomdrüsen Dysfunktion (MDD) besteht typischerweise eine Drüsenverstopfung. Diese ist hier am leicht auswärts gewendeten Oberlid erkennbar durch mit weisslichem Sekret verstopfte und etwas vorgewölbte Drüsenöffnungen am Lidrand. Durch den Ölmangel und das hierdurch ausgelöste Trockene Auge sind die Augenbindehaut und auch der Lidrand leicht gereizt und damit gerötet. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f3f0bebafb782fb8d36f/1502213114796/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59981bf3d7bdcede8ce7c74f/1503140874384/OSCB-Berlin.org_Einige-THERAPIE-Optionen--bei--Meibomdr%C3%BCsen-Dysfunktion-%28MDD%29_Lipid-Substitution-%2B-Physikalische-Therapie.gif D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c0dfb4c0dbf58c6d82060/1502350857801/ D-BLICK auf ... MDD Durch Druck auf ein Augenlid mit verstopften Meibomdrüsen bei MDD kann sich verändertes eingedicktes Sekret aus den kleinen Drüsenöffnungen am hinteren Lidrand entleeren. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598dc8bfe45a7c6e08c289a3/1502464199417/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989808d3a041189e769ae4a/1502183582872/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989b9e8cd39c3ced747d33e/1502198260530/ D-BLICK auf ... MDD Der Lidrand sollte bei Meibomdrüsen-Dysfunktion regelmässig, mindestens täglich, durch sanfte Massage mit einem Reinigungstuch von Auflagerungen aus Resten von verändertem Öl und Bakterien befreit werdenDies ist besonders sinnvoll nach vorheriger feuchter Wärmung zur Verflüssigung des eingedickten Öls in den Drüsen, das dabei vorsichtig mit heraus massiert wird, https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598aff158419c293e192d65f/1606572468921/ D-BLICK auf ... MDD Bei der UNAUFFÄLLIGEN/ VERBORGENEN MDD (NON-OBVIOUS MDD -NOMGD) sieht der Lidrand typischerweise recht normal aus (Abb. oben) und hierbei gibt es (noch) keine Symptome weil die Lipidmenge aus den anderen Drüsen insgesamt noch ausreichend ist. Nur wenn ein leichter Druck von außen auf den Lidrand ausgeübt wird durch eine "DIAGNOSTISCHE Drüsen-EXPRESSION" (Abb. Mitte mit dem kalibrierten MGE Druckapplikator) kann man erkennen, ob sich normales klares, flüssiges Meibomöl aus den Drüsenöffnungen entleert - die Drüse also noch aktiv ist. Wenn dies nicht der Fall ist dann ist die Drüse nicht aktiv, was dann meist durch eine Verstopfung/Obstruktion bedingt ist. Solch eine Drüsen-Verstopfung ist die typische Ursache für die MDD und sollte dann durch eine Auspressung mit starkem Druck (z.B. zwischen zwei Spateln oder gegen eine Lidplatte) beseitigt werden - dies ist eine THERAPEUTISCHE EXPRESSION. Oft kann dann stark verändertes und verdicktes Sekret mit Zahnpasta-artiger Konsistenz herausgepresst werden (Abb. unten). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5984a5d24c0dbf624a2dadb6/1501865430687/ D-BLICK auf ... MDD Auch wenn die Menge der wässrigen Tränen normal ist, löst der Öl-Mangel durch die Störung der Meibomdrüsen einen Tränenmangel mit einer Sequenz von verschieden weiteren ´Sekundären Pathogenetischen Faktoren´ aus. Diese beeinflussen sich gegenseitig und bestehen aus z.B.: Tränenfilm-Instabilität, Benetzungsstörungen mit Entstehung Trocken Stellen auf der Hornhaut, Erhöhter Reibung, verstärkter Verdunstung. Die beiden entscheidenden Sekundären pathogenetischen Faktoren scheinen eine chronische Mechanische Reizung des Gewebes zu sein sowie eine erhöhte Konzentration der Salze in verbleibenden Tränen (Hyperosmolarität). Beide Faktoren können zur Schädigung des Gewebes der Augenoberfläche führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598ae248a803bb87a9055c09/1502274132589/ D-BLICK auf ... MDD Bei einem Verschluss der Drüsenöffnung auf dem hinteren Lidrand kommt es, durch die ständige Produktion von weiterem öligem Sekret in den Drüsenendstücken, zur nachfolgenden Ansammlung von Sekret in der Drüse und dadurch zu einer Erhöhung des Drucks in der Drüse und nachfolgender Schädigung des Drüsengewebes bis zur Zerstörung. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c14e7d7bdceefb4b50e99/1502352628073/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598b059bdb29d6084ce2f56e/1502283183786/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598d66f1ff7c50fa2d55b059/1502439169174/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f32b914e6b5b5959898f/1544376690020/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f58be3df28c8a4752a72/1502213526686/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59871a30ebbd1aa41431687c/1597573164595/OSCB-Berlin.org_%C3%96L-Mangel-bei-Meibomdr%C3%BCsen-Dysfunktion-f%C3%BChrt-zu-Instabilem-Tr%C3%A4nenfilm-mit-erh%C3%B6hter-Verdunstung-und-nachfolgenden-Evaporativen-TROCKENE-AUGE_2.gif D-BLICK auf ... MDD ÖL-MANGEL des TRÄNENFILMS schädigt den Tränenfilm und die Augenoberfläche. Selbst wenn ausreichend wässrige Tränen vorhanden sind, führt ein Mangel der Ölschicht (obere gelbe Schicht auf dem blauen Tränenfilm) durch eine Störung der Meibomdrüsen zu Instabilität mit frühzeitigem Zusammenbrechen des Tränenfilms mit vermehrter Verdunstung des Tränenwassers. Die Konzentration von Salzen und Proteinen (graue Partikel) erhöht sich in der verbleibenden Tränenmenge, was einen schädlichen Reiz für die Epithelzellen darstellt. Dies führt letztlich zur Schädigung der empfindlichen Epithel-Zellen der Augenoberfläche. Wenn Zellen zerstört werden entstehen Lücken im Gewebe und Fremdstoffe, einschliesslich von Bakterien und Viren, haben freien Zugang zum Körper. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598d5aa93e00be8deb291626/1502436018847/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598b0f3ea803bb87a9074f89/1597585830346/ D-BLICK auf ... MDD Die beiden PATHOGENETISCHEN HAUPTFAKTOREN der MDD sind hier gezeigt zusammen mit ihren Konsequenzen. EINGEDICKTES SEKRET mit erhöhtem Schmelzpunkt, das durch das Auftreten von Lipid-Veränderungen entsteht, sowie eine HYPER-KERATINISIERUNG des Epithels in den Drüsengängenund auf dem Lidrand führen zur VERSTOPFUNG der Meibomdrüsen. Wesentliche KONSEQUENZEN der Verstopfung sind (1) LIPIDMANGEL auf dem Lidrand und Tränenfilm, der zum Tränenmangel und damit zum Trockenen Auge führt - sowie (2) ein ERHÖHTER DRUCK in den Meibomdrüsen durch Sekretaufstau. Dieser führt zu einer Erweiterung des Gangsystems und zur Druckschädigung der Lipid bildenden Sekretorischen Zellen in den rundlichen Endstücken ... und zu einem nachfolgenden Untergang von funktionellem Drüsengewebe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59871cfc9f74566cc77b234a/1502027027647/ D-BLICK auf ... MDD ÖL-MANGEL auf dem TRÄNENFILM und seine FOLGEN. Mangel von ÖL (gelbe Oberflächenschicht) auf dem Tränenfilm (blau) führt zu erhöhter Verdunstung des Tränenwassers mit einem, ganz oder nur lokal, dünneren Tränenfilm. Durch die erhöhte Konzentration der gelösten Salze und Proteine (kleine graue Partikel) in den verbleibenden Tränen kommt es zur sogenannten Hyper-Osmolarität der Tränen. Dieses konzentrierte Salzmilieu schädigt die empfindliche Oberflächenstruktur der fingerartigen Zellfortsätze (Mikrovilli) auf den Epithel-Zellen und reizt die Zellen zu Entzündungsreaktionen. Wenn diese Schädigung ausgeprägt ist, können die Zellen auch zerstört werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faecafd1cc5cc66226f438a/1605291468311/OSCB-Berlin.org+%28c%29+ENK_Bild_2_Meibomian+Gland_Histology+of+Obstructive+Meibomian+Gland+Dysfunction+%28MGD%29+Ophthalmologe+2009_OT_15_.jpg D-BLICK auf ... MDD Histologische Studien des Forschungszentrum für die Augenoberfläche Berlin (OSCB) haben einige typische Veränderungen der Meibomdrüsen bei MGD (rechts) im Vergleich zu normalen Drüsen (links) ergeben. Dabei handelt es sich um eine Obstruktion der Mündung durch keratinisiertes Material (oben rechts) und Anzeichen einer Drüsenatrophie (unten rechts). Dies wird für das höher aufgelöste Bild unten genauer erklärt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c4207bebafb811d5721a3/1502364181133/ D-BLICK auf ... MDD ÜBERSCHIESSENDES BAKTERIENWACHSTUM (Bakterielle Kolonisierung) des Lidrandes und vermutlich auch der Meibomdrüsen erscheint als wichtiger pathogenetischer Faktor bei der MDD. Sie ruft durch die Produktion Lipid-zersetzender Bakterienenzyme eine Veränderung der normalen Meibom Lipide hervor, was zu Gewebe-reizenden Lipiden führt. Diese können eine chronische Sub-klinische Entzündung auslösen, die im Weiteren zu einer verstärkte Verhornung des Epithels führen kann. Verhornung ist, wie beschrieben, ein bedeutender Ko-Faktor für die Verstopfung der Meibomdrüsen, die zu einer Stase und Ansammlung des Sekretes in der Drüse führt. Dies wiederum befördert typischerweise das Wachstum von Bakterien . Die beschriebenen Zusammenhänge stellen damit insgesamt einen selbstverstärkenden Teufelskreis dar, der eine chronische Erkrankung mit Selbstverschlimmerung aufrecht erhalten kann ... wenn dieses nicht durch eine Therapie (siehe dazu im Text) unterbrochen wird. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598993c5914e6b1524b90384/1502188492135/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59849044f7e0ab6f61df4054/1501859916102/OSCB-Berlin.org_%C3%96L-Mangel-bei-Meibomdr%C3%BCsen-Dysfunktion-f%C3%BChrt-zu-Instabilem-Tr%C3%A4nenfilm-mit-erh%C3%B6hter-Verdunstung-und-nachfolgenden-Evaporativen-TROCKENE-AUGE.gif D-BLICK auf ... MDD Die MEIBOMDRÜSEN DYSFUNKTION (MDD) führt zum Evaporativen Trockenen Auge, welches gleichzeitig die häufigste primäre Ursache (bei etwa vier von fünf Patienten) der Erkrankung des TROCKENEN AUGES darstellt. Selbst wenn ausreichend wässrige Tränen vorhanden sind (rechts) führt ein Ölmangel (links) durch eine Störung der Meibomdrüsen zu Instabilität, frühzeitigem Zusammenbrechen und vermehrter Verdunstung des Tränenfilms. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c35fad482e959b9cb3813/1502361092166/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f8088419c293e184e181/1502214185840/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f36a10e470e7762c6780401/1597415707091/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_MGD%2C+MEIBOGRAPHY_ARITA+2008%2C+Non-Contact+MEIBOGRAPHY+with+Infrared+Illumination+-+AUFNAHME+SITUATION+mit+Patient.png D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598c1e963e00beaec71cb9cd/1502355103989/ D-BLICK auf ... MDD Der leichte Druck mit dem Finger von aussen auf den Lidrand(DIAGNOSTISCHE EXPRESSION (Offener Pfeil) ist der einfachste und sicherste Test für die intakte FUNKTION der Meibomdrüsen. Eine gesunde Drüse gibt dann ein kleines Tröpfchen dünnflüssiges, klares Öl ab, das eine kleine Pfütze um die Drüsenöffnung bildet (kleiner Pfeil) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59981d33e45a7cd2ba47d8e0/1503141188043/OSCB-Berlin.org_Meibomdr%C3%BCsen-Dysfunktion-%28MDD%29-mit-verstopften-und-irregul%C3%A4ren-%C3%96ffnungen-eingedicktes-Sekret-wird-ausgepresst.gif D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5989f1ab17bffc79a0b7b9ad/1502212535013/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59845e85d482e94a17e71577/1501847180524/ D-BLICK auf ... MDD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/598b6364893fc0b89356ccf8/1502307333071/GIF-Animation_Meibomian-Gland-Dysfunction-%28MGD-MDD%29_AUSPRESSUNG-des-Lides-mit-dem-FINGER_DEUTSCH_Einzel-BILDER_8-2_.gif D-BLICK auf ... MDD Blick von oben auf ein Unterlid bei AUSPRESSUNG der Meibomdrüsen. Bei verstopften Meibomdrüsen kann es sinnvoll ein, zusätzlich zu einer sanften Lidmasssage, das Augenlid zwischen 2 Fingern vorsichtig auszupressen. Dies ist am einfachsten nach einer feuchten Wärmung, wenn verhärtetes Sekret in den Drüsen wieder flüssiger geworden ist. Eine Reinigung des Lidrandes durch ´Lidrandhygiene´ sollte sich anschliessen (folgende Abbildung). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea9196ebbd1a8c72c09f33/1485863161896/OSCB-GIF_MEIBOMDR%C3%9CSE%2C+Normal+%2B+Obstruktion+%28Ophthalmologe+2009%29_LIEGT+quer%2C+CROP+oben+f%C3%BCr+Banner_20-72_2-1fps_.gif D-BLICK auf ... MDD https://oscb-berlin.org/d-ueberblick-ueber-den-lidrand daily 0.75 2020-12-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ceee66853450a2c644221ce/1607708146295/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Der+freie+LIDRAND+mit+Innerer+und+%C3%84usserer+LidKANTE%2C+KLINISCHE+FOTOS+%2B+Schemazeichnung+2_20_.jpg d-ÜBERBLICK über ...den LIDRAND Der FREIE LIDRAND zeigt zur geöffneten Lidspalte hin. Sie wird vorne begrenzt durch die runde vordere anteriore Lidkante (ALK) und hinten durch die scharfe hintere posteriore Lidkante (PLK), die den Augapfel/ Bulbus berührt und als Lid Wiper (Lidwischer) den Tränenfilm herstellt und aufrecht hält. Die Öffnungen der Meibomdrüsen auf den hinteren Lidrand sind markiert durch einen offenen Pfeil in der Abbildung rechts. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cef9d87e3332f000116a2e8/1607074627311/OSCB-Berlin.org_GIF-Animation_Typische-SYMTOME-beim-Trockenen-Auge_Bild-1-4v4_20-72_6-x2sec-PSE__.gif d-ÜBERBLICK über ...den LIDRAND Die gesamte Augenoberfläche ist ein integriertes Funktionssystem ... in dem alle Anteile funktionieren müssen um die Gesamtgesundheit und damit das scharfe Sehen zu erhalten. Störungen des Lidrandes, vor allem im Bereich der hinteren Lidkante können die Stabilität des Tränenfilms erheblich stören, da er (1) durch durch den Lid Wiper der hinteren Lidkante erst dünn und gleichmäßig hergestellt werden kann und (2) der Tränenfilm auf der hinteren Lidkante als Basis ruht. Bei Störungen der Lidkante kann ein Trockenes Auge eine typische Folge sein. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f7de5258346273050455bf9/1607074627308/OSCB-Bild_5.4.2_The+Lid+Margin_5.4.3_The+lid+wiper+has+a+BUILT-IN+LUBRICATION+SYSTEM+of+goblet+cells+aus+CORNEA+2012.png d-ÜBERBLICK über ...den LIDRAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cefa1ac4bfd160001634946/1607074627302/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Der+TR%C3%84NEN+MENISCUS+liegt+auf+der+MARX+LINIE+am+LIDRAND_20_.jpg d-ÜBERBLICK über ...den LIDRAND Der TRÄNENMENISKUS (blaue Pfeile in allen Schemazeichnungen) ist das deutlich verdickte ´ENDE´ des Tränenfilms, dort wo er den Lidrand berührt. Die Bildung des Tränenmeniskus (´Tränensee´), der mehr Tränenflüssigkeit enthält als der Tränenfilm selbst und im Querschnitt (Abb. links) etwa dreieckig ist, hängt mit der Oberflächenspannung zusammen. In starker Vergrößerung (Ausschnitte ganz rechts) erkennt man, dass der Tränenmeniskus auf der MARX´schen Linie liegt (rotbraune Pfeile, ganz links), die wiederum die Oberfläche der Haut-Schleimhaut-Grenze (MCJ) ist - Dies ist die vordere, erste Zone der hinteren Lidkante. Das Lid berührt mit der hinteren, zweiten, Zone den Augapfel/Bulbus - dort bildet die marginale Konjunktiva die verdickte Epithel-Lippe des Lid Wiper, der die Tränen zum sehr dünnen Tränenfilm auszieht. Die Lidränder des Auges auf der Schemazeichnung rechts sind leicht nach außen evertiert damit man den Lidrand komplett sehen kann, ganz hinten auf dem freien Lidrand liegen die Öffnungen der Meibomdrüsen, noch vor dem Tränenmeniskus. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea94ee37c5819161a23935/1559214008848/ d-ÜBERBLICK über ...den LIDRAND Als Hauptfunktion des LIDRANDES erscheint, abgesehen von einer Schutzfunktion, das MANAGEMENT der Tränenflüssigkeit auf dem Auge und seine Umwandlung in einen Tränen-FILM. (Der Tränenfluss in dieser schematischen Darstellung ist erhöht gegenüber dem Normalen und entspricht etwa dem beim Weinen) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cefb575439d550001d6fae4/1607708151582/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Der+freie+LIDRAND+mit+Innerer+und+%C3%84usserer+LidKANTE%2C+KLINISCHE+FOTOS+%2B+Schemazeichnung_20_.jpg d-ÜBERBLICK über ...den LIDRAND Der Lidrand in klinischen Fotos. Auf der vorderen Lidkante mit den Wimpern (Abbildung A, das Lid ist leicht evertiert) folgt der glatte Streifen des freien Lidrandes ohne Haare (vergleiche mit Abbildung rechts wo das Lid ist in Normalstellung ist). Der hintere Rand ist relativ scharf (offener Pfeil in Abbildung B, das Lid ist weit nach aussen gedreht) - normalerweise liegt es am Augapfel an wie in der Abbildung rechts. Die Meibom Drüsen scheinen als weißliche Streifen durch tarsale Bindehaut (in Abbildung B). Die Öffnungen der Drüsen auf den hinteren Lidrand sind als Linie kleiner Punkte nahe der hinteren Lidkante zu sehen (offener Pfeil in Abbildung A und B ). Sie sind in einer höheren Vergrößerung in einer nachfolgenden Abbildung zu sehen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cefaec543a1390001d0f395/1607074627305/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Der+LID+WIPER+%28Lidwischer%29+ist+eine+verdickte+Epithel-Lippe+am+LIDRAND+zur+Ausbreitung+des+Tr%C3%A4nenfilms_20_.jpg d-ÜBERBLICK über ...den LIDRAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ceed98be4966b9921b91d03/1607074627291/OSCB-Berlin.org_%28c%29+ENK-+Erich+und+Nadja+Knop_DER+LIDRAND%2C+Schemazeichnung+und+Foto_20_.jpg d-ÜBERBLICK über ...den LIDRAND Der Lidrand liegt an der Öffnung der Augenlider zur Lidspalte durch die das Licht in das Auge eintreten kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ea94ee37c5819161a23932/1483818740795/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28hier+hell+%2B+kontrastreich%29_NUR+UNTERES+DRITTEL+f%C3%BCr+BANNER.jpg d-ÜBERBLICK über ...den LIDRAND https://oscb-berlin.org/d-diagnosis daily 0.75 2020-11-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6240/1492867368677/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6253/1490283969495/ d-DIAGNOSE 1 Topographers provide a wide array of Tests and Investigations for the Ocular Surface and Tear Film and can thus not only assist in the Diagnosis of Dry Eye Disease but also in e.g. contact lens fitting by measuring the ocular surface Topography. The Oculus Topographer 5M is available with an advanced software package termed as´Dry Eye Report´from Jenvis, Jena Germany. This allows to fill in the complete Dry Eye Data Set including the questionnaire and ´digests´ the data into a graphic visualized report representation that allows even the novice in the field to perform a thorough and understandable Dry Eye Diagnosis. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6247/1490363640421/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6250/1489784237079/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6245/1491205688937/LINK-BILDCHEN_3+DIFFERENT+VITAL+STAINS.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010ddb29d6d9e70e623c/1530786317290/LINK-BILDCHEN+Tr%C3%A4nen+MENISCUS+Neu+4.JPG d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624b/1569332047373/LINK-BILDCHEN_LIPID+INTERFEROMETRIE.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6254/1544617168788/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_TEAR+FILM+LIPID+LAYER+%28TFLL%29+THICKNESS+Interferometry_BLINK+ANALYSIS%2C+TestScience+LIPIVIEW.png d-DIAGNOSE 1 Die Analyse des LIDSCHLAG-MUSTERS ist im Prinzip ein wichtiger Teil der Untersuchung der Funktion der Augenoberfläche - wird aber dennoch durch verfügbare Analysegeräte typischerweise nicht unterstützt. Blinzeln/ Lidschlag ist von enormer Bedeutung für die korrekte Bildung des Tränenfilms und seiner Lipidschicht, da selbst eine ausreichende Tränenmenge durch eine intakte Drüsenfunktion nicht ausreicht für einen intakten FILM von Tränen vor der Hornhaut, wenn der Lidschlag gestört ist und zu selten oder inkomplett erfolgt. Inkomplette Lidschläge lassen sich nur schwer manuell erfassen, vor allem wenn der Patient dies bemerkt. Wesentlich einfacher und zuverlässiger ist es, wenn eine Aufzeichnung des Lidschlagmusters automatisch zusammen mit der Nicht-Invasiven Untersuchung der Tränenfilm-Ölschicht und der Tränenfilm-aufbruchszeit (BUT) erfolgt, wie dies hier für das LipiVIEW Gerät (TearScience Inc.) gezeigt ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0dcc7893fc0b6e54097b1/1492181357346/OSCB-Bild_6_Dry+Eye+Disease_PATHOLOGY+in+DRY+EYE+DISEASE+...+Sequences+of+Secondary+Pathogenetic+Factors+lead+to+SURFACE+DAMAGE.png d-DIAGNOSE 1 Die entstehenden PRIMÄREN PATHOLOGIEN bestehen in MANGEL des TRÄNENFILMS sowie einer daraus typischerweise folgenden SCHÄDIGUNG des GEWEBES der AUGENOBERFLÄCHE. Beide Primären Pathologien werden regiert/ reguliert durch SEQUENZEN von SEKUNDÄREN PATHOGENETISCHEN FAKTOREN aus Faktoren, die jedem Kliniker geläufig sind https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010ddb29d6d9e70e623b/1492181368685/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+%28auf+gelbem+ZETTEL%29_NEU+2.png d-DIAGNOSE 1 Der DIAGNOSE-Prozess wird einfache, wenn man sich den grundlegenden Verlauf der Pathophysiologie/ Krankheitsentwicklung vor Augen führt. Dieser zeigt nämlich die Faktoren und Folgen. Grundlegende KAUSALE FAKTOREN sind ein MANGEL derTränen-SEKRETION sowie der Fähigkeit daraus einen Tränen-FILM zu formieren. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624d/1491205823431/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0e121c534a563178132d3/1492181536727/ d-DIAGNOSE 1 Auch die Primäre Pathologie des GEWEBESCHADENS der Augenoberfäche wird durch Sequenzen SEKUNDÄRER PATHOGENETISCHER FAKTOREN reguliert und verschlimmert. Bei einem Gewebeschaden tritt typischerweise eine entzündliche Reaktion ein als grundlegende Verteidingsstrategie jedes Gewebes. Wenn der Gewebeschaden chronisch wird, was beim Trockenen Auge oft der Fall ist, dann kann es zu einer CHRONISCHEN ENTZÜNDUNGSREAKTION kommen, die wiederum mächtige selbstverstärkende Regelkreise (Vicious Curcles - hier als drehende Pfeile dargestellt) der Gewebeschädigung in Gang setzen kann. Dies stellt den Übergang von der akuten Reizung zu einer Chronischen Entzündung dar und damit den Übergang von einem `Trockenen Auge´zur ´Erkrankung des Trockenen Auges´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010ddb29d6d9e70e623e/1530786850105/LINK-BILDCHEN_QUESTIONNAIRE+GANZ.GIF.png d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6243/1568462024307/LINK-BILDCHEN_NI-BUT_VITAL+Staining.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6248/1491205734163/LIPCOF-CONJUNCTIVAL-FOLDS d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624f/1491205797179/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010ddb29d6d9e70e623d/1530786584153/LINK-BILDCHEN_INCOMPLETE+BLINKS%2C+TearScience+LIPIVIEW_2.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6241/1492973507418/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0ff22f7e0abff4dcffadb/1492188993587/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Some+DIAGNOSTIC+TECHNIQUES+for+Dry+Eye+Disease.png d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6246/1491244559315/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624a/1492867390249/LINK-BILDCHEN_DIAGNOSTIC+EXPRESSION.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6252/1492247294055/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Estimation+of+TEAR+VOLUME%2C+Meniscus+HEIGHT%2C+Meniscus+CURVATURE+%282x+aus+Ophthalmologe%29_.png d-DIAGNOSE 1 Die HÖHE des Tränen-MENISKUS ist ein einfacher und nützlicher Indikator für die Tränenmenge auf dem Auge. Die ´Höhe´ist zwar nur scheinbar, weil die parabolische Kurve der Vorderfläche kein echtes Ende hat, aber das ist hinreichend genau. Mit zunehmender Tränenmenge nimmt auch die Höhe des Tränenmeniskus zu sowie die Größe desKreises, der am besten mit der vorderen Kurvatur des Meniskus übereinstimmt. Mit abnehmender Tränenmenge wird die Höhe des Meniskus und auch der Radius des Meniskus-Kreises kleiner. Eine abnehmende Tränenmenge führt typischerweise zu einem dünneren Tränenfilm, mit schlechterer Benetzung der Augenoberfläche, Erhöhten mechanischen Reibungskräften und punktuell erhöhter Konzentration der Salze in der Tränenflüssigkeit (Osmolarität) ... was alles zur Schädigung der Augenoberfläche führt und damit möglicherweise zur Erkrankung des Trockenen Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010ddb29d6d9e70e623f/1490462874764/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6244/1491244589348/LINK-BILDCHEN_Lid+Wiper+Epitheliopathy+%28LWE%29.JPG d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624c/1492973104405/LINK-BILDCHEN_TearLab+Abnahme.GIF d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0ff55bf629a9dbf618a5e/1530784636921/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6242/1492973452286/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e624e/1490458450261/ d-DIAGNOSE 1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee010edb29d6d9e70e6251/1491385973942/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_The+TEAR+MENISCUS+is+an+Indicator+for+Pre-Ocular+Tear+VOLUME_5.png d-DIAGNOSE 1 Der prä-okulare Tränen-FILM wird am unteren und am oberen Lidrand begrenzt durch einen verdickten Flüssigkeitsrand, der durch Oberflächenkräfte der Tränenflüssigkeit entsteht und Tränensee oder Tränen-MENISKUS genannt wird. Der Meniskus liegt auf der hinteren Lidkante und sein ´Boden´ ist die MARX´sche Linie, die wiederum die Oberfläche der Haut-Schleimhaut-Übergangszone (Engl.:MCJ) bildet. Die MCJ ist eine spezialisierte Epitheliale Übergangszone, in der sich die wässrig-feuchte Schleimhaut der Konjunktiva umwandelt in die ölig-trockene Epidermis der Haut, die hier beginnt und nach vorne weiter zieht. Im Querschnitt (linkes Bild) hat der Tränenmeniskus eine etwa dreieckige Form, wobei die Rückseite von der Hornhaut oder Bindehaut des Augapfels gebildet wird und die Vorderwand bildet eine parabolische Kurve. Die Füllung und daher das Volumen der Tränen im Meniskus korrespondiert mit den Tränen im Tränen-FILM. Die Füllung des Meniskus kann daher als Surrogat Parameter für Tränen im Tränenfilm verwendet werden. Daher gibt die Bestimmung der HÖHE des Meniskus einen guten Anhalt für die Tränenmenge - mit der Bestimmung der Kurvatur (als Radius des Meniskuskreises) lässt sich die Tränenmenge sehr genau bestimmen. (In der schematischen Zeichnung links ist die Dicke des Tränenfilms und der Ölschicht (gelb) auf seiner Oberfläche viel zu dick angeben relative zum Gewebe ... um den Tränenfilm überhaupt darstellen zu können.) https://oscb-berlin.org/d-overview-therapy-1-basics daily 0.75 2019-12-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac0/1491496680984/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac7/1576485647483/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0810ed2b857e333e5a703/1576485823952/LINK-BILDCHEN+%28Therapie%29_Inflammation+REHEARSAL.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36abc/1576485461189/LINK-BILDCHEN+%28Therapie%29_Tr%C3%A4nenersatz+W%C3%84SSRIG+3.png Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab5/1491310928701/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab3/1486827675035/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f07f1629687fbef7b49761/1492157555434/LINK-BILDCHEN+%28Therapie%29_Physical+Therapy%2C+IPL%2C+Intense+Pulsed+LightJPG.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0844c414fb5737111ffdb/1576485752337/LINK-BILDCHEN+%28Therapie%29_TETRACYCLINES.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab7/1491310948206/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36acc/1576485737593/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f08d0ed2b857e333e5e709/1492159780160/Some+THERAPEUTIC+APPROACHES+for+Dry+Eye+Disease.png Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36abe/1576485498522/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36aca/1576485709133/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab9/1490354855020/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f082d09de4bbfd3aac0220/1576485811450/LINK-BILDCHEN+%28Therapie%29_ANTI-Enz%C3%BCndliche+Therapie_Adhesions-Molek%C3%BCl-BLOCK+%28LIFITEGRAST%29.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab4/1486977721359/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f08b91b8a79b050d586b66/1492159381259/Stratified+Approach.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36abb/1576485448441/LINK-BILDCHEN+%28Therapie%29_Tear+Film+Deficiency+MANAGEMENT.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac8/1576485660575/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0b941be6594f0ff679ad4/1492171155048/%2Fd-overview-therapy-1-basics%2F%23d-Einige-THERAPIE-VORSCHL%C3%84GE-f%C3%BCr-das-TROCKENE-AUGE Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36abd/1576485473420/LINK-BILDCHEN+%28Therapie%29_Tr%C3%A4nenersatz+LIPID+2.png Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab6/1491310936604/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f08c48e58c6290e6fe2c45/1576485626062/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ad1/1576485770404/LINK-BILDCHEN+%28Therapie%29_AZITHROMYCIN.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac1/1576485557153/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f087a229687fbef7b4c4de/1576485590000/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f08dc2cd0f68deb2436307/1576485609006/LINK-BILDCHEN+%28Therapie%29_Minimizing+RISK+FACTORS+2+Bild.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36acb/1576485724598/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36ab8/1490354975808/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d0893fc0309af36abf/1491492710594/ Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f083b72e69cfd3f8c767cc/1576485794905/LINK-BILDCHEN+%28Therapie%29_CORTICOSTEROIDS.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac2/1576485571220/LINK-BILDCHEN+%28Therapie%29_ANTI-Inflammmatory+Drugs+-+Roter+Tropfen+2.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f0839a414fb5737111fc7c/1576485781887/LINK-BILDCHEN+%28Therapie%29_Lymphocytes+Activation+INHIBITORS.JPG Überblick THERAPIE 1 - BASIS-THERAPIE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58ee00d1893fc0309af36ac9/1576485674360/ Überblick THERAPIE 1 - BASIS-THERAPIE https://oscb-berlin.org/who-are-we daily 0.75 2019-05-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f4e834c534a5451bbf331c/1492445247261/Nadja+Knop+%28MD%2C+PhD%29.jpg Who are WE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58f4e78715d5db5e2530c771/1492445067775/Augenoberfl%C3%A4che%2C+FOTO+GESICHT+AUGE+und+NASE+%28aus+PASSFOTO+Erich+Knop+ca.+2010+ohne+Brille%29.png Who are WE https://oscb-berlin.org/d-diagnosis-2 daily 0.75 2020-11-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b37e4fcb57702bb447c/1490971225014/ d-Diagnose-2 TRÄNENBILDUNG DIAGNOSTISCHE EXPRESSION der Meibomdrüsen.Bei einem unauffällig aussehenden Lidrand (obere Abbildungen) ist nicht unmittelbar klar, ob die Meibomdrüsen wirklich aktiv sind. Aktiv bedeutet dabei, ob sie normales flüssiges klares Öl durch die Drüsenöffnung auf den hinteren Lidrand ausschütten können wenn ein leichter Druck auf sie ausgeübt wird wie er auch durch die Lidspannung bei einem normalen Lidschlag auftritt. Der Test auf die freie Durchgängigkeit der Drüsenöffnungen ist daher das Ziel der DIAGNOSTISCHEN EXPRESSION. Wenn milder Druck ausgeübt wird z.B. einfach mit dem Finger auf den äusseren Lidrand (mittlere Abbildung) oder mit einem speziellen standardisierten Instrument (Meibomdrüsen Evaluator, MGE TearScience Inc. - untere Abbildungen) dann wird eine normale Drüse klares Öl ausschütten, dass eine kleine Pfütze um die Drüsenöffnung herum bildet (Pfeil in mittlerer Abbildung). Eine inaktive Drüse dagegen schüttet kein Öl aus, was typischerweise an einer obstruktiven MDD liegt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b31e4fcb57702bb4420/1490957409173/ d-Diagnose-2 TRÄNENBILDUNG https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b34e4fcb57702bb4430/1490969263645/ d-Diagnose-2 TRÄNENBILDUNG Der originale Schirmer Test (SCHIRMER-1 Test) sammelt die Tränen, die während einer Zeit von 5 Minuten ohne Anästhesie gebildet werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b32e4fcb57702bb4428/1490968859920/ d-Diagnose-2 TRÄNENBILDUNG Die WÄSSRIGE SEKRETIONS-MENGE der Tränendrüsen wird durch den SCHIRMER Test gemessen. Dabei wird die wässrige Tränenflüssigkeit, die während einer Zeit von 5 Minuten gebildet wird, von einem Filterpapierstreifen, der über das temporale Drittel des Lidrandes hängt, aufgesaugt. Die Augenoberfläche und und die Tränendrüsen sind verbunden durch einen neuralen Reflexbogen für die Regulation der Sekretion. Er besteht aus den afferenten sensorischen (blaue unterbrochene Linie) und den efferenten Sekret-motorischen (grüne Linie) Nerven - zusammen mit dem Regulationszentrum im Hirnstamm mit dem efferenten oberen Speichelkern (dunkelgrün). Es gibt verschiedene Variationen des originalen Tests, die entweder mit einer zusätzlichen topischen Anästhesie oder, statt dessen, mit einer zusätzlichen nasalen Stimulation durchgeführt werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b36e4fcb57702bb4473/1490969836526/ d-Diagnose-2 TRÄNENBILDUNG SCHIRMER-2 Test: Der SCHIRMER-1 Test mit nasaler Stimulation ist eine Modifikation des einfachen Schirmer-1 Tests (ohne Anästhesie). Dabei wird die nasale Mukosa durch ein Baumwollstäbchen während der gesamten Dauer (5min) des Tests gereizt. Dieser Test ist nützlich, wenn der normale Schirmer-1 Test ein grenzwertig niedriges Ergebnis hatte. Der Schirmer-2 Test prüft die maximale Sekretionskapazität der wässrigen Tränendrüsen und die Ergebnisse dieses Tests zeigen die beste Korrelation mit einer Epithelschädigung bei Vitalfärbung mit dem Rose Bengal Farbstoff. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/58fa3b35e4fcb57702bb4438/1490969506423/ d-Diagnose-2 TRÄNENBILDUNG Wenn eine topische Tropfanästhesie der Augenoberfläche angewendet wird blockiert dies die Stimulierung der Tränensekretion, die durch die Reizwirkung des rauen Filterpapierstreifens ausgelöst wird. Dadurch wird mit dieser Variante des Schirmer Tests, die SCHÍRMER-1 Test MIT ANÄSTHESIE genannt wird, die sogenannte basale Sekretion geprüft. https://oscb-berlin.org/blink-on-dry-eye-disease-1 daily 0.75 2019-06-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c64b/1485192137009/ GLIMPSE on ... Dry Eye Disease According to Epidemiological Studies roughly about one in six or seven individuals suffers from symptoms of a manifest Dry Eye Disease. The number of individuals who have Meibomian Gland Dysfunction, including the a non-obvious form (NOMGD) without subjective symptoms, is respectively thought to be much higher. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c64d/1491824904171/ GLIMPSE on ... Dry Eye Disease Several Influence Factors promote Dry Eye Disease. This concerns a reduced level of male sex hormones (androgens) or an increased level of female sex hormones (Estrogens). Advance age and environmental factors that promote a desiccation of the ocular surface promote the risk for Dry Eye. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c650/1504294946459/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_TROCKENES+AUGE+W%C3%9CSTE+KAMELE+RETOUCHERT.jpg GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c64c/1485261938953/ GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59ad6e2712abd94ce64aa007/1504538163934/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a9b6dc4c0dbf2b30d90beb/1504294631394/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-DRY-EYE-DISEASE-%28Beispiel-FOTOS%29.gif GLIMPSE on ... Dry Eye Disease Some clinical images of patients with Dry Eye Disease - the disease severity increases from left to right including increasing alterations of the lid margin with pouting of Meibomian gland orifices, inflammation, lid margin rounding and irregularity, with loss of eye lashes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59c4d01b59cc686a11bf579a/1506070562045/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a68ce7a803bb089fc9ca90/1504087292386/OSCB-BILD_6_Dry+Eye+Disease_VICIOUS+CIRCLES+-+Schema+%2B+MAUI+2002_Folie48_25cm-72dpi.png GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c64f/1491828008490/ GLIMPSE on ... Dry Eye Disease ADVANCED AGE together with the health problems that tend to be associated with it, such as chronic diseases and several respective medications, some of which may negatively influence the function and health of the ocular surface, are is one of the main RISK FACTORS for Dry Eye Disease. ... please note - when we tend to become wise unluckily also the risk for Dry Eye Disease increases - whether the opposite is also true is unknown ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59074497d1758ec4d76d0587/59a9b48a579fb3b466392f74/1504294122979/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye_DIAGNOSIS-LINK-Bildchen.gif GLIMPSE on ... Dry Eye Disease - DIAGNOSIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59074497d1758ec4d76d0587/59a9b2b203596e26c0cc131f/1504293725970/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye_THERAPY%2C-LINK-Bildchen.gif GLIMPSE on ... Dry Eye Disease - THERAPY https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59074497d1758ec4d76d0587/590762b246c3c49694a7bab1/1493656300422/TROCKENES+AUGE%2C+DRY+EYE%2C+Pouting+der+Meibobmdr%C3%BCsen+am+Lidrand+auf+Eigenem+Auge+PSD_.jpg GLIMPSE on ... Dry Eye Disease - GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59074497d1758ec4d76d0587/5907483b1b631b48922c9cab/1493655027746/OSCB-GIF_ABSCHLUSS+VICIOUS+CIRCLES+%28aus+Dry+Eye+Concept%29_30-72_7-1_.gif GLIMPSE on ... Dry Eye Disease - NEW CONCEPT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59074497d1758ec4d76d0587/590747eb6b8f5b60839f4aca/1493649883913/How+to+UNDERSTAND+...+the+Ocular+Surface+and+DRY+EYE+DISEASE+%2B+Labnotes_17cm+300dpi.png GLIMPSE on ... Dry Eye Disease - OVERVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a9bb9f7131a5b734a3e18e/1504295854475/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_Meibomian-Gland-Dysfunction-%28MGD%29-with-irregular-and-obstructed-Orifices-inspissated-Oil-can-be-expressed-from-the-Glands.gif GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a9b70ae45a7c14983fc9af/1526916547788/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c64a/1485185359185/ GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a9bbf5893fc06716a0eede/1504295984217/ GLIMPSE on ... Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59073ff0b3db2ba7ea13c647/1485091365221/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_TROCKENES+AUGE+W%C3%9CSTE+KAMELE+RETOUCHERT.jpg GLIMPSE on ... 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TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599426fdb8a79b8271e48237/1502881543551/GIF-Animation-GRUNDLEGENDE-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE_DEUTSCH_Einzel-BILDER_400pix-32-2_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599476fbebbd1a972126da1a/1502902029112/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5995b80949fc2b77f9e634ff/1502984233768/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20852e/1502644706813/OSCB-Berlin.org_DRY+EYE_Meibomian+Gland+Dysfunction+%28MGD%29+-+CLINICAL+Images.png D-BLICK auf ... TROCKENES AUGE Eine STÖRUNG der MEIBOMDRÜSEN, die MeibomDrüsen Dysfuktion (MDD) ist die häufigste primäre Ursache für die Entwicklung eines Trockenen Auges. Dies ist typischerweise eine Drüsenverstopfung mit eingedicktem Sekret. Sie führt zu einem Mangel von Meibomöl auf dem Tränenfilm und damit zu erhöhter Verdunstung der wässrigen Tränen und einem nachfolgenden Trockenen Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6d6bbaf9d520b7a487dfd/1604435230860/OSCB-Berlin.org_SYMPTOME-des-Trockenen-Auges_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE - Symptome https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6d713af9d520b7a488386/1604435223511/OSCB-Berlin.org_TR%C3%84NENFILM-MANGEL-2_LINK-Bildchen_.gif D-BLICK auf ... TROCKENES AUGE - Tränenfilm-Mangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6d9cae8290d7830d16724/1573313011996/OSCB-Berlin.org_Grundlegende-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE-sind-ein-MANGEL-von-Tr%C3%A4nen-PRODUKTION-und-von-Tr%C3%A4nen-FILM-BILDUNG---EINFACH--NEU_WEB_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6d8b794d2ca4234a9c009/1604435236687/OSCB-Berlin.org_GEWEBE-SCHADEN_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE - Gewebe-Schaden https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6da66e8290d7830d1708b/1573313198891/OSCB-Berlin.org_RISIKO-FAKTOREN_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5dc6d6b909cdf43d6dabbd04/5dc6da0b492ddd0f8b7d6957/1573313197259/OSCB-Berlin.org_ST%C3%96RUNG-der-REGULATIONSSYSTEME_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de2084ff/1498408836735/ D-BLICK auf ... TROCKENES AUGE Wichtige SYMPTOME von Patienten mit der Erkrankung des TROCKENEN AUGES sind z.B. eine schwankende Sehschärfe durch Schwankungen der Tränenfilmqualität sowie Trockenheitsgefühl, und Augenreizung bis zu Schmerzsyndromen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f98721bafe6b4792a061482/1603826227022/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_20-11-0%2C2_.gif D-BLICK auf ... TROCKENES AUGE Auswärtsrollung des Lidrandes (ENTROPIUM) durch Erschlaffung des Bindegewebes ist eine typische Altersveränderung, die einen kompletten Lidschluss verhindert und daher zur Augentrockenheit führt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208524/1502792909239/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599443dcf14aa10e7f8ecd2b/1604434917727/OSCB-Berlin.org_TR%C3%84NENFILM-MANGEL-wird-verschlimmert-durch-ein-Netzwerk-von-SEKUND%C3%84REN-Pathogenetischen-Faktoren.gif D-BLICK auf ... TROCKENES AUGE Die Nachfolgenden/ Sekundären Faktoren beim Tränenfilm-Mangel bilden Kaskaden der zunehmenden Störung (kleine weisse Pfeilie mit rotem Rand). Allerdings beeinflussen Sie sich auch gegenseitig und bilden Netzwerke (angedeutet durch einen grösseren horizontalen weissen Pfeil). Daher ist es schwierig, diese sekundären Störungen klar nur einer der verschiedenen wässrigen oder Lipid-Störung des Tränenfilms zuzuordnen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20851c/1502808917233/OSCB-Berlin.org_Erh%C3%B6hte-mechanische-REIBUNG-verursacht-eine-Gewebe-Sch%C3%A4digung-3D.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599400da197aeacc911a54fc/1502871787720/OSCB-GIF_aus+2x+BILD_3.1.0_Ocular+Surface_FUNCTIONAL+UNIT+%2B+TR%C3%84NENFLUSS+auf+Dry+Eye+CONCEPT+Layout_F%C3%9CR+GIF+1%2B2v2_18cm-72dpi_2-1fps_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f40dd3b09e9764cd3c0cd9f/1598086469453/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a58252cf81e07eb2c6142c/1504019028602/OSCB-Berlin.org_ST%C3%96RUNG-der-REGULATIONSSYSTEME_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE Unterliegende STÖRUNG DER REGULATORISCHEN SYSTEME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599599816a4963f73735fb68/1603829318136/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f41356fa662a571342e5abe/1598109057670/OSCB-Berlin.org+%28c%29+ENK_6_Risiko-Faktoren+f%C3%BCr+Trockenes+Auge+-+ALTER_20_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994159d197aeacc911b0472/1502877094828/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208528/1544986865107/ D-BLICK auf ... TROCKENES AUGE Wenn die REGULATIONSSYSTEME der Augenoberfläche GESTÖRT SIND dann kann es zu Funktionsstörungen kommen, die die grundlegenden Funktionskomplexe für die Feuchterhaltung der Augenoberfläche schädigen ... und daher zu der prototypischen Erkrankung führen, die immer dann eintreten kann, wenn die Befeuchtung gestört ist ... das TROCKENE AUGE. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7687265720f25bf4ad8d91/1568048944852/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM_NUR-BLINZELN-9-19_500-16-1_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59973839e45a7c94a2edc7d3/1558370561302/OSCB-Berlin.org_GIF-Animation_Typische-SYMTOME-beim-Trockenen-Auge_Bild-1-4v4_30-72_6-x2sec-PSE_WEB_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a540566f4ca3e279489784/1604435168866/OSCB-Berlin.org_SYMPTOME-des-Trockenen-Auges_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE BESCHWERDEN & BEFUNDE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208530/1502643487628/ D-BLICK auf ... TROCKENES AUGE Die Meibomdrüsen Dysfunktion (MDD) einzelner Drüsen kann auch ohne subjektive Symptome des Patienten ablaufen, da durch die grosse Zahl der Meibomdrüsen in den Augenlidern ein Überschuss an Öl besteht und so zuerst keine Beschwerden auftreten. Dies Form der MDD nennt man Nicht-Offensichtliche MDD (NOMDD). Diese Störung ist vermutlich weit verbreitet und die ´normale´sichtbare und symptomatische MDD ist vermutlich nur die Spitze des Eisberges der wirklichen Drüsenerkrankung. NOMDD wird ohne genaue Diagnostik erst entdeckt, wenn so viele Drüsen erkrankt sind, dass es zu einem absoluten Mangel an Öl und dann zu einem instabilen Tränenfilm kommt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a58239d482e90144f24104/1504019017180/OSCB-Berlin.org_Grundlegende-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE-sind-ein-MANGEL-von-Tr%C3%A4nen-PRODUKTION-und-von-Tr%C3%A4nen-FILM-BILDUNG---EINFACH--NEU_WEB_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE HAUPT-URSACHEN/ Grundlegende KAUSALE FAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f4136aba662a571342e7691/1598109370702/OSCB-Berlin.org+%28c%29+ENK_Risiko-Faktoren+f%C3%BCr+Trockenes+Auge+-+CHRONISCHE+KRANKHEIT_20_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a582694c0dbf78d3ddda10/1504022520592/OSCB-Berlin.org_RISIKO-FAKTOREN_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE Innere und Äussere RISIKO-FAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20852a/1498409662153/ D-BLICK auf ... TROCKENES AUGE Verschiedene RISIKOFAKTOREN begünstigen das Auftreten eines Trockenen Auges. Dazu zählen neben erhöhten Lebensalter sowie vermindertem Spiegel männlicher Geschlechtshormone (Androgene) und erhöhtem Spiegel weiblicher Geschlechtshormone - ebenso chronische Erkrankungen und chronische Medikation, wie auch Mangel an bestimmten Nährstoffen (z.B. Omega-6-Fette) und ungenügende Trinkmenge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20852c/1502464499863/ D-BLICK auf ... TROCKENES AUGE Äussere RISIKOFAKTOREN in der Umwelt bestehen vor allem in Faktoren, die die Austrocknung des Auges begünstigen. Dies kann geschehen entweder indem die Verdunstung direkt erhöht wird, wie hohe Temperaturen, trockene Klilmaanlagenluft und Wind oder indem Sie die Verdunstung indirekt erhöhen durch verminderten Lidschlag und damit verminderte Freisetzung von Meibomöl und seltenere Erneuerung des Tränenfilms. Kontaktlinsentragen kann ebenfalls die Verdunstung erhöhen und Kontaklinsen haben generell höhere Ansprüche an die Tränenmenge und Qualität so daß beim Linsentragen ein sonst gerade noch ausreichender Tränenfilm problematisch werden kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208516/1502722952881/GIF+BASALER+Vicious+Circle+ohne+Entz%C3%BCndung+Tr%C3%A4nenfilm-Mangel+%2B+Oberfl%C3%A4chenst%C3%B6rung%2C+Neu+auf+Zettel_ENGLISCH+2v2_26-72_%2B+OHNE+Legende_2-1fps_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f413bda09e9764cd3c754a7/1598110717563/OSCB-Berlin.org+%28c%29+ENK_Risiko-Faktoren+f%C3%BCr+Trockenes+Auge+-+MEDIKAMENTE_10_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59973a958419c28daaaa9bfa/1558370549904/OSCB-Berlin.org_%C3%84USSERE-RISIKO-FAKTOREN-in-der-UMWELT-st%C3%B6ren-Feuchtigkeit-%26-Gesundheit-der-Oberfl%C3%A4che-u-k%C3%B6nnen--Trockenes-Auge-ausl%C3%B6sen_WEB_%2BRauch.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994776dbe6594d1f3e2eb6f/1502902152863/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208520/1598089464133/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208501/1498408765239/ D-BLICK auf ... TROCKENES AUGE Nach Epidemiologischen Studien zur Krankheitshäufigkeit leiden etwa ein Sechstel der Bevölkerung unter Symptomen eines Trockenen Auges. Die Häufigkeit einer Funktionsstörung der Meibomdrüsen, welche nach neueren Erkenntnissen, die häufigste Ursache eines Trockenen Auges darstellt, ist noch wesentlich höher. Bei Vielen läuft die Meibomdrüsen-Dysfunktion (MDD), unbemerkt ab, da sie noch keine Symptome verursacht - dies wird bezeichnet als ´Unauffällige /Verborgene MDD´ (Engl.: ´Non-Obviouus´MGD oder NOMGD). Diese ist noch weit häufiger und kann bereits zu einer unbemerkten Schädigung der Drüsen innerhalb der Augenlider führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208503/1502558242223/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208511/1604228739321/ D-BLICK auf ... TROCKENES AUGE Eine andere Form der LID- und BLINZEL-STÖRUNG ist die Einwärtswendung des Lidrandes (Entropium), die ebenfalls einen vollständigen Lidschluss erschwert und gleichzeitig zu einem Wimpernreiben (Trichiasis) führt mit meist starker Reizung der Augenoberfläche auf dem Augapfel. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a5407849fc2b0fce315488/1604481388631/OSCB-Berlin.org_TR%C3%84NENFILM-MANGEL-2_LINK-Bildchen_.gif D-BLICK auf ... TROCKENES AUGE GRUNDLEGENDE (Primäre) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994185615d5db0803cacf5b/1502877792819/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20850b/1502560175531/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208513/1502720118796/ D-BLICK auf ... TROCKENES AUGE Ein schematische Animation erklärt, wie ein TRÄNENFILM-MANGEL eine OBERFLÄCHEN-SCHÄDIGUNG des Auges auslöst und so zum Vollbild des Trockenen Auges führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f7d87696b8eab75a42e7922/1602062242173/OSCB-Berlin.org_+%28c%29+ENK%2C+GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_600pix-11-2_NEU_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208522/1502784822148/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599699482994ca7022783899/1503041882517/GIF-Animation-GRUNDLEGENDE-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE_DEUTSCH---Focus-PLATTENEPITHEL-METAPLASIE_VOLLpix-26-1%2C5.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208534/1502645695383/ D-BLICK auf ... TROCKENES AUGE HÖHERES LEBENSALTER zusammen mit dort zunehmend auftretenden gesundheitlichen Problemen wie Chronische Erkrankungen und auch chronische Einnahme mehrerer Medikamente, von denen einige die Funktion der Augneoberfläche negativ beeinflussen können, ist ein Hauptrisikofaktor für die Erkrankung des Trockenen Auges. ... ein Trost mag sein - Wenn man weise wird dann nimmt leider auch das Risiko für ein Trockenes Auge zu- ob auch das Gegenteil zutrifft ist nicht bekannt ;-) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59973b52f14aa1ab06cbaa3b/1503083369207/OSCB-Berlin.org_Einige-THERAPIE-Optionen--bei--Meibomdr%C3%BCsen-Dysfunktion-%28MDD%29_Lipid-Substitution-%2B-Physikalische-Therapie.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de20850d/1502475544214/ D-BLICK auf ... TROCKENES AUGE Die beiden grundlegenden Ursachen für die Entwicklung eines Trockenen Auges sind Störungen der DRÜSEN-Funktion und/oder Störungen der LID- und LIDSCHLAG-Funktion. Dies führt zu Störungen der PRODUKTION (Sekretion) von Komponenten der Tränen und/oder Störungen der BILDUNG (Formation) des Tränen-FILMS. Allein oder gemeinsam führt dies zu einem MANGEL in der FORMATION und Stabilität des TRÄNENFILMS, der dann die Augenoberfläche in der Lidspalte nicht mehr hinreichend feucht halten kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994150ae4fcb5624a67a512/1502876945944/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994243137c5815907f64572/1502880844701/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208507/1502557366430/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f413a47a354d12015622503/1598110293161/OSCB-Berlin.org+%28c%29+ENK_Risiko-Faktoren+f%C3%BCr+Trockenes+Auge+-+HORMONE_10_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208532/1491928826827/ D-BLICK auf ... TROCKENES AUGE SELBSTVERSTÄRKENDE REGELKREISE der Krankheitsverschlimmerung (angedeutet durch sich drehende Kreise) verschlimmern die in der Mitte dargestellten krankhaften Veränderungnen von TRÄNENMANGEL (Mitte oben) und GEWEBEZERSTÖRUNG (Mitte unten) - ALLE DETAILS dazu finden Sie beim NEUEN HOLISTISCH DYNAMISCHEN KONZEPT für das TROCKENE AUGE. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59941ab8197aeacc911b31ea/1502878441190/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599415fe893fc0f61689051f/1502877199810/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599477216a4963aaeeeb7d36/1502902060117/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d768b611c762030098409e6/1568050031412/OSCB-Berlin.org_Die+wichtigsten+Faktoren+in+der+Tr%C3%A4nenfilmst%C3%B6rung+die+das-Oberfl%C3%A4chengewebe+sch%C3%A4digen+beim+Trockenen+Auge+sind+Chronisch+MECHANISCHE+REIBUNG+und+HYPER+OSMOLARIT%C3%84T_20_ALS+JPG_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208526/1502795159524/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59a5409c8fd4d2ef9cb0ac68/1604435074985/OSCB-Berlin.org_GEWEBE-SCHADEN_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE SCHÄDEN (Pathologien) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208505/1502473408185/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-2x-3D-%C3%96L_NEU-HH%2BIRIS-3D-%2BHH-WEISS-WEB.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5996a6f7db29d612b1164518/1503045384167/OSCB-Berlin.org_Lidrand-Parallele-Conjunctivale-FALTEN-%28LIPCOF%29-der-Bindehaut-treten-auf-durch-Besch%C3%A4digung-des-Bindegewebes-bei-Chronischem-Trockenen-Auge.gif D-BLICK auf ... TROCKENES AUGE Durch die chronische Entzündungsreaktion beim Trockenen Auge wird die normale Struktur des Bindgewebes (hellgrüner Bereich unter der rosa markierten Epithelschicht) stark aufgelockert. Die langen Kollagenfaserbündel werden zerschnitten durch Protein-auflösende Enzyme (Proteasen) und viele Entzündungszellen (hier rot markiert) kommen im Gewebe vor und lockern es weiter. Dadurch wird die dann sehr lockere Bindehaut durch den Lidrand beim normalen Lidschlag in sichtbaren Falten aufgeschoben. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa1b6d239a10f3d57d6325a/1604433635486/OSCB-Berlin.org_RISIKO-FAKTOREN_LINK-Bildchen.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208536/1491929155322/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_TROCKENES+AUGE+W%C3%9CSTE+KAMELE+RETOUCHERT.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208509/1502635499867/ D-BLICK auf ... TROCKENES AUGE Ein INSTABILER TRÄNENFILM ist die Hauptursache für die Entstehung eines Trockenen Auges. Im diesem schematischen Beispiel bleibt der (hier blaue) Tränenfilm nur für etwa 2 Sekunden stabil bevor er aufbricht und verschwindet ... wodurch die Augenoberfläche dann trocken wird ... zumindest stellenweise. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5995b61a17bffc70664dc8a6/1598089455398/ D-BLICK auf ... TROCKENES AUGE Schematische grafische Darstellung der Entzündungsreaktionen beim Trockenen Auge aus einer eigenen Arbeit in ´The Ocular Surface, 2005´. Die Reaktionen entsprechen denen die im nebenstehenden Text näher erläutert sind. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f86cfc89ec4b03a7a38a69c/1602670955536/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2C%2BSQUAMOUS%2BMETAPLASIA_Trockenes%2BAuge%2C%2BPLATTENEPITHEL%2BMETAPLASIE%2B%28LM%2BSEM%29_20_.jpg D-BLICK auf ... TROCKENES AUGE Oberflächenschaden mit vermehrter Zellabschilferung und Verlust von schleimbildenden Becherzellen , (hier Plattenepithelmetaplasie durch Kontaktlinsentragen). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5995c45937c581af1f6e45ad/1502987385707/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de208518/1502726349854/ D-BLICK auf ... TROCKENES AUGE Der Tränenfilm und die Augenoberfläche beeinflussen sich gegenseitig und sind in ihrer Gesundheit und Intaktheit sogar voneinander abhängig - wie die vorherige Animation illustriert. Bei den Fällen von Trockenem Auge, die hierzulande typischerweise auftreten, besteht allerdings meist (grosse Pfeilspitze) zuerst eine Tränenfilmstörung, die dann erst die Gewebeoberfläche schädigt. Deutlich seltener (kleinePfeilspitze) führt eine vorherige Oberflächenschädigung zu einer Tränenfilmstörung. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/599471a31e5b6c92fe66ddb9/1502900670026/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59944676ff7c50aff7704559/1502889594164/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f987c883e9996655c6fec83/1603829338560/OSCB-Bild_6.0_Dry+Eye+Disease_Tear+Film+Deficiency+TR%C3%84NENFILM+MANGEL+-+Potential+MIXTURE+of+individual+Types+into+MIXED+TYPE_.jpg D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59948b9e2994ca66a56bcc8b/1502907316437/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5994079aebbd1a8e77e0b2e5/1502873514073/ D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c1106394ae23730c6d2ab69/1544619609689/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_.gif D-BLICK auf ... TROCKENES AUGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de2084fd/1491928625805/ D-BLICK auf ... TROCKENES AUGE Einige KLINISCHE BILDER von Patienten mit der Erkrankung des Trockenen Auges - die Schwere der Erkrankung steigt hier von links nach rechts an und ist erkennbar an zunehmenden Veränderungen des Lidrandes mit Verstopfung der Meibomdrüsen-Öffnungen, entzündlichen Veränderungen, Sekret-Ansammlungen, Abrundung und Unregelmäßigkeit des Lidrandes und eines Verlustes von Wimpern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5993f404db29d634de2084f9/1485091365221/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_TROCKENES+AUGE+W%C3%9CSTE+KAMELE+RETOUCHERT.jpg D-BLICK auf ... TROCKENES AUGE https://oscb-berlin.org/orthokeratology-contact-lenses daily 0.75 2019-08-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b277e26f4ca36cb5e54e73/1504868339721/OSCB-Berlin.org_EFFECT-of-ORTHOKERATOLOGY-Contact-Lenses-on-Refraction-%28in-a-MYOPIC-Patient%29.gif Orthokeratology Contact Lenses The effect of correction of the outer corneal shape by an Orthokeratology (OK) Contact Lens is shown here for a myopic patient. The flattening of the corneal surface (lower image) leads to de-focusing of the light and the focus point in the eye is therefore shifted to the back onto the retina. This leads to a sharp image in contrast to the uncorrected situation (upper image) where the focus point is in front of the retina which results in an unfocused image ... as every myopic patient knows ;-) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b93334cf81e006d591db3f/1505309502003/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Anatomy-and-Histology-of-The-Human-CORNEA+%28Spot0965%29---Epithelium%2C-Basement-Membrane%2C-BOWMAN%C2%B4s-Layer_HISTOLOGY-%2B-SCHEMA-ZEICHNUNG_WEB-30_.gif Orthokeratology Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bee4c449fc2ba7e2726fdf/1505682701299/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif Orthokeratology Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59bee461cf81e0eca2c26c78/1505682544717/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif Orthokeratology Contact Lenses https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59b277048dd04187fcd456a0/1504868115644/OSCB-Berlin.org_Temporary-Re-shaping-of-the-Cornea-by-Orthokeratology-Contact-Lenses---RE-Normalization_.gif Orthokeratology Contact Lenses A simplified schematic drawing illustrates the effect of ORTHOKERATOLOGY-CONTACT LENSES on the shape of the Corneal Epithelium. (The size of the corneal epithelium in the drawing is largely exaggerated for didactic reasons) https://oscb-berlin.org/alt-f-0-home daily 0.75 2018-08-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b35372baa4a99232a49e603/1530214217791/Dominique+BREMOND+GIGNAC_s200_PSD-OPT_7-72_.jpg F-0-HOME Dominique BREMOND, Paris https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f4a5780d9297f9ed511ab0/1509197711344/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif F-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f4aa11652dea268785b97c/1527771010693/Serge+DOAN+%28La+Fondation+Ophtalmologique+Adolphe+de+Rothschild%2C+Paris%29_PSD-OPT_7-72_.jpg F-0-HOME Serge DOANE, Paris 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https://oscb-berlin.org/es-0-home daily 0.75 2018-09-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb5708/1519563814405/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - Los SISTEMAS DE MANTENIMIENTO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb570c/1519563807371/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - La CIUDAD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb570a/1519558324898/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - El CONCEPTO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb570e/1519563795951/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - La MISIÒN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb5710/1519558298884/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - La INSTITUCIÓN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/59f624e171c10b247deb5705/59f624e171c10b247deb5706/1519559909330/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ES-0-HOME - Los TEMAS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f624e171c10b247deb5721/1509200974097/ ES-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/59f624e171c10b247deb5717/1509126019907/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif ES-0-HOME Lentes de contacto 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The START https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4a97958165f54918e630aa/1509126019897/GIF+FUNCTIONAL+UNIT+7+...+OHNE+Text+%2B+L%C3%84NGERE+%C3%9CBERg%C3%A4nge+%2B+BLINZELN+NEU+%2B+OSCB+VERSCHOBEN_TR%C3%84NEN+3x+LANGSAMER_99-5fps_UNT+WEG+f%C3%BCr+BANNER.gif Turk-0-HOME https://oscb-berlin.org/pol-1-start daily 0.75 2018-03-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24671/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24655/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24663/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif POL-1-Start 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24651/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg POL-1-Start ... i ZESPÓŁ ‘SUCHEGO OKA’ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2469b/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2466d/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b246a3/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2464d/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2464f/1512819831601/OSCB-Berlin.org_THE-OCULAR-SURFACE--%26--TEAR-FILM_%28quer-%2B-frontal-mit-BESCHRIFTUNG%29_WEB.gif POL-1-Start POWIERZCHNIĘ OKA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2465b/1512819831611/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24677/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24669/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2468f/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POL-1-Start Ten schematyczny animowany diagram ilustruje zasadniczą funkcję powieki w rozprowadzaniu łez - faktyczne krople łez pojawiają się w szparze powiekowej tylko podczas zwiększonego wydzielania . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24689/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif POL-1-Start Stały Przepływ Łez na Powierzchni Oka (1) z miejsca ich głównej produkcji w gruczole łzowym poprzez (2) dobrze widoczną rogówkę i spojówkę, które muszą być stale nawilżone, po (3) system dróg łzowych odprowadzających łzy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24687/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2469f/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2468b/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24695/1519917008074/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif POL-1-Start Umiarkowane SUCHE OKO zazwyczaj objawia się tylko łagodnym zaczerwienienie spojówek i brzegów powiek, które jest wywołane przez stan zapalny, opisywany terminem´ "Keratoconjunctivitis Sicca" . Ujścia łojowych gruczołów Meiboma są często zablokowane przez widoczną lub niewidoczną zagęszczoną wydzielinę (co stanowi najczęstszą pierwotną przyczynę Zespołu Suchego Oka). Objętość łez jest obniżona, a nabłonek Powierzchni Oka ma wiele drobnych ubytków, które wybarwiają się przy barwieniu fluoresceiną. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2467f/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif POL-1-Start Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24673/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a97fa8c0d9297988859a3e1/1519909532289/The+CONCEPT+...+BANNER_2500pix_Quadratisch+52x52cm_2+RE-ARRANGIERT_NUR+2+Augen+OHNE+Bildchen.jpg POL-1-Start - . . . sprawia, że wszystko można łatwiej zrozumiećWrite here… https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2469d/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2466f/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24665/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24653/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b2467d/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif POL-1-Start ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24699/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24657/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24681/1512819831644/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif POL-1-Start The fine structure of the surface epithelium may undergo a deterioration where it is exposed to influence by a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24649/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif POL-1-Start https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a4f54adf9619a5160b24683/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif POL-1-Start Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. 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The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. 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Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f6d4f9619ab0c3589762/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif Copy of E-1-START https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f6d4f9619ab0c35897a6/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif Copy of E-1-START https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f6d4f9619ab0c3589784/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif Copy of E-1-START https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f6d4f9619ab0c3589786/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif Copy of E-1-START ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://oscb-berlin.org/english-0-home-for-translation-in-japanese daily 0.75 2018-01-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f7e371c10be1387da868/1509126019905/ GOOGLE TRANSLATE für JAPANESE_Copy of English-0-HOME Tränen und Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f7e371c10be1387da885/1509126019931/GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+2_30-2fps_.gif GOOGLE TRANSLATE für JAPANESE_Copy of English-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f7e371c10be1387da877/1509200962447/IMPROVE+YOUR+TEACHING_Folie6_.JPG GOOGLE TRANSLATE für JAPANESE_Copy of English-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5a58f7e371c10be1387da86e/1509126019911/ GOOGLE TRANSLATE für 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2c0/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2b2/1512819831615/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5af80933758d46b9d4221b79/1526204732267/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2ba/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2a2/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2ac/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2b8/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif ALT_ES-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8cec8a922d433deaa2be/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif ALT_ES-1-START2 https://oscb-berlin.org/alt-es-1-start4 daily 0.75 2018-07-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a83b/1512819831670/ ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a82d/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a843/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a82b/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a83d/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a841/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a81f/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a831/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a825/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5af809606d2a736d3c88c9dc/1526204776100/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a837/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a821/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a82f/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a835/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif ALT_ES-1-START4 A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that indiates an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low and the tissue of the Ocular Surface epithelium has many small defects, that occurs as small spots in vital staining with a blue stain (fluorescein). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a839/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a827/1512819831654/The-Tear-FILM-%26-The-OCULAR-SURFACE__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a829/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ALT_ES-1-START4 This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a81a/1524404438580/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ALT_ES-1-START4 - HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a814/1524404428405/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg ALT_ES-1-START4 - PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a816/1524404414849/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif ALT_ES-1-START4 - Typical SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a818/1524404403301/OSCB-Bild_6.0_Dry+Eye+Disease_Typical+Symptoms+in+Dry+Eye+Disease+UNstable+or+Blurred+VISION%2C+IRRITATION%2C+PAIN_10cm.jpg ALT_ES-1-START4 - Typical SYMPTOMS in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a812/1524404391872/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__LIPID+DEFICIENCY+induces+Tear+Film+Deficiency+and+Surface+Damage.gif ALT_ES-1-START4 - Details on Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5adc8d8a70a6ad0a2885a811/5adc8d8a70a6ad0a2885a81c/1524404382215/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ALT_ES-1-START4 - The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a823/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ALT_ES-1-START4 El recambio continuo de lágrimas en la superficie ocular va (1) de su producción principal en la glándula lagrimal sobre (2) la córnea y la conjuntiva fácilmente visibles y que deben bañarse constantemente (3) hacia el sistema de drenaje lagrimal que drena las lágrimas hacia la nariz. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a833/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a845/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png ALT_ES-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc8d8a70a6ad0a2885a83f/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ALT_ES-1-START4 https://oscb-berlin.org/alt-f-1-start1 daily 0.75 2018-04-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32df5/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32dff/1524404908149/ARZT-Symbol+%28GR%C3%9CN%29_%C3%9Cberarbeitet+3R+KLEIN.png F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32dfd/1524404925344/Patient+Mann%26Frau%2C+Layman_Symbolbild_3+KLEIN.png F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ae5a567562fa7d975a8cdb6/1524999536593/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32df7/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32dfb/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32df9/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif F-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5adc9109352f538288f32e01/1524404889769/SMILEY+Clever%2C+Genie%2C+Brille+ENK_%C3%9Cberarbeitet_Symbolbild+3+KLEIN.png F-1-START1 https://oscb-berlin.org/alt-es-1-start3 daily 0.75 2018-06-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f715d/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif ALT_ES-1-START3 Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4c5670a6ad6e396fc984/1525632149867/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Kontaktlinen+als+MEDIZINISCHES+WERKZEUG_GANZ+OHNE+Text_jpg6+20_.jpg ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7153/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f7141/1525631826610/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg ALT_ES-1-START3 - CONTACT LENSES & Ocular Surface https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f713f/1525631849748/OSCB-Bild_6.0_Dry+Eye+Disease_Typical+Symptoms+in+Dry+Eye+Disease+UNstable+or+Blurred+VISION%2C+IRRITATION%2C+PAIN_10.jpg ALT_ES-1-START3 - MAIN SYMPTOMS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f713d/1525631881786/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png ALT_ES-1-START3 - MAIN CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f7139/1525631865251/OSCB-Bild_6.0_Dry+Eye+Disease_Some+Important+RISK+FACTORS+%2B+WAGE.png ALT_ES-1-START3 - Important RISK FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f713b/1525631797852/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif ALT_ES-1-START3 - CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef49d770a6ad6e396f7136/5aef49d770a6ad6e396f7137/1525631837410/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png ALT_ES-1-START3 - BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f715b/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif ALT_ES-1-START3 ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f714e/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7161/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7144/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7155/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7165/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif ALT_ES-1-START3 Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7134/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7157/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7151/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f714a/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7148/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7167/1525631670250/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7159/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif ALT_ES-1-START3 Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f715f/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif ALT_ES-1-START3 The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7146/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f714c/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif ALT_ES-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef49d770a6ad6e396f7163/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif ALT_ES-1-START3 https://oscb-berlin.org/alt-ital-1-start1 daily 0.75 2018-06-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b0b/1512819831598/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_DRY-EYE-DISEASE-can-be-TRICKY-Condition.gif ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b07/1512819831594/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Word-field-DRY-EYE.gif ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b03/1525631073646/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b0f/1525633027593/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b09/1512819831596/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Doctor-my-eyes-are-WATERY-...-can-that-be-a-Dry-Eye.gif ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b11/1525633098009/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b0d/1525633049934/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg ITAL-1-START1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4ddc1ae6cf3823bd3b05/1512819831591/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITAL-1-START1 https://oscb-berlin.org/alt-ital-1-start2 daily 0.75 2018-06-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3feaa5/1526663447246/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM+ohne+Text_LINK+Bildchen_.jpg ITAL-1-START2 - Il FILM LACRIMALE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3feaa1/1526663776024/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Physical+Therapy_10_2.jpg ITAL-1-START2 - TERAPIA delle PALPEBRE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3fea9c/1526663418496/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg ITAL-1-START2 - La SUPERFICIE OCULARE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3feaa3/1526663691554/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN.jpg ITAL-1-START2 - Alcune OPZIONI di TERAPIA https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3fea9a/1526663534591/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg ITAL-1-START2 - Malattia dell'OCCHIO SECCO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e1b0e2e7248fe3fea99/5aef4e1b0e2e7248fe3fea9f/1526663597110/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg ITAL-1-START2 - LENTI A CONTATTO 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feab4/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feaba/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feacc/1525633229244/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feac6/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feac0/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feaaa/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3fea96/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feac8/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b01d25d1ae6cf341dd4deea/1526846055116/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feac2/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feabe/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aff0b74aa4a99a3335e9b89/1526668145876/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_20_%2Cjpg.jpg ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feaac/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ITAL-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e1b0e2e7248fe3feab2/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif ITAL-1-START2 https://oscb-berlin.org/alt-ital-1-start3 daily 0.75 2018-06-09 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7525/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7542/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5b0010e103ce6487dbc543e4/1526731033288/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Typische+SYMPTOME+des+Trockenen+AUGES_LINK+BILDCHEN_LINK+BILDCHEN_START3_.jpg ITAL-1-START3 - SINTOMI Principali https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5b001068352f534e97ec5161/1526730903918/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_GANZ+OHNE+Text_jpg6_10+LINK+Bildchen_START3_.jpg ITAL-1-START3 - FATTORI DI RISCHIO Importanti https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5aef4e84aa4a9960d83b7522/1526730619134/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__KONTAKTLINSE+auf+der+AUGENOBERFL%C3%84CHE_10+LINK+Bildchen_.jpg ITAL-1-START3 - LENTI A CONTATTO e Superficie Oculare https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5aef4e84aa4a9960d83b751e/1526730647201/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_10.png ITAL-1-START3 - SEGNI CLINICI Principali https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5aef4e84aa4a9960d83b751c/1526730454020/OSCB-Berlin..org_Basic-CAUSATIVE-FACTORS_DEFICIENCY-in-TEAR-Production-and-FILM-Formation%2C-GANZ-EINFACH_LINK-Bildchen.gif ITAL-1-START3 - FATTORI CAUSATIVI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4e84aa4a9960d83b7517/5aef4e84aa4a9960d83b7518/1526730632871/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png ITAL-1-START3 - FUNZIONE di Base https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7548/1525631194955/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7546/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif ITAL-1-START3 L'igiene insufficiente è un fattore cruciale nell'usura delle lenti a contatto e determina un più alto tasso di infezioni oculari nei portatori di lenti a contatto. I microbi possono essere introdotti dalle dita di chi li indossa o dall'uso dell'acqua del rubinetto, che dovrebbe essere omessa. Alcuni tipi di microbi si trovano anche sulla normale superficie oculare. I microbi crescono sulle lenti e nei contenitori di stoccaggio e formano "biofilm" adesivi che li proteggono dalla pulizia e dalla rimozione.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b753c/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif ITAL-1-START3 ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7535/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7514/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7531/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b752b/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7537/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b753e/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif ITAL-1-START3 Movimento di una lente a contatto morbida sulla superficie del bulbo oculare e dietro le palpebre. La lente a contatto si muove con ogni movimento dello sguardo del bulbo oculare e anche in seguito al frequente ammiccamento. La quantità di attrito meccanico sulla superficie oculare è tipicamente aumentata nel portatore di lenti a contatto, anche quando il film lacrimale è sufficiente. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7539/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif ITAL-1-START3 Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b752f/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7529/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7527/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7540/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif ITAL-1-START3 La fine struttura dell'epitelio superficiale può subire un deterioramento quando è esposta all'influenza di una lente a contatto. Qui viene mostrato il cambiamento dell'epitelio congiuntivale bulbare nella zona di escursione di una lente a contatto morbida. Le cellule cubiche di superficie con cellule caliciformi intercalate per la produzione di mucine adesive all'acqua sono sostituite da un epitelio squamoso senza cellule caliciformi in un processo chiamato "metaplasia squamosa". https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b752d/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7544/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif ITAL-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4e84aa4a9960d83b7533/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png ITAL-1-START3 https://oscb-berlin.org/alt-ital-1-start4 daily 0.75 2018-06-10 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c710/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c70a/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c71e/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c720/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c718/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c712/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c71a/1512819831670/ ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c724/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c6fc/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c70e/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c702/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c70c/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6ef/1528660957342/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png ITAL-1-START4 - Copia della La Superficie Oculare in DETTAGLIO https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6f9/1528662485523/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg ITAL-1-START4 - Copia di MECCANISMI PATOGENETICI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6eb/1528662536554/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg ITAL-1-START4 - Copia di Sindromi DOLOROSE nella Malattia da Occhio Secco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6f3/1528661122025/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif ITAL-1-START4 - Copia di IL FILM Lacrimale https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6f5/1528661091282/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif ITAL-1-START4 - Copia di Il FLUSSO Lacrimale https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6ed/1528662604325/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITAL-1-START4 - Copia di COME l'Occhio Secco diventa Malattia ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6f1/1528661150090/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg ITAL-1-START4 - Copia di Le PALPEBRE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef4eb5758d4670efa6c6ea/5aef4eb5758d4670efa6c6f7/1528662431372/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg ITAL-1-START4 - Copia di SEGNI CLINICI https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c6fe/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c700/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif ITAL-1-START4 Il continuo turnover delle lacrime sulla superficie oculare va (1) dalla loro maggiore produzione nella ghiandola lacrimale alla (2) parte immediatamente visibile della cornea ed alla congiuntiva che deve costantemente bagnare (3) al sistema di drenaggio lacrimale che conduce le lacrime all'interno del naso. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c706/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif ITAL-1-START4 Un'occhiata al FILM LACRIMALE. La fase principale del film lacrimale sovrastante la cornea trasparente è composta dal fluido acquoso della ghiandola lacrimale. Sotto si trovano le numerose protrusioni simili a dita delle cellule di superficie. La loro cellula adiacente e le mucine secche e sciolte (filamenti rosa) costituiscono lo strato di mucina basale che lega l'acqua delle lacrime alla cellule della superficie oculare. Le mucine si mescolano con l'acqua e insieme formano un gel di acqua-mucina. La superficie del film lacrimale è ricoperta da uno strato di olio molto sottile costiuito dai lipidi delle ghiandole di Meibomio. Lo strato lipidico ha lo stesso spessore e la colorazione di un film d'olio su una pozza d'acqua. Una funzione principale dello strato di olio è di ritardare l'evaporazione della fase principale acquosa delle lacrime. Di conseguenza, un deficit lipidico dovuto ad una disfunzione delle ghiandole di Meibomio è attualmente considerato come il principale fattore causale della malattia dell'occhio secco. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c708/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif ITAL-1-START4 This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c704/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c716/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c714/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif ITAL-1-START4 Un OCCHIO SECCO moderato mostra in genere solo un lieve rossore della Congiuntiva e dei margini della palpebra che induce una condizione infiammatoria come descritto dal termine "cheratocongiuntivite sicca". Gli orifizi delle ghiandole lipidiche di Meibomio sono spesso ostruiti da secreto visibile o invisibile (che rappresenta la causa primaria più frequente della malattia dell'occhio secco). Il volume lacrimale è basso e il tessuto dell'epitelio della superficie oculare ha molti piccoli difetti, che si presentano come piccole macchie nella colorazione vitale con un colorante verde (fluoresceina) osservata in luce blu. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c6e8/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c722/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ITAL-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef4eb5758d4670efa6c71c/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif ITAL-1-START4 https://oscb-berlin.org/alt-f-1-start2 daily 0.75 2018-05-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf15/1512819831620/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf07/1512819831611/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf0d/1523819824811/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__A+LACK+of+OIL+is+typically+due+to+Dysfunction+of+the+Meibomian+Glands.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf1b/1525631117997/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf0f/1523113177752/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG-u.-ev.-Expression-der-Meibomdr%C3%BCsen-und-Augenlider_Einzel-BILDER_600pix-16-2_ENGLISCH.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf01/1512819831610/OSCB-GIF+FUNCTIONAL+UNIT+7%2C+BLINZELN+NEU+3x+LANGS%2C+NUR+Blinzeln+%2BLANGE+auf+mit+Tr%C3%A4nenFILM_VOLLFORMAT_25-6fps_CROP+-+GUT.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf13/1512819831618/GIF+Animation_LID-MARGIN-HYGIENE%2C-ENGLISCH_KLEIN-400pix-%2B-UNREGELM%C3%84SSIG_36-0%2C1_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdef6/1523113177747/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdefd/1512819831606/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf19/1512819831623/OSCB-Berlin.org_HYGIENE-is-a-CRUCIAL-FACTOR-in-CONTACT-LENS--WEAR.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf03/1525631117995/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Only-the-thin-homogeneous-Tear-FILM-guarantees-HEATH-and-clear-VISION-2x3D.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf11/1523113177754/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdee6/1525631117987/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+PATIENT+mit+Auge.jpg F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdefb/1512819831605/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf09/1523113177751/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef519daa4a9960d83bdee8/5aef519daa4a9960d83bdeed/1525003540262/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KONTAKTLINSEN_Beispiel+Foto_.jpg F-1-START2 - 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Copy of THERAPY OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef519daa4a9960d83bdee8/5aef519daa4a9960d83bdeeb/1525003500006/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg F-1-START2 - Copy of The OCULAR SURFACE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf17/1512819831621/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880-72%29+18-2+GIF+2x8Bit_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf0b/1512819831615/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_BASIC-INDICATIONS-FOR-A-SCLERAL-CONTACT-LENS_A-DEFICIENCY-of-OIL-the-most-frequent-cause-for-DRY-EYE-DISEASE.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdef9/1523113177749/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__OCULAR-SURFACE-%26-TEAR-FIM_STANDBILD-TEAR-FILM-aus-der-Animation_WEB-20_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdeff/1512819831608/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif F-1-START2 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef519daa4a9960d83bdf05/1512819831602/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg F-1-START2 https://oscb-berlin.org/alt-f-1-start3 daily 0.75 2018-05-31 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc55d/1519905603201/OSCB-Berlin.org_SCLERAL-CONTACT-LENSES-%28with-IMAGE-Courtesy-of-keratoconusinfo.wordpress.com%29.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc54f/1512819831635/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef51dd1ae6cf3823bdc531/5b100b45758d468095213eb1/1527778148358/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einge+wichtige+RISIKOFAKTOREN+f%C3%BCr+das+Trockene+Auge_GANZ+OHNE+Text_jpg6_.jpg F-1-START3 - 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Copy of CAUSATIVE FACTORS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef51dd1ae6cf3823bdc531/5aef51dd1ae6cf3823bdc532/1525165516307/OSCB-Bild_3._Ocular+Surface_The+BASIC+FUNCTIONAL+COMPLEXES+%2B+GLANDS+%26+LIDS++mit+TROPFEN+...+of+the+Ocular+Surface+%28aus+Concept-GIF%29.png F-1-START3 - Copy of BASIC FUNCTION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc553/1512819831638/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Ocular-Surface-Interaction-with-a-Contact-Lens-2.gif F-1-START3 Schematic diagram of a typical medium sized Soft Contact Lens on the Eye and partly behind the Lids. These lenses are termed corneo-scleral contact lenses because they reach over the cornea onto the sclera.. This is the most widely used type of contact lenses. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc557/1512819831642/OSCB-GIF_Augenoberfl%C3%A4che+ANIMATION_Blinzeln+%2B+AUGENBEWEGUNG+%2BKONTAKTLINSE+%2B+TEXT_%2880-72%2C11-0.8%29+GIF_.gif F-1-START3 Movement of a Soft Contact Lens on the Surface of the Eyeball and behind the Eyelids. The Contact Lens moves with every gaze movement of the eyeball and also upon the frequent eye blinks. The amount of mechanical friction at the ocular surface is typically increased in contact lens wear, even when the tear film is sufficient. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc549/1524398222209/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+makes+Epithelial+Alterations+Visible+in+the+Slit+Lamp%2C+FLUOrescense_SCHR%C3%84G.png F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc55b/1519905603198/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_CONTACT-LENSES---FITTING-and-TYPES_.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc545/1512819831630/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc53f/1512819831625/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc561/1525634037015/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc54b/1512819831632/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc55f/1512819831646/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Microbes-on-Contact-Lenses-can-hide-in-protective-BIOFILMS.gif F-1-START3 Insufficient Hygiene is a crucial factor in Contact Lens wear and results in a higher rate of ocular infections in contact lens wearers. Microbes can be introduced by the fingers of the wearer or from the use of tap water, that should be omitted. Certain types microbes also occur on the normal ocular surface. Microbes grow on the lenses and in the storage containers and form adhesive ´biofilms´ that protect them against cleaning and removal.   https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc52f/1525631194946/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+ARZT+mit+Auge.jpg F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc551/1512819831637/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc543/1512819831628/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc555/1512819831640/OSCB-Berlin.org_A-CONTACT-LENS-is-located-directly-on-the-Ocular-Surface-%28here-a-Rigid-Gas-Permeable-%28RGP%29-Lens-on-the-Cornea%29_Image-Courtesy-of-FLORENCE-MALET_WEB_%2B-LICHTSTRAHLEN.gif F-1-START3 ´Rigid´ Contact Lenses are typically smaller and exclusively rest on the cornea. They need a certain adaptation time for the wearer and are thus less widespread, but have superior inert material and optical quality. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc541/1512819831627/GIF-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_600pix-10-2__OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc54d/1512819831633/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNAL++RISK+FACTORS++for+Dry+Eye+Disease_NEU+quadratisch+2.png F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc547/1525631194952/OSCB-GIF_4.6+OSCB-GIF_Break-Up+FLUO_LIDER+%28FRONTAL%29+Animation+BLINZELN_%2815x72%29+UP-D+36-12+GIF.gif F-1-START3 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef51dd1ae6cf3823bdc559/1525457677911/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Chronic-Mechanical-Irritation-by-Contact-Lenses-can-cause-Bulbar-Conjunctival-Epithelial-Cell-Alterations-%28Squamous-Metaplasia%29.gif F-1-START3 The fine structure of the surface epithelium may undergo a deterioration where it is exposed to the influence of a Contact Lens. Shown here is the change of the bulbar conjunctival epithelium in the excursion zone of a soft Contact Lens. The cubical surface cells with interspersed goblet cells for the production of water-adhesive mucins are replaced by a squamous epithelium without goblet cells in a process termed ´squamous metaplasia´. https://oscb-berlin.org/alt-f-1-start4 daily 0.75 2018-05-21 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38da2/1512819831653/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dbe/1512819831674/OSCB-Berlin.org_ENVIRONMENTAL-RISK-FACTORS-impair-Ocular-Surface-Moisture-and-Health-%E2%80%A6--and-can-promote-Dry-Eye-Disease.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38db8/1512819831669/OSCB-Berlin.org_Clinical+SIGNS+in+Dry+Eye+Disease.png F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38daa/1512819831658/GIF-ANIMATION_The-Role-of-the-Ocular-Surface-in-the-Function-of-the-EYE_MONTAGE-Eigene-Zeichnung-Auge-schr%C3%A4g-seitlich-%2B-Bulbus-3D_Fertig_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38d9c/1512819831648/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38db6/1512819831667/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38db0/1512819831664/GIF+Animation_TYPICAL+SYMPTOMS+in+DRY+EYE+DISEASE_Typische+Symptome+beim+Trockenen+Auge_Bild+ENGLISCH+1-4v4_20-72_4-0.5fps_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38db2/1512819831665/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME-..DO-YOU-ALSO-SUFFER_600pix-23-2%2C5_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dc4/1524398324596/OSCB+LOGO+f%C3%BCr+VisitenKarte+%28aus+PPT+gespeichert%29.png F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d8b/1524325207723/OSCB-Bild_3._Ocular+Surface_Regulatory+Systems_NERVOUS+SYSTEM+mit+GEHIRN+%2B+HIRNNERVEN.jpg F-1-START4 - Copy of PAIN Syndromes in Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d91/1525631222031/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg F-1-START4 - Copy of The EYE LIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d8f/1524325164397/OSCB-Berlin.org_The+OCULAR+SURFACE+%28Anatomical+Unit%29+Neu+%2B+SECRETION-BATHING-DRAINAGE+%2B+Heller+%28Simple%29.png F-1-START4 - Copy of The Ocular Surface in DETAIL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d8d/1524394959479/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif F-1-START4 - Copy of HOW do we GET Dry Eye Disease ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d95/1525631222040/Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit_2-1_VOLL-2-1_.gif F-1-START4 - Copy of The Tear FLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d99/1525631222046/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg F-1-START4 - Copy of PATHOMECHANISMUS des Trockenen Auges https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d93/1525631222034/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_10.gif F-1-START4 - Copy of The Tear FILM https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5aef52462b6a281d80c38d8a/5aef52462b6a281d80c38d97/1525631222044/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg F-1-START4 - Copy of CLINICAL SIGNS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dac/1512819831659/ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_Tear+Film+LIPID-DEFICIENCY_EINZELBILDER%2C-ENGLISCH_%2B33-66-%2C400-40-1_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dc2/1512819831677/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38d9e/1512819831649/GIF_BILDER_OCULAR+SURFACE-Augenoberfl%C3%A4che-FOTO-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET-%2B-AUF-LABNOTES_ENGLISCH_28-72%2C-9-3sec-PSE.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38da8/1512819831656/GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2B+ABFLUSS%2C+DRAINAGE_25-5fps_.gif F-1-START4 This schematic animated diagram illustrates the principal eye lid function of tear spreading - actual tear drops occur in the palpebral fissure only during increased tear secretion. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38da6/1525631222052/GIF-OSCB-Berlin.org_Dry-Eye-Trockenes+Auge%2C+%28c%29ENK%2C+TEAR+FILM%2C+Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-900pix%2C-9-0%2C5_.gif F-1-START4 A glimpse into the TEAR FILM. The main phase of the Tear Film overlying the transparent cornea is composed of the aqueous fluid from the lacrimal gland. Below are the numerous finger-like protrusions of the surface cells. Their cell bound and and loose secreted mucins (pink filaments) constitute the basal mucin layer that binds the tear water to the ocular cell surface. Mucins mix with the water and together they form a water-mucin gel. The surface of the Tear Film is covered by a very narrow oil layer from the-lipids of the Meibomian glands. The lipid layer has the same thickness and coloring as an oil film on a puddle of water. A main function of the oil layer is to retard the evaporation of the aqueous main phase of the tears. Consequently a lipid deficiency due to a dysfunction of the Meibomian glands is presently reported as the main causative factor for Dry Eye Disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38d88/1525631222027/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SCIENTIST+mit+Auge.jpg F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dbc/1512819831672/OSCB-Bild_3.1.8_Ocular-Surface_REGULATORY-SYSTEMS-3_Different-Systems-regulate-...-auf-FOTO_NEU-ohne-MAUI-2000-HG_WEB_.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38da4/1525631222048/TEAR-FILM-%28and-Ocular-Surface%29_Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2_20+LINK+Bildchen.jpg F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dae/1512819831662/GIF-Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye+Disease_500pix-30-2_OSCB-Berlin.org_Dry+Eye+Disease%2C+Trockenes+Auge.gif F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38da0/1512819831651/OSCB-Bild_3.1.6_Only-a-MOIST-Cornea-can-stay-TRANSPARENT_WEB_.gif F-1-START4 The continuous Turnover of Tears at the Ocular Surface goes (1) from their main production in the lacrimal gland over (2) the readily visible cornea and conjunctiva that they must constantly bathe into (3) the lacrimal drainage system that drains the tears into the nose. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dba/1512819831670/ F-1-START4 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38db4/1512819831661/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_.gif F-1-START4 A moderate DRY EYE typically shows only mild redness of the Conjunctiva and Lid Margins that indiates an inflammatory condition as described by the term ´Keratoconjunctivitis sicca´. The orifices of the Meibomian oil glands are often obstructed by visible or invisible inspissated secretum (which represents the most frequent primary cause of Dry Eye Disease). The tear volume is low and the tissue of the Ocular Surface epithelium has many small defects, that occur as small spots in vital staining with a green stain (fluorescein) observed in blue light. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5aef52462b6a281d80c38dc0/1512819831675/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_WEB_.gif F-1-START4 https://oscb-berlin.org/alt-es-1-start0 daily 0.75 2018-07-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b355cf0aa4a99232a5228ec/1530223865335/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif ALT_ES-1-Start0 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b32a059aa4a990534ae4c90/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif ALT_ES-1-Start0 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PTG-1-START2 https://oscb-berlin.org/new-page-21 daily 0.75 2018-08-14 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b4b5ab01ae6cf6f420dd500/1534591224312/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg Dry Eye Disease https://oscb-berlin.org/dhomenew daily 0.75 2018-07-15 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b4b9db670a6ad5e777ff6a7/5b4b9db8562fa75c9631fb68/1531682239971/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg d-home-new https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b4b9e08f950b741b8bf08f1/1531682490324/FOTO+AUGE+OvalWEICH50Cut+%2B+OSCB__.jpg d-home-new - Willkommen ... Bienvenue ... WILLKOmMMEN zur Freien, Non-Profit, Educational Information-Portal des OCULAR SURFACE CENTER BERLIN - OSCB - Forschungszentrum für die Augenoberfläche Berlin über die Augenoberfläche, Kontaktlinsen und die Erkrankung des Trockenen Auges WILLKOMMEN dddd https://oscb-berlin.org/deu-facts-1 daily 0.75 2020-11-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6d3c6a41111900013b5ddc/1605622808742/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg FAKTEN & INFOS zum Trockenen Auge Der Tränenfilm auf der Augenoberfläche benötigt eine dünne Ölschicht (gelb, links im Bild) oben auf den wässrigen Tränen (blau, in der Mitte). Das Öl vermindert die Verdunstung des Tränenwassers. Ein Ölmangel erhöht die Verdunstung (blaue gewellte Pfeile, rechts im Bild) mit nachfolgender Reizung und Beschädigung des empfindlichen Gewebes (rötliche Färbung des Gewebes, rechts im Bild) sowie störenden Symptomen eines Trockenen Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b57923588251b03a8a08501/1605559883582/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif FAKTEN & INFOS zum Trockenen Auge Die Augenlider und der Lidschlag sind ebenso wichtig für die Gesundheit des Auges wie die Tränen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5d6674fd169eaa0001f38b86/1605682164382/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease___Augenoberfl%C3%A4che+und+Dr%C3%BCsen_Ocular+Surface+and+Glands_%2B+MGD+%2B+W%C3%BCste+%2B+Kamele+50%25_10+LINK+BILDCHEN_.jpg FAKTEN & INFOS zum Trockenen Auge - Das WICHTIGSTE - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5d6674b500e94f00014be8e4/1567154445310/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg FAKTEN & INFOS zum Trockenen Auge - FAKTEN über das Trockene Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5b5e2bf96d2a73ec3d32f656/1567154445308/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg FAKTEN & INFOS zum Trockenen Auge - Tieferer EINBLICK https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5b5e2baf1ae6cf84854a47cd/1567154445306/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg FAKTEN & INFOS zum Trockenen Auge - ÜBERBLICK https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5b5e2b3caa4a99bb7188cd6b/1567154445303/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg FAKTEN & INFOS zum Trockenen Auge - Kurzer BLICK https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b5e2a12aa4a99bb71889c9e/5b5e2aeb2b6a28400341288e/1581339852348/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg FAKTEN & INFOS zum Trockenen Auge - TROCKENES &amp; FEUCHTES Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b8a9015562fa736b2e6f086/1605616039007/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif FAKTEN & INFOS zum Trockenen Auge Die Augenoberfläche mit den dazugehörigen Augenlidern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b577ed370a6ad2a8eab5115/1605683689044/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_400-6-0%2C8_.gif FAKTEN & INFOS zum Trockenen Auge Einige lästige Symptome Trockener Augen sind hier schematisch dargestellt, z.B. verschwommenes Sehen, Trockenheitsgefühl, Rötung, Stechen oder Brennen der Augen - hier finden Sie mehr Informationen über typische Symptome. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b5ca9311ae6cf8485202e3e/1605608580045/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif FAKTEN & INFOS zum Trockenen Auge Viele austrocknende Umweltfaktoren kommen bei Büroarbeit zusammen und können zu einen “Büroauge” führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d667eeb169eaa0001f45ede/1567154445287/OSCB-Berlin.org_%2528c%2529ENK_Trockenes-Auge%252C-Dry-Eye-Disease_NORMALES%2BAUGE_Beispiel%2BFoto%2B%252B%2BW%25C3%25BCste%252BKamele%2B%252B%2BRand%2B-%2BHELLER_20_.jpg FAKTEN & INFOS zum Trockenen Auge https://oscb-berlin.org/fra-facts-1 daily 0.75 2018-09-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b64639b1ae6cfd495f44cc0/1532882040104/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif FRA - facts-1 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cbb/1534360545055/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_10+LINK+BILDCHEN+jpg6_.jpg FRA - facts-1 - QUELQUES INFORMATIONS<br>supplémentaires pour une<br>MEILLEURE COMPRÉHENSION More INFORMATION https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cb9/1534523717725/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg FRA - facts-1 - PERSPICACITÉ<br>... presque un petit <br>GLOSSAIRE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cb7/1534523589037/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg FRA - facts-1 - VUE GLOBALE ... pour la<br>compréhension <br>plus profonde https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cb5/1534523521439/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg FRA - facts-1 - VUE RAPIDE<br>... assez de tout<br>pour être informé https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cb3/1534359054064/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg FRA - facts-1 - Le DÉBUT<br>d'un GRAND VOYAGE<br>... avec des AMIS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b64639b1ae6cfd495f44cb0/5b64639b1ae6cfd495f44cb1/1534358660642/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____AUGE_10+LINK+BILDCHEN_.jpg FRA - facts-1 - FAITS<br>de Maladie des<br>YEUX SECS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b64639b1ae6cfd495f44cbe/1533376166715/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_Gelber-Zettel_500-7-0%2C8_.gif FRA - facts-1 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d67f92bd3c92c0001a8ec21/1567095086574/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand+-+HELLER+-+NUR+BILD_20_.jpg POL - Dry Eye Facts https://oscb-berlin.org/ara-0-home daily 0.75 2018-09-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abd7/1509126019911/ ARA-0-HOME Enfermedad de ojo seco https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b903054f950b7b78f8095b8/1536176240730/Dr.+Moatez+Billah+MEKKI%2C+ALGIERS_OPT+USM.png ARA-0-HOME Dr. Moatez Billah MEKKI, ALGIERS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abd3/1509126019907/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif ARA-0-HOME Lentes de contacto 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5b902f8f8a922d9c17c8abc1/5b902f8f8a922d9c17c8abc6/1519559909330/Augenoberfl%C3%A4che-mit-CORNEA-...-SEHR-SCH%C3%96NES-FOTO_Ret_WEB-5-2xHell_.gif ARA-0-HOME - Copy of Los TEMAS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abe8/1509200962447/IMPROVE+YOUR+TEACHING_Folie6_.JPG ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abd1/1509126019905/ ARA-0-HOME Película lagrimal https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abbf/1509204991035/OSCB-Berlin.org_DRY+EYE+DISEASE+and+Meibomian+Gland+Dysfunction+%28MGD%29.png ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b903b294fa51a1947e8c74d/1536178996181/Sihem-LAZREG%2C-Algeria_7-72_.gif ARA-0-HOME Sihem LAZREG, Algiers https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abe4/1509198007136/ResearchGate+LOGO.png ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abf0/1509126019933/ ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abdc/1509197711344/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abf4/1519584817709/BMSEK_Bilder_Graefe-%C3%9C_OPT_2014-06-18-11_AUSSCHNITT-Hell-2_.gif ARA-0-HOME - Berlín ... la Ciudad de     ALBRECHT VON GRAEFE     ... el Padre de la Oftalmología moderna . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abbd/1509204991032/TearFILM-Tears-%26-OCULAR-SURFACE__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_-%2B-TR%C3%84NENFILM-3D-NEU.gif ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abe6/1509198036980/ResearchGate+LOGO.png ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b9034bd89858352ec5876a2/1536177355176/Prof.-Mohammed-BELMEKKI%2C-Rabat%2C-MAROCCO_7-72_.gif ARA-0-HOME Mohammed BELMEKKI, Rabat https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abee/1509126019931/GIF+FUNCTIONAL+UNIT+8+f%C3%BCr+BANNER+ZENTRIERT+aus+7_..._TROCKENES+AUGE___8%29_NUR+REGULATION+2_30-2fps_.gif ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abcf/1527042697817/La+superficie+ocular+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30+AUSGESCHNITTEN+%2B+S%C3%A4ttigung_f%C3%BCr+BANNER%2C+STREIFEN+AUGENOBERFL%C3%84CHE+ATW+%2BUSM_.jpg ARA-0-HOME La superficie ocular https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abda/1509126019912/ ARA-0-HOME El margen palpebral https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abde/1509200974097/ ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8ac23/1510258551197/www.OSCB-Berlin.org%2F%23LINKS ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abea/1509126019926/OSCB-BILD_Augenoberfl%C3%A4che_EIN+NEUER+BLICK+auf+die+AUGENOBERFL%C3%84CHE++...BASIC+FUNCTIONAL+COMPLEX+%28%C3%9Cberblick+Funktionelle+Komplexe%29.png ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abe2/1509197803506/LinkedIn-LOGO-breit-s.png ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abd5/1509126019909/OSCB-GIF_MEIBOMDR%C3%9CSE%2C+Normal+%2B+Obstruktion+%28Ophthalmologe+2009%29_LIEGT+quer%2C+CROP+oben+f%C3%BCr+Banner_20-72_2-1fps_.gif ARA-0-HOME Glándulas de Meibomio y MGD https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abec/1509126019928/OSCB-Bild_3.1.8_Ocular+Surface_REGULATORY+SYSTEMS+3+auf+FOTO+vom+mir_VERSCHIEDENE+SYSTEME+REGULIEREN+die+Augenoberfl%C3%A4che_ ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b902f8f8a922d9c17c8abe0/1509197662867/Logo_DONATION-aus-Squarespace-HEARTBEAT.gif ARA-0-HOME https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5b903168352f530f54372b79/1536176529878/Dr.+Moatez+Billah+MEKKI%2C+ALGIERS_OPT+USM.png ARA-0-HOME Moatez Billah MEKKI, Algiers https://oscb-berlin.org/d-tear-subst-lipid-combi-artelac-complete daily 0.75 2018-09-27 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bacaaf3e5e5f021471b781e/1538043169506/Bausch%2BLomb_csm_PS_ARTELAC+COMPLETE_Gruppe+PACKUNGEN_300dpi_f90ed618a5.jpg B+L-Kombi Wasser+Öl-Artelac-Complete https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bacab1324a6941c66d68870/1538043187744/Bausch%2BLomb_csm_PS_ARTELAC+COMPLETE_TEXT.PNG B+L-Kombi Wasser+Öl-Artelac-Complete https://oscb-berlin.org/d-tear-subst-overview daily 0.75 2021-06-17 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e5aa6d4212d7f00cab3e632/1582999262722/OSCB-Berlin.org%2C+%28c%29+ENK_STERILE+DISPENSER+BOTTLE+%26+Single+Units%2C+EDO+for+Tear+Supplements+for+Dry+Eye_20_.jpg Tränenersatzmittel - ÜBERSICHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5a52f35a29bd1f2be914e8/1605868226072/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye%2C+Aqueous+Tear+Supplement%2C+HYALURONIC+ACID+BINDS+WATER_Trockenes+Auge%2C+Sicca%2C+W%C3%84SSRIGES+TR%C3%84NENERSATZMITTEL%2C+HYALURONS%C3%84URE+bindet+Wasser+2_20_.jpg Tränenersatzmittel - ÜBERSICHT In wässrigen Tränenersatzmitteln ist Wasser (H2O) gebunden an grosse wasserbindende Moleküle - oft Hyaluronsäure (HA) - damit es länger an der Augenoberfläche verbleibt, um sie feucht zu halten und zu schützen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdc83cc3bd3a53b5e894b05/1608287189773/OSCB-Berlin.org-%28c%29-ENK_Animation_Tr%C3%A4nenfilm-Hyperosmolarit%C3%A4t-%2B-Hypotone-Tr%C3%A4nenersatzmittel_2_20-22-0%2C8_.gif Tränenersatzmittel - ÜBERSICHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a235812be5b2164b832c4/1580155427435/%C3%9Cbersicht+TR%C3%84NENERSATZ+LINK-Bildchen_Neu+2_.jpg Tränenersatzmittel - ÜBERSICHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb34378c830257d563a6adb/1605783631327/%C3%9Cbersicht+TR%C3%84NENERSATZ+LINK-Bildchen_Neu+2_.jpg Tränenersatzmittel - ÜBERSICHT => direkt zur Auswahl verschiedener Tränenersatzmittel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e317dca0f6dd313bf61d0cc/1580301785680/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_+%281%29.jpg Tränenersatzmittel - ÜBERSICHT Konservierungsmittel können die empfindlichen Zellen der Augenoberfläche schädigen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c029eeb8a922dd6f318a38c/1579114068027/Augenoberfl%C3%A4che+OSCB+SCHEMA+Trockenes+Auge%2C+Dry+Eye_3gr%2BText+3NEU.jpg Tränenersatzmittel - ÜBERSICHT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d14f5381ac81a0001d3d1b9/1578770962147/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE_LINKBILDCHEN_Therapie_%2B+WASSERTROPFEN_2.jpg Tränenersatzmittel - ÜBERSICHT https://oscb-berlin.org/d-tear-subst-fluid-trb daily 0.75 2019-06-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf6a84b01698f0001a62fe0/1559668886425/AUGENOBERFL%C3%84CHE%2C+%28HORNHAUTkr%C3%BCmmung+mit+LIDERN%29+FOTO_+mit+TRB+BANNER.jpg TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf6c654511e9900019f3db6/1559677028440/ TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d55/1559668942182/TRB+CHEMEDICA_2012-PACKSHOT_vismed_rgb_72dpi.jpg TRB Dünnflüssig-Vismed VISMED® Enthält 0,18% Hyaluronsäure und wichtige Elektrolyte. Erhältlich als Packung mit 20, 60 oder 120 Einzeldosisampullen ohne Konservierungsmittel. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d51/1535886101678/TRB_2012-LOGO-vismed-LIGHT-rvb.jpg TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d4f/1535886101677/TRB+CHEMEDICA_2012-logo-VISMED-rvb.jpg TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d59/1559669040941/TRB+CHEMEDICA_2012-packshot_vismed_MULTI_rgb_72dpi.jpg TRB Dünnflüssig-Vismed VISMED® MULTI enthält 0,18% Natriumhyaluronat und wichtige Elektrolyte. Erhältlich als Mehrdosisbehältnis mit 10 ml ohne Konservierungsstoffe. Steril bis zu 3 Monate nach Öffnung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d53/1535886101680/TRB_2012-LOGO-vismed-MULTI-rvb.jpg TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d57/1559668996148/TRB+CHEMEDICA_2012-packshot_vismed_LIGHT_rgb_72dpi.jpg TRB Dünnflüssig-Vismed VISMED® LIGHT enthält 0,1% Natriumhyaluronat und wichtige Elektrolyte. Erhältlich als Mehrdosisbehältnis mit 15 ml. Steril bis zu 3 Monate nach Öffnung. VISMED® LIGHT wird geschützt durch sanfte und gut verträgliche Konservierungsmittel. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d5d/1535886101688/TRB+Chemedica_ABBILDUNG_Hyaluronic+Acid%2C+trb_hyaluronic_01+Plastizit%C3%A4t+.PNG TRB Dünnflüssig-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf6c6b4511e9900019f5013/1559677550422/Vislube-TRB-Chemedica_PACKUNG+mit+EDOs_360px.jpg TRB Dünnflüssig-Vismed VISLUBE® Enthält 0,18% Hyaluronsäure und wichtige Elektrolyte. Erhältlich als Packung mit 20, 60 oder 120 Einzeldosisampullen ohne Konservierungsmittel. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bff932dcd8366b036c04d5b/1535886101687/TRB+Chemedica_ABBILDUNG_Hyaluronic+Acid%2C+water_retention.gif TRB Dünnflüssig-Vismed https://oscb-berlin.org/d-tear-subst-gel-trb daily 0.75 2019-06-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c648/1535881166620/TRB+Chemedica_ABBILDUNG_Hyaluronic+Acid%2C+water_retention.gif TRB -Gel-Vismed Wasserbindung Hyaluronsäure ist ein langkettiges Glykosaminglykan aus den Molekülen Glukurinsäure und N-Azetylglukosamin. Hyaluronsäure bindet Wassermoleküle, daraus ergeben sich wichtige Funktionen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c642/1535888184799/2012-LOGO-vismed-GEL+MULTI-rvb.jpg TRB -Gel-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7b663174186000155cc8b/1559737973583/AUGENOBERFL%C3%84CHE%2C+%28HORNHAUTkr%C3%BCmmung+mit+LIDERN%29+FOTO_+mit+TRB+BANNER.jpg TRB -Gel-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c640/1535888184797/2012-LOGO-vismed-GEL-rvb.jpg TRB -Gel-Vismed https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c64a/1535881731916/TRB+Chemedica_ABBILDUNG_Hyaluronic+Acid%2C+trb_hyaluronic_01+Plastizit%C3%A4t+.PNG TRB -Gel-Vismed Viskoelastizität Hyaluronsäure vereint die physikalischen Charakteristika von elastischen Festkörpern mit denen von viskösen Flüssigkeiten, d.h. sie ist viskoelastisch. Auch eine Mischung aus Hyaluronsäure und Wasser verhält sich viskoelastisch. Dadurch bildet sie in Ruhe eine befeuchtende Schicht auf dem Auge und kann beim Lidschlag die mechanische Reibung zwischen Augenlid und Augapfel vermindern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c644/1559739139473/TRB+CHEMEDICA_2012-PACKSHOT_vismed_rgb_72dpi.jpg TRB -Gel-Vismed VISMED® GEL erhältlich in Packungen mit 20 und 60 Einmaldosen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5bffc4f50e2e72870560c646/1559739151576/TRB+CHEMEDICA_2012-packshot_vismed_GEL+MULTI_rgb_72dpi.jpg TRB -Gel-Vismed VISMED® GEL MULTI Enthält 0,3% Hyaluronsäure und wichtige Elektrolyte. Ohne Konservierungsmittel. Erhältlich als Mehrdosisbehältnis mit 10 ml. https://oscb-berlin.org/d-tear-subst-lipid-pure-optima daily 0.75 2019-11-24 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0058d92b6a2804ad48226b/1543526695563/TearsAgain+SENSITIVE+Liposomen-SPRAY_OPTIMA+Banner.jpg Optima Öl-TearsAgain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c005b668985834e42c6b217/1543527282011/TearsAgain+Liposomen-SPRAY_OPTIMA+Banner.jpg Optima Öl-TearsAgain https://oscb-berlin.org/d-therapy-overview daily 0.75 2020-11-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0ecbd888251b9da85b9562/1580155203047/BildELEMENT+SYSTEME+HORMON+und+IMMUN+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0ea35003ce6433b4922a53/1580155203021/BildELEMENT+AugenLIDER+BLINZELN+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0ea3b20ebbe8104e631ee0/1580155203028/BildELEMENT+W%C3%84SSRIGE+Tr%C3%A4nendr%C3%BCse+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0eb966cd8366aa67dab67f/1580155203044/BildELEMENT+Augenoberfl%C3%A4che+RISIKOFAKTOREN%2C+INterne+RECHTS+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0eb9494fa51abe99bb5945/1580155203024/BildELEMENT+Augenoberfl%C3%A4che+RISIKOFAKTOREN%2C+EXterne+RECHTS+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0eb36c758d460d17849591/1580155203018/BildELEMENT+Augenoberfl%C3%A4che+RISIKOFAKTOREN%2C+EXterne+LINKS+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0ea3fb4fa51abe99b9d9c3/1580155203034/BildELEMENT+%C3%96L+MEIBOMdr%C3%BCse+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0f81d18a922d33f5e5f88a/1580155203031/BildELEMENT+TR%C3%84NENFilm+MANGEL+gr+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0ecb7eb8a0456b59ef0dda/1580155203014/BildELEMENT+NERVENSYSTEM%2C+Regulation+SCHMERZ+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0f87e01ae6cfa8b7b79e85/1580155203041/BildELEMENT+Augenoberfl%C3%A4che+ZELLEN+OHNE+Tr%C3%A4nenfilm+gr+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f9574fd13ab7749e56dc2c9/1605199245927/OSCB-Berlin.org_ANIMATION_Krankheits-Faktoren+THERAPIE-OPTIONEN_aus+AUGENOBERFL%C3%84CHE+OSCB+SCHEMA+Normal+%2B+Trockenes+Auge+%2B+SICCA+DIAGNOSTIK___6+%28mehr+Beschriftung%29_20-21-1%2C5_.gif THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? Die animierte Abbildung zeigt, wie grundlegende Funktionen die Augengesundheit erhalten und ihre Störung zur Entstehung des Trockenen Auges führen. Gleichzeitig ergeben sich aus dem Verständnis der Krankheitsentstehung Ansätze für eine erfolgreiche Therapie. => direkt zu Krankheits-Faktoren und Therapie Auswahl https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f9577e0586eae39613e3826/1605199245930/OSCB-Berlin.org_Schema+Krankheits-Faktoren+THERAPIE-OPTIONEN____6_30_.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0eb2e521c67c1ded53c9cf/1580155203037/BildELEMENT+Augenoberfl%C3%A4che+RISIKOFAKTOREN%2C+Interne+LINKS+50%25+Trockenes+Auge%2C+Dry+Eye+.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d56b024769d1e0001742042/1580155203008/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge_NEU%2B2_16%2BLINK%2BBILDCHEN_Therapie_.jpg THERAPIE - was kann ich TUN ... gegen mein Trockenes Auge ? https://oscb-berlin.org/d-mdd-blepharitis-overview daily 0.75 2020-12-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a2bb43796b24423fd5944/1609231414960/Meibomddr%C3%BCsen+SPEZIALISIERTE+Therapie_10+LINK+BILDCHEN.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge => direkt zu Meibomdrüsen APPARATIVE Therapie beim Arzt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a29def3730241dff39fb9/1580155585879/Meibomddr%C3%BCsen+BASIS+Therapie_10+LINK+BILDCHEN.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c27ba060ebbe85745d241e8/1554661894816/www.OSCB-Berlin.org_DEMODEX+Milben+und+BAKTERIEN+Normale+Flora+auf+dem+Lidrand+bei+Meibomdr%C3%BCsen+St%C3%B6rung%2C+MDD%2C+MGD+und+BLEPHARITIS+2_20_.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc25e77e6d49a06bbdf5b2d/1606584153953/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Dry%2BEye%2BDisease%2C%2BTrockenes%2BAuge_Meibomdr%C3%BCsen%2BDysfunktion%2B%28MDD%2C%2BMGD%29%2Bmit%2Bverstopften%2Bund%2Birregul%C3%A4ren%2B%C3%96ffnungen%2Beingedicktes%2BSekret%2Bwird%2Bausgepresst_20_.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da702f4ffea006e2c552b39/1606841443035/OSCB-Berlin.org---%28c%29-ENK_Bildung-von-ABLAGERUNGEN-auf-dem-Lidrand_ANIMATION_400-21-1%2C5_.gif MEIBOMDRÜSEN - Ölmangel - Trockenes Auge Schematische animierte Darstellung über die Entstehung einiger wichtiger krankhafter Veränderungen am Rand des Augenlides. Diese treten bei verschiedenen chronischen Erkrankungen des Auges auf, unter anderem bei der chronischen Meibomdrüsen Dysfunktion (MDD). => hier finden Sie ein Foto von Ablagerungen und Verkrustungen auf dem Lidrand und an den Wimpern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a2a7651f223209a157e17/1580155585882/Meibomddr%C3%BCsen+SPEZIALISIERTE+Therapie_10+LINK+BILDCHEN.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e287e92d2e9fa1df8f7e082/1609231393502/Meibomdr%C3%BCsen+BASIS+Therapie_.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge => direkt zu Meibomdrüsen BASIS Therapie Zuhause https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d220c032be4ab11c5a72a/1554661894810/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____%C3%96l-Mangel+f%C3%BChrt+zu+erh%C3%B6hter+Verdunstung+mit+Trockenem+Auge_20_.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5caa288d15fcc0da6e58352b/1554661894803/Konjunktivaler+R%C3%96TUNGSGRAD+auf+MGD%2C+MDD%2C+Blepharitis%2C+Trockenes+Auge%2C+Sicca+Montage_BANNER_.jpg MEIBOMDRÜSEN - Ölmangel - Trockenes Auge https://oscb-berlin.org/d-mdd-lipiflow daily 0.75 2019-07-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c03f6ff2b6a2807fb48feab/1544706757131/TearScience+LIPIFLOW+Patient+%2B+Applicator.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0e3b23562fa7678542bdab/1544706757129/TearScience+LIPILOW+GER%C3%84T+Computer_download_OPT_.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c040067352f531f773fcbe3/1544380751882/TearScience+LIPIFLOW+mit+PATIENTIN_lf_patient%402x.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c03fbc7758d46bbd4841687/1544380751884/LIPIFLOW+FUNKTION+ANIMATION+als+GIF_download_lf-animation-xl.gif Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d7c766d2a7379672c7813/1544706757125/JnJ+TearScience+LipiFLOW+ACTIVATOR-tour_mobile_OPT_.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d7e1221c67c5de4dbdb54/1544706757123/LipiFLOW+Image+Gallery_Screenshot_JPG12_.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c03f47ccd83661235f6047c/1562577655708/TearScience+LIPILOW+GER%C3%84T+Computer_download_.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0e3a110ebbe8549dbf8002/1544706757128/LipiVIEW+II+DER+AUGENARZT+am+LipiVIEW+Image+Gallery_Download.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c03fdcb1ae6cf280947b58c/1544380751876/Titelzeile+JnJ+Vision+TearScience.jpg Meibomdrüsen - LipiFLOW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c267b52f950b760dd396725/1546025836188/LIPIFLOW+FUNKTION+ANIMATION+als+GIF_download_lf-animation-xl.gif Meibomdrüsen - LipiFLOW https://oscb-berlin.org/d-mdd-lipiview daily 0.75 2019-07-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d71198a922dfd48132b17/1544708253456/JnJ+TearScience+LipiVIEW+FOTO+23+Meibomdr%C3%BCse+in+DUAL+MODE_dmi-Dual-Mode+DMI_full.jpg Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d6ecc6d2a7379672bc729/1544708253451/JnJ+TearScience+LipiVIEW+FOTO+Meibomdr%C3%BCse+in+DYNAMIC+IMAGING_dmi-dynamic_full.jpg Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d6d2b562fa7678539f7fd/1544708253446/LipiVIEW+II+Image+Gallery_Download.jpg Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d75590e2e72365cac64ba/1544708253458/JnJ+TEarScience+LIPIVIEW+II+Report+Funktionen.jpg Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d68614d7a9c6ed430dc77/1562577602445/JnJ+TearScience+product-hero-LIPIVIEW%402x.png Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d70460e2e72365cac21ba/1544708253454/JnJ+TearScience+LipiVIEW+FOTO+2+Meibomdr%C3%BCse+in+TRANSILLUMINATION_dmi-adaptive_full.jpg Meibomdrüsen - LipiVIEW https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c0d614f6d2a7379672b1bd7/1544386445234/Titelzeile+JnJ+Vision+TearScience.jpg Meibomdrüsen - LipiVIEW https://oscb-berlin.org/d-diagnosis-overview daily 0.75 2021-03-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c32030c8a922d582298ef06/1580155158337/Diagnose-Symbolbild_TR%C3%84NEN+-+PRODUKTION.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b74649de796402b66c075/1580155158340/Diagnostik+DIAGNOSTISCHE+EXPRESSION+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7cb69fe29ef95f643f2ecd/1580155158374/OSCB-Berlin.org_Lidrand-Parallele-Conjunctivale-FALTEN-%28LIPCOF%29-der-Bindehaut-treten-auf-durch-Besch%C3%A4digung-des-Bindegewebes-bei-Chronischem-Trockenen-Auge_3+9-19_20_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b73829de796402b66b272/1580155158334/Diagnostik+ENTZ%C3%9CNDUNGS+MARKER%2C+MMP9+Test+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c16b3554d7a9c14f018cfde/1580155158397/Spezialisierte+Ger%C3%A4te+f%C3%BCr+die+Meibographie_%28c%29ENK%2C+www.OSCB-Berlin.org_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b6fee6f60f948972c35b0/1580155158317/Diagnostik+OSMOLARIT%C3%84T+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c14132f1ae6cf84447b27c0/1580155158380/Animation_Trocknes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d78bcd7913a06645e3515b4/1580155158301/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_2_.jpg DIAGNOSE - Klinische TESTS => direkt zur Übersicht nach KLINISCHER REIHENFOLGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d79fa5217444913dd72a94d/1580155158347/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE+%C3%9Cbersicht_3_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d77d13659827503c52174c5/1580155158356/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_NICHT-Invasive+BUT+%28NIBUT%29_20__.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b6de22fa7f53d66824477/1580155158313/Diagnostik+TR%C3%84NEN+MENGE+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c14fe76c2241bba3e6dba7c/1614858858939/SCHIRMER-Test%2C+Tr%C3%A4nen%2C+Trockenes+Auge%2C+Sicca%2C+Tears%2C+Tear+Film+Dry+Eye+Disease_Ohne+Text+mit+STREIFEN_20_%28c%29+ENK%2C+www.OSCB-Berlin.org__.jpg DIAGNOSE - Klinische TESTS Der umgeknickte Teststreifen wird im lateralen Drittel über den Lidrand in den unteren Fornix gesteckt. Dann werden die Augen während der 5 Minuten des Test weitgehend geschlossen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c16b5a4032be42f6131286b/1580155158393/Dual+Mode+DMI+Meibography_LipiVIEW+und+LipiSCAN%2C+TearScience_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b7327f47ce20cb5b63eb1/1580155158331/Diagnostik+R%C3%96TUNG+der+Bindhaut+Test+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d77d9d3d37b0b39d7837fd4/1580155158359/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_Der+TR%C3%84NEN+MENISKUS+ist+ein+Indikator+f%C3%BCr+die+Tr%C3%A4nen-MENGE+auf+dem+Auge_20_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7cb4129d991000aacd0c90/1580155158377/OSCB-GIF_3.7_Augenoberfl%C3%A4che-ANIMATION_Blinzeln-%2B-AUGENBEWEGUNG-%2B-TEXT_%2880-72%2C12-2%29_9-19%2C-8-12-0%2C5_-GIF.gif DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c173c334fa51ae704dfeadb/1580155158390/OSCB-Berlin.org_DIAGNOSTISCHE-Expression-der-Meibomdr%C3%BCsen-mit-einem-standardisierten-Druckapplikator--%28Meibomian-Gland-Evaluator%2C-MGE%29.gif DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b6bedd481a14f79c731c2/1580155158307/Diagnostik+LIPIDSCHICHT+DICKE+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7a038291bd3e25ca4f758d/1580155158328/Diagnostik+LIPCOF+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c13a2f40e2e728dc552263e/1580155158350/Inkompletter+Lidschlag%2C+Lidschlag+FREQUENZ%2C+LIPIVIEW_LINK-BILDCHEN_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c13f38e758d46179198b0f3/1580155158368/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__VITALF%C3%84RBUNG+macht+Zellsch%C3%A4den+sichtbar+an+der+Spaltlampe.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b72596f60f948972c5d2d/1580155158320/Diagnostik+F-BUT+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b7478c2c49d24c0b42016/1580155158343/Diagnostik+MEIBOGRAPHIE+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c13a510352f53ad3e3938e1/1615752468131/VOLLAUTOMATISCHE+INTERFEROMETRIE+und+Analyse+der+Tr%C3%A4nenfilm-Lipidschicht+Dicke_www.OSCB-Berlin.org_20_.jpg DIAGNOSE - Klinische TESTS Im oberen Foto ist die Lipidschicht ausreichend dick (Avg.ICU 90) erkennbar an den deutlichen Blau- und Gold-Tönen der Interferenzfarben, die die Dicke anzeigen. Im unteren Bild ist die Lipidschicht viel zu dünn (Avg. ICU 35) erkennbar an der sehr blassen, fast abwesenden Färbung. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b72c2c2c49d24c0b40384/1580155158325/Diagnostik+VITAL+F%C3%84RBUNG+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7937d133efba23f9e08d1d/1580155158371/OSCB-Berlin.org_%28c%29-by-ENK-Erich-u-Nadja-Knop_Dry+Eye%2C+Trockenes+Auge_OXFORD+Scheme+for+Vital+Staining%2C+Vitalf%C3%A4rbung%2C+Cornea+Epithelium+Kornea%2C+Hornhautepithel_20_.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c14f0798a922db9dfab5a2e/1580155158362/Die+Wasser-Verdunstung+beim+EVAPORATIVEN+Trockenen+Auge+f%C3%BChrt+zu+Tr%C3%A4nen-Film+HYPEROSMOLARIT%C3%84T_www.OSCB-Berlin.org_20_.jpg DIAGNOSE - Klinische TESTS Bei Erhöhter Verdunstung (blaue Pfeile) des Tränenwassers werden die gelösten Stoffe (Salze und Proteine - in der Abb. als weisse Kugeln) stärker konzentriert. Dies führt zu lokal dünnem mit erhöhter Salzkonzentration (Hyperosmolarität), und damit zu Augen Brennen und Zellschädigung. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b7802e1468f750f57e2f3/1580155158304/Diagnostik+LIPIDSCHLAG+ANALYSE+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d7b6d122fa7f53d668237f2/1580155158310/Diagnostik+NI-BUT+%2B+Text.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fcce43bd235d37878c5d599/1607263374924/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_20-18-0%2C2_.gif DIAGNOSE - Klinische TESTS Das Aufbrechen des dünnen Tränenfilms wird sichtbar, wenn die Tränen mit dem Fluorescein-Farbstoff angefärbt werden, der im blauen Licht betrachtet wird. Ein Aufbrechen ist sichtbar als dunkler Bereich (hier in der Mitte des "C" vom OSCB-Overlay). Das Aufbrechen des Tränenfilms ist der Stimulus, der einen Lidschlag auslöst, um einen neuen Tränenfilm zu verteilen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ce2f49b2fb08f0001b68f91/1580155158383/BonOptic_ABNAHME+an+AUGE_Inflamma_dry_taking_sample.jpg DIAGNOSE - Klinische TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d14feb5d3b36700012f69e4/1580155158298/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg DIAGNOSE - Klinische TESTS https://oscb-berlin.org/d-dry-eye-management daily 0.75 2020-11-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c65e2ce8165f53e880e47c9/1580155014326/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg Trockenes Auge - WAS NUN ? - MANAGEMENT ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c10edbbf950b79e77da23b1/1580155014336/OSCB+DIAGNOSE+%C3%9Cbersicht+3_mit+ZETTEL.jpg Trockenes Auge - WAS NUN ? - MANAGEMENT ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c65dfaf7817f790fb4d7eb0/1580155014333/LINK-BILDCHEN_QUESTIONNAIRE+Neu.jpg Trockenes Auge - WAS NUN ? - MANAGEMENT ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c6821d1419202ebf6eb9723/1580155014339/OSCB-Berlin.org_THERAPIE%2C+Tr%C3%A4nenersatzittel+Tropfen+auf+Trockenes+Auge_20cm_.jpg Trockenes Auge - WAS NUN ? - MANAGEMENT ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8469942694431a6b4ae611/1580155014323/Diagnostik+und+Therapie%2C+Abbildung+f%C3%BCr+LINK+BANNER_3+f%C3%BCr+Erkennen+%26+Behandeln%2C+Patient%2C+Arzt%2C+Fragezeichen%2C+Schlange_.jpg Trockenes Auge - WAS NUN ? - MANAGEMENT ! https://oscb-berlin.org/d-diagnosis-4 daily 0.75 2020-11-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044254/1491161341738/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04423f/1604564989230/ d-Diagnose-4 GEWEBESCHÄDEN Eine schematische Zeichnung eines Auges mit mehreren Lid Parallelen Falten (LIPCOF, durch Pfeile gekennzeichnet). Sie liegen über dem hinteren Lidrand innerhalb des Tränenmeniskus (blaue Pfeile). (Die Lidränder sind leicht nach außen gedreht, um die hintere Lidkante mit dem Tränenmeniskus darzustellen) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044220/1602056186889/ d-Diagnose-4 GEWEBESCHÄDEN Erhöhte mechanische Reibung ist ein hauptsächlicher pathogenetischer Faktor für Augenoberflächenerkrankungen. Reibung tritt bei allen Bewegungen des Augapfels relativ zur knöchernen Orbita und zu den Augenlidern auf, insbesondere beim Lidschlag. Pathologisch erhöhte Reibung tritt auf wenn die normale Schmierung durch den Tränenfilm aufgrund der Pathologie z. B. beim Trockenen Auge oder aufgrund äusserer Faktoren wie einer Kontaktlinse verringert wird. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044252/1496399221355/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04424a/1604567432424/ d-Diagnose-4 GEWEBESCHÄDEN Die Grundstruktur der Konjunktiva besteht aus dem luminalen Epithel und dem darunter liegenden Geflecht aus Kollagenfasern im Bindegewebe der Lamina propria. In den Spalten zwischen den Fasern befinden sich Stromazellen und Abwehrzellen des angeborenen und spezifischen Immunsystems zusammen mit umgehenden Strukturen wie Blutgefäßen (links in der Mitte), Lymphgefäßen und Nervenfasern (schwache gelbe Linien). Das Enzym MMP9 spaltet die langen Kollagenfasern in Fragmente und beschädigt so die strukturelle Basis des Gewebes. Der biologische Sinn liegt darin, mehr Platz für die eigentlich schützenden ´Entzündungszellen´ zu schaffen. Probleme treten dann auf, wenn die Entzündung chronisch wird und somit alle Versuche einer endgültigen, geordneten Reparatur des Gewebes untergräbt. Dies führt zu einer zunehmenden Beschädigung und damit zu einer Gewebelockerung der Bindehaut, die als Conjunctivochalasis bezeichnet wird https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044226/1602078418191/Zones+of+highest+FRICTION+at+the+Ocular+Surface.png d-Diagnose-4 GEWEBESCHÄDEN Reibung tritt hauptsächlich an der Bulbusoberfläche innerhalb der Lidspalte und am hinteren Rand der Augenlider auf, hauptsächlich im oberen Augenlid. Unter normalen Bedingungen steht ausreichend ´Schmierung´ durch eine ausreichende Menge von Tränenflüssigkeit und zusätzliche lubrikative Substanzen zur Verfügung. Unter Bedingungen erhöhter Reibung, wie z.B. beim Trockenen Auge oder beim Tragen von Kontaktlinsen, können die normalen Bewegungen von Augapfel und Lidern gegeneinander bereits Epithelschäden verursachen. Dies kann durch 'Vitalfärbung' mit verschiedenen Farbstoffen sichtbar gemacht werden, da die verletzten Zellen die Färbung aufnehmen und die normalen nicht. Die Vitalfärbung der erhabenen Epithellippe der ´Lid Wiper´ (Lidwischer) an der hinteren Lidkante wird von Donald KORB und Kollegen als Lid Wiper Epitheliopathy (LWE) bezeichnet. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044228/1602057649142/ d-Diagnose-4 GEWEBESCHÄDEN Eine schematische Zeichnung zeigt das Bild von Fluorescein-gefärbten Epithelveränderungen, die als kleine Punkte auftreten. Die Größe der gefärbten Punkte, die prinzipiell von einzelnen gefärbten Zellen stammen, ist hier in der Zeichnung etwas zu groß, um sie besser sichtbar zu machen. Spezifische Färbungsmuster können wie hier bandförmig innerhalb der Lidspalte auftreten. Färbungsmuster können jeweils Vermutungen zum Mechanismus der pathologischen Veränderung zulassen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04422e/1491073465511/ d-Diagnose-4 GEWEBESCHÄDEN Die VITALFÄRBUNG von epithelialen Veränderungen der Augenoberfläche wird beispielsweise semiquantitativ bewertet, wobei die Menge der Färbung den einzelnen gefärbten Zellen entspricht, durch Vergleich mit einer Tabelle, der bestimmten Modellgrade anzeigt, abgeschätzt wird. Ein beliebtes Bewertungssystem ist der OXFORD SCORE, da dieser einfach zu verwenden ist und relativ zuverlässige Ergebnisse liefert. Die hier gezeigten Färbungsintensität stellt schematisch eine mittlere (Grad 2) Färbung auf der Oxford-Skala dar. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04423d/1491122218885/ d-Diagnose-4 GEWEBESCHÄDEN Bengalrosa Vitalfärbung des L id Wiper Epitheliu m des marginalen Konjunktiva. Die Färbung ist intensiv rötlich-rosa . Die lebenswichtige Färbung des Lidwischers ist pathologisch und wird als Lidwischer-Epitheliopathie (LID Wiper Epitheliopathy, LWE) bezeichnet, wohingegen die Färbung der dünnen Linie (Pfeile) an der Außenseite normal ist und die physiologisch färbbare L ine von MAR X anzeigt . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f369c6f23cb7d37c9e29c51/1597415003873/OSCB-Bild_2_Meibomian+Gland_Histology+of+Obstructive+Meibomian+Gland+Dysfunction+%28MGD%29+Ophthalmologe+2009.png d-Diagnose-4 GEWEBESCHÄDEN Lichtmikroskopische Darstellung einer geschädigten Meibomdrüse (rechts) im Vergleich mit einer normalen Drüse (links) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04425c/1491576466943/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa3eec26d618612a18d6426/5fa3eec3c1d01e0ea803f04d/1604579050077/Animation_Schema-Gewebeschaden%2C-Reizung%2C-Entz%C3%BCndung-3-%28Vitalf%C3%A4rbung-unauff%C3%A4lliger-%2B-weniger-R%C3%B6tung%29_10-9-0%2C7_.gif d-Diagnose-4 GEWEBESCHÄDEN - Epithel-Störung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa3eec26d618612a18d6426/5fa3f5e8c4d06f178cb77534/1604580869817/OSCB-Berlin.org+%28c%29+ENK_Meibographie%2C+Meibomian+Gland+Drop-Out_10+LINK+Bildchen_.jpg d-Diagnose-4 GEWEBESCHÄDEN - Meibomdrüse/ Meibogaphie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa3eec26d618612a18d6426/5fa3f0ad3f2f0f1df1704300/1604579542872/OSCB-Berlin.org_Some+TYPICAL+SIGNS+in+Dry+Eye+Disease+%28Vital-Staining-%2B-FOTO%29%2C-NEU_WEB_10+LINK+Bildchen_.jpg d-Diagnose-4 GEWEBESCHÄDEN - Vitalfärbung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa3eec26d618612a18d6426/5fa3f1c4c53bc851e576e8dd/1604581187363/OSCB-Berlin.org_Lidrand-Parallele-Conjunctivale-FALTEN-%28LIPCOF%29-der-Bindehaut-treten-auf-durch-Besch%C3%A4digung-des-Bindegewebes-bei-Chronischem-Trockenen-Auge_3+OHNE+Text_10+LINK+BiLDCHEN_.jpg d-Diagnose-4 GEWEBESCHÄDEN - Bindehaut Stroma/ LIPCOF https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa3eec26d618612a18d6426/5fa3f413239d614df96c11d0/1604580485141/OSCB-Berlin.org+%28c%29+ENK_Dry+Eye+Disease_DIAGNOSIS_Inflammation+Mediators+MMP9+CLINICAL+TEST_10+LINK+Bildchen_.jpg d-Diagnose-4 GEWEBESCHÄDEN - Entzündung/ MMP9 Test https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044233/1491231118949/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044247/1604567108114/ d-Diagnose-4 GEWEBESCHÄDEN Ausgeprägte LIPCOF Falten im Tränenmeniskus können die Oberkante des Meniskus nach oben verschieben und so eine erhöhte Tränenmenge auf dem Auge vortäuschen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044222/1602077655081/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04424c/1604568230201/OSCB-Bild_6_Dry+Eye+Disease_PATHOPHYSIOLOGY_LIPCOF+Folds+in+CONJUNCTIVOCHALASIS+are+based+on+a+MMP9+Proteases+in+Chronic+Inflammation_.png d-Diagnose-4 GEWEBESCHÄDEN Lid-Parallele Conjunctivale Falten (LIPCOF) treten auf, wenn das strukturelle Kollagengeflecht des Bindegewebes (Lamina propria) in der Konjunktiva durch Proteinasen abgebaut wird, hauptsächlich Matrix-Metalloproteinase 9 (MMP9). Die Lockerung der Bindehaut wird als "Conjunctivochalasis" bezeichnet. MMP9 wird zunehmend während des chronischen Entzündungsprozesses beim Trockenen Auge aktiviert. Die lockere Bindehaut wird dann durch die relativ scharfe hintere Lidkante ´aufgeschaufelt´ und auf den hinteren Lidrand gefaltet. Hier schematisch direkt neben der Conjunctivochalasis eine Zone mit ´Normal´ er Kollagenstruktur angezeigt. Es ist jedoch davon auszugehen, dass die gesamte Bindehaut von dieser Zerstörung bei chronischer trockener Augenerkrankung relativ homogen betroffen ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044237/1491234202995/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044239/1491122107459/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+-+FLUORESCEIN+stains+Cornea+better+than+Conjunctiva.png d-Diagnose-4 GEWEBESCHÄDEN FLUORESCEIN Vitalfärbung des L id Wiper Epitheliu m des marginalen Konjunktiva. Die Färbung ist intensiv blaugrün. Fluorescein färbt die pathologische Lid Wiper Epitheliopathie (LWE), liegt aber auch auf der Tarsal Conjunctiva in der Mitte des Bildes und grenzt teilweise Substrukturen wie Krypten und andere Oberflächenunregelmäßigkeiten ab. Diese Überlagerung von Fluorescein auf dem Epithel ist keine echte Färbung, da, wie im nächsten Bild mit Lissamine Green-Färbung zu sehen ist, die Tarsalkonjunktiva bei solchen Patienten typischerweise unverändert und gesund ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04424e/1604569794682/ d-Diagnose-4 GEWEBESCHÄDEN Ein geeigneter Test zur Bestimmung erhöhter Spiegel des proteinzerstörenden Enzyms Matrix-Metalloproteinase 9 (MMP9) ist verfügbar. Durch eine Immunreaktion wird angezeigt, ob der MMP9-Spiegel über dem normalen Bereich liegt. Der MMP9-Test kann somit einen chronischen gewebezerstörenden Entzündungsprozesses anzeigen, der eine therapeutische Intervention erfordert, selbst wenn klinische Anzeichen einer Gewebezerstörung noch nicht aufgetreten sind. Der MMP9-Test bietet daher möglicherweise einen neuen präventiven Ansatz für die Behandlung von Krankheiten des trockenen Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04422c/1491072830470/ d-Diagnose-4 GEWEBESCHÄDEN Die Schwere der Augenoberflächenfärbung , die aufgrund pathologischer epithelialer Veränderungen auftritt, wird typischerweise gemäß der Menge der gefärbten Zellen bestimmt. Die Stelle scheint auch eine gewisse Bedeutung zu haben, da die Nasenfärbung (oberes Bild) typischerweise mild und unspezifisch ist, wohingegen die zeitliche Färbung (unteres Bild), dh an einer Stelle, an der die frischen Tränen aus den Tränendrüsenausscheidungen typischerweise in den Bindehautsack fließen deutet auf eine schwerere Erkrankung hin und ist etwas spezifisch für die Erkrankung des trockenen Auges (Schematische Darstellungen gemäß Beobachtungen von UCHIYAMA und Kollegen 2009 ). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04421e/1491573732234/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+-+MAIN+CAUSATIVE+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044258/1491161554688/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044230/1602084196015/Zones+of+highest+FRICTION+at+the+Ocular+Surface.png d-Diagnose-4 GEWEBESCHÄDEN Mechanishe Reibung tritt hauptsächlich an der Bulbus-Oberfläche innerhalb der Lidspalte und an der hinteren Lidkante auf, hauptsächlich im oberen Augenlid, aber bis zu einem gewissen Grad auch im unteren Lid. Die verdickte Epithellippe des Lidwischers. Sie reicht am hinteren Rand bis zu ca. 10 mm nach innen und die Region des Augenlides, die in Kontakt mit dem Bulbus ist. Die auftretende Reibungskraft beim Lidschlag konzentriert sich hier auf eine relativ kleine Fläche. Normalerweise wird die Reibung durch ein ausreichendes Tränenvolumen und ein reichhaltiges Muzin-Wasser-Gel durch viele Becherzellen und Becherzellkrypten (siehe 2 Abbildungen rechts), ausreichend begrenzt. Bei erhöhter Reibung, wie beim Trockenen Auge und bei Kontaktlinsentragen, tritt eine pathologisch hohe mechanische Reibung und damit Veränderung und Verwundung des Epithels am Lidwischer auf. Lid Wiper Epitheliopathy (LWE) ist das erste und empfindlichste Zeichen für erhöhte Mechanische Reibung an der Augenoberfläche (KORB und Kollegen 2000). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044243/1604506599443/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04425a/1491161731774/ d-Diagnose-4 GEWEBESCHÄDEN Topographer-Systeme sind in der Regel weiter fortgeschritten. Sie bieten in der Regel fortschrittlichere Beleuchtungs- und Visualisierungstechniken und eine bessere Bildqualität sowie Messungen und eine strukturierte Dokumentation, die den täglichen Effektiver und angenehmer gestalten können. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044224/1602056087503/HYPEROSMOLARITY+induces+SURFACE+DAMAGE+and+INFLAMMATION.png d-Diagnose-4 GEWEBESCHÄDEN Die schematische Darstellung zeigt den Einfluss einer lokalen Hyperosmolarität, durch Verdunstung von Tränenwasser mit Ansammlung der verbleibenden Tränensalze und Proteine (graue Kreise) und lokalem Aufbrechen des Tränenfilms. Die Hyperosmolarität zieht Wasser aus den Epithelzellen mit potentieller Schrumpfung und Zellbeschädigung. Dies stellt ein Gefahrensignal dar und löst eine Entzündungsreaktion mit Bildung von Entzündungsmediatoren aus. Bei chronischer Tränenfilmstörung mit Hyperosmolarität kann sich ein entzündungsförderndes Milieu bilden, das zum Ausbruch oder zur Verschlimmerung eines chronischen trockenen Auges führen kann. (Aus schematischen Gründen ist die lokale Hyperosmolaritätszone hier viel zu klein - es kann davon ausgegangen werden, dass auch eine kleine lokale Hyperosmolarität bereits mehrere oder viele Zellen gleichzeitig beeinflusst). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04423b/1491123432774/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_VITAL+STAINING+of+the+Ocular+Surface+-+LISSAMINE+GREEN+stains+the+Conjunctiva+very+well.png d-Diagnose-4 GEWEBESCHÄDEN Lissamingrün Vitalfärbung des L id Wiper Epitheliu m des marginalen Konjunktiva. Die Färbung ist intensiv dunkelgrün und färbt die Bindehaut sehr gut und intensiv. Hier macht es die pathologische Lid Wiper Epitheliopathy (LWE) sichtbar, da die Bindehautzellen, die sich bei erhöhten Reibungszuständen wie Augentrockenheit und Kontaktlinsenabnutzung verändern, den Fleck aufnehmen, wohingegen die anderen normalen Bindehautzellen an der Tarsal Conjunctiva in Die Bildmitte färbt nicht. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04421c/1491578261536/ d-Diagnose-4 GEWEBESCHÄDEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044245/1605527146954/ d-Diagnose-4 GEWEBESCHÄDEN Lid-Parallele Conjunctivale Falten (LIPCOF) treten auf, wenn das strukturgebende Kollagengeflecht des Bindegewebes (Lamina propria) der Bindehaut durch Proteinasen abgebaut wird, hauptsächlich Matrix-Metalloproteinase 9 (MMP9). Dies dient dazu Platz im Gewebe zu schaffen für die Entzündungszellen, die beim chronisch entzündlichen Trockenen Auge aus den Gefässen in das Gewebe einwandern. Diese Entzündung muss nicht klinisch sichtbar sein, da auch bereits bei subklinischer Entzündung Matrix Metalloproteinasen aktiviert werden. Die Lockerung der Bindehaut wird als "Conjunctivochalasis" bezeichnet. Das lockere Gewebe wird dann durch die relativ scharfe hintere Lidkante ´aufgeschaufelt´ und auf dem Lidrand aufgefaltet. Der Einfachheit halber wird hier (Abb. links) direkt neben der ´Conjunctivochalasis´ eine Zone mit ´Normal´er -Kollagenstruktur angezeigt. Es ist jedoch davon auszugehen, dass die gesamte Bindehaut von dieser Beschädigung bei chronischem Trockenen Auge relativ homogen betroffen ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04425e/1491577205874/ d-Diagnose-4 GEWEBESCHÄDEN Fortschrittliche Beleuchtungstechniken ermöglichen die Abbildung der Meibomschen Drüsen in beispielloser Klarheit. Dadurch kann die genaue Struktur normaler Meibom-Drüsen und genaue Information über deren Änderung beim Drüsenabbruch erhalten werden. Bilder: Mit freundlicher Genehmigung von TearScience Inc. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044241/1604507602156/ d-Diagnose-4 GEWEBESCHÄDEN Erhöhte Reibung begünstigt LIPCOF Falten https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e04422a/1602079087190/ d-Diagnose-4 GEWEBESCHÄDEN Eine schematische Zeichnung auf zellulärer Ebene zeigt das Bild von mit Fluoreszein-gefärbten epithelialen Veränderungen, die als kleine Punkte auftreten. Die gefärbten Punkte, stammen prinzipiell von einzelnen gefärbten Zellen und sind hier als polyedrische Objekte dargestellt. Oft betrifft dies mehr als eine einzelne Zelle, so dass die gefärbten Flecken größer als ein Zelldurchmesser sind. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c12447d2b6a28a28e044256/1491161421607/ d-Diagnose-4 GEWEBESCHÄDEN https://oscb-berlin.org/d-mdd-lipiscan daily 0.75 2019-07-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c24ccbdc2241b301d152a7c/1545915592507/JnJ+TearScience+LipiVIEW+FOTO+Meibomdr%C3%BCse+in+DYNAMIC+IMAGING_dmi-dynamic_full.jpg Meibomdrüsen - LipiSCAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c24cf48758d4652b3837b5c/1545916241070/JnJ+TearScience+LipiVIEW+FOTO+23+Meibomdr%C3%BCse+in+DUAL+MODE_dmi-Dual-Mode+DMI_full.jpg Meibomdrüsen - LipiSCAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c125be0f950b7c158ff1a8f/1562577770580/TearScience+LipiSCAN+zur+hochaufl%C3%B6senden+Betrachtung+der+MEIBOMDR%C3%9CSEN_TearScience.JPG Meibomdrüsen - LipiSCAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c24d6fccd8366d27f6ce406/1545918219955/LipiSCAN+Bildzusammenstellung_JnJ+TearScience_.jpg Meibomdrüsen - LipiSCAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c125ac5562fa7d650d6c985/1545916769488/Titelzeile+JnJ+Vision+TearScience.jpg Meibomdrüsen - LipiSCAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c24ced68a922df266bb0ef2/1545916127832/JnJ+TearScience+LipiVIEW+FOTO+2+Meibomdr%C3%BCse+in+TRANSILLUMINATION_dmi-adaptive_full.jpg Meibomdrüsen - LipiSCAN https://oscb-berlin.org/d-diagnosis-3 daily 0.75 2020-11-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ad7/1604607030746/ d-Diagnose-3 TRÄNENFILM Tränenfilm Osmolarität ist ein wichtiger klinischer Parameter und wichtiger sekundärer pathogenetischer Faktorbeim Trockenen Auge. Die Messung kann heutzutage schnell und einfach mit einem hangehaltenen GErät (TearLab) durchgeführt werden. Es benutzt sterile Einmal Messspitzen zur Aufnahme der Tränenflüssigkeit. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817acd/1491130271674/ d-Diagnose-3 TRÄNENFILM Zustände an der Augenoberfläche mit einem Mangel an Tränenfilm Lipiden haben eine ausgedünnte Ölschicht auf dem Tränenfilm, die dann zu einem Verlust der Verdunstungshemmung führt. Das Tränenwasser verdunstet dann schneller (blaue Pfeile) und die gelösten Stoffe (Salze und Proteine - in der Abb. als weisse Kugeln) werden stärker konzentriert. In der Folge (1) reduziert sich die Menge der Tränen auf dem Auge und der Tränen-Meniskus sinkt, was typischerweise zu verringerter ´Schmierung´ zwischen Augenlid und Augapfel beim Lidschlag führt, und damit zu einer erhöhten mechanischen Reibung. Zusätzlich (2) führt die Konzentrierung der Salze in den Tränen zu einer erhöhten Osmolarität, auch als ´Hyperosmolarität´ bezeichnet. Diese übt einen Wasser-entziehenden osmotischen Effekt auf die empfindlichen Zellen aus, der sie schädigt. Sowohl erhöhte Reibung wie auch erhöhte Osmolarität stellen einen Entzündungsreiz dar. und können zum Fortschreiten des Trockenen Auges zu einer chronischen Entzündungskrankheit beitragen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa418572373445f2805513d/5fa4200bfc425957fcb4f743/1604591657369/OSCB-Berlin.org+%28c%29+ENK_OSMOMETRY__Gelber+Zettel_10_.jpg d-Diagnose-3 TRÄNENFILM - Osmolaritätsmessung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa418572373445f2805513d/5fa41d9be878382292b72eb8/1604591116103/OSCB-Berlin.org+%28c%29+ENK_LIPID+LAYER+INTERFEROMETRY__Gelber+Zettel_10_.jpg d-Diagnose-3 TRÄNENFILM - Lipidschicht Interferometrie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa418572373445f2805513d/5fa41ae02630ec1f3976e007/1604590335593/OSCB-Berlin.org+%28c%29+ENK_FLUO+BUT__Gelber+Zettel_10_.jpg d-Diagnose-3 TRÄNENFILM - Fluo-BUT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fa418572373445f2805513d/5fa419974df2866998a522d8/1604589996377/NIBUT_Auge+Hellfeld%2C+nur+Placido-Ringe+%2B+DISTORSION_BonOptic+Polaris_Gelber+Zettel_10_.jpg d-Diagnose-3 TRÄNENFILM - NI-BUT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ad5/1604605890454/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png d-Diagnose-3 TRÄNENFILM Die schematische Abbildung zeigt die Pathophysiology beim Trockenen Auge, auf Basis des HOLISTISCHEN DYNAMISCHEN KONZEPTS. Grundlegende Kausale Faktoren stören die Bildung eines stabilen Tränenfilms durch Mangel an Tränenflüssigkeit oder durch gestörte Ausbreitung zu einem stabilen Film. Dies ist die typische Primäre Pathologie. Die Tränenfilmstörung führt zu sekundären schädlichen Faktoren wie Hyperosmolarität des Tränenfilms und erhöhter Reibung beim Lidschlag durch verminderte Schmierung. Schließlich führt dies zur zweiten Primären Pathologie der Beschädigung des Gewebes. Diese gilt ebenfalls als primär, da ein Gewebeschaden unter bestimmten Umständen auch zuerst auftreten kann und dann zu einer gestörten Anhaftung der Tränen an das Gewebe führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817acb/1604596100805/ d-Diagnose-3 TRÄNENFILM Das interferometrische Bild der Tränenfilm-Lipidschicht, das hier mit dem TearScience Lipiview erstellt wurde, zeigt, dass ein Tränenfilm mit normaler Dicke eine Mischung von Interferenzfarben aufweist, die hauptsächlich rötlich-golden sind (oberes Bild). Dies entspricht einer durchschnittlichen Dicke von 90 Nanometern. Die Lipidschicht im unteren Bild ist zu schmal, wie an der grauen Interferenzfarbe" zu erkennen ist - die automatische Messung zeigt eine durchschnittliche Dicke von 35 Nanometern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ac3/1491064222425/ d-Diagnose-3 TRÄNENFILM The superficial layer of the tear film is composed of lipids with possibly some minor amounts of associated proteins. The lipid film is very thin but is still conceptually separated into a much thicker outer layer of non-polar lipids that appear to represent the ´lid on the pot of warm tears´ that retards aqueous evaporation. Underneath is a much thinner sub-layer of non-polar lipids, possibly with minor contents of proteins, that can connect the above layer to the underlying aqueous phase. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ad3/1604603572365/ d-Diagnose-3 TRÄNENFILM Die schematische Abbildung aus einem Artikel von Mitgliedern der OSCB aus dem Jahr 2005 in "The Ocular Surface" erklärt die wichtigsten Schritte in der Pathogenese der immun-modulierten chronischen mukosalen Entzündung beim Trockenen Auge. Durch eine Schädigung des Epithels der Augenoberfläche werden Entzündungsmediatoren gebildet, die eine Reaktion des Schutzgewebes in Gang setzen, um den pathogenen Reiz zu beseitigen. Von hier aus wird eine Abfolge von sekundären Ereignissen ausgelöst, die (1) eine Anhebung von Antigen-Präsentationsmolekülen und (2) von Zelladhäsionsmolekülen, die den Einstrom von Zellen aus dem Gefäßkompartiment in das Gewebe induzieren und dort einen zerstörerischen Weg durch das Gewebe bahnen, sowie (3) die Aktivierung von bindegewebsabbauenden Enzymen (Matrix-Metalloproteinasen, hauptsächlich MMP9) im vermeintlich besten Interesse, den entzündungsschützenden Zellen Platz zu schaffen, umfassen. All dies wäre kein großes Problem ... wenn die Veränderung nur akut und nicht chronisch fortschreitend wäre - was aber unglücklicherweise der typische Fall des Trockenen Auges ist. Daher ist die typische Entwicklung hier, dass sich die beabsichtigte Schutzreaktion in eine chronische immunologische Schleimhautentzündung umwandeln kann. Diese wird durch Lymphzellen, als normalem Schutzbestandteil des Gewebes, immunmoduliert wird und damit sehr stark und therapieresistent gegen konventionelle Sicca-Therapie mit ausschließlich Tränenersatzmitteln etc.. Dies ist die Grundlage für die sinnvolle Anwendung einer anti-entzündlichen Therapie beim chronischen Trockenen Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ad1/1604603992395/ d-Diagnose-3 TRÄNENFILM In der Pathogenese des Trockenen Auges, ist die Hyperosmolarität (rechts in der Abb.) ein wichtiger Sekundärer Pathogenetischer Faktor. Hyperosmolarität ist die Folge der Primären Pathologie der Tränenfilmstörung mit Lipidmangel, die zu erhöhter Verdunstung des Tränenwassers führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c139ac9c2241b21d2e4658e/1604595086807/Dicke+der+LIPID-SCHICHT+auf+dem+Tr%C3%A4nenfilm.jpg d-Diagnose-3 TRÄNENFILM Die schematische Darstellung einer normalen Tränenfilm-Lipidschicht in Interferometrie zeigt ein wirbelndes Muster von rötlich-goldenen Interferenzfarben. Die Interferenz ist typischerweise am besten zu sehen, wenn das Raumlicht gedimmt ist. Weiter unten finden Sie ein echtes Foto einer Interferometrie. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ac9/1492957196901/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_Tear+Film+LIPID+LAYER+Analysis+and+Corneal+Topography%2C+TEARSCOPE+Advanced%2C+HOCHKANT_k%C3%BCrzer.png d-Diagnose-3 TRÄNENFILM The Analysis of the Tear Film LIPID LAYER (TFLL) by INTERFEROMETRY is already available since the 1980s by a simple to use handheld device - the TearScope, that was invented by the Tear Film Specialist Jean-Pierre GUILLON. Apart from estimating the thickness of the Lipid Layer it is also possible to obtain the Non-Invasive Tear Film BREAK-UP Time (NI-BUT). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817abf/1491070778561/ d-Diagnose-3 TRÄNENFILM TOPOGRAPHERS are Multi-Purpose devices that are stand-alone, are typically equipped with different illumination systems for different purposes and are connected to a computer with an appropriate software system for evaluation and storage of examination results. Certainly very useful for Dry Eye Diagnostics is the possibility to perform Non -Invasive Tear Film Break-Up (NI-BUT) measurements that allow the measurement of Tear Film stability without interfering with it by addition of marker any substances. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817ac1/1491064235862/ d-Diagnose-3 TRÄNENFILM The view of pro-ocular Tear FILM as a basically three layered liquid film is the leading concept for roughly the last 70 years since Eugene WOLFFS original description in 1946 ... and this concept still appears to hold true. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c138d31aa4a99798c817abd/1492968420101/ d-Diagnose-3 TRÄNENFILM When the Tear Film BREAK-UP Time (BUT) is estimated conventionally, the vital stain FLUORESCEIN is used to make the tear film visible in order to see its Break-Up - this is termed Fluorescent BUT (F-BUT). A Break-Up typically occurs in a small area and quickly becomes larger. In the region of the Break-Up the epithelial cells are exposed to the ambient air and are prone to dry out. The exposure of the epithelium is immediately sensed by the sensory nerves and initiates an eye blink to remove the old ruptured tear film and to spread a new one. https://oscb-berlin.org/d-lacrimal-gland-dysfunction daily 0.75 2021-03-04 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce1ebe74a40730fbc11e0e/1607343815125/OSCB-Berlin.org+%28c%29+ENK_PUNCTUM+PLUGS+various+types+-+PUNCTUM+PLUGS+verschiedene+Typen_AIVIMED_20_.jpg TRÄNENDRÜSEN Störung - Starker Wassermangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce46f7978da30c562b4e4d/1607364922279/PUNCTUM+PLUGS_10+LINK+BILDCHEN_.jpg TRÄNENDRÜSEN Störung - Starker Wassermangel => direkt zur Therapie Auswahl https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb7ed932830bd2f526028b9/1606496955402/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_20-12-1%2C3_.gif TRÄNENDRÜSEN Störung - Starker Wassermangel Auge und ableitende Tränenwege. Die ableitenden Tränenwege beginnen an jedem Lid an dem Tränenpünktchen, das weit nasal in den Tränensee (Tränen-Meniskus) eintaucht um Tränenflüssigkeit absaugen zu können. Die Tränenkanäle verlaufen von hier im Lidrand zur Nase und vereinigen sich kurz vor dem Tränensack, der mit dem Tränen-Nasengang in der Nase mündet. Bei sehr starkem wässrigen Tränenmangel ist ein Tränenwegs Stöpsel (Punctum Plug) sinnvoll, um den Abtransport der Tränenflüssigkeit vom Auge zu vermindern. Dadurch erhöht sich der Tränenmeniskus auf dem Unterlid (siehe animierte Abbildung), was als TMH-Wert (engl: ´tear meniscus height´ ) klinisch gemessen wird. (=> hier finden Sie mehr Informationen mit histologischen Bildern) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce44cee43f2b00a8d65d61/1607353643918/PUNCTUM+PLUGS_10+LINK+BILDCHEN_.jpg TRÄNENDRÜSEN Störung - Starker Wassermangel => hier finden Sie einige Therapie Optionen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce480b33187724c41fb6be/1607354493142/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_CROP-Schmal-2_35-9-1_.gif TRÄNENDRÜSEN Störung - Starker Wassermangel https://oscb-berlin.org/d-surface-damage-inflammation daily 0.75 2020-11-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c16912c4ae23769a9174402/1580155803373/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif Oberflächenschaden, Entzündung, Funktionsverlust https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8484d8f6cdad589e1e1bd4/1580155803370/OSCB-Berlin.org_%2528c%2529%2BENK-%2BErich%2Band%2BNadja%2BKnop_Dry%2BEye%2BDisease%252C%2BTrockenes%2BAuge_ERKENNEN%2Bund%2BBEHANDELN%2B12%2BGEWEBESCHADEN%2Bmit%2BKSP%2B-%2BFREI%2B3%2Bf%25C3%25BCr%2BBANNER_.jpg Oberflächenschaden, Entzündung, Funktionsverlust https://oscb-berlin.org/d-nerves-hormones-immunesystem daily 0.75 2020-11-15 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c16a1534ae23769a9180a4d/1580155841824/Regulatorische+Systeme+ANIMATION+%28Download%29_%28c%29+ENK%2C+www.OSCB-Berlin.org_.gif Regulations-Systeme https://oscb-berlin.org/d-tear-subst-fluid-ps-blupan daily 0.75 2018-12-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c28fedc0ebbe85745dda5d3/1546190558338/PharmaStulln+BluPan+EDO+%2B+Sterildispenser+Symbolbild+.jpg Tränenersatz - dünnflüssig-BLUPAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c2904e270a6adae0b24be80/1546192107669/PharmaStulln+BluPan+INDIVIDUELLE+BED%C3%9CRFNISSE+.jpg Tränenersatz - dünnflüssig-BLUPAN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c28fecccd836676a1a08247/1546191171636/PharmaStulln+BLUPAN+Die+gute+L%C3%B6sung+f%C3%BCr+Trockene+Augen.jpg Tränenersatz - dünnflüssig-BLUPAN https://oscb-berlin.org/d-external-risk-factors daily 0.75 2021-03-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c3b62c76d2a73d481f4f149/1580155384338/OSCB-Berlin.org_No+Contact+Lens+Wear+in+Dry+Eye+Disease_Kein+Kontaktlinsentragen+beim+Trockenen+Auge_%28c%29ENK_20_.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c3b5cd488251b8b3c6ab28e/1580155384326/OSCB-Berlin.org_Dietary+Improvement+against+Dry+Eye+Disease_Ausreichende+Di%C3%A4t%2C+Trinkmenge+gegen+das+Trockene+Auge_%28c%29ENK_20_.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c2922bf8985832b197702f7/1580155384319/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_30_%2Cjpg.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c3b3c656d2a73d481f37d9a/1580155384335/PLANTS+against+Dry+and+Polluted+Air+in+Dry+Eye+Disease_PFLANZEN+geben+Trockene+und+Staubige+Luft+beim+Trockenen+Auge_20__.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d14d4a4155d6100018f1124/1580155384332/OSCB-Berlin.org_BRILLE+mit+VERDUNSTUNGSSCHUTZ+gegen+das+Trockene+Auge%2C+Spectacles+with+EVAPORATION+PROTECTION+for+Dry+Eye+Disease_%28c%29+ENK_2_20_.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d6cc79d4f45fb0001300e26/1580155384329/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbe60923c02f22b9ddd1c30/1606312128061/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29%2B%281%29.gif HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c3b75496d2a73d481f5e649/1580155384323/OSCB-Berlin.org_Ocular+Fitness+to+fight+Dry+Eye+Disease_Augen+Fitness+gegen+das+Trockenen+Auge_%28c%29ENK_20_.jpg HAUSMITTEL gegen Risikofaktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d14f3fb2f809b00016c831d/1580155384315/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE_LINKBILDCHEN_Austrocknender+Risikofaktoren_3_.jpg HAUSMITTEL gegen Risikofaktoren https://oscb-berlin.org/frageboegen daily 0.75 2020-11-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c5d4f961905f45535b1e3e1/1580155059953/LINK-BILDCHEN_QUESTIONNAIRE+Neu.jpg FRAGEBÖGEN zum Trockenen Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d14fdfea09c330001187cf9/1580155059949/FRAGEBOGEN_10+LINK+BILDCHEN.jpg FRAGEBÖGEN zum Trockenen Auge https://oscb-berlin.org/geraete-material daily 0.75 2019-06-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5c8b55024e17b636e5feef58/5d1a2510953d6d0001a10f96/1561994566217/bon_logo_.gif Geräte & Material https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5c8b55024e17b636e5feef58/5d1901905fe7fa00014bb47e/1561921747034/JENOPHTHALMO_LOGO+Quad+3.jpg Geräte & Material https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5c8b55024e17b636e5feef58/5c95314bfa0d604bd0578a97/1553281396464/EYETEC_Optikger%C3%A4te+VERTRIEB%2C+L%C3%BCbeck_LOGO+3_.jpg Geräte & Material https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5c8b55024e17b636e5feef58/5c8e6c16f9619a65370418fe/1561919644097/TRUSETAL+Verbandstoffwerk+-+AUGENPRODUKTE+%2B+EYESFIRST.jpg Geräte & Material https://oscb-berlin.org/geraete-mat-bonoptic daily 0.75 2019-06-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf805d7ed12770001e24bb5/1559760830345/BonOptic+IPL+GANZES+GER%C3%84T+%2B+Oberteil.jpg BONOPTIC - Geräte und Material 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https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ce2c8d4de8b320001981b4b/1559761068375/BonOptic_ABNAHME+an+AUGE_Inflamma_dry_taking_sample.jpg BONOPTIC - Geräte und Material https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf8ee0f4cc51b0001e092d3/1559817773536/Bon-ANTARES+Topographer_Bild+AUSWERTUNG_.jpg BONOPTIC - Geräte und Material https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ce29454a265cb00011cf0f0/1559761019512/BonOptic_TEARLAB_Foto%2Bder%2BMESSUNG%2Bam%2BAuge_im1594-_tear_collection.jpg BONOPTIC - Geräte und Material https://oscb-berlin.org/d-tear-subst-lipid-plus-pharmastulln-hylan daily 0.75 2019-11-27 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9673f915fcc0e0be7b782b/1553363971173/PharmaStulln%2C+EDO+Plastikbeh%C3%A4lter+-+%C3%96FFNUNG+1+EDO+%2B+ARZT+Symbol+%2B+REZEPT+HYLAN.jpg PS-Wässrig-Zusatz-Hylan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9bd1dce79c70a32fa8de23/1553715690516/PharmaStulln_HYLAN+EDO+Gebrauchsanleitung+mit+Wieder-VERSCHLUSS+3.jpg PS-Wässrig-Zusatz-Hylan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9636974e17b612dddb5a6b/1553348275718/PharmaStulln_HYLAN+EDO+Gebrauchsanleitung+mit+Wieder-VERSCHLUSS+20.jpg PS-Wässrig-Zusatz-Hylan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9bd13471c10babca6a4265/1574841429780/HYLAN+%28EDO%29+Packung_PharmaStulln+2.jpg PS-Wässrig-Zusatz-Hylan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c96357515fcc0e0be7973a4/1553347999842/PHarmaStulln_LOGO+-+BANNER.jpg PS-Wässrig-Zusatz-Hylan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c96403ac67c2f0001ff9912/1553350728274/PharmaStulln%2C+EDO+Plastikbeh%C3%A4lter+-+%C3%96FFNUNG+mit+FINGERN%2C+KOLORIERT.jpg PS-Wässrig-Zusatz-Hylan https://oscb-berlin.org/d-tear-subst-liquid-ps-blupan daily 0.75 2019-07-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d10b58c5664b2000104cdbc/1561376170216/Bild+zu+MOVIE+%C3%BCber+BluPan+OSD+Flasche.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9689ff15fcc0e0be7c3e1f/1562578931441/FS_BLUpan_SOFT+Packungen_OSD_10ml_links.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9680f815fcc0e0be7bec1e/1560413486576/PharmaStulln+BluPan+SERIE+-EDO+%26+STERIL-DISPENSER_Packungen%2C+Download.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c968aee652deafd31e26d1d/1562579062744/PharmaStulln+BluPan+MEDICAL_Packungen+EDO+%2B+10ml%2C+Download.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c96849608522938214ddc21/1561376414818/PharmaStulln+BluPan+SERIE_Packungen%2C+Download.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c968a219140b79a9b339351/1560413363411/FS_BLUpan_MEDIUM+Packungen+EDO+%2B+10ml_.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c967d5ac83025368bedc116/1553366453814/PharmaStulln_BLUPAN_header.jpg PS-Wässrig-Blupan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c967efaf9619a337b7c8d42/1553366787062/PharmaStulln_SYMBOL+FREI+von+Konservierungsmitteln+%2B+GEEIGNET+f%C3%BCr+Kontaktlinsen+10.jpg PS-Wässrig-Blupan https://oscb-berlin.org/d-tear-subst-lipid-combi-pharmastulln-lipitear daily 0.75 2019-07-08 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c97f10c1972fb000105c3b3/1553461523045/PharmaStulln+LIPITEAR+mit+EDOs+aus+FLYER_20.jpg PS-Kombi Wasser+Öl-Lipitear https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c97ee98e79c70b6f14840df/1553460934670/PharmaStulln+LIPITEARS%2C+Micellen%2C+Schemazeichnung+aus+FLYER.jpg PS-Kombi Wasser+Öl-Lipitear https://oscb-berlin.org/trnenersatz-oel-omni-lipidspray daily 0.75 2019-03-26 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9a9a954192020170875b6c/1553636005948/OMNIVISION_BANNER.jpg Omni-Öl-Lipidspray https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9a8def8165f5fb73b52501/1553632758423/Omnitears+Lipidspray+N_Packung%2BFlasche_20.jpg Omni-Öl-Lipidspray https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9a909b6e9a7f7dacc07e78/1553633445078/Omni_LIPIDSPRAY+N%2C+Anwendungs-ZEICHNUNG+koloriert_20.jpg Omni-Öl-Lipidspray https://oscb-berlin.org/trnenersatz-gel-omni daily 0.75 2019-11-30 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9aa8136e9a7f0a4b06276a/1553639470966/Omni_Hylo+Vision_SafeDrop_GEL_oK_rgb_cef6785dfd.jpg Omni-Gel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9aa5671905f44fa98f9ea6/1553638786272/Omni+HYLOVISION+sine+GEL.jpg Omni-Gel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9a9a084785d396725f3ceb/1553635872669/OMNIVISION_BANNER.jpg Omni-Gel https://oscb-berlin.org/trfe-zusatz-trb-remogen-omega daily 0.75 2019-07-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9bd5849140b7336f79ee4e/1553716659548/TRB+Chemedica+Banner+%2B+Schrift_30_.PNG TRB-Zusatz-RemogenOmega https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9bd60ce5e5f08cc96ffee2/1561997636443/Remogen-Omega-TRB-Chemedica_Packung+mit+EDO_360px.jpg TRB-Zusatz-RemogenOmega https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5c9bde45aa4fb9000173513e/1553718876984/Omega3_TRB-TRB-Chemedica_360px.jpg TRB-Zusatz-RemogenOmega https://oscb-berlin.org/trfe-details daily 0.75 2020-11-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db6abf6c853f67fa18e9e29/1580155466657/OSCB-Berlin.org%2C+%28c%29+ENK_STERILE+DISPENSER+BOTTLE+%26+Single+Units%2C+EDO+for+Tear+Supplements+for+Dry+Eye_20_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d2441000ae23d00011bacac/1580155466631/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Hyaluronic+Acid%2C+different+chain+length%2C+HA%2C+HYALURONS%C3%84URE%2C+verschiedene+KONZENTRATION_20_.jpg Tränenersatzmittel - DETAILS Hyaluronsäure mit höherer Konzentration der Wasser-bindenden Moleküle (rechts) ist dickflüssiger/ höhere Viskosität - ggf. kann dies vorübergehend die Sicht leicht verschleiern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db73c0e209ead05326a4e82/1580155466634/OSCB-Berlin.org%2C+%28c%29+ENK_HIGHer+VISCOSITY+Tear+Supplement+for+more+severe+Dry+Eye_20_2_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db757dc36843074a3695bd9/1580155466641/OSCB-Berlin.org%2C+%28c%29+ENK_Tear+Supplments+can+have+different+INTERINDIVIDUAL+Tolerabiliy_20_2_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdb03974e17b63d040f06ac/1580155466644/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye%2C+Aqueous+Tear+Supplement%2C+HYALURONIC+ACID+BINDS+WATER+in+the+VITREOUS+BODY_Trockenes+Auge%2C+Sicca%2C+W%C3%84SSRIGES+TR%C3%84NENERSATZMITTEL%2C+HYALURONS%C3%84URE+bindet+Wasser+im+GLASK%C3%96RPER_20_.jpg Tränenersatzmittel - DETAILS Ein wichtiger körpereigener Wasser-bindender Baustoff im Körper ist das Molekül Hyaluronsäure. Es kommt z.B. im Glaskörper des Auges vor wie hier dargestellt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f4cb6ffb40a322269499456/1598863127654/OSCB-Berlin-org+%28c%29+ENK_VISCOSITY+in+tear+supplements%2C+Viskosit%C3%A4t+bei+Tr%C3%A4nenersatzmitteln_10_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d24417327b7e10001d99521/1580155466651/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Hyaluronic+Acid%2C+different+chain+length%2C+HA%2C+HYALURONS%C3%84URE%2C+verschiedene+KETTENL%C3%84NGE_20_.jpg Tränenersatzmittel - DETAILS Hyaluronsäure mit höherer Kettenlänge (längere Moleküle, links) ist dickflüssiger und bildet typischerweise einen stabileren Film auf dem Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db5d66f118b996830fbf147/1580155466648/OSCB-Berlin.org_Hyalurons%C3%A4ure%2C+VISKOELASTIZIT%C3%84T+-+Nicht+Newtonsche+Eigenschaft_20_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db714cce1b2db2f02a4cbcc/1580155466637/OSCB-Berlin.org%2C+%28c%29+ENK_DIFFERENT+Components+can+be+MIXED+in+a+Tear+Supplements+for+Dry+Eye_20_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db6a98d628b613d41a62e41/1580155466654/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_.jpg Tränenersatzmittel - DETAILS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d847f112694431a6b4bfd35/1580155466627/OSCB-Berlin.org_THERAPIE%2C+Tr%C3%A4nenersatzmittel+DETAILS+%2B++MOLEK%C3%9CLE+-Tropfen+auf+Trockenes+Auge+-+FREI+2_.jpg Tränenersatzmittel - DETAILS https://oscb-berlin.org/trfe-pflanzlichhomopathisch daily 0.75 2019-06-13 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca51236c4c39c000133910b/1560413615381/Omni_Herba-Vision+Augentrost+sine+EDO_brennende-augen-herba-v-augentrost-sine-pckg-sdu-neu_d02a5176a7.jpg Omni Pflanzlich-Homöopathisch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca514d71905f4075fdea91e/1560413678541/Omni_Heidelbeere-BLAUbeere+%28Vaccinium+myrtillus%29_MK_brennende-augen-herba-vision-blaubeere_13410145c0.jpg Omni Pflanzlich-Homöopathisch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca51786ec212d355041f1cb/1560413713500/Omni_brennende-augen-herba-augenbad-plus-wanne-neu_MK_6f50ff2565.jpg Omni Pflanzlich-Homöopathisch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca50e5dec212d7162228d75/1555136246936/OmniVision+HerbaVision_BANNER.jpg Omni Pflanzlich-Homöopathisch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca516148165f55b94e5bb2c/1560413697349/Omni_Kamille+%28Chamomilla%29+und+Malve+%28Malva+sylvestris+L.%29_MK_brennende-augen-herba-kamille-plus_4142eb5c73.jpg Omni Pflanzlich-Homöopathisch https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5ca50eee9140b7bfee8fd80a/1560413594175/Omni_Herba_Vision_Augentrost_MD_sine_rgb_01f1de8d2b.jpg Omni Pflanzlich-Homöopathisch https://oscb-berlin.org/lidentzndung-blepharitis-demodex-milben daily 0.75 2021-04-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e41463d4b6b8940eedaa88d/1606746298376/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5_.gif Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis Die harmlosen normalen Demodex Haar Milben halten sich im Haarfollikel der Augenwimpern auf, wo sie sich auch vermehren Sie sind beweglich und können an den Wimpern entlang gleiten. Ihre Reste bilden typische zylindrische Schuppen an der Basis der Wimpern. Bei chronischer Lidentzündung (Blepharitis) ist die Anzahl von Demodex erhöht (überschiessendes Wachstum). > hier finden Sie ein mikoskopisches Bild von Demodex Milben https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2832bbcbf4145143954a1d/1605986116924/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+mit+Pinzette%2BDrehen_20_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis Wenn die Wimpern mit einer Pinzette gegen die Wuchsrichtung umgebogen werden, sind Demodex Haarmilben oft besser zu sehen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e284bab00949e3e2547d2da/1606814932741/LIDENTZ%C3%9CNDUNG+BLEPHARITIS+f%C3%BCr+LINK+Bilchen_10-72+%2B+Text_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis Chronische Blepharitis ist typischerweise eine lange bestehende Erkrankung mit geröteten und leicht geschwollenen Lidrändern, die oft wenig Beschwerden verursacht - Es ist wichtig, andere akutere und schwerere Erkrankungen auszuschliessen - deshalb sollte immer ein Augenarzt konsultiert werden ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e28451d06f0a742d337ef86/1580155631715/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+REINIGUNGSMITTEL%2C+Teebaum-Schaum+%2B+T%C3%BCcher_20_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc3c8353485235c863a21ca/1606666956244/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Lid-Hygiene%2B%26%2BLid-Care%2BProducts_BANNER_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis => Direkt zu Augenlid Hygiene und Lidpflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb904d98aa7f2271d6e27a5/1606667026932/DEMODEX-Therapie_30%2BLink%2BBildchen_2_+%281%29.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis => Direkt zu Therapie Optionen gegen DEMODEX Milben https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a2ecbf3730241dff42f99/1616950604176/DEMODEX-Therapie_10+Link+Bildchen__.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis => Einige Therapie-Optionen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb94da15ec8a10597564496/1606752487331/Thea_DEMODEX_FOTOS+Demodex+im+Mikroskop+%2B+Wimpern+in+Spaltlampe_hoch+%2B+Text_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis Demodex Milben auf einem Glas-Objektträger im Spaltlampenmikroskop (Abb. oben)- sie leben im Haarfollikel der Wimpern. Ihre Reste bilden oft typische zylindrische Ablagerungen (Kollaretten, Abb. unten) um die Basis der Wimpern. Abbildungen mit freundlicher Genehmigung von Laboratoires Théa https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2832eccbf41451439551c9/1580155631712/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+mit+Pinzette%2BRausziehen_20_.jpg Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis Nach Herausziehen einer Wimper hängen typischerweise Demodex Milben aus dem Haarbalg daran und können an der Spaltlampe diagnostiziert werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4146112c1d2d736858b72f/1581336084564/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5_HALB-BANNER_.gif Behandlung von DEMODEX Milben bei chronischer Lidentzündung / Blepharitis https://oscb-berlin.org/trfe-homopathischsimilasan daily 0.75 2019-11-27 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb37240b208fc58ff6a83ee/1560414305432/SIMILASAN_ENTZ%C3%9CNDETE+Augen+Tropfen_D.jpg Similasan - Homöopathische Augentropfen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb36f526e9a7f1034a77733/1560414231488/SIMILASAN_%C3%9CBERANSTRENGTE+Augen+Tropfen_D.jpg Similasan - Homöopathische Augentropfen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb225700d929797d53219ec/1560414151072/Gruppe_TROCKENEAugen_D.jpg.2018-04-13-08-46-10.jpg Similasan - Homöopathische Augentropfen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb17f70f9619adc67e5d346/1555248108481/SIMILASAN_LOGO+auf+BILD_30_.jpg Similasan - Homöopathische Augentropfen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb31eeda4222f2c69e510e8/1555248108498/SIMILASAN_Kombi_TaschenAPOTHEKE_de.jpg.2018-04-13-08-45-51.jpg Similasan - Homöopathische Augentropfen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb228d871c10b4ea8c8d9e2/1560414188839/SIMILASAN_Gruppe_AllergischeAugen_D.jpg.2018-04-13-08-46-11.jpg Similasan - Homöopathische Augentropfen https://oscb-berlin.org/trfe-pflanzlich-similasan daily 0.75 2019-06-13 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb333ec104c7b72bcd47594/1560413810990/SIMILASAN_LOGO+auf+BILD_30_.jpg Similasan - TrFE - Pflanzlich https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cb3356bfa0d60178b20d557/1555249235276/Similasan+Optiminic_Tr%C3%A4nenErsatzMittel+mit+Hyalurons%C3%A4ure+und+EUPHRASIA++%2B++EDO_.jpg Similasan - TrFE - Pflanzlich https://oscb-berlin.org/kontaktlinsen- daily 0.75 2020-08-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3c2c9573ac32273e01a9ad/1597779110405/OSCB-Berlin.org_Kontaktlinse+auf+Finger+FRAGEZEICHEN_.jpg Kontaktlinsen - Fragen & Antworten https://oscb-berlin.org/dueberblick-ueber-kontaktlinsen daily 0.75 2020-11-25 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709a2/1556970457336/OSCB-Berlin.org_HYGIENE-ist-ein-ENTSCHEIDENDER-FAKTOR-beim-KONTAKTLINSEN-TRAGEN_.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770954/1597758479127/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_OPTISCHE-VORTEILE-der-Kontaktlinse_LINK-Bildchen.gif D-UEBERBLICK über ... KONTAKTLINSEN - Optische Vorteile https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770959/1597758488390/KURZ+17-8fps_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%28in+PSD+60cm-72dpi%2C17%29+GIF+8fps.gif D-UEBERBLICK über ... KONTAKTLINSEN - Kontaktlinsen SCHWIMMEN im Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770965/1597758548574/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen+TAGEStragelinsen%2C+Wegwerf+Kontaktlinsen%2C+Disposable+Contact+Lenses_10+LINK+BILDCHEN_.jpg D-UEBERBLICK über ... KONTAKTLINSEN - Tages Linsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770957/1597758712214/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KOSMETIK%C2%A0und-%C3%84STHETIK-beim-Kontaktlinsen-Tragen_LINK-Bildchen.gif D-UEBERBLICK über ... KONTAKTLINSEN - Kosmetik und Ästhetik https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770963/1597758494589/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Kontaktlinsen+ANPASSUNG_10+LINK+BILDCHEN_.jpg D-UEBERBLICK über ... KONTAKTLINSEN - Kontaktlinsen Anpassung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc77095b/1597758510214/OSCB-Berlin.org_TYPEN-von-KONTAKTLINSEN-auf-der-Augenoberfl%C3%A4che_20_.gif D-UEBERBLICK über ... KONTAKTLINSEN - Typen und Material von Kontaktlinsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc77095f/1597758580610/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif D-UEBERBLICK über ... KONTAKTLINSEN - Medizinische Kontaktlinsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc770961/1597758560676/OSCB-Berlin.org_Sklerale-Kontaktlinsen-reichen-bis-weit-in-den-Fornix_10+LINK+BULDCHEN_.gif D-UEBERBLICK über ... KONTAKTLINSEN - Sklerale Kontaktlinsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5cd1b7a7104c7b9bdc770953/5cd1b7a7104c7b9bdc77095d/1597758537038/OSCB-Berlin.org_HYGIENE-ist-ein-ENTSCHEIDENDER-FAKTOR-beim-KONTAKTLINSEN-TRAGEN_20_.gif D-UEBERBLICK über ... KONTAKTLINSEN - HYGIENE ist ein entscheidender Faktor https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1c1a9419202f2bcebf5a9/1557250481056/OSCB-Berlin.org_PARAMETER-zur-KONTAKTLINSEN-Anpassung-%28Kr%C3%BCmmungs-RADIUS-und-Gr%C3%B6ssen-DURCHMESSER%29.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f3bdd3bfd46d27dcf6f9bf9/1597758794680/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KOSMETIK%C2%A0und-%C3%84STHETIK-beim-Kontaktlinsen-Tragen_LINK-Bildchen.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770998/1556970400624/OSCB-Berlin.org_SKERALE-KONTAKTLINSE-auf-dem-Auge%2C-Foto-von-der-Seite-%28FOTO-von-keratoconusinfo.wordpress.com%29.gif D-UEBERBLICK über ... KONTAKTLINSEN SKLERALE KONTAKTLINSE. Grosse Kontaktlinsen, die weit über die Hornhaut und auch den Limbus hinausragen werden als Sklerallinsen bezeichnet, da sie auf der bulbären Konjunktiva über der festen weisslichen Augenhaut (Sklera) aufsitzen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709b4/1556970546164/GIF-ANIMATION_ORTHOKERATOLOGY-Contact-Lens_450-27-1_.gif D-UEBERBLICK über ... KONTAKTLINSEN Eine schematische Animation zeigt, wie die Anpassung einer ORTHOKERATOLOGIE Kontaktlinse mit (etwas) anderer Form als die Honhaut die Form der Honhautepithels zunehmend verändert. Hier wird das Hornhautepithel durch das Tragen einer flacheren Kontaktlinse zunehmend abgeflacht - Dadurch verringert sich Lichtbrechung, wie es für einen kurzsichtigen Patienten notwendig wäre (Näheres dazu in der nächsten Abbildung). Nach Absetzen der Kontaktlinse bildet sich die natürliche Form der Hornhaut langsam wieder zurück. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709b2/1500404783701/ D-UEBERBLICK über ... KONTAKTLINSEN Stark vereinfachte schematische Darstellung der Wirkung von ORTHOKERATOLOGIE-KONTAKTLINSEN auf die FORM der Hornhaut/ Kornea - die Grösse des Hornhaut-Epithels ist aus didaktischen Gründen übertrieben) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770976/1500388700442/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770992/1500135555744/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709a4/1556970467006/OSCB-Berliin.org_INFEKT%C3%96SE-KOMPLIKATIONEN-beim-KONTAKTLINSEN-TRAGEN-%28Fotos%3B-FLORENCE-MALET%29.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770990/1500465209076/OSCB-Berlin.org_Parameter-zur-KONTAKTLINSEN-Anpassung-KONTAKTLINSEN-RADIUS---ZU-Flach-%2B-ZU-Steil_.gif D-UEBERBLICK über ... KONTAKTLINSEN Wenn der Krümmungsradius einer Kontaktlinse zu stark von der Krümmung der Hornhaut abweicht ist der Sitz der Linse gestört ... und stört seinerseits das Gewebe. Eine zu flache Kontaktlinse kann typischerweise zu einen Druck auf die Mitte der Hornhaut (Abb. links) führen, während bei einer zu steilen Linse der Rand der Kontaktlinse Druck auf das unterliegende Gewebe ausübt und sich eindrücken kann (Abb. mitte). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709a6/1556970481018/27-TAGES-KONTAKTLINSEN-im-KONJUNKTIVALSACK_2017-BMJ-Publishing-Group%2C-www.bmj.com-content-358-bmj_OPT-WEB.gif D-UEBERBLICK über ... KONTAKTLINSEN Abbildung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77097a/1500478654449/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709ae/1500394303297/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770986/1556970309490/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_KOSMETISCHE-Kontaktlinse-mit-aufgedruckter-Iris-Farbe_2.png D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770988/1499430873990/ D-UEBERBLICK über ... KONTAKTLINSEN Eine weiche korneosklerale Kontaktlinse schwimmt im Tränenfilm und wird durch den Lidschlag bewegt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77097c/1556970253004/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709b8/1556970581283/ D-UEBERBLICK über ... KONTAKTLINSEN Viele interessante Ideen für die ZUKUNFT des Kontaktlinsentragens kursieren und befinden sich teilweise in der Entwicklung- Einige davon sind hier dargestellt(VON: lifeboat.com blog 2016 03 fish-and-insects-guide-design-for-future-contact-lenses - Posted by Klaus Baldauf) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77098e/1556970357343/OSCB-Berlin.org_PARAMETER-zur-KONTAKTLINSEN-Anpassung.gif D-UEBERBLICK über ... KONTAKTLINSEN Die beiden wesentlichen Parameter bei der Anpassung einer Kontaktlinse sind der Krümmungsradius (links, gestrichelt ist der Krümmungsradius der Hornhaut selbst angegeben) und der Grössendurchmesser (rechts). Je grösser der Durchmesser ist, desto mehr von der Oberfläche des Augapfels wird überdeckt von der Kontaktlinse. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709aa/1499439111673/ D-UEBERBLICK über ... KONTAKTLINSEN SKLERALE KONTAKTLINSEN dienen primär zum Schutz einer gestörten, verletzten oder anderweitig erkrankten Augenoberfläche und bewegen sich daher auch beim Lidschlag nur wenig. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709ac/1499442179040/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709b6/1500457246143/ D-UEBERBLICK über ... KONTAKTLINSEN Die Wirkung von ORTHOKERATOLOGIE-Kontaktlinsen auf die Form der Hornhaut (grüner Pfeil) und auf die resultierende Lichtbrechung ist in dieser stark vereinfachten Zeichnung dargestellt. (Die Grösse des Hornhaut/ Kornea-Epithels, relativ zum Rest des Auges, ist aus didaktischen Gründen stark übertrieben - siehe auch die Abbildung darüber) Dargestellt ist ein kurzsichtiger/ myoper Patient bei dem die Lichtstrahlen schon vor der Netzhaut vereinigt werden. Nach Abplattung der Hornhaut(grüner Pfeil) durch eine Ortho-K Kontaktlinse entsteht eine zerstreuende Wirkung und die Vereinigung der Lichtstrahlen erfolgt dann erst auf der Netzhaut - was zu einem scharfen Bild führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770994/1500465575218/ D-UEBERBLICK über ... KONTAKTLINSEN Schematische Animation des Verhaltens einer Kontaktlinse auf dem Auge (hier eine weiche Hydrogellinse) bei Augenbewegungen und Lidschlag. Der Rand der Kontaktlinse stellt dabei typischerweise das grösste Hindernis dar. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770996/1499425240987/ D-UEBERBLICK über ... KONTAKTLINSEN Kontaktlinsen werden nach der Größe unterschieden und bezeichnet nach den Organen oder Zonen der Augenoberfläche benannt auf denen sie liegen als korneale, korneosklerale oder sklerale Kontaktlinsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709a0/1556970447064/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_MIKROBEN-auf-Kontaktlinsen-k%C3%B6nnen-sich-verstecken-in-protektiven-BIOFILMEN.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77097e/1556970266210/OSCB-Berlin.org_Kontaktlinsen-sitzen-mitten-in-der-Funktionseinheit-der-Augenoberfl%C3%A4che-2-%28Fade%29.gif D-UEBERBLICK über ... KONTAKTLINSEN Kontaktlinsen können die Brechkraft dort korrigieren, wo auch der Hauptteil der natürlichen Brechkraft erzeugt wird - an der Vorderseite der Hornhaut https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770980/1597777002042/ D-UEBERBLICK über ... KONTAKTLINSEN KONTAKTLINSEN befinden sich mitten in der Funktionseinheit der Augenoberfläche und stehen damit in ´Berührung´ allen Komponenten der Augenoberfläche - vom Tränenfilm bis zu den Geweben - was Vor- und Nachteile haben kann. Hier ist eine mittelgrosse weiche korneosklerale Kontaktlinse dargestellt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77099a/1556970410657/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_HARD+vs.+SOFT+Contact+Lenses%2C+WEICHE+Flexible+Hydrogel++VS.++HARTE+Kontaktlinsen+auf+FINGER+_20_.jpg D-UEBERBLICK über ... KONTAKTLINSEN WEICHE/ Flexible (rechts) und HARTE/ Formstabile Kontaktlinsen im Vergleich https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770923/1483800235627/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77098a/1556970334539/ D-UEBERBLICK über ... KONTAKTLINSEN Eine Region in der eine Kontaktlinse auf dem Auge besonders deutlich wahrgenommen werden kann vom Träger ist der Lidrand. Dieser muss beim Lidschlag immer über den Rand der Linse hinweg gleiten was ein Fremdkörpergefühl auslösen kann https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770982/1556970288413/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_OPTISCHE-VORTEILE-der-Kontaktlinse.gif D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709a8/1499966410225/ D-UEBERBLICK über ... KONTAKTLINSEN SKLERALE KONTAKTLINSEN bieten einen SCHUTZ der Augenoberfläche in vielen Aspekten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc7709b0/1500453246110/ D-UEBERBLICK über ... KONTAKTLINSEN Hier das Foto (rechts) eines Patienten mit pathologischer Hornhautvorwölbung (Keratokonus), der auf einer Internetseite über seine positiven Erfahrungen mit Skleralen Kontaktlinsen bei dieser Erkrankung berichtet. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77099e/1499438668086/ D-UEBERBLICK über ... KONTAKTLINSEN Eine kleine harte/formstabile korneale Kontaktlinse auf dem Auge. Sie wird beim Lidschlag bewegt und zentriert sich danach wieder selbst. Diese Linsen haben eine sehr hohe Sauerstoffdurchlässigkeit, gute Beweglichkeit und eine relativ gute Langzeitverträglichkeit für das Augengewebe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77098c/1556970347562/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_Vorwachsen-%28Neovaskularisation%29-des-Limbalen-Randschlingen-Netzes-auf-die-Kornea.gif D-UEBERBLICK über ... KONTAKTLINSEN Bei Sauerstoff-Mangel der Hornhaut beginnen die Gefässe vom Rand der Hornhaut zur Mitte vozuwachsen - was leider nicht rückgängig zu machen ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770978/1500390517177/ D-UEBERBLICK über ... KONTAKTLINSEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc77099c/1556970423096/ D-UEBERBLICK über ... KONTAKTLINSEN Eine kleine harte/formstabile korneale Kontaktlinse auf dem Auge - seitliche Ansicht. Diese Linsen haben typischerweise einen deutlich kleineren Durchmesser als die Hornhaut auf der sie schwimmen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd1b7a7104c7b9bdc770921/1483360052525/OSCB-GIF_KL+Weich_OSCB%2BTEXT_LIDER+%28FRONTAL%29+ANIMATION+BLINZELN_+%2B+KONTAKTLINSE+WEICHE+Corneoscleral+FESTER+%2880cm-72dpi%29+18-8fps+GIF.gif D-UEBERBLICK über ... KONTAKTLINSEN https://oscb-berlin.org/trfe-zusatz-visufarm-visuxl daily 0.75 2019-06-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd95180f1d9430001570937/1559751748290/VisuFarma_VisuXL%2C+Q10+im+Hyalurons%C3%A4ure+Netzwerk%2C+Schema_30_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd94f336e9a7f57d780ada6/1559751761194/VisuFarma_VisuXL%2C+Hyalurons%C3%A4ure+Netzwerk%2C+Schema_30_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7cdbb6c9de600015f0212/1559818058708/VisuFarm%2C+NAVIBLEFMonodose+Teebaum%C3%96L+Wischt%C3%BCcher+bei+DEMODEX_0219-270x247.png VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cd94ae715fcc07f1e297e5d/1559741011272/VISUXL10ml-DE-FR-560x575.png VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdc67ace2c48347398642aa/1559743153987/Xailin+GEL.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdd40cbeb39314f06e444fa/1559818020862/VisuFarm_Naviblef+DAILY+CARE_PACK+%2B+FLASCHE+%28Ital%29_OPT_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7eb80d12ad70001208e92/1565718138239/VisuFarm%2C+VISU+XL%2C+MOVIE+Symbolbild_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7da920a25320001d95473/1559747260755/VisuFarma+Naviblef_Patienten+Broch%C3%BCre+WAS+IST+DEMODEX+mit+Zeichnung_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdd408161278900014995a6/1559817990359/VisuFarm_Naviblef+INTENSIVE+CARE_PACK+%2B+FLASCHE+%28Ital%29_OPT_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7c161095f4e0001e19739/1559740784543/VisuFarma_BANNER+%2B+LOGO_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cda74c44e17b650ce7441eb/1565719301626/Xailin+HA+Pack+mit+Flasche.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdc6c99f9619a063a5d4ef2/1565719986303/Xailin+Night+PACK+mit+TUBE.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdd4257ee6eb05a8b673c46/1558004321957/VisuFarm_NAVIBLEF_ANWENDUNGSHINWEiSE_30_.jpg VisuFarm-Zusatz-VisuXL https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7e3eeaf70050001aa92fc/1559751821788/VisuFarm%2C+VISU+XL%2C+EDO+aus+FOTO_20_.jpg VisuFarm-Zusatz-VisuXL https://oscb-berlin.org/trfe-santen-cationorm-biolan daily 0.75 2019-11-18 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cddb0d8d7e008000151ee48/1559756743584/Santen_CATIONORM%2C+Flasche+und+EDO+%2B+PACK.jpg Santen-Cationorm-Biolan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cf7fee07e57b400019c55d7/1559756524052/CATIONORM%2C+NANO+DROPLET%2C+SCHEMAZEICHNUNG_Figure_2_Novasorb_Cationic_Nanoemulsions.jpg Santen-Cationorm-Biolan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cddb68ff22c58000161b1fb/1559753468854/Santen_BIOLAN+EDO+AugenTROPFEN+0%2C15%25_PACK%2BEDO.jpg Santen-Cationorm-Biolan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cddb92e40e69c0001e29a3b/1559753496665/Santen_BIOLAN+GEL+0%2C3%25_PACK_20_.jpg Santen-Cationorm-Biolan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cddaa2fcc47570001c809f4/1559753405897/Augenoberfl%C3%A4che+mit+CATIONORM+Spritzern.jpg Santen-Cationorm-Biolan https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cde60c4dc68af0001ff422d/1558077722565/Santen+LOGO%2C+Kombiniert_3_.jpg Santen-Cationorm-Biolan https://oscb-berlin.org/verschreibungspflichtige-arzneimittel daily 0.75 2021-07-11 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5cdebebdfdd75f00012c476c/1569317114484/Verschreibungspflichtige+ARZNEIMITTEL_30+H1%2C5_2_.jpg Verschreibungspflichtige Arzneimittel https://oscb-berlin.org/kongresse daily 0.75 2019-12-13 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d0f9795b3f1e700014d9041/1561302947876/Kongressorganisation+GERLING_LOGO+Bild+BANNER+2_30_.jpg Kongresse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d1262e3ac5c3700017c5567/1561486063004/VKKA+LOGO+%28Vereinigung+Kontaktlinsen+Anpassender+Augen%C3%A4rzte%2C+%C3%96sterreich%29.jpg Kongresse https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d12625dfba9fe0001e57c4a/1561485999687/VKKA+LOGO+%28Vereinigung+Kontaktlinsen+Anpassender+Augen%C3%A4rzte%2C+%C3%96sterreich%29.jpg Kongresse https://oscb-berlin.org/downloads daily 0.75 2019-12-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8c95826e155e1916cb0114/1569507973168/Therapeutischer+Stufenplan%2C+SEITE+aus+ZPA+3-2019_10+LINK+BILDCHEN_.jpg Nützliches Arbeitsmaterial https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5d8c73914b1bc70967f37118/1575656047519/OSCB-LOGO+%26+LINK_%28www.OSCB-Berlin.org%29_.jpg Nützliches Arbeitsmaterial https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dea96cae711c857b992b370/1575655223656/SPEED+SCHNELLTEST+%2817%29_Link+Bildchen_.jpg Nützliches Arbeitsmaterial https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5db0127c91ea786aad976682/1571820166072/Modifizierter+SPEED+Test_10%2C+LINK+BILDCHEN_.jpg Nützliches Arbeitsmaterial https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dd2dfc92e1e1821e327a9b9/1574101016557/OSCB-Berlin.org+-+Verwendung+nur+nach+Vereinbarung_TROCKENES+AUGE+-+PRAKTISCHE+TIPS+F%C3%9CR+DIE+PATIENTEN-INFORMATION_10-72_.jpg Nützliches Arbeitsmaterial https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dea75e4c2468953b67a8d63/1575646722877/Physikalische+Therapie+9_LINK+Bildchen_.jpg Nützliches Arbeitsmaterial https://oscb-berlin.org/thea-trfe daily 0.75 2019-11-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4612fd5ccf627e18a0137/1571053878506/THEA+LOGO+%2B+BANNER%2C+Foto+Frau+mit+Augen+Tropfen_.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da48afaec22576e9e11274e/1571064581924/Thealoz_Duo_GEL_30er+%28Pack+EDO+DE%29_UD.jpg Tränenersatzmittel Dünnflüssig Erhältlich als Packung mit 30 Einzeldosisbehältnissen (EDO/ Uni-Dose). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da463cdf30aa078096fd45d/1571054550386/Thea_Hyabak_ABAK+Steril-Dispenser+System.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4999f1a387e45075ccc44/1571068328329/Thea+Liquigel+%28Pack%2C+EDO+DE%29_ud.jpg Tränenersatzmittel Dünnflüssig Liquigel als unkonservierte Einzeldosisbehältnisse (EDO, 30 x 0,5 g) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da462e3f30aa078096fc6bf/1573913003241/Thea+HYABACK+PAck+%28DE%29+1er_3er_hyabak.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4833aa4f8276372b3a168/1571062601095/ThealozDuo-%28Pack+Flaschen+DE%29+3x10_30xUD.jpg Tränenersatzmittel Dünnflüssig Auch in der preisgünstigen Großpackung mit 3 Tropfflaschen und als Uni-Dose-Packung mit 30 Einzeldosisbehältnissen erhältlich https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4814a90f95552c6b8bd52/1571062386478/Thealoz+Duo+-+Name-Logo.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4821a765b1526483089e8/1571062308584/Thea+Hyabak%2C+NAme-Logo.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da498b90e28a278c87f32e3/1571068106054/Thea+LIQUIGEL%2C+Name-Logo.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da489571cec496de62796f8/1574520468613/Thea+ThealozDuo_Abak-0317.jpg Tränenersatzmittel Dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da48a7d4bdda00b222ac2c1/1571064453548/Thealoz+Duo+GEL%2C+Name-Logo.jpg Tränenersatzmittel Dünnflüssig https://oscb-berlin.org/lid-hygiene-care-thea daily 0.75 2019-10-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4c967bdb9bc0dc897ead1/1571080592374/BLEPHACLEAN+blephaclean+%28Pack+DE%29_n.png Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4d0ef8f4a471cbd82b051/1571082485896/Thea+BLEPHASOL+Duo+PAck+%2B+Flasche+%28DE%29_n.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4ce9871c4b524075972a8/1571081890288/Thea+BLEPHAGEL+Duo+%28Pack+%2B+Tube+DE%29+_n.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4c1ca38355036c0d806c5/1571078610050/Blephasteam%2C+Name%2BLogo_.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4c52cd6ec206e920f37f4/1571079482608/THEA+BlephaDEMODEX+Reinigungst%C3%BCcher+mit+Teebaum-Auszug+2.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4d0cc62d35c3808be830d/1571082457636/Thea+BlephaSOL+Duo+%28Name+%2B+Logo+DE%29.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4b7e3b9a77e22d118498a/1571076143339/THEA+LOGO+%2B+BANNER+mit+Henry+u.+Jean-Fred+Chibret_.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4caa6e0d4c84c4751af5e/1571080876973/BLEPHACLEAN+Name%2BLogo_jpg.jpg Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4c2528ab87e400ee6320c/1571078752989/BLEPHASTEAM%2C+Pack+%2B+Brille+%28DE%29_n.png Lid-Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da4cdca2ec2ba6adbb3936d/1571081683718/BlephaGEL+Duo+%28Name%2BLOGO%29.jpg Lid-Hygiene & Pflege https://oscb-berlin.org/lidcare daily 0.75 2021-03-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da6fa7d45908c2a5e4c4390/1606578742049/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye+Disease%2C+Trockenes+Auge_Meibomdr%C3%BCsen+Dysfunktion+%28MDD%2C+MGD%29+mit+verstopften+und+irregul%C3%A4ren+%C3%96ffnungen+eingedicktes+Sekret+wird+ausgepresst_20_.jpg AUGENLID - Hygiene & Pflege Verstopfung der Meibomdrüsen Öffnungen. Eingedicktes Öl in der Drüse kann die Öffnung leicht ausstülpen (´pointing´, weissliche Punkte im oberen Bild) oder es kann aus den Öffnungen herausquellen auf den Lidrand (unteres Bild). Eine Drüsenverstopfung kann allerdings auch unauffällig aussehen ohne weitere Untersuchungen - dies wird als NOMGD bezeichnet https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da75dbcf4c5696a54a40e2b/1578772234286/OSCB-Berlin.org%2C+%28c%29+ENK_Lid-Hygiene+%26+Lid-Care+Products_BANNER_.jpg AUGENLID - Hygiene & Pflege => gleich zur Produkt-Auswahl https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1f68c58bb6ff63f6083d6a/1580155538572/OSCB-Berlin.org_%28c%29+ENK_LIDRAND+287+gedr-li_.jpg AUGENLID - Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da703c83aaf2b7990a64dd6/1578771495836/www.OSCB-Berlin.org_ABLAGERUNGEN+und+VERKRUSTUNGEN+auf+dem+Lidrand+bei+Meibomdr%C3%BCsen+St%C3%B6rung%2C+MDD%2C+MGD+und+BLEPHARITIS+2_20_.jpg AUGENLID - Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5da7061d969104796c3464e5/1606415627731/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_.gif AUGENLID - Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeaafaeaf37e3b64794fdb/1606841057378/LIDRAND+Foto+IMG_0287+RET_MON+mit+ABLAGERUNGEN+an+WIMPERN%2C+ev.+DEMODEX+2+%2BFREIER+Lidrandschmutz+heller_20_.jpg AUGENLID - Hygiene & Pflege Lidrand mit Ablagerungen und Verkrustungen auf dem freien Rand und an den Wimpern. Ablagerungen von klebrigem Material kleben oft Wimpern zusammen zu Büscheln. Eine animierte Abbildung zeigt, wie die Ablagerungen sich auf dem Lidrand bilden bei verschiedenen Störungen des Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1a262551f223209a14fd66/1606580470147/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Lid-Hygiene%2B%26%2BLid-Care%2BProducts_BANNER_+%281%29.jpg AUGENLID - Hygiene & Pflege https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f492367d9079977394d37ad/1606331266865/OSCB-Berlin.org_%28c%29ENK_Der+LIDRAND+-+The+LID+MARGIN_ohne+Text+2_20_.jpg AUGENLID - Hygiene & Pflege Der Lidrand reicht von der äusseren Kante mit den Wimpern über den freien Lidrand (… dort wo der Kajalstift aufgetragen werden kann) bis zur inneren Kante, die auf dem Augapfel liegt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbf78aca97599144ef0fc58/1606383792100/LIDRAND+Foto+20200114125329_IMG_0287+RET_30_.jpg AUGENLID - Hygiene & Pflege https://oscb-berlin.org/lidhygiene-optima daily 0.75 2019-12-11 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5daca0f0c8d49d796dfbe0db/1571594510042/Optima%2C+BLEPHACURA+SALINA+Pack_.jpg Optima-Lidhygiene https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dac9fde611aac6dfa8eee54/1571594237323/Optima%2C+BLEPHACURA+Pads+Pack_.jpg Optima-Lidhygiene https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dac9210c8d49d796dfa99f2/1571590707531/Optima%2C+BLEPHACURA+Flasche+Pack_.jpg Optima-Lidhygiene https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5daca68a218aa17443b9c41c/1571595934662/Optima_Blephacura%2C+EyeDoctor+STOFF-MASKE.jpg Optima-Lidhygiene https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5daca561bcfe0c53d05b7301/1571595644886/Optima_Blephacura%2C+GelMASKE.jpg Optima-Lidhygiene https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dee90785e5ce97f94069284/1575915644290/LidhygienePflege_Blephacura+Optima_BANNER+OHNE+Logo+60_.jpg Optima-Lidhygiene https://oscb-berlin.org/iluxalcon daily 0.75 2019-11-15 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dc9bf5436ffb63f22038bfb/1573502817972/iLux-cloudy-meibum+3_TearFilmInnovations_ALCON_.png Alcon-Ilus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dc9a772e2393045507e945a/1573496736070/ALCON+INNOVATION_Banner_.jpg Alcon-Ilus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dc9a8cc9b065c7fec041054/1573497052571/iLux-with-annotation2-1__TearFilmInnovations_ALCON_300dpi+%2B+Neue+Texte+ALS+JPG_.jpg Alcon-Ilus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dc9afa3038169207276c49b/1573498808706/iLux-Treatment-2+Expression_TearFilmInnovations_ALCON_.png Alcon-Ilus https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5dc9ad9051bb2a4a74a3f858/1573498284347/iLux-Treatment-Heating-1_TearFilmInnovations_ALCON_.png Alcon-Ilus https://oscb-berlin.org/similasan-l daily 0.75 2019-11-27 https://oscb-berlin.org/d-therapy-options-in-dry-eye-disease-1-1 daily 0.75 2020-08-24 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2ade8/1487611876096/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adbf/1491475304043/ d-THERAPIE 3 - TRÄNENERSATZ ... zwei Seiten derselben Medaille zeigen, dass das Management von Tränen bzw. deren Mangel an der Augenoberfläche in verschiedene Schritte unterteilt werden kann: (1) Die Stimulierung des natürlichen Tränenflusses durch Sekretagogen, (2) die Ergänzung von Tränenkomponenten entweder als einzelne Komponenten wie z. B. nur Lipide oder als eine Art Komplettlösung wie " Künstliche Tränen " und (3) die RETENTIONSZEIT der Tränenflüssigkeit an der Bulbar-Oberfläche, bevor sie verschwinden und in die Tränendrainage abfließen System ... das ebenfalls Teil der Augenoberfläche ist, aber die Hornhaut und die Bindehaut nicht mehr halten kann . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2ada7/1488631647650/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adca/1486921274067/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adf4/1494866042677/ d-THERAPIE 3 - TRÄNENERSATZ Sekretionszellen mehrerer Augenoberflächengewebe , wie hier in einer schematischen Zeichnung gezeigt, sind mit Zellmembranrezeptoren für den Agonisten P2Y2 ausgestattet , die eine Regulation der Sekretion ermöglichen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2add6/1491502328036/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adb9/1491480079876/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adcd/1486993311900/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adf1/1491412496749/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adb0/1488478065674/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2add0/1486988647388/ d-THERAPIE 3 - TRÄNENERSATZ Mit zunehmender Zerstörung von Geweben und Regulationssystemen bei mittelschweren bis schweren Erkrankungen des trockenen Auges neigen die primären Arten von Tränenfilmmangel dazu, sich zu vermischen, da die Augenoberfläche zunehmend dysreguliert wird. Ein Hauptkonzept für einen Mangel an wässrigen Tränen basiert auf einer solchen Dysregulation, die auftritt, wenn die afferente sensorische Innervation an der eigentlichen Augenoberfläche, der Hornhaut und der Bindehaut beeinträchtigt ist und somit der neurale Reflexbogen für die Tränensekretion verändert wird, was zu einer geringeren wässrigen Sekretion führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adb6/1491476583903/OSCB-Bild_6_Dry+Eye+Disease_The+HIERARCHY+of+PATHOGENETIC+FACTORS+-+MAIN+CAUSATIVE+FACTORS+%28auf+gelbem+ZETTEL%29_NEU.png d-THERAPIE 3 - TRÄNENERSATZ Die B ASIC-URSACHENFAKTOREN für trockene Augenkrankheiten sind ein Mangel an Tränensekretion und / oder Tränenfilmbildung, da dies die Augenoberfläche überall und jederzeit feucht hält und die perfekte Sehschärfe beeinträchtigt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adbc/1488559966527/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2ade5/1488624485798/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2add9/1491502319528/ d-THERAPIE 3 - TRÄNENERSATZ Im linken Bild sind einzelne Hyaluronsäuremoleküle (HA) mit vielen gebundenen Wassermolekülen zu sehen. Auf der rechten Seite ist das lose Bindegewebe der Conjunctival Lamina propria dargestellt - wobei HA als Abstandshalter zwischen den Kollagenfasern (grau) fungiert und HA dem Gewebe somit eine gewisse Elastizität verleiht. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adf7/1494865248360/OSCB-Berlin.org_P2Y2+Receptors+on+Ocular+SECRETORY+TISSUES+allow+to+target+Increased+Tear+Secretion+by+P2Y2+AGONISTS+%28Diquafosol%29.png d-THERAPIE 3 - TRÄNENERSATZ Sekretagogen, die den P2Y2-Rezeptor auf sekretorischen Augengeweben stimulieren, ermöglichen eine gezielte Sekretion von Tränenkomponenten und damit eine Zunahme des Tränenflüssigkeitsvolumens auf der Augenoberfläche. Ein Beispiel für diese Klasse von Tränenergänzungsmitteln ist der P2Y2-Agonist Diquafosol von Santen Pharma, der jedoch nur in Asien erhältlich ist. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adc4/1484571113270/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f43968dfd699801ae8272c3/1598265649470/OSCB-Berlin.org_Migration+of+Fluorescein-stained+Liposomal+Spray+over+the+Lid+Margin+onto+the+Ocular+Surface_.jpg d-THERAPIE 3 - TRÄNENERSATZ Klinische Fotos zeigen die Anwendung von Liposomenspray bei einem normalen Auge (Abb. I, vor der Anwendung). Liposomen, die zur besseren Erkennbarkeit mit einem grünen Fluoreszenzfarbstoff markiert sind, finden nach dem Aufsprühen auf das geschlossene Augenlid (offener Pfeil in Abb. II) von selbst ihren Weg über den Lidrand auf die Augenoberfläche und reichern sich im Tränenmeniskus an (Pfeile in Abb. III) zur Verteilung auf dem Tränenfilm. (Abbildungen mit freundl. Genehmigung von Prof. D. Dausch) . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adad/1486910432167/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2addc/1509536090165/Bild1OSCB-Berlin.org_Hyaluronic+Acid+%28HA%29+Non-Newtonian+Behaviour%2C+Open+Eye+vs.+Blinking.png d-THERAPIE 3 - TRÄNENERSATZ Hyaluronsäure hat Aspekte nicht-Newtonscher Fähigkeiten wie die natürlichen Tränen mit niedrigerer Viskosität während Augenzwinkern (Bilder mit freundlicher Genehmigung von TRB Chemedica) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adee/1487612792299/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2ade2/1494773305752/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adaa/1486910309616/ d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adc7/1486929632268/OSCB-GIF_LIDER+%28FRONTAL%29+Animation+%28ENK%29+BLINZELN_%28aus+KL+Weich%29_NEU+MAN.+Verschob_OHNE+OSCB_mit+LIPIDSPRAY+Vollformat_25-8fps_.gif d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adb3/1487609122116/ d-THERAPIE 3 - TRÄNENERSATZ Es gibt mindestens zwei Haupttypen von trockenem Auge, die beide zu einem geringen Tränenvolumen führen, jedoch einen unterschiedlichen pathophysiologischen Hintergrund und damit unterschiedliche therapeutische Ansätze haben. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2addf/1494773873788/OSCB-Berlin.org_Augenoberfl%C3%A4che_Ocular+Surface+for+HA+High+Viscosity+vs.+Low+Viscosity.png d-THERAPIE 3 - TRÄNENERSATZ https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2add3/1488625861454/OSCB-Bild_1_Tears+and+Tear+FilM_HYALURONIC+ACID+%28HA%29+is+a+Biopolymer+with+very+high+water+binding+capacity_Wasser+BLAU+%2B+3D.png d-THERAPIE 3 - TRÄNENERSATZ Hyaluronsäure (blau) ist ein großes Biopolymer mit sehr hoher Wasserbindungskapazität. Es tritt typischerweise zB im geleeartigen Glaskörper des Auges, in der viskosen Flüssigkeit der Gelenke und im Bindegewebe auf. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df739b40027c56344d2adeb/1487613740038/ d-THERAPIE 3 - TRÄNENERSATZ https://oscb-berlin.org/d-therapy-options-in-dry-eye-disease-1-1-1 daily 0.75 2019-12-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f134a/1486895523688/ d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f135c/1576483321665/ d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN Contact lens wear is a general stress factor for the Ocular Surface and Tear Film. CL e.g. increase the frictional forces during the normal eye movements and blinking. Therefore CL wear has higher requirements for tear volume and (lubricative) quality than required in non-CL-wearers. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f1350/1486896892826/ d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f1338/1576483321661/OSCB-Bild_6.0_Dry+Eye+Disease_THERAPY_DIETARY+APPROACHES+to+Dry+Eye+Prevention+and+Therapy.png d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN Important for sufficient moisture and health of the ocular surface are certain dietary facotrs such as https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f1356/1486899263613/OSCB-GIF_ANIMATION+BLINK+%28FRONTAL%29+%2BCL+Soft+17-8%2C+60-72_.gif d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f1344/1486894740501/ d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a0d34929a2cbf3f133e/1486898310860/ d-Tieferer Einblick THERAPIE 2 - RISIKOFAKTOREN https://oscb-berlin.org/d-therapy-options-in-dry-eye-disease-1-1-2-1 daily 0.75 2019-12-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28935/1487603595857/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28919/1487235630503/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28928/1484575482564/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28947/1502199391926/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie LID HYGIENE is typically done with some kind of disposable pad similar to those that are used for removing make-up. In addition some kind of liquid is applied from clean water to special lipid solutions - the use of detergents, however would likely disturb the tear film lipid layer. The more vigorous the hygiene becomes, the more it transforms into a lid SCRUB which needs a certain carefulness in order to avoid wounding. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2891f/1487598154283/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie The main pathogenetic factors for obstructive Meibomian Gland Dysfunction are an inspissation of the lipid secretum due to increase melting point and a hyperkeratinization of the ductal system and lid margin. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2892f/1487253605661/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction%2C+MGD+THERAPY_EYE+LID+WARMING.png d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28941/1487535004162/OSCB-Bild_2_Meibomian+Gland_Meibomian+Gland+Dysfunction+%28MGD%29%2C+PHYSICAL+THERAPY+in+MGD+-+Lid+WARMING+from+INSIDE.png d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28938/1487256480326/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie The BLEPHASTEAM Googles for automated application of exactly dosed heat together with moisture is probably the most well known type of MGD Googles Image: Courtesy of THEA Pharma.. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2891c/1487246805184/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28944/1487536529872/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie The most innovative and effective treatment for obstructive Meibomian Gland Dysfunction is presently an automated simultaneous lid warming and gland expression procedure. This is achieved by the LIPIFLOW device that was built according to the ideas of Prof. Donald Korb from Boston, MA, who is a one of the most experienced clinician for Meibomian Gland Dysfunction. (Images: Courtesy of TearScience Inc.) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28922/1487596692326/OSCB-Bild_6.0_Dry+Eye+Disease_MGD_MGD-PATHOPHYSIOLOGY+Main+CONSEQUENCES%2C+LIDRAND-Schema+-+GETEILT+2%2C+Ophthhalmologe+2009.png d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2892c/1487517901251/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2893e/1487276923906/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28925/1487516561616/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie Increased pressure inside the Meibomian glands leads to a PRESSURE ATROPHY with (1) Dilatation of the ductal system, (2) Destruction and Rarefication of the secretory Meibocytes in the Acini and (3) Destruction of the Acini and integration or acinar remnants into the ductal wall. (An overview of a gland in the left top corner shows the area where the higher magnifications of the main image comes from - histological photomicrographs in H&E stain) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd28932/1487255688388/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a35460f77349dd2893b/1487606669409/ d-THERAPIE 4 - MEIBOMDRÜSEN Therapie Manual Meibomian Gland EXPRESSION with the own fingers is possible only to a limited extent and mainly for the lower eye lids as shown here. Expression between thumb and index finger is most effective in the middle of the lid, whereas the nasal and temporal regions are less accessible. Only small amounts of inspissated secretum are expressed here from two orifices in about the middle along the lid. https://oscb-berlin.org/d-overview-therapy-4-antiinflammatory-therapy daily 0.75 2020-11-05 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e10f38ca2cf815a655e2916/1578169238716/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_Rekrutierung+von+Lymphozyten+aus+Gef%C3%A4ssen_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Ein Schlüsselereignis bei der chronischen Entzündung ist die Rekrutierung von Lymphozyten durch Zelladhäsionsmoleküle (CAMs). Lymphozyten mit dem Lymphozyten-Funktions-Assoziierten Antigen 1 (LFA-1), binden an Gefäss-Endothelzellen und auch an Zellen im Gewebe (z.B. Epithelzellen), die das Interzelluläre Adhäsionsmolekül 1 (ICAM-1) tragen. ICAM-1 wird bei einer Entzündung auf Gewebezellen hochreguliert und macht sie anfällig für eine Schädigung durch Lymphozyten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1327a510a69061a71ec11d/1578313648597/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG+-+GEWEBEHORMONE+modulieren+Entz%C3%BCndung_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1308b110a69061a71c2ff9/1597393579179/OSCB-Berlin.org+-+%28c%29+ENK_ANTI-ENTZ%C3%9CNDUNGLICHE+MEDIKAMENTE%2C+gegen+LIPIDMEDIATOREN%2C+Arachidons%C3%A4ure%2C+Eicosanoide_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie NSAID (links in der Mitte der Abbildung) hemmen spezifisch die Enzyme (Cyclooxygenasen, COX), die den Abbau des entzündlichen Grundstoffes Arachidonsäure durchführen. Dabei entstehen Eicosanoide (Prostaglandine und Leukotriene), die hauptsächlich, aber nicht ausschließlich, entzündlich wirken. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e10f3e462ad5d43f3a2b06f/1578169330170/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_Anti-Entz%C3%BCndliche+Medikamente%2C+gegen+Lipidmediatoren%2C+Arachidons%C3%A4ure%2C+Eicosanoide_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e12ffe7c3a000112184c583/1578303475771/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNGS+MEDIATOREN+beim+Trockenen+Auge_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Regulation der Entzündung: Viele verschiedene Signalmoleküle mit einer pro-inflammatorischen Wirkung sind an Entzündungsprozessen beteiligt und regulieren sie. Die Signalmoleküle wirken über die Bindung an einen entsprechenden Rezeptor auf einer Zielzelle. Inflammatorische Zytokine (rot im Diagramm) werden von vielen Zelltypen produziert und können sich im Blut und im Gewebe befinden. Gewebshormone werden lokal im Gewebe gebildet und wirken auch dort. Dies sind z.B. Lipidmediatoren (Eicosanoide) - sie induzieren unter anderem Schmerzen. Vasoaktive Amine wie Histamin und Serotonin werden produziert von Mastzellen (mc im Diagramm) und Phagozyten (Granuklozyten und Makrophagen - im Diagramm 'gr' und 'mo') erhöhen die Durchlässigkeit der Gefässwände. Ein instabiler und daher kurzzeitig und über kurze Distanzen wirkender Mediator ist das Gas Stickstoffmonoxid (Nitric Oxide NO, im Diagramm blau-grün), das hauptsächlich von Makrophagen und von Endothelzellen der Blutgefäße produziert wird. NO bewirkt eine Entspannung der peri-vaskulären glatten Muskelzellen und damit eine Erweiterung des Gefäßes mit anschließendem langsamen Blutfluss. Zusammen mit Histamin fördert dies die entzündliche Extravasation von Plasma und Zellen in das Gewebe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e10f7eedbd43712f4fa01e2/1578170361559/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_Blockierung+des+Zell+Adh%C3%A4sions+Molek%C3%BCls+ICAM-1+mit+dem+Anti-Integrin+Lifitegrast__.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie The interaction of the Cell Adhesion Molecules ICAM-1 on tissue cells and its partner LFA-1 on leukocytic immune cells is a central regulatory and promoting mechanism in the inflammatory pathways in moderated to severe Dry Eye Disease. The blocking of this interaction by a small blocking molecule (Lifitegrast), that is small enough to be applied topically, thus appears as a promising new therapeutic route to treat ocular surface disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1307a51683ea216ca200c2/1578305457702/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNGS+MEDIATOREN%2C+LIPIDMEDIATOREN%2C+Arachidons%C3%A4ure%2C+Eicosanoide_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e05/1578169343883/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Die Quelle der Kortikosteroide und ihrer Vorläufer ist die Nebenniere (Adrenal Gland), von wo aus sie über den Blutstrom im ganzen Körper verteilt werden. Die Nebenniere ist hier in der Abbildung unten in der Mitte über dem "Ovar" zu sehen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e10a21008c15a57c82539a1/1578148380397/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNGS+MECHANISMEN%2C+Kaskade+an+der+Augenoberfl%C3%A4che%2C+aus+The+Ocular+Surface_30_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Phasen einer Entzündung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e11/1488728643555/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9de7/1487156331860/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Das chronische Trockene Auge neigt zur progressiven Verschlimmerung durch selbst-verstärkende Regelkreise der Erkrankung. Der zentrale Faktor bei vielen selbst-verstärkenden Regelkreisen ist eine chronische Entzündung. Dabei werden die normalen Funktions Komplexe zunehmend gestört und das Gewebe der Oberfläche und der Drüsen wird zunehmend beschädigt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e02/1488736567786/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e10f5031683ea216c679287/1578169615438/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_Blockierung+der+T-Zell+Aktivierung+durch+verschiedene+Immunsuppressiva_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Die Abbildung zeigt Moleküle, die für die Antigenpräsentation und die Lymphozyten Aktivierung wichtig sind und somit vielversprechende Ziele für entzündungshemmende Medikamente darstellen. Die derzeit verwendeten und hochwirksamen Medikamente an der Augenoberfläche blockieren die Synthese von zwei wichtigen Signalmolekülen (IL-1 und IL-2). Lifitegrast hat ein anderes Ziel durch Blockierung der Interaktion von Adhäsionsmolekülen (ICAM-1 und LFA-1). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1225ed10a69061a7ff7be8/1578247676921/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_KORTIKOSTEROIDE+-+Angriffspunkte+beim+Entz%C3%BCndlichen+Trockenen+Auge_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Kortikosteroide hemmen alle Phasen einer Entzündung, wie hier dargestellt in einer Abbildung der Entzündungsvorgänge im Gewebe der Augenoberfläche beim chronischen Trockenen Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e1f/1585761341375/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e1302b610a69061a71bb5b3/1578304193754/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG+-+Antigen+Pr%C3%A4sentation+%28durch+MHC+II%29_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e124e9d10a69061a705b1ea/1578258099884/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG_Austritt+von+Blutbestandteilen+aus+Gef%C3%A4ssen+0+Akut_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Als frühes Schlüsselereignis bei Entzündungen werden Blutkomponenten aus den Gefässen rekrutiert, um das Gewebe von Schadstoffen zu befreien. Dies führt zur Ödembildung. Mit Hilfe von Adhäsionsmolekülen auf den Gefäss-Endothelzellen werden Abwehrzellen (Leukozyten) rekrutiert. Bei der akuten Entzündung sind dies vor allem phagozytäre Zellen - bei der chronischen Entzündung sind es vor allem lymphatische Zellen, die das Fortschreiten zur immun-modulierten Entzündung fördern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e19/1487437722757/ d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Topical AZITHROMYCIN, a macrolide antibiotic that was originally developed for infectious ocular surface disease, appears to have if fact multiple favorable effects in Meibomian Gland Dysfunction (MGD). According to literature reports, has: (1) an antibiotic effect against the overgrowth of the commensal lid bacteria, (2) it blocks the breakdown of irritant lipids into potent inflammatory free fatty acids, and (3) it has a stimulating effect on the secretory cells (Meibocytes) of the Meibomian Gland. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e132c9adbd43712f43707f3/1578314917758/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNG+-+PROINFLAMMATORISCHE+ZYTOKINE_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e109f4708c15a57c824fe42/1578147672365/OSCB-Berlin.org+-+%28c%29+ENK_ENTZ%C3%9CNDUNGS+MECHANISMEN%2C+Kaskade+an+der+Augenoberfl%C3%A4che%2C+aus+The+Ocular+Surface_20_.jpg d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5df73a619eff7e06e64b9e1c/1488832684011/OSCB-Bild_6_Dry+Eye+Disease_REGULATORS+of+INFLAMMATION+-Free+Fatty+Acids+-Arachidonic+Acid+%2BEicosanoids++%2B+AZITHROMYCIN.png d-THERAPIE 5 - ANTI-INFLAMMATORISCHE Therapie Azithromycin has an anti-inflammatory effect via several pathways. It limits the metabolism of inflammatory lipid species upstream of the crucial molecule Arachidonic Acid, which leads to its decreased production, and it also inhibits its downstream metabolisation into all the inflammatory Eicosanoids. Further effects concern e.g. an inhibition of inflammatory cytokine and chemokine production by phagocytes. https://oscb-berlin.org/e-facts-1 daily 0.75 2020-11-19 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acc0/1605622843514/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg Short FACTS about Dry Eyes The tear film on the ocular surface needs an oil layer (yellow, left side of the image) on top of the aqueous tears (light blue, in the middle). The oil retards rapid evaporation of the water. A lack of oil increases evaporation (light blue undulated arrows, right side) with subsequent irritation and damage of the delicate tissue (pink stain on the tissue, right side) that cause annoying irritant symptoms. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acc6/1605608600339/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif Short FACTS about Dry Eyes Many desiccating environmental factors come together in office work and may cause "office eye“. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2acd5/1605256829154/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease___Augenoberfl%C3%A4che+und+Dr%C3%BCsen_Ocular+Surface+and+Glands_%2B+MGD+%2B+W%C3%BCste+%2B+Kamele+50%25_10+LINK+BILDCHEN_.jpg Short FACTS about Dry Eyes - ESSENTIALS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2acd3/1605612532825/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg Short FACTS about Dry Eyes - Short FACTS about Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2acd1/1580908241559/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg Short FACTS about Dry Eyes - Deeper INSIGHT for ALL with deeper interest https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2accf/1580908209280/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg Short FACTS about Dry Eyes - OVERVIEW - DOCTOR´s Page https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2accc/1580908189332/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg Short FACTS about Dry Eyes - Quick GLIMPSE - Patient´s Page https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e25d4185dfafe47d3a2acc8/5e25d4185dfafe47d3a2acc9/1580324469528/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg Short FACTS about Dry Eyes - DRY &amp; WET Eye &amp; EYELIDS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acc3/1605559949476/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif Short FACTS about Dry Eyes The eyelids and the eyelid blink are as important for the health of the eye as the tears. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acba/1605554515998/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif Short FACTS about Dry Eyes The surface of the eye (ocular surface) including the eyelids. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acbd/1605683857909/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_400-6-0%2C8_.gif Short FACTS about Dry Eyes Some annoying symptoms of dry eyes are schematically shown here, such as blurred vision, dryness, redness, stinging sensation, burning eyes - here is more information on typical symptoms. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e25d4185dfafe47d3a2acb7/1567154445287/OSCB-Berlin.org_%2528c%2529ENK_Trockenes-Auge%252C-Dry-Eye-Disease_NORMALES%2BAUGE_Beispiel%2BFoto%2B%252B%2BW%25C3%25BCste%252BKamele%2B%252B%2BRand%2B-%2BHELLER_20_.jpg Short FACTS about Dry Eyes https://oscb-berlin.org/e-dry-eye-management daily 0.75 2020-11-20 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4086d500a55c0321113a/1565960391373/OSCB-Berlin.org_THERAPIE%2C+Tr%C3%A4nenersatzittel+Tropfen+auf+Trockenes+Auge_20cm_.jpg MANAGEMENT of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4086d500a55c03211134/1550180314370/LINK-BILDCHEN_QUESTIONNAIRE+Neu.jpg MANAGEMENT of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4086d500a55c03211131/1605805216337/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg MANAGEMENT of Dry Eye Disease => for Questions & Answers to to the “ESSENTIALS” Page https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b2974bc2b3858c2efa533/1580935548705/OSCB-Berlin.org%2C+%28c%29+ENK_OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE%2C+DIAGNOSTICS+ENGLISCH+Overview_14_.jpg MANAGEMENT of Dry Eye Disease https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4086d500a55c0321112e/1568958870888/Diagnostik+und+Therapie%2C+Abbildung+f%C3%BCr+LINK+BANNER_3+f%C3%BCr+Erkennen+%26+Behandeln%2C+Patient%2C+Arzt%2C+Fragezeichen%2C+Schlange_.jpg MANAGEMENT of Dry Eye Disease https://oscb-berlin.org/e-diagnosis-overview daily 0.75 2021-03-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cee/1568371842313/Diagnostik+MEIBOGRAPHIE+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b20f68a35a3376ead301c/1580933391628/OSCB-Berlin.org%2C+%28c%29+ENK_OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE%2C+DIAGNOSTICS+ENGLISCH+Overview____.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d0e/1605535098073/OSCB-Berlin.org_Lidrand-Parallele-Conjunctivale-FALTEN-%28LIPCOF%29-der-Bindehaut-treten-auf-durch-Besch%C3%A4digung-des-Bindegewebes-bei-Chronischem-Trockenen-Auge_3+9-19_20_.jpg DIAGNOSIS - Clinical TESTS Lid Parallel Conjunctival Folds (LIPCOF) are a clinical sign of tissue damage in chronic dry eye disease. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d1a/1614859061803/SCHIRMER-Test%2C+Tr%C3%A4nen%2C+Trockenes+Auge%2C+Sicca%2C+Tears%2C+Tear+Film+Dry+Eye+Disease_Ohne+Text+mit+STREIFEN_20_%28c%29+ENK%2C+www.OSCB-Berlin.org__.jpg DIAGNOSIS - Clinical TESTS The bent edge of the test strip is inserted into the lower fornix over the lateral third of the lid margin. Then the eyes are largely closed during the 5 minutes of the test. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89ce2/1568371510153/Diagnostik+R%C3%96TUNG+der+Bindhaut+Test+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cd0/1568370162817/Diagnostik+NI-BUT+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89ce5/1568371598218/Diagnostik+ENTZ%C3%9CNDUNGS+MARKER%2C+MMP9+Test+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d1d/1545026618474/OSCB-Berlin.org_DIAGNOSTISCHE-Expression-der-Meibomdr%C3%BCsen-mit-einem-standardisierten-Druckapplikator--%28Meibomian-Gland-Evaluator%2C-MGE%29.gif DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89ccd/1568369665695/Diagnostik+LIPIDSCHICHT+DICKE+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cd9/1568371303168/Diagnostik+F-BUT+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89ce8/1546781461907/Diagnose-Symbolbild_TR%C3%84NEN+-+PRODUKTION.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb29ebea840865ca1b6b0b6/1605541580806/Spezialisierte%2BGer%25C3%25A4te%2Bf%25C3%25BCr%2Bdie%2BMeibographie_%2528c%2529ENK%252C%2Bwww.OSCB-Berlin.org_.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cf6/1544791444710/Inkompletter+Lidschlag%2C+Lidschlag+FREQUENZ%2C+LIPIVIEW_LINK-BILDCHEN_.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/604fad9cfbbf552b49e90235/1615834543186/OSCB-Berlin.org%252C%2B%2528c%2529%2BENK_Dry%2BEye%2BDisease%252C%2BContact%2BLenses_Trockenes%2BAuge_NICHT-Invasive%2BBUT%2B%2528NIBUT%2529_20__.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d0b/1568225246067/OSCB-Berlin.org_%28c%29-by-ENK-Erich-u-Nadja-Knop_Dry+Eye%2C+Trockenes+Auge_OXFORD+Scheme+for+Vital+Staining%2C+Vitalf%C3%A4rbung%2C+Cornea+Epithelium+Kornea%2C+Hornhautepithel_20_.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d14/1544819517595/Animation_Trocknes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d20/1544992208083/Dual+Mode+DMI+Meibography_LipiVIEW+und+LipiSCAN%2C+TearScience_.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cff/1568135652221/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_Der+TR%C3%84NEN+MENISKUS+ist+ein+Indikator+f%C3%BCr+die+Tr%C3%A4nen-MENGE+auf+dem+Auge_20_.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cdc/1568371403549/Diagnostik+VITAL+F%C3%84RBUNG+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cca/1568372748064/Diagnostik+LIPIDSCHLAG+ANALYSE+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cd6/1568370684701/Diagnostik+OSMOLARIT%C3%84T+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d08/1544811421056/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__VITALF%C3%84RBUNG+macht+Zellsch%C3%A4den+sichtbar+an+der+Spaltlampe.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e3b20b1b79ef1475c4b6dcd/1605449605579/OSCB-Berlin.org%2C+%28c%29+ENK_OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_DIAGNOSE%2C+DIAGNOSTICS+ENGLISCH+Overview_14_.jpg DIAGNOSIS - Clinical TESTS => go directly to the overview according to CLINICAL ORDER https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89ceb/1568371820992/Diagnostik+DIAGNOSTISCHE+EXPRESSION+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/604fadf106c7a77c0ebe3fb7/1615834649491/OSCB-Bild_6.0_Dry+Eye+Disease_DIAGNOSIS_FULLY+AUTOMATED+-+INTERFEROMETRY+%26+ANALYSIS+of+the+Tear+Film+LIPID+LAYER+%28TFLL%29_HOCHKANT.png DIAGNOSIS - Clinical TESTS In the upper image, the lipid layer is sufficiently thick (Avg.ICU 90) recognizable by the rich blue and gold tones of the interference colors that indicate the thickness. In the lower image, the lipid layer is much too thin (Avg. ICU 35) recognizable by the very pale, almost absent coloration. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d17/1558377639104/BonOptic_ABNAHME+an+AUGE_Inflamma_dry_taking_sample.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cdf/1568277396092/Diagnostik+LIPCOF+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fcce24dfe657040d591505d/1607262834373/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_20-18-0%2C2_.gif DIAGNOSIS - Clinical TESTS The break-up of the thin tear film becomes visible when the tears are stained with the fluorescein dye that is observed in blue light. A break-up occurs as a dark area (seen here in the middle of the faint “C” of the OSCB overlay). The break-up of the tear film is the stimulus that triggers an eyelid blink in order to distribute a new tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cd3/1568370154896/Diagnostik+TR%C3%84NEN+MENGE+%2B+Text.jpg DIAGNOSIS - Clinical TESTS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89d02/1544876161777/Die+Wasser-Verdunstung+beim+EVAPORATIVEN+Trockenen+Auge+f%C3%BChrt+zu+Tr%C3%A4nen-Film+HYPEROSMOLARIT%C3%84T_www.OSCB-Berlin.org_20_.jpg DIAGNOSIS - Clinical TESTS With increased evaporation (blue arrows) of the tear water, the dissolved substances (salts and proteins - in the figure as white balls) are more concentrated. This leads to locally thin with increased salt concentration (hyperosmolarity), and thus to burning eyes and cell damage . https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f4116b1101d2968b89cc4/1561657013748/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg DIAGNOSIS - Clinical TESTS https://oscb-berlin.org/e-external-risk-factors daily 0.75 2020-11-25 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b21c/1547400547266/OSCB-Berlin.org_Ocular+Fitness+to+fight+Dry+Eye+Disease_Augen+Fitness+gegen+das+Trockenen+Auge_%28c%29ENK_20_.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b219/1546199766947/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_30_%2Cjpg.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e316075dd743e65e652cddf/1580294277877/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29+%281%29.gif HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b222/1567410087727/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b21f/1547394276842/OSCB-Berlin.org_Dietary+Improvement+against+Dry+Eye+Disease_Ausreichende+Di%C3%A4t%2C+Trinkmenge+gegen+das+Trockene+Auge_%28c%29ENK_20_.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b228/1547385983226/PLANTS+against+Dry+and+Polluted+Air+in+Dry+Eye+Disease_PFLANZEN+geben+Trockene+und+Staubige+Luft+beim+Trockenen+Auge_20__.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b225/1561646256142/OSCB-Berlin.org_BRILLE+mit+VERDUNSTUNGSSCHUTZ+gegen+das+Trockene+Auge%2C+Spectacles+with+EVAPORATION+PROTECTION+for+Dry+Eye+Disease_%28c%29+ENK_2_20_.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b22b/1547395795933/OSCB-Berlin.org_No+Contact+Lens+Wear+in+Dry+Eye+Disease_Kein+Kontaktlinsentragen+beim+Trockenen+Auge_%28c%29ENK_20_.jpg HOME REMEDIES for Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f41f8367de60ba6d4b216/1561654268908/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE_LINKBILDCHEN_Austrocknender+Risikofaktoren_3_.jpg HOME REMEDIES for Risk Factors https://oscb-berlin.org/e-tear-subst-overview daily 0.75 2021-06-04 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31786c9258077073316d41/1580300408029/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_+%281%29.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb7debfda1109239aa8a410/1605885648015/OSCB-Berlin.org+%28ENK%29+TEAR+SUPPLEMENTS%2C+Overview_.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f422386b0645647ea5731/1578771382599/%C3%9Cbersicht+TR%C3%84NENERSATZ+LINK-Bildchen_Neu+2_.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb77504b259c607b5778fb1/1605895256059/%C3%9Cbersicht+TR%C3%84NENERSATZ+LINK-Bildchen_Neu+2_.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? => directly for the SELECTION of different Tear Supplements (´Artificial Tears´) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb79a87d5e88918f433b7c9/1605868209585/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye%2C+Aqueous+Tear+Supplement%2C+HYALURONIC+ACID+BINDS+WATER_Trockenes+Auge%2C+Sicca%2C+W%C3%84SSRIGES+TR%C3%84NENERSATZMITTEL%2C+HYALURONS%C3%84URE+bindet+Wasser+2_20_.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? In aqueous tear substitutes , water ( H2O ) is bound to large water-binding molecules - often hyaluronic acid ( HA ) - so that it stays on the surface of the eye for longer time and protects it. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdc84081d1e474906722a40/1608287251094/OSCB-Berlin.org-%28c%29-ENK_Animation_Tr%C3%A4nenfilm-Hyperosmolarit%C3%A4t-%2B-Hypotone-Tr%C3%A4nenersatzmittel_2_20-22-0%2C8_.gif Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e5aae53e6c06e061f89ccf9/1583001181803/OSCB-Berlin.org%2C+%28c%29+ENK_STERILE+DISPENSER+BOTTLE+%26+Single+Units%2C+EDO+for+Tear+Supplements+for+Dry+Eye_ENGLISH+20_.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f422386b0645647ea5725/1578770962147/6_OSCB-Berlin.org_%28c%29ENK_DRY+EYE+BANNER%2C_Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE_LINKBILDCHEN_Therapie_%2B+WASSERTROPFEN_2.jpg Tear SUPPLEMENTS - Overview - If? - When? - Why? - What? https://oscb-berlin.org/e-mdd-blepharitis-overview daily 0.75 2020-12-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42c1cd500e3b8b0875ea/1554661894816/www.OSCB-Berlin.org_DEMODEX+Milben+und+BAKTERIEN+Normale+Flora+auf+dem+Lidrand+bei+Meibomdr%C3%BCsen+St%C3%B6rung%2C+MDD%2C+MGD+und+BLEPHARITIS+2_20_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31aae92478111b6835639e/1606841319558/GIF-Animation_Some-Clinical-SIGNS-in-Meibomian-Gland-Dysfunction-%28MGD%29_Einzel-BILDER_600pix-21-4_%2BOSCB.gif MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye Schematic animated illustration of the development of some important pathological changes on the edge of the eyelid. These occur in various chronic diseases of the eye, including chronic Meibomian gland dysfunction (MGD). => please see here for a photo of incrustations on the eyelid margin and eyelashes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc22475fa04221c71680226/1606558878302/OSCB-Berlin.org_%28c%29%2BENK_Dry%2BEye%2BDisease%2C%2BTrockenes%2BAuge_Meibomdr%C3%BCsen%2BDysfunktion%2B%28MDD%2C%2BMGD%29%2Bmit%2Bverstopften%2Bund%2Birregul%C3%A4ren%2B%C3%96ffnungen%2Beingedicktes%2BSekret%2Bwird%2Bausgepresst_20_OT_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31b11c6f5f28494270d6af/1581795504113/Meibomdr%C3%BCsen+BASIS+Therapie_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42c1cd500e3b8b0875e7/1605780366899/Meibomddr%C3%BCsen+SPEZIALISIERTE+Therapie_10+LINK+BILDCHEN.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye => Meibomian gland APPARATIVE Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2ad5e593b9eb78b41f76af/1596642842805/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____OIL+DEFICIENCY+%2B+EVAPORATION%2C+%C3%96l-Mangel+f%C3%BChrt+zu+erh%C3%B6hter+Verdunstung+mit+Trockenem+Auge_20_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye Oil deficiency on the tear film results in evaporation of the tear water with subsequent dry eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42c1cd500e3b8b0875e4/1581795423195/Meibomdr%C3%BCsen+BASIS+Therapie_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye => Meibomian Gland BASIC Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31b145e00e956306eed5fb/1581795487308/Meibomdr%C3%BCsen+APPARATIVE+Therapie+2_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42c1cd500e3b8b0875e1/1554661894803/Konjunktivaler+R%C3%96TUNGSGRAD+auf+MGD%2C+MDD%2C+Blepharitis%2C+Trockenes+Auge%2C+Sicca+Montage_BANNER_.jpg MEIBOMIAN GLAND Dysfunction - Oil Deficiency - Dry Eye https://oscb-berlin.org/e-lidentzundung-blepharitis-demodex-milben daily 0.75 2021-04-12 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb6453eaab47d5610fad958/1606667324854/DEMODEX-Therapie_30%2BLink%2BBildchen_2_.jpg LID INFLAMMATION/Blepharitis - DEMODEX => directly to therapy options exclusively for DEMODEX mites https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42efd500a55c0321bd35/1579697455843/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+REINIGUNGSMITTEL%2C+Teebaum-Schaum+%2B+T%C3%BCcher_20_.jpg LID INFLAMMATION/Blepharitis - DEMODEX https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42efd500a55c0321bd38/1606667880400/DEMODEX-Therapie_10+Link+Bildchen__.jpg LID INFLAMMATION/Blepharitis - DEMODEX => Some therapy options for DEMODEX mites in chronic bleparitis https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb94d27158b28734bb06853/1606752404337/Thea_DEMODEX_FOTOS+Demodex+im+Mikroskop+%2B+Wimpern+in+Spaltlampe_hoch+%2B+Text_ENGLISCH_.jpg LID INFLAMMATION/Blepharitis - DEMODEX Demodex Mites on a glass object tray as seen in a light microscope (upper image) - they live in the hair follicles of the eyelashes. Their remains often form typical cylindric deposits at the base of the eyelashes (lower image). Images courtesy of Laboratoires Théa. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42efd500a55c0321bd2f/1606729104078/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+mit+Pinzette%2BDrehen_20_.jpg LID INFLAMMATION/Blepharitis - DEMODEX Demodex hair mites can often be seen better in the slit lamp if the eyelashes are twisted against the direction of growth using tweezers https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc220453485235c860f1c90/1606667315104/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Lid-Hygiene%2B%26%2BLid-Care%2BProducts_BANNER_.jpg LID INFLAMMATION/Blepharitis - DEMODEX => directly to Eyelid Hygiene & Lidcare https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb932eacaf0401020cea38c/1606815104633/oscb-EYECARE_Lid+Inflammation+BLEPHARITIS+LINK+Bildchen+10__.jpg LID INFLAMMATION/Blepharitis - DEMODEX Chronic blepharitis is typically a long standing condition with red and slightly swollen eyelid margins which often cause few complaints. - It is important to exclude other more acute and more severe conditions - therefore an eye doctor should always be consulted ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4146a7bab6ba3cfa70d378/1606746315084/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5_.gif LID INFLAMMATION/Blepharitis - DEMODEX The harmless normal Demodex Hair Miltes reside in the hair follicles of the eyelashes, where they also multiply. They are mobile and can glide along the lashes. Their remains form typical cylindrical scales at the base of the eyelashes. In case of chronic eyelid inflammation (chronic blepharitis) the number of demodex is increased.=> here is a microscope image of Demodex mites https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e2f42efd500a55c0321bd32/1579692793117/OSCB-Berlin.org+-+%28c%29+ENK_DEMODEX+Haarmilben+mit+Pinzette%2BRausziehen_20_.jpg LID INFLAMMATION/Blepharitis - DEMODEX After removing an eyelash, Demodex mites typically hang from the hair follicle and can be diagnosed on the slit lamp. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e4145e14b6b8940eeda9bb0/1581336035439/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5_HALB-BANNER_.gif LID INFLAMMATION/Blepharitis - DEMODEX https://oscb-berlin.org/d-1-start4-tieferer-einblick-in-das-trockene-auge-1 daily 0.75 2020-01-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3258899b02893ab661f/1567176570800/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BSCIENTIST%2Bmit%2BAuge.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a25/1580331818950/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Die-Augen-Bindehaut-Konjunktiva-hat-eine-empfindliche-Oberfl%C3%A4chenstruktur%2C-Epithel-mit-Becherzellen%2C-Mikrovilli-und-Glykokalyx-%28Koloriertes-LM-%2B-TEM_ALS+JPG_20_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a74/1509125946519/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab69fb/1509125946492/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a4f/1580331818957/SCHIRMER-Test%2C+Tr%C3%A4nen%2C+Trockenes+Auge%2C+Sicca%2C+Tears%2C+Tear+Film+Dry+Eye+Disease_Ohne+Text+mit+STREIFEN_20_%28c%29+ENK%2C+www.OSCB-Berlin.org__.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a29/1509125946502/OSCB-GIF_BLINZELN%2C+BLINK+Animation+%28QUER+%2B+FRONTAL%29_1-7_PSD-JPGs+%2B+PPT-Folien+%2B+TEXT+%2B+TR%C3%84NENFLUSS+%2820cm-72dpi%29_33-10fps+GIF.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Diese schematische Animation des LIDSCHLAGES illustriert die prinzipielle Funktion der Augenlider zur Verteilung der Tränen in einen dünnen Film im Bereich der Lidspalte um das Gewebe der Augenoberfläche dort auch bei geöffnetem Auge feucht zu halten. Eigentliche Tränentropfen treten im Bereich der Lidspalte allerdings nur bei verstärktem Tränenfluss auf. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a00/1580331818943/OSCB-Berlin.org_%28c%29-ENK--Erich-and-Nadja-Knop_AUGENOBERFL%C3%84CHE-%26-TR%C3%84NEN%2C-ANIMATION-NEU_20-8-2_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) In der Zeichnung ist die Tiefe des Konjunktivalsackes und die Dicke des Tränenfilms übertrieben gross dargestellt, damit man sie sehen kann - tatsächlich liegen die Lider praktisch direkt auf dem Augapfel, der Bindehaut-Sack bildet nur einen feuchten Spaltraum, und der Tränenfilm ist äusserst dünn. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a71/1509125946517/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a22/1580331818946/OSCB-Berlin.org_FEINSTRUKTUR-der-AUGENOBERFL%C3%84CHE-und-TR%C3%84NENFILM+%2B++PSE+AUSSCHNITT+Mikrovilli+u.+Muzin.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a79/1509125946521/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a59/1580331818961/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a3c/1509125946507/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Die beiden grundlegenden Voraussetzungen für die Gesundheit der Augenoberfläche und für das intakte Sehen sind die Bildung von Tränenflüssigkeit und die Herstellung eines stabilen Tränenfilms daraus. Entsprechend sind die beiden wichtigsten Faktoren für die Entstehung eines Trockenen Auges ein Mangel an Tränenflüssigkeit und/ oder ein Problem bei der Herstellung eines ausreichend stabilen Films daraus. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a33/1509125946509/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Interessanterweise ist die Bildung der Ölschicht des Tränenfilms von grösserer Bedeutung als die Bildung von Tränenwasser, da bei Öl-Mangel auch reichliches Tränenwasser schnell verdunstet. Es entstehen dann Lücken im Tränenfilm und die empfindlichen Zellen der Augenoberfläche werden geschädigt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a1e/1555257764514/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Ein BLICK IN DEN TRÄNENFILM. Der mittlere Hauptteil des Tränenfilms vor der transparenten Hornhaut/ Kornea besteht aus wässriger Flüssigkeit. Unten sind die zahlreichen fingerartigen Fortsätze der oberflächlichen Epithelzellen sichtbar - sie binden das Wasser an die Zell-Oberfläche. Im Tränenfilm wird das Wasser durch die langen Zuckerketten (hier rötlich) löslicher Schleimstoffe (Muzine) gebunden, die im Tränenfilm treiben und das Wasser in ein dünnflüssiges Wasser-Muzin-Gel verwandeln. Oben wird der Tränenfilm von der sehr dünnen Öl-Schicht aus den Fetten der Meibomdrüsen abgedeckt, die eine zu schnelle Verdunstung des Tränenwassers verhindert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a19/1567176570839/TR%C3%84NENFILM-%28-und-Augenoberfl%C3%A4che%29__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Der TRÄNENFILM (links) besteht aus 3 Schichten, deren Bestandteile von 3 verschiedenen Arten von Augen-DRÜSEN (rechts) produziert werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a42/1509125946511/OSCB-Berlin.org_GIF-Animation_Typische-SYMTOME-beim-Trockenen-Auge_Bild-1-4v4_10-72_6-x2sec-PSE__.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a6e/1509125946516/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Die Neuronale Regulation der Augenoberfläche, über die Hirnnerven V (Trigeminus) und VII (Facialis) im Hirnstamm, und auch ihre Emotionale Wahrnehmung im Gehirn ist komplex. Damit ist sie anfällig für Störungen, kann aber auch gewisse individuelle Unterschiede zwischen verschiedenen Menschen zeigen. Hier gehen auch Erfahrungen, Bewertungen und verschiedene Arten der Bahnung und Verarbeitung von Ereignissen an der Augenoberfläche ein. Es ist ja auch eine Erfahrung des täglichen Lebens, dass das´Nervenkostüm´ bei jedem Menschen durchaus etwas unterschiedlich sein kann. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a7c/1567176570854/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a65/1580331818976/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a07/1509125946495/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Die FEUCHTIGKEIT der Augenoberfläche ist nötig, um die Hornhaut/ Kornea TRANSPARENT zu halten https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a11/1509125946497/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Der kontinuierliche Verlauf der Tränen über die Augenoberfläche, der für ihre Gesundheit von grösster Wichtigkeit ist, geht (in der Abbildung von links nach rechts): (1) vom Hauptproduktionsort in der Tränendrüse über (2) die sichtbare Hornhaut/ Kornea und Bindehaut/ Konjunktiva, die ständig gebadet werden müssen, in (3) die Ableitenden Tränenwege, die die ´gebrauchten´ Tränen in die Nase ableiten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a39/1580331818953/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+SQUAMOUS+METAPLASIA_Trockenes+Auge%2C+PLATTENEPITHEL+METAPLASIE+%28LM%2BSEM%29_20_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a49/1533151076135/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Die animierte schematische Zeichnung, zeigt einen sehr instabilem Tränenfilm. Hier bleibt er nach einem Lidschlag nur für etwa eine einzige Sekunde stabil ehe er aufbricht. Dies weist auf eine starke Störung des Systems hin und lässt nachfolgende Gewebeschädigung vermuten. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a55/1569330809562/OSCB-Berlin.org_Klinische+BEFUNDE+beim+Trockenen+Auge.png d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3258899b02893ab661c/1567176570797/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a45/1567176570847/GIF-Animation-TROCKENES-AUGE%2C-DRY-EYE-SYMPTOME_Kennen-Sie-das-auch_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a14/1567176570842/OSCB-Berlin.org_Dry-Eye-Disease%2C-Trockenes-Auge%2C-%28c%29ENK_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-2x-3D-%C3%96L_NEU-HH%2BIRIS-3D-%2BHH-WEISS-WEB_2_20_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a62/1580331818969/TEXT%2BKOMM_OSCB%2C+ENK_LIDER+%28FRONTAL%29+Animation+BLINZELN_%28aus+KL+Weich%29_Folie+VERKL.25b+x+25cm+h+ALS+Gr%C3%B6sse+Opt.%2BNEU+MAN.Verschob_DRY+SPOT+FLUO+%2815cmx72dpi%29+UP-DOPPELT+36-10fps+GIF.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a6b/1580331818979/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a7f/1509125946524/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69f5/1570043429128/OSCB-Berlin.org_c+by+ENK%2C+Erich+%26+Nadja+Knop_Ocular+Surface%2C+Tearfilm%2C+Tr%C3%A4nenfilm+Augenoberfl%C3%A4che_Feinstruktur+von+Augenoberfl%C3%A4che+und+Tr%C3%A4nenfilm%2C+Neuer_10+LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - ZELLEN der Oberfläche (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69ea/1567176570836/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__RISK+FACTORS+for+DRY+EYE+DISEASE%2C+RISIKOFAKTOREN+f%C3%BCr+das+TROCKENE+AUGE+%28Ohne+Text%29_10+LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - RISIKOFAKTOREN für das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69e5/1567176570832/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___SYMPTOMS+in+Dry+Eye+Disease_10+LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - SYMPTOME beim Trockenen Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69e0/1567176570828/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__%C3%96L+MANGEL+im+Tr%C3%A4nenfilm+f%C3%BChrt+zu+Gewebesch%C3%A4den_jpg6_10_LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - PATHOGENESE des Trockenen Auges (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69db/1567176570825/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__CLINICAL+SIGNS+of+Dry+Eye+Disease_jpg6_10_LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - KLINISCHE ZEICHEN des Trockenen Auges (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3308899b02893ab69ca/1567176570821/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__AUGENLIDER_jpg6_10_LINK+BILDCHEN_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - Die Augen-LIDER (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3268899b02893ab6660/1567176570819/TR%C3%84NENFILM-%28-und-Augenoberfl%C3%A4che%29__Augenoberfl%C3%A4che-FOTO-EIGENES-AUGE-%2B-AUGE-QUER-Davos-%2B-%C3%9CBERBLENDET_GANZ-KURZ-%2B-TR%C3%84NENFILM-3D-NEU-2.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - Tränen-FILM auf der Augenoberfläche (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3268899b02893ab665c/1567176570816/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - TRÄNENFLUSS über die Augenoberfläche (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3268899b02893ab6658/1567176570812/OSCB-GIF_DEWS+II._PPT+VORLAGEN_-20%25+KOPIE%2B10hoch_4+Basteln_VICIOUS+CIRCLE+GLAND+DYSFUNCTION_5-2fps_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - CHRONISCHE VERSCHLIMMERUNG des Trockenen Auges (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3258899b02893ab6624/1567176570809/OSCB-Berlin.org_Augenoberfl%C3%A4che-%E2%80%93-Nervensystem-%E2%80%93-Gef%C3%BChl-%E2%80%93-SCHMERZ.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - SCHMERZ-Syndrome (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5e31f3258899b02893ab6621/5e31f3258899b02893ab6622/1567176570804/OSCB-Berlin.org_DIE+AUGENOBERFL%C3%84CHE.png d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) - Die AUGENOBERFLÄCHE (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a5d/1580331818964/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM_NUR-BLINZELN-9-19_500-16-1_.gif d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a2f/1509125946504/ d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e31f3308899b02893ab6a4c/1567176570850/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___TYPISCHE+BEFUNDE+des+TROCKENEN+AUGES_20_.jpg d-1-start4-TIEFERER EINBLICK in das Trockene Auge (Copy) Ein mäßiges Trockenes Auge zeigt typischerweise nur eine leichte Rötung der Bindehaut- und gegebenenfalls der Lidränder. Die Öffnungen der Meibomschen Talgdrüsen werden oft durch sichtbares oder unsichtbares verdicktes Sekret verstopft - dies ist die häufigste Hauptursache des Trockenen Auges. Oberflächendefekte erscheinen in der Vitalfärbung mit Fluoreszein als Keratitis superficialis punctata (KSP). https://oscb-berlin.org/e-ipl-therapy daily 0.75 2021-02-22 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e482b9883fe885c7703e375/1606903611165/OSCB-Berlin.org__Trockenes+Auge%2C+Dry+Eye+Disease%2C+Meibomian+Gland+Dysfunction%2C+MGD%2C+MDD_Intense+Pulsed+Light+%28IPL%29+Schematic+Procedure_20_.jpg ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy Usually about 4-5 flashes of light are applied onto the skin. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e511fed6dd0756fb8c9ff95/1582393420833/IPL+Ger%C3%A4te+%C3%9Cbersicht_10+LINK+BILDCHEN__.jpg ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy => DIRECTLY to IPL device overview https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e516002b9df9733cce54e76/1582393420836/OSCB-Berlin.org---%28c%29-ENK_IPL+Mechanism+of+Action+on+Blood+Vessels_20_.jpg ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e5280cedbfcb2688e24d4d0/1606903816802/IPL-Eyelight_HANDST%C3%9CCK-mit-Licht-APPLIKATOR_ANIMATION_10-2-0%2C5_.gif ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy The light flashes are applied with a handpiece. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e482b9883fe885c7703e372/1606910412995/IPL-Animation_Intense-Pulsed-Light_%28c%29ENK%2C-www.OSCB-Berlin.org_.gif ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy The IPL technique uses very strong white light flashes around the eye. The eye itself must remain covered. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e511f55169a2139bb617144/1582393420839/IPL+Ger%C3%A4te+%C3%9Cbersicht_10+LINK+BILDCHEN__.jpg ENGLISCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy https://oscb-berlin.org/d-ipl-therapy daily 0.75 2021-02-22 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e51684c29ef91017449a4cc/1582375104421/IPL+Ger%C3%A4te+%C3%9Cbersicht_10+LINK+BILDCHEN__.jpg DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy => DIRE KT zur IPL-Geräteübersicht https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e51684c29ef91017449a4cf/1606903632203/IPL-Animation_Intense-Pulsed-Light_%28c%29ENK%2C-www.OSCB-Berlin.org_.gif DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy Die IPL Technik verwendet sehr starkes weisses Blitzlicht um das Auge herum. Das Auge selbst muss abgedeckt bleiben. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e51684c29ef91017449a4d2/1606903585757/OSCB-Berlin.org__Trockenes+Auge%2C+Dry+Eye+Disease%2C+Meibomian+Gland+Dysfunction%2C+MGD%2C+MDD_Intense+Pulsed+Light+%28IPL%29+Schematic+Procedure_20_.jpg DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy Es werden meist 4-5 Lichtblitze auf die Haut gegeben. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e51684c29ef91017449a4d5/1606905109142/OSCB-Berlin.org---%28c%29-ENK_IPL+Mechanism+of+Action+on+Blood+Vessels_20_.jpg DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e5282bd576c4c1eab72f797/1606903728835/IPL-Eyelight_HANDST%C3%9CCK-mit-Licht-APPLIKATOR_Animation_20-2-0%2C5_.gif DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy Die Lichtblitze werden mit einem Handstück appliziert. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5e51684c29ef91017449a4d8/1596557474113/IPL+Ger%C3%A4te+%C3%9Cbersicht_10+LINK+BILDCHEN__.jpg DEUTSCH IPL Meibomian Glands - IPL - Intense Pulsed Light-Therapy https://oscb-berlin.org/literatur daily 0.75 2020-07-27 https://oscb-berlin.org/d-info-1-was daily 0.75 2020-07-19 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eae/1529869348302/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ec6/1580040619967/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg d-Information-1-Facts, simple Die Meibom-Öldrüsen in den Augenlidern bilden normalerweise (links) Öl für den Tränenfilm, das die Verdunstung des Tränenwassers hemmt. Wenn die Öldrüsen verstopft sind (rechts) verdunstet das Tränenwasser schnell und es kommt zum Trockenen Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461edf/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461e97/1567176374003/Animation_Trockenes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fa67d9880deb847707/1594882045378/Information-4-RISIKO-FAKTOREN_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fc4d23d17847269335/1594882046210/Information-8-THERAPIE_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff988f4baae4ad46d4c00/1594882442557/Information-6-SCHADEN_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ffbdbecfc5d24a82d39a9/1595170418619/Information-1-WAS+IST_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fbf40acf6926cef171/1594882045245/Information-3-URSACHE_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fb5db09b3263862f7a/1594882045818/Information-2-BESCHWERDEN_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fafb223d5eaf29d175/1594882044376/Information-7-VERSCHLIMMERUNG_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f0ff7fa9809d922841f3309/5f0ff7fab3ff02189c609d36/1594882044514/Information-5-TROCKENHEIT_Neu2_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ecf/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ed5/1529244871759/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ea7/1580040619955/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C+Gewebe+Reizung_NEU_OHNE%2BText_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ec0/1580040619964/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eb1/1567176374008/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel%2C-%2B-Tr%C3%A4nenfluss%2C-langsam__.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461e9e/1529244871746/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461e94/1581975191064/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg d-Information-1-Facts, simple => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ecc/1567502777033/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ec3/1567176374014/Henrik+SJ%C3%96GREN_Download.jpg d-Information-1-Facts, simple Henrik SJÖGREN, schwedischer Augenarzt, der als erster die nach ihm benannte entzündliche Erkrankung der Tränen- und Speicheldrüsen beschrieben hat, die zum Sicca Syndrom von Auge und Mund führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ed8/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eaa/1580040619958/OSCB-Berlin.org+-+%28c%29+ENK_Bildung+von+ABLAGERUNGEN+auf+dem+Lidrand_ANIMATION+-+EINZELBILD+daraus_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ed2/1580040619972/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ebd/1529869348309/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461e9a/1529244871744/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eb4/1580040619961/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ee2/1532291687008/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eba/1594736018347/GIF_BLINZELN%2C-BLINK-Animation-%28NUR-QUER%29_von+2.2+auf+0%2C14MB_5-25-0%2C2_.gif d-Information-1-Facts, simple Schematische Darstellung der Augenoberfläche im Querschnitt. Der Lidschlag bildet aus der Tränenflüssigkeit den Tränen-Film. Störungen des regelrechten Lidschlages sind also ein typischer Grund für Störungen des Tränen-Film und damit für ein Trockenes Auge ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461edc/1580040619975/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung_Animation--DEUTSCH-600-2-0%2C5_NEU-anderes-Bild_.gif d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461eb7/1594736018342/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che%2C+FOTO%2BSCHEMA_20_.jpg d-Information-1-Facts, simple https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcf74c4fe941124461ec9/1580040619969/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_+%281%29.gif d-Information-1-Facts, simple Inkompletter Lidschlag https://oscb-berlin.org/information2ftak-einfach-copy daily 0.75 2020-07-14 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15caa/1580040619972/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c77/1529244871746/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT+des+Trockenen+Auges%2C+Frequency+of+Dry+Eye+Disease_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15cb6/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c80/1580040619955/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C+Gewebe+Reizung_NEU_OHNE%2BText_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c8c/1580040619961/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c98/1580040619964/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye%2C+_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c83/1580040619958/OSCB-Berlin.org+-+%28c%29+ENK_Bildung+von+ABLAGERUNGEN+auf+dem+Lidrand_ANIMATION+-+EINZELBILD+daraus_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15ca1/1580040619969/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_+%281%29.gif d-Information-2-Complaints Inkompletter Lidschlag https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c74/1529244871744/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c92/1594736018347/GIF_BLINZELN%2C-BLINK-Animation-%28NUR-QUER%29_von+2.2+auf+0%2C14MB_5-25-0%2C2_.gif d-Information-2-Complaints Schematische Darstellung der Augenoberfläche im Querschnitt. Der Lidschlag bildet aus der Tränenflüssigkeit den Tränen-Film. Störungen des regelrechten Lidschlages sind also ein typischer Grund für Störungen des Tränen-Film und damit für ein Trockenes Auge ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c8f/1594736018342/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che%2C+FOTO%2BSCHEMA_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15cb3/1580040619975/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung_Animation--DEUTSCH-600-2-0%2C5_NEU-anderes-Bild_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15ca7/1529244871752/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c86/1529869348302/Animation-UNSCHARF-Sehen-%28aus-Animation-Trockenes-Auge%2C-Dry-Eye%29_NEU-600-6-0%2C5_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15cb0/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15cb9/1532291687008/ZIELGRUPPEN-Symbol-Bilder+VERSCHIEDENE+4+SAMMLUNG+mit+Auge+jpg3-72+2.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c71/1567176374003/Animation_Trockenes-Auge+Gef%C3%A4sse+R%C3%B6tung%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15ca4/1567502777033/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c89/1567176374008/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel%2C-%2B-Tr%C3%A4nenfluss%2C-langsam__.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15cad/1529244871759/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_635-12-1%2C0_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c6e/1581975191064/OSCB+HOME-Page_FAKTEN+%26+INFORMATIONEN%2C+BANNER+als+LINK+%2B+SCHRIFT+20_6__.jpg d-Information-2-Complaints => ZURÜCK zur SEITEN-Auswahl für FAKTEN https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c7a/1529244871748/GIF+Animation_Typische+Symptome+beim+Trockenen+Auge_Bild+4v4_20-72_4-0.5fps_.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c9b/1567176374014/Henrik+SJ%C3%96GREN_Download.jpg d-Information-2-Complaints Henrik SJÖGREN, schwedischer Augenarzt, der als erster die nach ihm benannte entzündliche Erkrankung der Tränen- und Speicheldrüsen beschrieben hat, die zum Sicca Syndrom von Auge und Mund führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c7d/1580040619948/OSCB-GIF_3.7_Augenoberfl%C3%A4che-ANIMATION_Blinzeln-%2B-AUGENBEWEGUNG-%2B-TEXT_%2880-72%2C12-2%29_9-19%2C-8-12-0%2C5_-GIF.gif d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c95/1529869348309/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che+und+Dr%C3%BCsen+mit+Becherzellen%2C+Ocular+Surface+and+Glands+with+Goblett+Cells_20_.jpg d-Information-2-Complaints https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f0dcfea9716383665d15c9e/1580040619967/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg d-Information-2-Complaints Die Meibom-Öldrüsen in den Augenlidern bilden normalerweise (links) Öl für den Tränenfilm, das die Verdunstung des Tränenwassers hemmt. 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(Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c56e/5f2c56bebc008a542825c571/1582145319697/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Contact%2BLenses%2C%2Bfiting%2Band%2Bcontrol_Kontaktlinsen%2C%2BANPASSUNG%2Bund%2BNACHKONTROLLE_10%2BLINK%2BBILDCHEN_+%281%29.jpg d-essentials-GLIMPSE - PASST &amp; SITZT ... Kontrolle ist besser ;-) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c56e/5f2c56bebc008a542825c56f/1582144297600/OSCB-GIF_KL%2BWeich_OSCB%2BTEXT_LIDER%2B%28FRONTAL%29%2BANIMATION%2BBLINZELN_%2B%2B%2BKONTAKTLINSE%2BWEICHE%2BCorneoscleral%2BFESTER%2B%2880-72%29_8-12-0%2C2%2BGIF%2B2x8Bit_NEU-9-19_KLEIN-LINK-ANIMATION_%2B%281%29.gif d-essentials-GLIMPSE - KONTAKTLINSEN SCHWIMMEN (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c583/1582218717971/OSCB-GIF_Augenoberfl%C3%A4che-ANIMATION_Blinzeln-%2B-AUGENBEWEGUNG-%2BKONTAKTLINSE-%2B-TEXT_%288%2C11-1.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c50a/1595261403959/Tr%C3%A4nentropfen%2C+dunkler+mit+Partikeln+2_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c513/1580329301555/OSCB-Berlin.org%2C+%28c%29+ENK_Augenoberfl%C3%A4che+mit+Meibomdr%C3%BCsen+%2B+%C3%96l-Tropfen+%28Schema+auf+Foto%29+_20_.jpg d-essentials-GLIMPSE Die Meibomdrüsen in den Augenlidern produzieren Öl für den Tränenfilm https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c5a1/1580329301613/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease%2C+Contact+Lenses_Trockenes+Auge_EINMAL+KONTAKTLINSEN%2C+TAGESLINSEN_20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c56c/1509125946475/ d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c503/1580329301552/OSCB-Berlin.org_%28c%29-ENK--Erich-and-Nadja-Knop_AUGENOBERFL%C3%84CHE-%26-TR%C3%84NEN%2C-ANIMATION-NEU_20-8-2_.gif d-essentials-GLIMPSE 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d-essentials-GLIMPSE - KONTAKTLINSEN (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c4eb/5f2c56bebc008a542825c4ee/1596742051089/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES+AUGE_Beispiel+Foto_.jpg d-essentials-GLIMPSE - Augenoberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c4eb/5f2c56bebc008a542825c4ec/1596742098270/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_TROCKENES+AUGE_Beispiel+Foto_.jpg d-essentials-GLIMPSE - Trockenes Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c4eb/5f2c56bebc008a542825c4fc/1596742158811/OSCB-Berlin.org%2C+%28c%29+ENK_RISIKO-Faktoren_Neu+Kombi_.jpg d-essentials-GLIMPSE - Risiko-Faktoren https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c4eb/5f2c56bebc008a542825c4f8/1596742135942/OSCB-GIF_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT-_20-72_2-1fps_%C3%9CBERARBEITET-%2B-GELBER-ZETTEL_10-3-1%2C5_.gif d-essentials-GLIMPSE - Öl-Mangel https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c589/1580329301595/OSCB-Berlin.org_Sklerale-Kontaktlinsen-reichen-bis-weit-in-den-Fornix_ALS+JPG+OHNE+Text+20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c53e/1580329301575/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c57d/1580329301589/OSCB-Berlin.org_%28c%29ENK_Trockenes+Auge%2C+Dry+Eye+Disease%2C+Contact+Lens%2C+Kontaktlinse_OPTISCHE+VORTEILE+der+Kontaktlinse_OHNE+Text_20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c532/1596188913362/GIF-ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_EINZELBILDER%2C-DEUTSCH_33-10-0%2C8_ORIG-DOPP---OHNE-TEXT_.gif d-essentials-GLIMPSE Wenn das Tränenwasser verdunstet (blaue gewellte Pfeile), bleiben die Salze und Proteine (graue Kreise in der Flüssigkeit) zurück und verursachen eine konzentriertere "salzige" Zusammensetzung der verbleibenden Tränen, die als "Hyperosmolarität" bezeichnet wird. Hyperosmolarität, ähnlich wie erhöhte mechanische Reibung, reizt das Augengewebe und die Zellen. Dies führt bei der Erkrankung des trockenen Auges zu Schäden und Entzündungen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c566/1521226543182/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_600pix-8-2%2C5.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c52c/1526802388733/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28AUS%3B+hier+hell+%2B+kontrastreich%29+WEICH+30++%2B+S%C3%A4ttigung_TROCKENES+AUGE%2C+DRY+EYE%2C+W%C3%9CSTE+KAMELE.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c538/1580329301573/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG_20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c563/1522600112541/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_WEB-20_.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c580/1580329301592/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Augenoberfl%C3%A4che+und+KONTAKTLINSE_20+OHNE+Text_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c58f/1580329301601/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Chronisch-Mechanische-Irritation-Epithelzellver%C3%A4nderungen-%28Plattenepithel-Metaplasie%29-der-Bulb%C3%A4ren-Konjunktiva.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c5a4/1567176469807/ARZT-Symbol+%28GR%C3%9CN%29_%C3%9Cberarbeitet+3R+KLEIN.png d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c541/1580329301578/OSCB-Berlin.org_%28c%29+ENK-+Erich+and+Nadja+Knop_Dry+Eye+Disease%2C+Trockenes+Auge_Meibomdr%C3%BCsen+Dysfunktion+%28MDD%2C+MGD%29+mit+verstopften+und+irregul%C3%A4ren+%C3%96ffnungen+eingedicktes+Sekret+wird+ausgepresst_20_.jpg d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c58c/1580329301598/OSCB-Berlin.org_KONTAKTLINSEN---Anpassung-und-Typen_.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c535/1567176469798/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_400-3-0%2C5_.gif d-essentials-GLIMPSE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c557/5f2c56bebc008a542825c55e/1582142827602/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_%2B%281%29.gif d-essentials-GLIMPSE - Lidrand HYGIENE (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c557/5f2c56bebc008a542825c55c/1582142769898/OSCB-Berlin.org%2B%28c%29-ENK_Physical%2BTherapy%2B-%2BLID%2BMASSAGE_10_.jpg d-essentials-GLIMPSE - Lid MASSAGE (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c557/5f2c56bebc008a542825c55a/1582142763351/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_%2B%281%29.gif d-essentials-GLIMPSE - AugenLid WÄRMUNG (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f2c56bebc008a542825c557/5f2c56bebc008a542825c558/1582142757027/OSCB-Berlin.org%2B%28c%29-ENK_TEAR%2BSUBSTITUES%2C%2BTR%C3%84NENERSATZMITTEL%2C%2BSchemabild_10%2BLINK%2BBILDCHEN_.jpg d-essentials-GLIMPSE - TRÄNENERSATZMITTEL (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2c56bebc008a542825c529/1580329301564/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-3D-%C3%96L-RUND_+%281%29.gif d-essentials-GLIMPSE https://oscb-berlin.org/d-essentials daily 0.75 2021-07-10 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85e2111ecb715bf486928a/1602686150312/Animation-OFFICE-EYE_10-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_+%281%29.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2e63d60fe05d162d2e7073/1601285809091/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Glands%2Bof%2Bthe%2BOcular%2BSurface%2C%2BTr%C3%A4nendr%C3%BCsen%2Bder%2BAugenoberfl%C3%A4che_RE-Montage_Neu_30_.jpg Das WICHTIGSTE erklärt - Essentials Drüsen des Auges: Die Tränendrüse liegt seitlich oben hinter dem Oberlid und kleine akzessorische Hilftränendrüsen sind verteilt im Lidgewebe. Becherzellen, die das wichtige Muzin zur Wasserbindung und Benetzbarkeit des Auges bilden, sind als einzelne Zellen (rosa Punkte) eingestreut in die Bindehaut. Die Meibomdrüsen bilden einzelne lange Stränge in beiden Augenlidern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2bea94/1605094110477/GIF_BLINZELN%2C-BLINK-Animation-%28NUR-QUER%29_von+2.2+auf+0%2C14MB_5-25-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Schematische Darstellung der Augenoberfläche im Querschnitt. Der Lidschlag breitet die Tränenflüssigkeit auf dem Auge zum dünnen Tränen-Film aus. Störungen des regelrechten Lidschlages sind also ein typischer Grund für Störungen des Tränen-Film und damit für ein Trockenes Auge ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2beab5/1580040619975/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung_Animation--DEUTSCH-600-2-0%2C5_NEU-anderes-Bild_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbd8100dc9114588643d278/1606255469185/OSCB--Berlin.org-%28c%29-ENK_SCHMERZ-ZONEN-bei-Trockenem-Auge_Zeichnung-KOPF-mit-AUGE-und-WIMPERN%2C-schr%C3%A4g-von-links_10-5-1%2C5.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2bea9d/1602682076752/Henrik+SJ%C3%96GREN_Download.jpg Das WICHTIGSTE erklärt - Essentials Henrik SJÖGREN, schwedischer Augenarzt, der als erster die nach ihm benannte entzündliche Erkrankung der Tränen- und Speicheldrüsen beschrieben hat, die zum Sicca Syndrom von Auge und Mund führt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5bb7026ce2747bd62f481b/1607508840452/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2C%2B_Trockenes%2BAuge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C%2BGewebe%2BReizung_NEU_OHNE%2BText+%2BFlammen_10_.jpg Das WICHTIGSTE erklärt - Essentials Wenn der Tränenfilm auf dem Auge einen ´Aufbruch´ oder ´Riss´ bekommt, werden die Zellen der Augenoberfläche trocken. Solch eine trockene Stelle führt zu Reizung und Brennen am Auge. => die Entwicklung solch eines Trocknen Flecks, wie hier gezeigt, sowie die nachfolgende Schädigung des unterliegenden Gewebes wird weiter unten in einer animierten Abbildung gezeigt. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85e148674be97a6b4cc4bf/1602686150308/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_7-11-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Abstehen bzw. Auswärts-Rollung (Ektropium) des Lidrandes kann zu feuchtem Auge mit Tränenträufeln führen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5ca84bc7f1b136144a8e84/1601285809064/OSCB-Berlin.org%2C+%28c%29+ENK_FOTO+Chronische+Lidentz%C3%BCndung+BLEPHARITIS%2C+Chronic+Lid+Inflammation%2C+Blepharitis_10_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f423c9b0f73c2195e025452/1601285809097/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Augenoberfl%C3%A4che%2Bmit%2BMeibomdr%C3%BCsen%2B%2B%2B%C3%96l-Tropfen%2B%28Schema%2Bauf%2BFoto%29%2B_15_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2beab2/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2e6dc9547ed136f940d172/1606816764820/OSCB-Berlin.org-%28c%29_Animation-BLINZELN-BLINK-%28QUER%2BFRONTAL%29_1-7_TR%C3%84NENFLUSS%2BABFLUSS%2BDRAINAGE_10-25-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Der Lidschlag breitet die Tränenflüssigkeit zum Tränenfilm aus in der Lidspalte. Die Tränenflüssigkeit fliesst hinter dem Lid und im Tränensee (Tränenmeniskus, an der Kontaktstelle zwischen Lidkante und Augapfel).von Unter- und Oberlid. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85dd55a782b87e8afd1eb4/1605172728208/OSCB-Berlin.org%2B%28c%29%2BENK_ABLAGERUNGEN%2Bauf%2Bdem%2BLidrand_ANIMATION%2BEINZELBILD%2Bdaraus%2B2_15_.jpg Das WICHTIGSTE erklärt - Essentials Der Rand eines Augenlids ist hier im schematischen Querschnitt dargestellt. Auf dem Lidrand mit den Wimpern befinden sich gelblich-braune Ablagerungen von Öl-, Staub- und Tränenresten. Dies ist ein typischer Grund für das Gefühl von schleimigen, verklebten Augen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5b30ceb85d91734c9f72f7/1605102543480/Animation_Schema-Gewebeschaden%2C-Reizung%2C-Entz%C3%BCndung-3-%28Vitalf%C3%A4rbung-unauff%C3%A4lliger-%2B-weniger-R%C3%B6tung%29_10-9-0%2C7_.gif Das WICHTIGSTE erklärt - Essentials Die Augenrötung wird durch eine chronische Reizung der Augenoberfläche verursacht, die hauptsächlich auf eine erhöhte Reibung zurückzuführen ist. Mikroverletzungen der Zelloberfläche sind hier als grüne Anfärbung verwundeter Zellen zu sehen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85df50bf823b40496c31fb/1602686150288/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_10_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f8745fbf6477873daf81a90/1604429233077/OSCB-Berlin.org_%28c%29+ENK_LIDER-%28FRONTAL%29-Animation%2C+BLINZELN_%2BTr%C3%A4nenfluss-mit-Gelbem-Zettel_FEUCHTES-Auge%2C-Epiphora_10-10-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Paradoxes ´feuchtes´ Trockenes Auge durch überschiessende Reflex-Tränenbildung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f970a3096c7b33a7bdadbe0/1604429233081/OSCB-Berlin.org_-%28c%29-ENK%2C-GIF-Animation-GRUNDLEGENDE-FUNKTIONELLE-KOMPLEXE-DEUTSCH_Einzel-BILDER_15-11-2_NEU-2_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f30263ff5f70e0fb71e6fbf/1602681837994/OSCB-Berlin.org_Nur-eine-FEUCHTE-Hornhaut-ist-TRANSPARENT_WEB_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5cc28ac7f1b136144c40e5/1601287974647/OSCB-Berlin_%C2%A9-ENK_UNSCHARF-SEHEN---do-you-also-suffer-%2B-BLINK%2C-Blinzeln_4_10-17-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Sehstörungen beim Trockenen Auge werden typischerweise nach einem Lidschlag besser - aber nur vorübergehend. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f4d44af24f750188c56aedb/1602682013878/OSCB-Berlin.org_Aufbau+des+Tr%C3%A4nen+FILMs+mit+der+LIPID+SCHICHT+%28TFLS%29+auf+dem+w%C3%A4ssrigen+Tr%C3%A4nenfilm_20_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa1b0daea83c4327e1fa87e/1604667792416/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____RISIKO+FAKTOREN%2C+internal+and+external+RISK+FACTORS_15_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2beaac/1599813773645/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85dddfc4865d07b824e942/1602686150271/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT%2Bdes%2BTrockenen%2BAuges%2C%2BFrequency%2Bof%2BDry%2BEye%2BDisease_10_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85de8099b9055c32681605/1602686150267/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_7-3-0%2C5_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f32bd4486fc657564dcb7cc/1602682097106/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Dry%2BEye%2BDisease%2C%2BTrockenes%2BAuge_Meibomdr%C3%BCsen%2BDysfunktion%2B%28MDD%2C%2BMGD%29%2Bmit%2Bverstopften%2Bund%2Birregul%C3%A4ren%2B%C3%96ffnungen%2Beingedicktes%2BSekret%2Bwird%2Bausgepresst_20_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f71ee1d16f8f61891ac894e/1602686150278/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_10-15-0%2C3.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f32cde08b7b6411cc65a45c/1605293021994/OSCB-GIF_MEIBOM-SECRETION-%2B-DELIVERY_aus-Folien-zur-ANIMATION-etc.-aus-WAKAYAMA-%2B-ISER-2016_HEINRICH-MEIBOM-%28BESSER%29_NEU_KURZ-15-4-0%2C4+%281%29.gif Das WICHTIGSTE erklärt - Essentials Augenlid im Querschnitt (schematisch): Der Lidschlag sorgt für die Auspressung der Meibomdrüsen: Die Meibomdrüsen bilden das Öl durch Haufen von Drüsenzellen in rundlichen Endstücken (”Secretion” links unten in der Abbildung). Die Drüsenzellen liegen tief im Augenlid und füllen das Gangsystem der Drüsen mit öligem Sekret (Pfeile). Durch den leichten Druck der Lidmuskulatur beim Lidschlag werden Öl-Tröpfchen aus der Drüsen-Öffnung am Lidrand herausgedrückt (“Delivery”). => Eine weitere animierte Abbildung zeigt, was passiert wenn die Meibomdrüsen verstopft sind bei Meibomdrüsen Dysfunktion (MDD). https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2beab8/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f71f09dd94ac818ff442b3d/1602686150291/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_15-2-1_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f47c4725a444b08456feeb1/1608375389856/OSCB-Berlin.org+%28c%29+ENK_Evaporation+of+Water+leads+to+HyperOsmolarity+of+the+Tear+Film%2C+Schema_10_.jpg Das WICHTIGSTE erklärt - Essentials Auch bei normaler Produktion wässriger Tränen durch die Tränendrüse (oben links in der Abbildung) kann es bei einem Ölmangel durch Störung der Meibom-Öldrüsen (oben rechts in der Abbildung) in den Augenlidern zu sekundärem Wassermangel im Tränenfilm kommen. Durch Ölmangel erhöht sich die Verdunstung des Tränenwassers und damit die Konzentration der zurückbleibenden Salze und Proteine (graue Kreise in der Abbildung). Dies wird als Hyperosmolarität bezeichnet und kann zu Reizung und Schädigung der Zellen führen. (Schematisch dargestellt in der Abbildung ist das Epithel der Bindehaut mit einer Becherzelle). Bei hyper-osmolarem Tränenfilm können hypo-osmolare Tränenersatzmittel nützlich sein zur Verdünnung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fd372c5590d9171f96d4ba3/1607693010203/OSCB-Berlin.org+%28c%29+ENK_GIF-Animation-GRUNDLEGENDE-KAUSALE-FAKTOREN-f%C3%BCr-das-TROCKENE-AUGE_DEUTSCH_Einzel-BILDER_400pix-32-2_.gif Das WICHTIGSTE erklärt - Essentials Grundlegende kausale Faktoren führen typischerweise zu einem Trockenen Auge und daraus kann ein degenerativer Gewebeumbau entstehen wenn es chronisch wird. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb53d3b91b3964dacea1579/1605713227917/Augenoberfl%C3%A4che+mit+Hornhaut+als+BANNER+f%C3%BCr+EyeCare_3_20-72_2+%2B+Tropfen_Zettel_kurz_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85db222c939c5241fb08a2/1602686150298/OSCB-Berlin.org_Nur-der-d%C3%BCnne-homogene-Tr%C3%A4nen-FILM-garantiert-GESUNDHEIT-und-scharfes-SEHEN---Einfach-3D-%C3%96L-RUND_14-5-1_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb5286c6de2705a8fe1c684/1605785180887/Therapy+Options%2C+Therapie+Optionen+DEUTSCH_Mild-Moderate-Severe_%C3%9Cbersicht_20_.jpg Das WICHTIGSTE erklärt - Essentials Schema der Stufen-Therapie für das Trockene Auge https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f8321c5f2adc66c169d8759/1602686150301/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_15_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faec42f16947a58fedf4f0f/1605293645857/OSCB-Berlin.org-%28c%29-ENK_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT_MONTAGE-%2B-LidRAND_10-5-1%2C5_.gif Das WICHTIGSTE erklärt - Essentials Ein schematischer Querschnitt durch ein Unterlid zeigt die Folgen der Verstopfung der Meibomdrüsen (Tränenfilm-Mangel und verborgene Drüsenschädigung im Lid) - (Zur Orientierung, vergleichen Sie bitte diese Abbildung des Lidrandes) - Der Mechanismus der Ölproduktion in den Meibomdrüsen wird gezeigt in folgender Abbildung) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70dff2b66cd43eed734e2e/1607691043341/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_+%281%29.gif Das WICHTIGSTE erklärt - Essentials Eine Störung des Tränenfilms schädigt das Gewebe der Augenoberfläche => hier finden Sie eine genauerer Darstellung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70d412b66cd43eed71b5c3/1601285809080/OSCB-Berlin.org_%28c%29-ENK--Erich-and-Nadja-Knop_AUGENOBERFL%C3%84CHE-%26-TR%C3%84NEN%2C-ANIMATION-NEU_10-8-2_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f47fd4f276e36026f01dd36/1604830756188/OSCB-Berlin.org_FEINSTRUKTUR-der-AUGENOBERFL%C3%84CHE-und-TR%C3%84NENFILM+%2B+PSE+AUSSCHNITT+Mikrovilli+u.+Muzin_20_.jpg Das WICHTIGSTE erklärt - Essentials Schematisch dargestellt sind hier die Epithelzellen der Bindehaut mit einer Becherzelle. Die Muzin-Schleimstoffe in der Becherzelle und im Tränenfilm sind in rosa Farbe markiert, entsprechend einer bekannten histologischen Färbung ;-). Erkennbar sind auch die feinen Finger-artigen Zellfortsätze (Mikrovilli), die die Oberfläche vergrössern und so die Benetzbarkeit verbessern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f5b4e5f73705f23eb03252f/1607691048506/OSCB-Berlin.org_%28c%29+ENK_GIF-ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_%28GEK%C3%9CRZT-4_400-11-0%2C7%29.gif Das WICHTIGSTE erklärt - Essentials Störungen des dünnen Tränenfilms führen zur Beschädigung der Gewebeoberfläche mit Verminderung der Benetzbarkeit. Chronische Gewebeschäden können zu einem degenerativen Gewebeumbau führen => dies wird gezeigt in einer detailreicheren Animation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2e64f6bb50dc46823ebdc6/1602681933047/Tr%C3%A4nentropfen%2C+dunkler+mit+Partikeln+2_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85e10d862a6b276cb6fabc/1602686150305/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_300-10-0%2C2__.gif Das WICHTIGSTE erklärt - Essentials Bei inkomplettem Lidschlag wird der untere Teil des Tränenfilms nicht erneuert und das Gewebe in diesem Bereich nicht ausreichend befeuchtet. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f624f1b1c1b4d0f2c5684bd/1608378087566/ESSENTIALS%2C+Link-Bildchen+in+EINEM+Bild+2.jpg Das WICHTIGSTE erklärt - Essentials zu Fragen & Antworten: =>Fakten =>Beschwerden =>Risikofaktoren =>Ursache =>Trockenheit =>Schaden =>Verschlimmerung =>Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2d4b7d57a9c73e3e2beaa0/1606834196365/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg Das WICHTIGSTE erklärt - Essentials Die Meibom-Öldrüsen in den Augenlidern bilden normalerweise (links im Bild) Öl für den Tränenfilm, das die Verdunstung des Tränenwassers hemmt. Wenn die Öldrüsen blockiert sind (mittlerer Teil des Bildes), tritt kein Öl aus und somit verdunstet das Tränenwasser schneller. Das Öl bleibt jedoch in den Drüsen stecken und weitet das Gangsystem aus, wodurch das Drüsengewebe geschädigt wird. Wenn die Drüsenverstopfung über längere Zeit bestehen bleibt (rechts im Bild), werden die Drüsen beschädigt durch den erhöhten Druck und erscheinen verkürzt oder fehlen ganz. Dies kann mit der Untersuchungstechnik der Meibographie sichtbar gemacht werden. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f400141c758e526f1fffa65/1601285809072/OSCB-Berlin.org_6_Dry+Eye+Disease_INTERNE+Risiko+Faktoren+f%C3%BCr+Trockenes+Auge_10.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f624a07a9859e677798f146/1602681808216/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f85d9093e9fd13e8c8a4d9f/1605273803437/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che%2Bund%2BDr%C3%BCsen%2Bmit%2BBecherzellen%2C%2BOcular%2BSurface%2Band%2BGlands%2Bwith%2BGoblett%2BCells_15_.jpg Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f2db2fe4724477478414546/1604766026114/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM%2Bohne%2BText_.jpg Das WICHTIGSTE erklärt - Essentials => hier finden Sie eine animierte Darstellung von Lidschlag und Tränenfilm-Ausbreitung https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fcce35eeb18547f4b844fc7/1607263169930/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_10-18-0%2C2_.gif Das WICHTIGSTE erklärt - Essentials Das Aufbrechen des dünnen Tränenfilms wird sichtbar, wenn die Tränen mit dem Fluorescein-Farbstoff angefärbt werden, der im blauen Licht betrachtet wird. Ein Aufbrechen ist sichtbar als dunkler Bereich (hier in der Mitte des "C" vom OSCB-Overlay). Das Aufbrechen des Tränenfilms ist der Stimulus, der einen Lidschlag auslöst, um einen neuen Tränenfilm zu verteilen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70d2a616ffd844a3d51569/1601285809045/GIF%2BAnimation_Typische%2BSymptome%2Bbeim%2BTrockenen%2BAuge_10-5-1%2C0_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc53d884f9837572089dc8a/1606761929393/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5+%281%29_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f6b97508b93427d318b4e89/1605098006087/1_OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg Das WICHTIGSTE erklärt - Essentials Bei starker Trockenheit und Wundheit des Auges kann sich das Gefühl eines ausgedörrten Wüstenbodens, der schmerzhaft aufspringt, einstellen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70d7f10a75e61a51c603db/1601285809074/Animation-OFFICE-EYE_10-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif Das WICHTIGSTE erklärt - Essentials https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70df12abd4ac5b16b2f75a/1601285809148/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_10-12-1%2C0_.gif Das WICHTIGSTE erklärt - Essentials Schematisch dargestellt ist hier das Epithel der Hornhaut https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f78bd84fc210b274560ddc7/1605119571193/OSCB-Berlin.org_%28c%29-ENK_Animation-AugenBewegung%2C-Mechanische-Reibung%2C-Fremdk%C3%B6rpergef%C3%BChl-%2BGranula-%2Bgelber-Zettel_10-12-0%2C5-%2B-R%C3%B6tung-2_.gif Das WICHTIGSTE erklärt - Essentials Tränenmangel beim Trockenen Auge führt typischerweise zu verminderter ´Schmierung´ zwischen Augenlidern und Augapfel mit erhöhter mechanischer Reibung und dem Gefühl von Sandkörnern oder Fremdkörpern auf dem Auge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f70d6391d058032c8aef2dd/1601285809112/OSCB-Berlin.org-%28c%29-ENK_Dry-Eye-Trockenes-Auge%2C-TEAR%2BFILM%2C-Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-15-9-0%2C5.gif Das WICHTIGSTE erklärt - Essentials https://oscb-berlin.org/therapy-steps daily 0.75 2021-07-02 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/605b9e0f143963043aa651e0/1616617626967/STUFEN%2BTHERAPIE%2C%2BVERSCHREIBUNGSPFLICHTIGE%2BARZNEIMITTEL__.jpg Therapie - STUFENTHERAPIE ! - Medikamente https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/605b9dfdd6cb0e22fb16cd87/1616617818637/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_10-12-1%2C3_+%281%29.gif Therapie - STUFENTHERAPIE ! - Punctum Plugs https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/5f7f5deffbfb976f1b862595/1602238776059/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+DICKfl%C3%BCssiges+GEL+zur+NACHT_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - GEL zur Nacht https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/5f7f5deffbfb976f1b862593/1615536226064/IPL-Animation_Intense-Pulsed-Light_%28c%29ENK%2C-www.OSCB-Berlin.org_400-15-1_.gif Therapie - STUFENTHERAPIE ! - Licht-Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/5f7f5deffbfb976f1b862591/1602238785235/lipiflow-animation_8-48-0%2C05_.gif Therapie - STUFENTHERAPIE ! - Lipiflow https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b86258e/5f7f5deffbfb976f1b86258f/1616617112826/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+D%C3%9CNNfl%C3%BCssige+Tropfen+ST%C3%9CNDLICH_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - Tränenersatz, häufig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862599/5f7f5deffbfb976f1b86259c/1602238819783/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+DICKfl%C3%BCssiges+GEL+TAGS+%2B+NACHTS_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - Gel auch tagsüber https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862599/5f7f5deffbfb976f1b86259e/1602238829355/STUFEN+THERAPIE%2C+VERSCHREIBUNGSPFLICHTIGE+ARZNEIMITTEL__.jpg Therapie - STUFENTHERAPIE ! - Medikamente vom Arzt https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862599/5fb80c8d75e1b0193de3a8a6/1616617866235/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_10-12-1%2C3_.gif Therapie - STUFENTHERAPIE ! - Punctum Plugs https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862599/605ba391ab65a464866388be/1616618415660/Animation+sklarale+Linse+%2B+Lidschlag.gif Therapie - STUFENTHERAPIE ! - Sklerale Kontaktlinsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862583/5f7f5deffbfb976f1b862588/1602238738410/OSCB-Berlin.org%2C+%28c%29+ENK_Risikofaktoren+VERMEIDEN_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - Risikofaktoren meiden https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862583/5f7f5deffbfb976f1b862584/1602238728496/OSCB-Berlin.org%2C+%28c%29+ENK_INFO_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - Information https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862583/5f7f5deffbfb976f1b862586/1602238754962/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+D%C3%9CNNfl%C3%BCssige+Tropfen_10+LINK+BILDCHEN_.jpg Therapie - STUFENTHERAPIE ! - Tränenersatz, dünnflüssig https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5f7f5deffbfb976f1b862583/604b53da45aca374cf38af56/1615549486361/Unbenannt-2.jpg Therapie - STUFENTHERAPIE ! - Augenlid Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbe2237e6d49a06bb5a6f23/1606301881970/OSCB-Berlin.org+%28c%29+ENK_TROCKENES+AUGE%2C+Sehr+SCHWER%2C+very+severe+DRY+EYE%2C+BLEPHARITIS_20_.jpg Therapie - STUFENTHERAPIE ! Bild eines sehr schweren Trockenen Auges mit Hornhauttrübungen, Einwachsen von Gefässen auf die Hornhaut, beginnende Konjunktivalisierung; zusätzlich liegt eine chronische Blepharitis vor. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb006052bb93a1ea2cbeda3/1605371413281/Therapy+Options%2C+Therapie+Optionen+DEUTSCH_Mild-Moderate-Severe_%C3%9Cbersicht_40_.jpg Therapie - STUFENTHERAPIE ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f7f5deffbfb976f1b862581/1580155255054/Diagnostik+und+Therapie%2C+Abbildung+f%C3%BCr+LINK+BANNER_3+f%C3%BCr+Erkennen+%26+Behandeln%2C+Patient%2C+Arzt%2C+Fragezeichen%2C+Schlange+%2B+3D+W%C3%9CRFEL+f%C3%BCr+Stufentherapie_.jpg Therapie - STUFENTHERAPIE ! https://oscb-berlin.org/d-nervous-system-blink-pain daily 0.75 2021-07-03 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f972e62c3715116ec8f05ca/1604688214423/Download+%282%29.gif Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f971e6f5d28fd0920342ee1/1604688214405/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2BDisease_Trockenes%2BAuge_NERVENREIZUNG%2Bbei%2BEPITHELSCH%C3%84DIGUNG%2B%2B%2BGEHIRN_20_.jpg Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f971fc7992a9c094621f190/1604688214408/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM_NUR-BLINZELN-9-19_500-16-1_.gif Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fcce9e22fa8bc6bcde99b4f/1607264801726/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_20-18-0%2C2_.gif Nervensystem, Lidschlag und Schmerz Das Aufbrechen des dünnen Tränenfilms wird sichtbar, wenn die Tränen mit dem Fluorescein-Farbstoff angefärbt werden, der im blauen Licht betrachtet wird. Ein Aufbrechen ist sichtbar als dunkler Bereich (hier in der Mitte des "C" vom OSCB-Overlay). Das Aufbrechen des Tränenfilms ist der Stimulus, der einen Lidschlag auslöst, um einen neuen Tränenfilm zu verteilen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f972dd70192002e6dec3621/1604688214420/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29+%282%29.gif Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f973b936a54d17debd72aa5/1604688214411/OSCB-Berlin.org_%28c%29%2BENK_LIDER-%28FRONTAL%29-Animation%2C%2BBLINZELN_%2BTr%C3%A4nenfluss-mit-Gelbem-Zettel_FEUCHTES-Auge%2C-Epiphora_10-10-0%2C2_.gif Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f971d87fcd1705a9b24b3e8/1604688214401/OSCB-Berlin.org_%28c%29ENK_Regulatorische-Systeme-mit-ZETTEL-2_10-2-0%2C5_.gif Nervensystem, Lidschlag und Schmerz https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5f97211986e2dc4fc9d2a4aa/1604688214417/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif Nervensystem, Lidschlag und Schmerz https://oscb-berlin.org/e-essentials daily 0.75 2021-06-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887def9/1605450585973/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-BLINZELN_%2BECTROPION_2-mit-Gelbem-Zettel-%2B-TR%C3%84NEN%2C-langsam_NEU-2-Kurz_7-11-0%2C2_.gif ESSENTIALS for Dry Eyes Protruding or outward rolling (ectropion) of the eyelid margin can lead to moist eyes with tears https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dee4/1602686150301/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye_Trockenes+Auge%2C+TEAR+FILM+DEFICIENCY%2C+AQUEOUS+vs.+LIPID+-+WASSERMANGEL+80%25+-+OHNE+Text_15_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df0e/1580040619975/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung_Animation--DEUTSCH-600-2-0%2C5_NEU-anderes-Bild_.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae896ff8f3f141908cb277/1607181396458/OSCB-Berlin.org-%28c%29-ENK_-Animation-BASIC-FUNCTIONAL-COMPLEXES-ENGLISCH_Einzel-BILDER_Dry-Eye-Disease%2C-Trockenes-Auge_VERBESSERT_400pix-11-1%2C5--%2B-CROP_.gif ESSENTIALS for Dry Eyes Basic functional complexes provide an intact stable tear film for permanent moisture and clear vision. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae813016932f1df5d42cfe/1605271869313/OSCB-Berlin.org-%28c%29-ENK_Animation-TEAR-FLOW-at-the-Ocular-Surface%2C-Tr%C3%A4nen%2C-Functional-Unit__15-2-1_.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc5271e3570fb44d1a87fd0/1606760810983/DEMODEX-Haarmilben_ANIMATION_3-ENGL_Beinchen-600-11-0%2C5+%281%29_.gif ESSENTIALS for Dry Eyes The lid margin is populated by low numbers of harmless normal bacteria and Demodex hair mites. Demodex reside in the hair follicles and are mobile along the lashes. In case of chronic eyelid inflammation (chronic blepharitis), often associated with chronic dry eye disease, the number of demodex and bacteria is increased.=> here is a microscope image of Demodex mites https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df05/1599813773645/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease_Trockenes+Auge_NERVENREIZUNG+bei+EPITHELSCH%C3%84DIGUNG+%2B+GEHIRN_20_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dea8/1602681808216/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Eye%2BDrops%2Bcan%2BDAMAGE%2Bthe%2BOcular%2BSurface_20_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de9f/1605270057133/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____RISIKO+FAKTOREN%2C+internal+and+external+RISK+FACTORS_15_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df02/1607026796131/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-ohne-VC_635-7-1%2C0_+%281%29.gif ESSENTIALS for Dry Eyes A disruption of the tear film damages the tissue of the surface of the eye => here you will find a more detailed description https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dec9/1605292943750/OSCB-GIF_MEIBOM-SECRETION-%2B-DELIVERY_aus-Folien-zur-ANIMATION-etc.-aus-WAKAYAMA-%2B-ISER-2016_HEINRICH-MEIBOM-%28BESSER%29_NEU_KURZ-15-4-0%2C4+%281%29.gif ESSENTIALS for Dry Eyes Cross-section of the eyelid (schematic): The eyelid blink ensures that the meibomian glands are expressed: The Meibomian glands produce the oil through clusters of gland cells in rounded end pieces ("Secretion", bottom left in the figure). The gland cells lie deep in the eyelid and fill the duct system of the glands with oily secretions (arrows). The slight pressure of the eyelid musculature during the eyelid blink pushes oil droplets out of the gland opening on the edge of the eyelid (“Delivery”). => Another animated figure shows what happens when the glands are blocked in Meibomian gland dysfunction. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dec6/1606816797541/OSCB-Berlin.org-%28c%29_Animation-BLINZELN-BLINK-%28QUER%2BFRONTAL%29_1-7_TR%C3%84NENFLUSS%2BABFLUSS%2BDRAINAGE_10-25-0%2C2_.gif ESSENTIALS for Dry Eyes The eyelid blink spreads the tear fluid into the tear film within the interpalpebral fissure. The tear fluid flows behind the lid and in the tear lake (tear strip/ tear meniscus - is located at the contact point between the inner lid margin and the eyeball. It is present at both the lower and upper eyelids. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887deea/1607690471927/OSCB-Berlin.org_%28c%29+ENK_GIF-ANIMATION_%C3%96L-MANGEL-im-Tr%C3%A4nenfilm-f%C3%BChrt-zu-VERDUNSTUNG-etc_%28GEK%C3%9CRZT-4_400-11-0%2C7%29.gif ESSENTIALS for Dry Eyes Disturbances of the thin tear film lead to damage to the tissue surface with a reduction in wettability. Chronic tissue damage can induce a degenerative tissue remodelling => as shown in a more detailed animation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df08/1601285809148/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC_10-12-1%2C0_.gif ESSENTIALS for Dry Eyes The epithelium of the cornea is shown schematically here https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de78/1602686150267/Animation_www.OSCB-Berlin.org%2C-%C2%A9--Erich-and-Nadja-KNOP---ENK--_Rotes-TROCKENES-AUGE%2C-Red-DRY-EYE_7-3-0%2C5_.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dec0/1602681933047/Tr%C3%A4nentropfen%2C+dunkler+mit+Partikeln+2_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5669b9c6d802994413c1a/1604675239456/GIF-Animation_TYPICAL-SYMPTOMS-in-DRY-EYE-DISEASE_Typische-Symptome-beim-Trockenen-Auge_Bild-ENGLISCH-1-4v4_KURZ_10-72_5-1%2C5_+%281%29.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae7f0716947a58fed30282/1605271462731/OSCB-Berlin.org+%28c%29+ENK_Glands+of+the+Ocular+Surface%2C+Tr%C3%A4nendr%C3%BCsen+der+Augenoberfl%C3%A4che_RE-Montage_15_.jpg ESSENTIALS for Dry Eyes Glands of the ocular surface: The lacrimal gland lies in the lateral upper part behind the upper eyelid and small accessory tear glands (Krause & Wolfring) are distributed along the eyelid tissue. Goblet cells, which produce the important mucin for water binding and wettability of the eye, are scattered as single cells (pink dots) along the conjunctiva. The Meibomian glands form individual long strands inside both eyelids. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de90/1605172767590/OSCB-Berlin.org%2B%28c%29%2BENK_ABLAGERUNGEN%2Bauf%2Bdem%2BLidrand_ANIMATION%2BEINZELBILD%2Bdaraus%2B2_15_.jpg ESSENTIALS for Dry Eyes The edge of an eyelid is shown here in schematic cross section. On the lid margin with the eye lashes are yellowish brown deposits of oil, dust and tear remnants. This is a typical reason for the sensation of slimy, sticky and clotted eyes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae803b844f9e409e502a0d/1605271726812/OSCB-Berlin.org+%28c%29+ENK+_FINE+STRUCTURE+of+the+OCULAR+SURFACE+and+TEAR+FILM_20_.jpg ESSENTIALS for Dry Eyes The epithelial cells of the conjunctiva with a interspersed goblet cell are shown schematically here. The mucins in the goblet cell and in the tear film are marked in pink, corresponding to a well-known histological stain ;-). The fine finger-like cell extensions (microvilli) enlarge the surface and thus improve the wettability. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de75/1605804834561/ESSENTIALS%2C+Link-Bildchen+in+EINEM+Bild+2.jpg ESSENTIALS for Dry Eyes to questions & answers: => facts => complaints => risk factors => cause => dryness => damage => aggravation => therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae7ddc4aff1f2f851073a4/1605271046678/OSCB-Berlin.org+%28c%29+ENK%29_3.1.6_Only+a+MOIST+Cornea+can+stay+TRANSPARENT_20+OT_.jpg ESSENTIALS for Dry Eyes Only a moist cornea is transparent. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df11/1529244871760/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Some-THERAPY-OPTIONS-in-DRY-EYE-DISEASE_ohne+Text_10+LINK+BILDCHEN_START2_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887deff/1602686150312/Animation-OFFICE-EYE_10-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_+%281%29.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb53e1b63f4ad0a6b1cd6d8/1605713447271/Augenoberfl%C3%A4che+mit+Hornhaut+als+BANNER+f%C3%BCr+EyeCare_3_20-72_2+%2B+Tropfen_Zettel_kurz_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887ded8/1605273953105/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___Augenoberfl%C3%A4che%2Bund%2BDr%C3%BCsen%2Bmit%2BBecherzellen%2C%2BOcular%2BSurface%2Band%2BGlands%2Bwith%2BGoblett%2BCells_15_.jpg ESSENTIALS for Dry Eyes Ocular glands produce the tear fluid and the eyelids spread it into the tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae8b10c2244972c64b1799/1607690210281/OSCB-Berlin.org-%28c%29-ENK_Animation-BASIC-CAUSATIVE-FACTORS-for-Dry-Eye-Disease_Dry-Eye-Disease%2C-Trockenes-Auge_300pix-30-2_.gif ESSENTIALS for Dry Eyes Basic causative factors typically result in Dry Eye Disease and this can lead to a degenerative remodelling of the tissue it becomes chronic https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887def0/1606834263625/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg ESSENTIALS for Dry Eyes The meibomian oil glands in the eyelids normally (left side of the image) produce oil for the tear film, which retards the evaporation of the tear water. When the oil glands are blocked (middle part of the image) no oil comes out and thus the tear water evaporates faster. The oil however, is stuck inside the glands and dilates the ductal system causing gland tissue damage. When the gland obstruction persists for a prolonged time (on the right side in the image), the glands are damaged by the increased pressure and appear shortened or lost. This can be analysed with the diagnostic technique of meibography. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fcce174d336b863f0c201e7/1607262685151/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_10-18-0%2C2_.gif ESSENTIALS for Dry Eyes The break-up of the thin tear film becomes visible when the tears are stained with the fluorescein dye that is observed in blue light. A break-up occurs as a dark area (seen here in the middle of the faint “C” of the OSCB overlay). The break-up of the tear film is the stimulus that triggers an eyelid blink in order to distribute a new tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de8a/1605457521859/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2C%2B_Trockenes%2BAuge_Evaporation%2BVerdunstung%2C%2BHyperosmolarity%2C%2BHyperosmolarit%C3%A4t%2C%2B%C3%96l%2BMangel%2C%2BOil%2BDeficiency%2C%2BTrockenes%2BAuge%2BDry%2BEye%2BDisease%2C%2BGewebe%2BReizung_NEU_OHNE%2BText+%2BFlammen_10_.jpg ESSENTIALS for Dry Eyes When the tear film on the eye breaks-up ´the cells of the surface of the eye become dry. Such a dry spot causes irritation and burning or stinging of the eye. => the development of a dry spot, as seen here, and the subsequent damage to the underlying tissue, is shown in an animated figure further down. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de9c/1602686150288/OSCB-Berlin.org_%28c%29%2BENK-%2BErich%2Band%2BNadja%2BKnop_Contact%2BLenses%2C%2BKontaktlinsen_Trockenes%2BAuge%2C%2BROTES%2BAUGE%2C%2BKonjunktivale%2BInjektion%2Bmit%2Bweicher%2BKONTAKTLINSE_10_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae84e31c7089551ac6e943/1605272938594/OSCB-Berlin.org-%28c%29-ENK_Animation_ONLY-A-THIN-HOMOGENEOUS-TEAR-FILM-guarantees-HEALTH-and-clear-VISION_8-2_15-8-2_.gif ESSENTIALS for Dry Eyes Only the thin homogeneous tear film guarantees health and clear vision https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbd852485bfa9327b1558c1/1606256056218/OSCB--Berlin.org-%28c%29-ENK_SCHMERZ-ZONEN-bei-Trockenem-Auge_Zeichnung-KOPF-mit-AUGE-und-WIMPERN%2C-schr%C3%A4g-von-links_10-5-1%2C5.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887defc/1606310809249/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_300-10-0%2C2__.gif ESSENTIALS for Dry Eyes If the eyelid blink is incomplete , the lower part of the tear film is not renewed and the tissue in this area is not sufficiently moistened. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887deb4/1605098845261/GIF_BLINZELN%2C-BLINK-Animation-%28NUR-QUER%29_von+2.2+auf+0%2C14MB_5-25-0%2C2_.gif ESSENTIALS for Dry Eyes Schematic representation of the ocular surface n cross section. The eyelid blink distributes the tear fluid on the eye into a thin homogeneous tear film. Disturbances of the regular eyelid blinking are therefore a typical reason for disturbances of the tear film and thus for a dry eye ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae83b236358572f1222006/1605272510963/OSCB-Berlin.org+%28c%29+ENK_Bild_4_Tears+%26+Tear+Film_Structure+of+the+Tear+FILM+with+the+Tear+Film+LIPID+LAYER+%28TFLL%29%2C+aus+Ophthalmologe+2003_15_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de7b/1602686150271/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse___H%C3%84UFIGKEIT%2Bdes%2BTrockenen%2BAuges%2C%2BFrequency%2Bof%2BDry%2BEye%2BDisease_10_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de93/1601285809064/OSCB-Berlin.org%2C+%28c%29+ENK_FOTO+Chronische+Lidentz%C3%BCndung+BLEPHARITIS%2C+Chronic+Lid+Inflammation%2C+Blepharitis_10_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887debd/1604771601592/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Augenoberfl%C3%A4che%2Bmit%2BMeibomdr%C3%BCsen%2B%2B%2B%C3%96l-Tropfen%2B%28Schema%2Bauf%2BFoto%29%2B_15_.jpg ESSENTIALS for Dry Eyes Every single gland of the about 50 Meibomian glands that occur in an eye (shown here as yellow streaks) can release a little drop of oil onto the lid margin and tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887deed/1602682076752/Henrik+SJ%C3%96GREN_Download.jpg ESSENTIALS for Dry Eyes Henrik SJÖGREN, Swedish ophthalmologist, who was the first to describe the inflammatory disease of the tear and salivary glands named after him, which leads to the sicca syndrome of the eyes and mouth. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de99/1604429233077/OSCB-Berlin.org_%28c%29+ENK_LIDER-%28FRONTAL%29-Animation%2C+BLINZELN_%2BTr%C3%A4nenfluss-mit-Gelbem-Zettel_FEUCHTES-Auge%2C-Epiphora_10-10-0%2C2_.gif ESSENTIALS for Dry Eyes Paradoxical ' wet' dry eye due to excessive reflex tear formation https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faebe8d9d560157707b3919/1605293655959/OSCB-Berlin.org-%28c%29-ENK_MEIBOMDR%C3%9CSE%2C-Normal-%2B-Obstruktion-%28Ophthalmologe-2009%29_AUFRECHT_MONTAGE-%2B-LidRAND_10-5-1%2C5_.gif ESSENTIALS for Dry Eyes Obstruction of the Meibomian glands leads first to tear film deficiency at the surface and later to dilatation and destruction of the gland tissue inside the eyelids. (For orientation, please compare with this figure of the eyelid margin) - For the secretory mechanism of the Meibomian glands please see this image) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dee7/1608375649620/OSCB-Berlin.org+%28c%29+ENK_Evaporation+of+Water+leads+to+HyperOsmolarity+of+the+Tear+Film%2C+Schema_10_.jpg ESSENTIALS for Dry Eyes Even with normal production of watery tears by the lacrimal gland (upper left in the image), a lack of oil can lead to a secondary lack of water in the tear film due to dysfunction of the meibomian oil glands (upper right in the image) inside the eyelids. A lack of oil increases the evaporation of the tear water and thus the concentration of the remaining salts and proteins (gray circles in the image). This is known as hyperosmolarity and it can cause irritation and damage to cells that trigger inflammation. (The epithelium of the conjunctiva with a goblet cell is shown schematically here in the image). Hypo-osmolar aqueous tear supplements can be useful to dilute a hyper-osmolar tear film in evaporative dry eyes. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de8d/1602686150278/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_10-15-0%2C3.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887decf/1604766211054/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__TR%C3%84NENFILM%2Bohne%2BText_.jpg ESSENTIALS for Dry Eyes => here you can find an animated figure of the distribution of tears into the tear film by the eyelid blink https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb4f24149f13c3a243a9f33/1605714385583/Therapy+Options+ENGLISCH_Mild-Moderate-Severe_%C3%9Cbersicht_20_.jpg ESSENTIALS for Dry Eyes => Staggered therapy for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de84/1605119559802/OSCB-Berlin.org_%28c%29-ENK_Animation-AugenBewegung%2C-Mechanische-Reibung%2C-Fremdk%C3%B6rpergef%C3%BChl-%2BGranula-%2Bgelber-Zettel_10-12-0%2C5-%2B-R%C3%B6tung-2_.gif ESSENTIALS for Dry Eyes A lack of tears in dry eyes typically typically causes reduced lubrication between eyelids and eyeball with thus increased mechanical friction that causes gritty sandy feeling and foreign body sensation. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae7a0f4cb72305414e62a3/1605270043076/OSCB-Berlin.org_6_Dry-Eye-Disease_INTERNAL--RISK-FACTORS--for-Dry-Eye-Disease_NEU-quadratisch-2_15_.jpg ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae8cea9488406ed9a7460d/1605274920696/OSCB-Berlin.org_%28c%29%2BENK_Dry%2BEye%2BDisease%2C%2BTrockenes%2BAuge_Meibomdr%C3%BCsen%2BDysfunktion%2B%28MDD%2C%2BMGD%29%2Bmit%2Bverstopften%2Bund%2Birregul%C3%A4ren%2B%C3%96ffnungen%2Beingedicktes%2BSekret%2Bwird%2Bausgepresst_20_OT_.jpg ESSENTIALS for Dry Eyes Blocked Meibomian oil glands with inspissated secretum. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887df0b/1529869348317/VICIOUS-CIRCLE-VEREINFACHT%2C-%28ohne-Entz%C3%BCndung%29-2-NEU-OHNE-TITEL__Entwicklung-PRIMARY-PATHOLOGIES-%2B-VC%2BENTZ%C3%9CNDUNG_635-2-0%2C2_.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de87/1605120410464/Animation_Schema-Gewebeschaden%2C-Reizung%2C-Entz%C3%BCndung-3-%28Vitalf%C3%A4rbung-unauff%C3%A4lliger-%2B-weniger-R%C3%B6tung%29_10-9-0%2C7_.gif ESSENTIALS for Dry Eyes Eye redness is caused by the chronic irritation of the ocular surface, mainly due to increased friction. Micro-injuries of the cell surface are seen here as green spots of wounded cells. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887decc/1607023822939/OSCB-Berlin.org-%28c%29-ENK_Dry-Eye-Trockenes-Auge%2C-TEAR%2BFILM%2C-Tr%C3%A4nenfilm-AQUARIUM-AUF-ZETTEL-montiert%2C-15-9-0%2C5.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de96/1601287974647/OSCB-Berlin_%C2%A9-ENK_UNSCHARF-SEHEN---do-you-also-suffer-%2B-BLINK%2C-Blinzeln_4_10-17-0%2C2_.gif ESSENTIALS for Dry Eyes Visual disturbances in dry eyes typically get better after blinking the eye - but only temporarily. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887dea5/1601285809074/Animation-OFFICE-EYE_10-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif ESSENTIALS for Dry Eyes https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa5498f92a52c2fe887de81/1605097949742/1_OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg ESSENTIALS for Dry Eyes With severe dryness and soreness of the eyes, the feeling of a parched desert floor which cracks open painfully can set in. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fae7d949488406ed9a58750/1605270945327/OSCB-Berlin.org-%28c%29-ENK_ANIMATION_OCULAR%2BSURFACE-AND-TEARS-%2B-AUGE-QUER%2BFrontal_ENGLISCH_10-8-3_NEU_E.gif ESSENTIALS for Dry Eyes https://oscb-berlin.org/e-nervous-system-blink-pain daily 0.75 2020-12-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa599562695d34ca4c8b820/1603739258291/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Dry%2BEye%2BDisease_Trockenes%2BAuge_NERVENREIZUNG%2Bbei%2BEPITHELSCH%C3%84DIGUNG%2B%2B%2BGEHIRN_20_.jpg Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fccde72978da30c56fccc27/1607262472645/OSCB%2C-ENK_LIDER-%28FRONTAL%29-Animation-BLINZELN_%28aus-KL-Weich%29__DRY-SPOT-FLUO_NEU-K%C3%BCrzer_20-18-0%2C2_.gif Nervous System, Blink, and Pain The break-up of the thin tear film becomes visible when the tears are stained with the fluorescein dye that is observed in blue light. A break-up occurs as a dark area (seen here in the middle of the faint “C” of the OSCB overlay). The break-up of the tear film is the stimulus that triggers an eyelid blink in order to distribute a new tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa599562695d34ca4c8b82f/1603743209785/ANIMATION_OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29_aus-BLINZELN_%28aus-KL-Weich%29_Folie-VERKL.25b-x-25cm-h-ALS-Gr%C3%B6sse-Opt.%2BNEU-MAN_600-13-0%2C2_%2B%281%29+%282%29.gif Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa66af50feb651389247057/1604741894647/Animation_Augenoberfl%C3%A4che-NERVENSYSTEM-Schmerz_Ocular-Surface-NERVOUS-SYSTEM-Pain_ENGLISCH_Einzel-BILDER_600pix-21-2_.gif Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa6782392c73f0939a7eb89/1604745264262/OSCB-Berlin.org-%28c%29-ENK_GIF-FUNCTIONAL-UNIT-Animation-TEARS-REGULATION_aus-GIF-Funct.-Unit_20-2-1_.gif Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa599562695d34ca4c8b826/1603746722809/OSCB-Berlin.org_%28c%29%2BENK_LIDER-%28FRONTAL%29-Animation%2C%2BBLINZELN_%2BTr%C3%A4nenfluss-mit-Gelbem-Zettel_FEUCHTES-Auge%2C-Epiphora_10-10-0%2C2_.gif Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa599562695d34ca4c8b82c/1603739944415/Animation-OFFICE-EYE_600-12-0%2C4_10-LINK-Bildchen_OSCB-Berlin.org_%28c%29ENK_.gif Nervous System, Blink, and Pain https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fa66a02116faf366cae61f7/1604741638127/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_REGULATION-SYSTEMS-for-the-Ocular-Surface---The-NERVOUS-SYSTEM.gif Nervous System, Blink, and Pain https://oscb-berlin.org/e-therapy-overview daily 0.75 2021-03-04 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad6d634aff1f2f85e8c070/1614852502526/Therapy-Options_EYELID+and+BLINKING+LBD_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad91684aff1f2f85f0c4f9/1614852902270/Therapy-Options_INTERNAL+Risk+Factors+%28links%29_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad6e6416947a58feab7fb8/1614852458556/Therapy-Options_EXTERNAL+Risk+Factors+%28links%29_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad7798162257496b2578e0/1614852811266/Therapy-Options_TEAR+FILM+DEFICIENCY_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad77789d560157704ac2ba/1614852931450/Therapy-Options_SURFACE+DAMAGE_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad911424c06f537382313b/1614852750671/Therapy-Options_LACRIMAL+GLAND+Damage_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad6cad36358572f1f8c9e4/1614852410208/Therapy-Options_NERVOUS+SYSTEM+Regulation+Pain_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faedcabdd1d4d05200f36b2/1605445590063/OSCB-Berlin.org_aus+ANIMATION_Krankheits-Faktoren+THERAPIE-OPTIONEN_Disease+Factors+and+Therapy+Options_ENGLISCH+%28mehr+Beschriftung%29_2_30__.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad913a64ed982990df6164/1614852870916/Therapy-Options_MEIBOMIAN+GLAND+DYSFUNCTION%2C+MGD_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faedcf003633f0646b63c29/1614853007110/Therapy-Options_REGULATORY+SYSTEMS+Endocrine+%2B+Immune_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad6e8516932f1df5abdf9b/1614852533895/Therapy-Options_EXTERNAL+Risk+Factors+%28rechts%29_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faedc3769c60d415b2befe7/1605438314143/OSCB-Berlin.org_ANIMATION_Krankheits-Faktoren-THERAPIE-OPTIONEN_Disease-Factors-and-Therapy-Options_ENGLISCH-%28mehr-Beschriftung%29_2_20-21-1%2C5_.gif Therapy OPTIONS The animated image shows how basic functional complexes maintain eye health and how their disruption leads to the development of dry eyes. At the same time, the understanding of the origin of the disease gives rise to approaches for successful therapy. => go directly to Disease Factors and Therapy Selection https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad91fc162257496b2bd42c/1614852964330/Therapy-Options_INTERNAL%2BRisk%2BFactors%2B%2528rechts%2529_Link-Bildchen_.jpg Therapy OPTIONS https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fad658d54d01722c165a4c5/1580155203008/ZIELGRUPPEN-Symbol-Bilder%2BVERSCHIEDENE%2B4%2BARZT%2Bmit%2BAuge_NEU%2B2_16%2BLINK%2BBILDCHEN_Therapie_.jpg Therapy OPTIONS https://oscb-berlin.org/e-therapy-steps daily 0.75 2021-07-02 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbe35163c6ccf69f32994ce/1606301895530/OSCB-Berlin.org+%28c%29+ENK_TROCKENES+AUGE%2C+Sehr+SCHWER%2C+very+severe+DRY+EYE%2C+BLEPHARITIS_20_.jpg WHAT to DO ? - STAGGERED Therapy ! Image of a very severe dry eye that shows corneal opacities, ingrowth of blood vessels, beginning conjunctivalization, in addition there is a chronic blepharitis. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015038/5faf991a54d7bd32ba01503d/1615534220568/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+D%C3%9CNNfl%C3%BCssige+Tropfen_10+LINK+BILDCHEN_.jpg WHAT to DO ? - STAGGERED Therapy ! - Tear Supplements (artificial tars) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015038/5faf991a54d7bd32ba01503b/1605439477328/OSCB-Berlin.org%2C+%28c%29+ENK_Risikofaktoren+VERMEIDEN_10+LINK+BILDCHEN_.jpg WHAT to DO ? - STAGGERED Therapy ! - Avoid Risk Factors https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015038/5faf991a54d7bd32ba01503f/1605439640313/OSCB-Berlin.org%2C+%28c%29+ENK_INFO_10+LINK+BILDCHEN_.jpg WHAT to DO ? - STAGGERED Therapy ! - Information https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015038/604b53456f62fe1df5cf6e24/1615549312416/Unbenannt-2.jpg WHAT to DO ? - STAGGERED Therapy ! - Basic Eyelid Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/605e204e5c11d47c885a1cba/1616781426040/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_10-12-1%2C3_+%281%29.gif WHAT to DO ? - STAGGERED Therapy ! - Punctum Plugs https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/605e201cdaf280668a9a9335/1616781374265/STUFEN%2BTHERAPIE%2C%2BVERSCHREIBUNGSPFLICHTIGE%2BARZNEIMITTEL__.jpg WHAT to DO ? - STAGGERED Therapy ! - Prescription Medicine https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/5fb01bd09d56015770a3c685/1615534460362/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Tr%C3%A4nenersatz%2C%2BD%C3%9CNNfl%C3%BCssige%2BTropfen%2BST%C3%9CNDLICH_10%2BLINK%2BBILDCHEN_OT_.jpg WHAT to DO ? - STAGGERED Therapy ! - frequent tear supplements https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/5faf991a54d7bd32ba015044/1615534470861/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+DICKfl%C3%BCssiges+GEL+zur+NACHT_10+LINK+BILDCHEN_.jpg WHAT to DO ? - STAGGERED Therapy ! - GEL at Night https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/5faf991a54d7bd32ba015048/1615534760022/IPL-Animation_Intense-Pulsed-Light_%28c%29ENK%2C-www.OSCB-Berlin.org_400-15-1_.gif WHAT to DO ? - STAGGERED Therapy ! - app. Lid Therapy: IPL, LLLT https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba015043/5faf991a54d7bd32ba015046/1615534478834/lipiflow-animation_8-48-0%2C05_.gif WHAT to DO ? - STAGGERED Therapy ! - app. Lid Therapy Lipiflow https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba01504e/5fb01cda08f95b782a71e4c6/1615534960357/OSCB-Berlin.org+%28c%29+ENK_Eye+Foto+with+PUNCTUM+PLUGS+Zeichnung_AUSSCHNITT_10_.jpg WHAT to DO ? - STAGGERED Therapy ! - Punctum Plugs https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba01504e/5faf991a54d7bd32ba015055/1614851685083/STUFEN+THERAPIE%2C+VERSCHREIBUNGSPFLICHTIGE+ARZNEIMITTEL__.jpg WHAT to DO ? - STAGGERED Therapy ! - prescription medicine https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba01504e/5faf991a54d7bd32ba01504f/1615534987131/OSCB-Berlin.org%2C+%28c%29+ENK_Tr%C3%A4nenersatz%2C+DICKfl%C3%BCssiges+GEL+TAGS+%2B+NACHTS_10+LINK+BILDCHEN_.jpg WHAT to DO ? - STAGGERED Therapy ! - Gel for Day &amp; Night https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5faf991a54d7bd32ba01504e/605e2cd9a4140e6814f1a2ea/1616784668656/Animation+sklarale+Linse+%2B+Lidschlag.gif WHAT to DO ? - STAGGERED Therapy ! - Scleral Contact Lens https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb009940e8bbf646f4bff0f/1605372321131/Therapy+Options+ENGLISCH_Mild-Moderate-Severe_%C3%9Cbersicht_40_.jpg WHAT to DO ? - STAGGERED Therapy ! https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5faf991a54d7bd32ba015033/1605437774276/Diagnostik+und+Therapie%2C+Abbildung+f%C3%BCr+LINK+BANNER_3+f%C3%BCr+Erkennen+%26+Behandeln%2C+Patient%2C+Arzt%2C+Fragezeichen%2C+Schlange+%2B+3D+W%C3%9CRFEL+f%C3%BCr+Stufentherapie_.jpg WHAT to DO ? - STAGGERED Therapy ! https://oscb-berlin.org/e-lacrimal-gland-dysfunction daily 0.75 2021-03-04 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce462cd235d37878f370b9/1607364875330/PUNCTUM+PLUGS_10+LINK+BILDCHEN_.jpg Lacrimal Gland Failure - Severe dryness => directly to therapy selection https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fb80e9007ae9c7f2c926c1d/1606496601694/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_20-12-1%2C3_.gif Lacrimal Gland Failure - Severe dryness Eye and lacrimal drainage system. The tear drainage system begins on each lid at the tear point (lacrimal punctum), which is at the nasal side immersed into the tear lake (tear meniscus) to be able to suck up tear fluid. The lacrimal canaliculus runs from here within the edge of the eyelid towards the nose and both canaliculi unite in front of the lacrimal sac. The sack extends as the naso-lacrimal duct into the nose where the tears enter the nasal passage. If there is a very strong lack of aqueous tears, a punctum plug inside the tear point is useful to inhibit the removal of tear fluid from the eye. The pugging thus increases the height of the tear meniscus (´TMH´, please see in the animated image), which can be clinically measured as TMH-Test (=> here is more information with histological images) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce1dcdcded405bb800a479/1607343577096/OSCB-Berlin.org+%28c%29+ENK_PUNCTUM+PLUGS+various+types+-+PUNCTUM+PLUGS+verschiedene+Typen_AIVIMED_20_.jpg Lacrimal Gland Failure - Severe dryness https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce457124c49707d34ce374/1607353767920/PUNCTUM+PLUGS_10+LINK+BILDCHEN_.jpg Lacrimal Gland Failure - Severe dryness => here is a selection of therapy options https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fce48b1fe657040d5c05c71/1607354555524/OSCB-HomePage_PUNCTUM-PLUGS%2C-Lacrimal-Drainage-System_ANIMATION_2_CROP-Schmal-2_35-9-1_.gif Lacrimal Gland Failure - Severe dryness https://oscb-berlin.org/d-physical-therapy daily 0.75 2020-12-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fba9d4fb41d97178880a570/5fba9def32611c2ac1b41f4d/1606124044414/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_%2B%281%29+%281%29.gif MEIBOMDRÜSEN & AugenLider - Physikalische Therapie - Lidrand HYGIENE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fba9d4fb41d97178880a570/5fba9dc0a4ebbd103bb5bb72/1606124044410/OSCB-Berlin.org%2B%28c%29-ENK_Physical%2BTherapy%2B-%2BLID%2BMASSAGE_10_+%281%29.jpg MEIBOMDRÜSEN & AugenLider - Physikalische Therapie - Lid MASSAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fba9d4fb41d97178880a570/5fba9d6560ed88028bd72afe/1606124044404/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_%2B%281%29+%281%29.gif MEIBOMDRÜSEN & AugenLider - Physikalische Therapie - WÄRMUNG https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb657a32611c2ac1d0b740/1606124044417/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_600pix-8-2%2C5+%282%29.gif MEIBOMDRÜSEN & AugenLider - Physikalische Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb67982b4bfe31fd881065/1606124044422/Download+%282%29.gif MEIBOMDRÜSEN & AugenLider - Physikalische Therapie https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb66eed89f9c06277bf274/1606124044419/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG+%281%29.gif MEIBOMDRÜSEN & AugenLider - Physikalische Therapie https://oscb-berlin.org/e-physical-therapy daily 0.75 2021-02-22 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb820c5779397619f20874/1606117329986/Download+%282%29.gif MEIBOMIAN GLANDS & Eyelids - Physical Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fbb820c5779397619f20864/5fbb820c5779397619f20867/1606124174190/OSCB-Berlin.org%2B%28c%29-ENK_Physical%2BTherapy%2B-%2BLID%2BMASSAGE_10_+%281%29.jpg MEIBOMIAN GLANDS & Eyelids - Physical Therapy - Lid MASSAGE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fbb820c5779397619f20864/5fbb820c5779397619f20869/1606124200864/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_%2B%281%29+%281%29.gif MEIBOMIAN GLANDS & Eyelids - Physical Therapy - Lidrand HYGIENE https://static1.squarespace.com/static/58591aed3e00bedc063f7303/5fbb820c5779397619f20864/5fbb820c5779397619f20865/1606124164228/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_10-8-1_%2B%281%29+%281%29.gif MEIBOMIAN GLANDS & Eyelids - Physical Therapy - WARMING https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb820c5779397619f2086e/1606117349957/GIF-Animation-PHYSIKALISCHE-THERAPIE%2C-W%C3%84RMUNG_DEUTSCH_600pix-8-2%2C5+%282%29.gif MEIBOMIAN GLANDS & Eyelids - Physical Therapy https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbb820c5779397619f20871/1606117340188/OSCB_LIDER-%28FRONTAL%29-Animation-%28ENK%29-LIDRANDMASSAGE_aus-BLINZELN_%28aus-KL-Weich%29__4____MIT-OSCB%2BZETTEL---FERTIG+%281%29.gif MEIBOMIAN GLANDS & Eyelids - Physical Therapy https://oscb-berlin.org/e-lidcare daily 0.75 2021-03-28 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc9703/1606840837586/LIDRAND+Foto+IMG_0287+RET_MON+mit+ABLAGERUNGEN+an+WIMPERN%2C+ev.+DEMODEX+2+%2BFREIER+Lidrandschmutz+heller_20_.jpg EYELID - Hygiene & Care Lid Margin with depositions and incrustations on the free margin and at the base of the eyelashes. Depositions of sticky material often glue the eyelashes together in bundles. An animated figure explains how the depositions build up on the eyelid margin in disease states. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc24e44e18c5c478e46fae3/1606572076660/OSCB-Berlin.org_%2528c%2529%2BENK-%2BErich%2Band%2BNadja%2BKnop_Dry%2BEye%2BDisease%252C%2BTrockenes%2BAuge_Meibomdr%25C3%25BCsen%2BDysfunktion%2B%2528MDD%252C%2BMGD%2529%2Bmit%2Bverstopften%2Bund%2Birregul%25C3%25A4ren%2B%25C3%2596ffnungen%2Beingedicktes%2BSekret%2Bwird%2Bausgepresst_20_.jpg EYELID - Hygiene & Care Blockade of the Meibomian gland openings. Inspissated oil can occur inside the glands with whitish ´pointing´ of the orifices (white dots upper image) or it can protrude out of the openings onto the eyelid margin (lower image). A gland obstruction can, however, often be non-obvious without further investigations. ()termed as NOMGD) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc9706/1580155538572/OSCB-Berlin.org_%28c%29+ENK_LIDRAND+287+gedr-li_.jpg EYELID - Hygiene & Care https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc96fd/1607530841866/OSCB-Berlin.org%2C+%28c%29+ENK_Lid-Hygiene+%26+Lid-Care+Products_BANNER_.jpg EYELID - Hygiene & Care => directly to the therapy options https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fc1398008845d0924b72427/1606498701818/OSCB-Berlin.org%2C-%28c%29-ENK_LIDRAND-HYGIENE-mit-Finger_10-34-0%2C15_%28OHNE-Text%29_.gif EYELID - Hygiene & Care https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc9700/1606495465781/OSCB-Berlin.org_%28c%29ENK_Der+LIDRAND+-+The+LID+MARGIN_ohne+Text+2_20_.jpg EYELID - Hygiene & Care The edge of the eyelid (eyelid margin) extends from the outer border with the eyelashes over the free margin of the eyelid (... where the kajal pencil can be applied in cosmetics ;-) to the inner border that is in contacts with the eyeball. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc970c/1606494809941/www.OSCB-Berlin.org_ABLAGERUNGEN+und+VERKRUSTUNGEN+auf+dem+Lidrand+bei+Meibomdr%C3%BCsen+St%C3%B6rung%2C+MDD%2C+MGD+und+BLEPHARITIS+2_20_.jpg EYELID - Hygiene & Care On the eyelid margin are the openings of several glands. In the front are the hair-associated glands (m, at the right side of the image) around the roots of the eyelashes and at the inner lid border open the Meibomian oil glands. In disease conditions the gland products accumulated on the lid margin together with dust and other debris and provides an nutritious environment for bacteria and demodex hair mites. Altogether this favours inflammation and worsening of the condition (please see an animated image how this develops). That´s why Lidcare is an important component of prevention and therapy for chronic dry eyes, Meibomian gland dysfunction (MGD) and blepharitis. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbeab822dd96f5918cc9712/1606577190278/OSCB-Berlin.org%2C%2B%28c%29%2BENK_Lid-Hygiene%2B%26%2BLid-Care%2BProducts_BANNER_+%281%29.jpg EYELID - Hygiene & Care https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fbf794bf81c9a2a0c9bd053/1606383951874/LIDRAND+Foto+20200114125329_IMG_0287+RET_30_.jpg EYELID - Hygiene & Care https://oscb-berlin.org/overview-on-the-lid-margin daily 0.75 2020-12-19 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca0af9be6684539df05f27/1608464745484/GIF-Animation_TYPICAL-SYMPTOMS-in-DRY-EYE-DISEASE_Typische-Symptome-beim-Trockenen-Auge_Bild-ENGLISCH-1-4v4_KURZ_10-72_5-1%2C5_.gif OVERVIEW on ...the Lid Margin The entire surface of the eye is an integrated functional system ... in which all parts have to function in order to maintain overall health and thus clear vision. Disturbances of the edge of the eyelid, especially in the area of the rear edge of the eyelid, can significantly disrupt the stability of the tear film, as (1) it can only be made thin and even by the lid wiper of the rear edge of the eyelid and (2) the tear film on the rear edge of the eyelid as Base rests. Dry eye can be a typical consequence of disorders of the lid edge. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca0a0b55485c3109b7ad02/1608464745481/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_OSCB-Bild_5.4.1_The-Lid-Marginn_LID-WIPER-Topography%2C-aus-CORNEA-2012_.gif OVERVIEW on ...the Lid Margin The inner part of the posterior lid border is in contact with the globe (figure A) and is termed as the ´lid wiper´ because it wipes over cornea and distributes the tears into the tear film. Histologic investigations have shown that the epithelium forms a slightly elevated epithelial lip (figure B) similar to a windscreen wiper (figure C). The lid wiper is thus ideally suited for spreading a very thin tear film. (here is a respective publication) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca08512f5dbb44b781cf91/1608464745473/OSCB-Bild_5..3.0_Lid+Margin_The+Eye+Lid+Margin+in+Clinical+Photos_aus+Ophthalmologe+2009_als+JPG+20_.jpg OVERVIEW on ...the Lid Margin The eyelid margin is seen here in clinical photos. The anterior border with the eyelashes (in figure A, the lid is slightly everted) is followed by the smooth strip of the free lid margin without hairs (figure on the right side, the lid is in normal position). The posterior border is rather sharp (open arrow in figure B, the lid is everted) and in normally in contact with the eyeball. The Meibomian glands are seen as whitish tissue streaks through the translucent tarsal conjunctiva (in figure B). The openings of the glands onto the lid margin are seen as a line of little dots close to the posterior lid border (indicated by an open arrow in figures A and B). They are seen in higher enlargement in a following figure. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca06d02f5dbb44b781aa0a/1608464745469/OSCB-Berlin.org_%28c%29ENK_Der+LIDRAND+-+The+LID+MARGIN_ohne+Text_20_.jpg OVERVIEW on ...the Lid Margin The edge of the eyelid - the eyelid margin - (arrows in the figure) limits at the opening of the eyelids (the interpalpebral fissure) through which the light can enter the eye for vision. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca170b8562787517620a7b/1608464745479/The+TEAR+MENISCUS+rests+on+the+Line+of+MARX%2C+Augenoberfl%C3%A4che%2C+Quer+und+EIGENE+Aufsichtzeichnung.png OVERVIEW on ...the Lid Margin The TEAR MENISCUS (blue arrows in all schematic drawings) is the clearly thickened ´END´ of the tear film where it touches the eyelid margin. The formation of the tear meniscus (´tear lake´), which contains more tear fluid than the tear film itself and is roughly triangular in cross-section (fig. Left), is related to the surface tension. In high magnification (excerpts on the far right) one can see that the tear meniscus lies on the MARX line (red-brown arrows, far left), which in turn is the surface of the skin-mucous membrane boundary (MCJ) - this is the anterior, first Zone of the posterior edge of the lid. The second, posterior, zone of the lid touches the eyeball / globe - there the marginal conjunctiva forms the thickened epithelial lip of the lid wiper, which pulls out the tears into a very thin tear film. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca03432e4d7f67ca301460/1602086198564/OSCB-Bild_5.4.2_The+Lid+Margin_5.4.3_The+lid+wiper+has+a+BUILT-IN+LUBRICATION+SYSTEM+of+goblet+cells+aus+CORNEA+2012.png OVERVIEW on ...the Lid Margin https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca0969ee6dcf7e3638064d/1608464745476/OSCB-Bild_5.2.4+NEU+3D+NEU+CLINICAL+vs.+HISTOLOGY_Lid+Margin_FREE+Lid+MARGIN+mit+PFEIL-LINIE+%2B+Inner+and+Outer+BORDER.png OVERVIEW on ...the Lid Margin The free lid margin points towards the opened eyelid fissure. It is limited at the front by the roundish outer lid border (OLB) and behind by the rather sharp rear posterior lid border (PLB). The posterior border is in contact with the eyeball and acts as a lid wiper to create and maintain a thin but stable tear film. The openings (orifices) of the Meibomian glands onto the posterior lid margin are marked be an open arrow in the figure on the right side. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca03432e4d7f67ca301463/1559214008848/ OVERVIEW on ...the Lid Margin The main function of the LID EDGE, apart from a protective function, is the MANAGEMENT of the tear fluid on the eye and its transformation into a tear film. (The flow of tears in this schematic representation is increased compared to normal and corresponds approximately to that when crying) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fca03432e4d7f67ca30144e/1483818740795/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28hier+hell+%2B+kontrastreich%29_NUR+UNTERES+DRITTEL+f%C3%BCr+BANNER.jpg OVERVIEW on ...the Lid Margin https://oscb-berlin.org/d-blick-auf-den-lidrand daily 0.75 2020-12-29 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf3b0691828d0f5d5606b8/1609259311311/OSCB-Berlin.org_%28c%29ENK_Der+LIDRAND+-+The+LID+MARGIN_ohne+Text+2_20_.jpg d-Blick auf den LIDRAND Der Lidrand (Pfeile) säumt die geöffnete Lidspalte und verbindet die äußere trocken-ölige Haut aussen mit der inneren wässrig-feuchten Schleimhaut https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf415591828d0f5d565c2f/1608486907272/OSCB-Berlin.org---%28c%29-ENK_LIDRAND+IMG_0287+RET+%2B+Gelber+Zettel_30.jpg d-Blick auf den LIDRAND Der Lidrand säumt die Lidspalte und verbindet die äußere trocken-ölige Haut mit der inneren wässrig-feuchten Schleimhaut des Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf7a1451a86c1b6c38101c/1609259812994/OSCB-Berlin.org_The-LID-MARGIN.gif d-Blick auf den LIDRAND Der freie Lidrand (flm) in der Mitte ist der grösste Bereich des Lidrandes. Er wird hinten und vorne durch je eine Lidkante begrenzt. Auf der runden vorderen/äusseren Lidkante befinden sich die Wimpern. Die scharfe hintere/innere Lidkante liegt am Augapfel. Die Öffnungen der Meibomdrüsen (offener Pfeil in der Bildmitte) münden kurz vor der Grenze zur hinteren Kante. Hinter den Drüsenöffnungen liegt die Haut-Schleimhaut Übergangszone (mjc). Danach folgt das etwas verdickte Epithelkissen des Lidwischers (lw), das auf dem Augapfel aufliegt. In diesem Foto ist der Lidrand etwas abgezogen vom Augapfel und daher wird der Lidwischer sichtbar. (Spaltlampen Foto) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf7e677514fb3b765ab694/1608482410727/image.jpg d-Blick auf den LIDRAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5feb7da94864e744207afb27/1609268810461/OSCB-Berlin.org+%28c%29+ENK_Two+aspects+of+lid+margin+function+-+STATIC+DAM+vs.+DYNAMIC+WIPER_OPT.jpg d-Blick auf den LIDRAND Der Lidrand kann auf die Tränenflüssigkeit wirken als statischer Damm (links) gegen das Auslaufen über den Lidrand und als dynamischer Wischer (rechts) zur Verteilung der Tränen in einen dünnen Tränenfilm. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf7e482baf317dc3a94a69/1608482380916/OSCB-Berlin.org%2B%2528c%2529%2BENK_Two%2Baspects%2Bof%2Blid%2Bmargin%2Bfunction%2B-%2BDYNAMIC%2BWIPER_.jpg d-Blick auf den LIDRAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fdf7e26c18bd5077cb5f52b/1608482349301/OSCB-Berlin.org%2B%2528c%2529%2BENK_Two%2Baspects%2Bof%2Blid%2Bmargin%2Bfunction%2B-%2BSTATIC%2BDAM_.jpg d-Blick auf den LIDRAND https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/5fde3c20ef735726d2543b85/1483818740795/Augenoberfl%C3%A4che+FOTO+EIGENES+AUGE+%28hier+hell+%2B+kontrastreich%29_NUR+UNTERES+DRITTEL+f%C3%BCr+BANNER.jpg d-Blick auf den LIDRAND https://oscb-berlin.org/tests-normalwerte daily 0.75 2021-03-24 https://oscb-berlin.org/d-diagnosis-normal-values daily 0.75 2021-03-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/6050d83765cc41625d924064/1615910970004/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg Diagnose - NORMALWERTE bei Tests für Trockene Augen https://oscb-berlin.org/e-diagnosis-normal-values daily 0.75 2021-03-16 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/6050de16c9e1850cd326b7f0/1615912473305/DIAGNOSE+Symbolbild+mti+Fragezeichen_3.jpg Diagnosis - NORMAL VALUES of Tests for Dry Eyes https://oscb-berlin.org/reserve-17621_fakten-infos-zum-trockenen-auge-copy daily 0.75 2021-06-17 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2ef/1605622808742/OSCB-Berlin.org%2C+%28c%29+ENK_Dry+Eye+Disease+MGD_Trockenes+Auge+mit+Meibomdr%C3%BCsen+Dysfunktion+%28MDD%29+und+LIPIDMANGEL+2+MGD_20_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) Der Tränenfilm auf der Augenoberfläche benötigt eine dünne Ölschicht (gelb, links im Bild) oben auf den wässrigen Tränen (blau, in der Mitte). Das Öl vermindert die Verdunstung des Tränenwassers. Ein Ölmangel erhöht die Verdunstung (blaue gewellte Pfeile, rechts im Bild) mit nachfolgender Reizung und Beschädigung des empfindlichen Gewebes (rötliche Färbung des Gewebes, rechts im Bild) sowie störenden Symptomen eines Trockenen Auges. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2f2/1605559883582/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) Die Augenlider und der Lidschlag sind ebenso wichtig für die Gesundheit des Auges wie die Tränen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d2f8/1581339852348/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - TROCKENES &amp; FEUCHTES Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d2fe/1567154445308/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - Tieferer EINBLICK (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d300/1567154445310/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - FAKTEN über das Trockene Auge (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d302/1605682164382/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease___Augenoberfl%C3%A4che+und+Dr%C3%BCsen_Ocular+Surface+and+Glands_%2B+MGD+%2B+W%C3%BCste+%2B+Kamele+50%25_10+LINK+BILDCHEN_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - Das WICHTIGSTE - Essentials (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d2fc/1567154445306/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - ÜBERBLICK (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb5002849d132e7611d2f7/60cb5002849d132e7611d2fa/1567154445303/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) - Kurzer BLICK (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2e9/1605616039007/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) Die Augenoberfläche mit den dazugehörigen Augenlidern. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2ec/1605683689044/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_400-6-0%2C8_.gif RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) Einige lästige Symptome Trockener Augen sind hier schematisch dargestellt, z.B. verschwommenes Sehen, Trockenheitsgefühl, Rötung, Stechen oder Brennen der Augen - hier finden Sie mehr Informationen über typische Symptome. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2f5/1605608580045/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) Viele austrocknende Umweltfaktoren kommen bei Büroarbeit zusammen und können zu einen “Büroauge” führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb5002849d132e7611d2e6/1567154445287/OSCB-Berlin.org_%2528c%2529ENK_Trockenes-Auge%252C-Dry-Eye-Disease_NORMALES%2BAUGE_Beispiel%2BFoto%2B%252B%2BW%25C3%25BCste%252BKamele%2B%252B%2BRand%2B-%2BHELLER_20_.jpg RESERVE 17.6.21_FAKTEN & INFOS zum Trockenen Auge (Copy) https://oscb-berlin.org/trockene-augen daily 0.75 2021-07-01 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60ccec983838956a5aba8dd1/1624042673437/Animation_Schema-Gewebeschaden%2C-Reizung%2C-Entz%C3%BCndung-3-%28Vitalf%C3%A4rbung-unauff%C3%A4lliger-%2B-weniger-R%C3%B6tung%29_19-9-0%2C7_.gif Trockene Augen - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb67df5c8b16039f32363f/1623948908335/Blink-Quer-Frontal-%2B-Tr%C3%A4nenABFLUSS_Einzelbilder_NEU_%2BZettel__570-8-0%2C4_.gif Trockene Augen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60de14511fb11f0d0fcd025b/1625166962239/Animation-MGD%2C-Meibomdr%C3%BCsen-Verstopfung-mit-Evaporation-%28aus-Einzelbild%29_EINZELBILDER_15-16-1%2C5_.gif Trockene Augen Wenn die Ölschicht aussen auf dem Tränenfilm (gelbe Schicht) weniger wird durch eine Störung der Meibom-Öldrüsen in den Augenlidern, dann verdunstet das Tränenwasser schneller (gewellte Pfeile rechts) und das Auge wird gereizt und rötet sich. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60ccefa2acc7d86e53eb3b6e/1624043450284/OSCB-Berlin.org_ANIMATION-KRANKHEITSFAKTOREN-und-THERAPIE-OPTIONEN_20-21-1%2C5_.gif Trockene Augen - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb67df5c8b16039f323639/1624727847601/Typische-Symptome-beim-Trockenen-Auge_NEUE-Animation-OHNE-TEXT_2_400-6-0%2C8_.gif Trockene Augen => hier finden Sie mehr Informationen zu Beschwerden bei Trockenen Augen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f32364e/1605682164382/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease___Augenoberfl%C3%A4che+und+Dr%C3%BCsen_Ocular+Surface+and+Glands_%2B+MGD+%2B+W%C3%BCste+%2B+Kamele+50%25_10+LINK+BILDCHEN_.jpg Trockene Augen - Das WICHTIGSTE - Essentials (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f323650/1567154445310/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease_NORMALES+AUGE_Beispiel+Foto+%2B+W%C3%BCste%2BKamele+%2B+Rand_10_.jpg Trockene Augen - FAKTEN über das Trockene Auge (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f32364a/1567154445308/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Scientists_10+LINK+BILDCHEN_.jpg Trockene Augen - Tieferer EINBLICK (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f323648/1567154445306/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Doctors_10+LINK+BILDCHEN_.jpg Trockene Augen - ÜBERBLICK (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f32364c/1567154445303/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+Patients_10+LINK+BILDCHEN_.jpg Trockene Augen - Kurzer BLICK (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/60cb67df5c8b16039f323645/60cb67df5c8b16039f323646/1581339852348/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse____Zielgruppe+ALLE_10+LINK+BILDCHEN_.jpg Trockene Augen - TROCKENES &amp; FEUCHTES Auge (Copy) (Copy) https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb67df5c8b16039f323643/1605608580045/Animation-OFFICE-EYE_600-12-0%2C4_OSCB-Berlin.org_%28c%29ENK_.gif Trockene Augen Viele austrocknende Umweltfaktoren kommen bei Büroarbeit zusammen und können zu einen “Büroauge” führen. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60ccee3d42cedf4d40d33064/1624892779457/Diagnostik+und+Therapie%2C+Abbildung+f%C3%BCr+LINK+BANNER_3+f%C3%BCr+Erkennen+%26+Behandeln%2C+Patient%2C+Arzt%2C+Fragezeichen%2C+Schlange+%2B+3D+W%C3%9CRFEL+f%C3%BCr+Stufentherapie_.jpg Trockene Augen - Make it stand out Verschiedene ´Bausteine´ tragen zur effektiven Therapie des Trockenen Auges bei https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb75a42927677d75483568/1623946671792/Animation-TR%C3%84NENFLUSS-an-der-Augenoberfl%C3%A4che%2C-Functional-Unit_2-1_Einzel-BILDER_Voll-2-1_+%283%29.gif Trockene Augen - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb67df5c8b16039f323636/1624727394127/Animation_Trocknes-Auge%2C-Dry-Eye_Einfach%2C-Zum-Einstieg-f%C3%BCr-FACTS_Zugeschnitten%2B600_15-600-0%2C3.gif Trockene Augen Die Augenoberfläche mit den dazugehörigen Augenlidern. Mangelnde Befeuchtung führt zu Trockenen Augen mit Reizung und vermehrter Sichtbarkeit der Gefässe. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cced80acc7d86e53eb1b51/1624724955510/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse_NORMALES-AUGE_Beispiel-Foto_.gif Trockene Augen - Make it stand out Ein praktisch normales Auge. Bei genauem Hinsehen kann man eine leicht vermehrte Füllung der Gefässe in der Bindehaut beobachten - in diesem Fall bei Kontaktlinsentragen - dies ist nicht bedrohlich. Beim Auftreten von Beschwerden eines Trockenen Auges kann dies aber ein Grund sein, die Ursache festzustellen und deren Einwirkung zu vermindern - also hier z.B. eine Reduzierung der Tragezeit der Kontaktlinsen oder ggf. eine Pause ihrer Nutzung. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb6e7b93d35a677a364927/1624728029569/OSCB-Berlin.org+%28c%29+ENK_Tr%C3%A4nenfilm+und+Augenoberfl%C3%A4che_j6_.jpg Trockene Augen - Make it stand out Die verschiedenen Schichten des Tränenfilms erhalten die Augenoberfläche gesund => hier bekommen Sie mehr Informationen zur Augenoberfläche https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cceefbfa75fd682255b4b2/1624726623974/OSCB-Berlin.org_%28c%29ENK_Trockenes-Auge%2C-Dry-Eye-Disease%2C-Contact-Lens%2C-Kontaktlinse__Einige-THERAPIE-OPTIONEN-f%C3%BCr-das-TROCKENE-AUGE_WEB-30_.gif Trockene Augen - Make it stand out Tränenersatzmittel inklusive Öl (links), eine regelmässige Wärmung und Massage der Augenlider (mitte) und eine regelmässige Reinigung und Pflege der Lidränder mit den Wimpern (rechts) sind typische Bestandteile einer modernen und wirkungsvollen Therapie für Trockene Augen und damit verbundene Störungen. Eine erkennbare Besserung kann aber erst eintreten, wenn die Therapie mindestens über einige Wochen regelmässig durchgeführt wird. https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60cb67df5c8b16039f323633/1567154445287/OSCB-Berlin.org_%2528c%2529ENK_Trockenes-Auge%252C-Dry-Eye-Disease_NORMALES%2BAUGE_Beispiel%2BFoto%2B%252B%2BW%25C3%25BCste%252BKamele%2B%252B%2BRand%2B-%2BHELLER_20_.jpg Trockene Augen https://oscb-berlin.org/d-sjogren-syndrom daily 0.75 2021-07-06 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/60e2f91f481661355c2e5090/1625574085195/Henrik+SJ%C3%96GREN_Download.jpg Tränendrüsen Störung - SJÖGREN Syndrom - Make it stand out Henrik SJÖGREN, schwedischer Augenarzt, der als erster die nach ihm benannte entzündliche Erkrankung der Tränen- und Speicheldrüsen in Kombination mit rheumatischer Erkrankung (Arthritis) beschrieben hat.. https://oscb-berlin.org/d-ocular-allergy daily 0.75 2021-07-11 https://oscb-berlin.org/e-mgd-duct-probing daily 0.75 2021-08-24 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/61235e05b422a5170e659782/1629721332732/Animation-Meibomdr%C3%BCsen-MGD---DUCT-PROBING-%28mit-BLUTUNG%29_20-11-1_.gif MGD - Surgical DUCT PROBING - Make it stand out Probing the meibomian glands carries an inherent risk of tissue injury, e.g. with minor bleeding https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/6123598e2c6b88112ca0cccc/1629721276989/Animation-Meibomdr%C3%BCsen-MGD---DUCT-PROBING_20-10-1_.gif MGD - Surgical DUCT PROBING - Make it stand out Probing of the Meibomian glands is a surgical therapeutic option for the removal of stubborn blockages in the glands https://oscb-berlin.org/d-mgd-duct-probing daily 0.75 2021-08-24 https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/612363c2a717487bc7699e5d/1629721280902/Animation-Meibomdr%C3%BCsen-MGD---DUCT-PROBING_20-10-1_.gif Meibomdrüsen - SONDIERUNG (duct probing) - Make it stand out Die Sondierung der Meibomdrüsen ist eine chirurgische Therapiemöglichkeit zur Beseitigung von hartnäckigen Verstopfungen in den Drüsen https://static1.squarespace.com/static/58591aed3e00bedc063f7303/t/612363c2a717487bc7699e60/1629721345409/Animation-Meibomdr%C3%BCsen-MGD---DUCT-PROBING-%28mit-BLUTUNG%29_20-11-1_.gif Meibomdrüsen - SONDIERUNG (duct probing) - Make it stand out Sondierung der Meibomdrüsen birgt ein Risiko für Gewebeverletzungen, z.B. mit kleineren Blutungen